LOCUS       XM_011539650            2433 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens DNA polymerase lambda (POLL), transcript
            variant X1, mRNA.
ACCESSION   XM_011539650
VERSION     XM_011539650.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000010.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011539650.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2433
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     gene            1..2433
                     /gene="POLL"
                     /gene_synonym="BETAN; POLKAPPA"
                     /note="DNA polymerase lambda; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 60
                     ESTs, 103 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     40 samples with support for all annotated introns"
                     /db_xref="GeneID:27343"
                     /db_xref="HGNC:HGNC:9184"
                     /db_xref="MIM:606343"
     CDS             114..1862
                     /gene="POLL"
                     /gene_synonym="BETAN; POLKAPPA"
                     /codon_start=1
                     /product="DNA polymerase lambda isoform X1"
                     /protein_id="XP_011537952.1"
                     /db_xref="GeneID:27343"
                     /db_xref="HGNC:HGNC:9184"
                     /db_xref="MIM:606343"
                     /translation="MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSL
                     RAHVVRTGIGRARAELFEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQ
                     LPPGAQLVKSAWLSLCLQERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEA
                     LLQTALSPPPPPTRPVSPPQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGH
                     YPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRA
                     LGYAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPV
                     LELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEA
                     TEIEQTVQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDS
                     LRQEAVPSVGPGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFAC
                     ALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDV
                     FRLLGLPYREPAERDW"
     polyA_site      2433
                     /gene="POLL"
                     /gene_synonym="BETAN; POLKAPPA"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 tgactcggaa gctattctgg ccatttgccc tccttccccc cttcgtccgc tctcattggc
       61 tctgctgcag ccctgaccaa cgctccaata ggccgggatc cagccatact tcaatggatc
      121 ccaggggtat cttgaaggca tttcccaagc ggcagaaaat tcatgctgat gcatcatcaa
      181 aagtacttgc aaagattcct aggagggaag agggagaaga agcagaagag tggctgagct
      241 cccttcgggc ccatgttgtg cgcactggca ttggacgagc ccgggcagaa ctctttgaga
      301 agcagattgt tcagcatggc ggccagctat gccctgccca gggcccaggt gtcactcaca
      361 ttgtggtgga tgaaggcatg gactatgagc gagccctccg ccttctcaga ctaccccagc
      421 tgcccccggg tgctcagctg gtgaagtcag cctggctgag cttgtgcctt caggagagga
      481 ggctggtgga tgtagctgga ttcagcatct tcatccccag taggtacttg gaccatccac
      541 agcccagcaa ggcagagcag gatgcttcta ttcctcctgg cacccatgag gccctgcttc
      601 agacagccct ttctcctcct cctcctccca ccaggcctgt gtctcctccc caaaaggcaa
      661 aagaggcacc aaacacccaa gcccagccca tctctgatga tgaagccagt gatggggaag
      721 aaacccaggt tagtgcagct gatctggaag ccctcatcag tggccactac cccacctccc
      781 ttgagggaga ttgtgagcct agcccagccc ctgctgtcct ggataagtgg gtctgtgcac
      841 agccctcaag ccagaaggcg accaatcaca acctccatat cacagagaag ctggaagttc
      901 tggccaaagc ctacagtgtt cagggagaca agtggagggc cctgggctat gccaaggcca
      961 tcaatgccct caagagcttc cataagcctg tcacctcgta ccaggaggcc tgcagtatcc
     1021 ctgggattgg gaagcggatg gctgagaaaa tcatagagat cctggagagc gggcatttgc
     1081 ggaagctgga ccatatcagt gagagcgtgc ctgtcttgga gctcttctcc aacatctggg
     1141 gagctgggac caagactgcc cagatgtggt accaacaggg cttccgaagt ctggaagaca
     1201 tccgcagcca ggcctccctg acaacccagc aggccatcgg cctgaagcat tacagtgact
     1261 tcctggaacg tatgcccagg gaggaggcta cagagattga gcagacagtc cagaaagcag
     1321 cccaggcctt taactctggg ctgctgtgtg tggcatgtgg ttcataccga cggggaaagg
     1381 cgacctgtgg tgatgtcgac gtgctcatca ctcacccaga tggccggtcc caccggggta
     1441 tcttcagccg cctccttgac agtcttcggc aggaagcagt cccctctgtt gggccagggt
     1501 tcctcacaga tgacttggtg agccaagagg agaatggtca gcaacagaag tacttggggg
     1561 tgtgccggct cccagggcca gggcggcggc accggcgcct ggacatcatc gtggtgccct
     1621 atagcgagtt tgcctgtgcc ctgctctact tcaccggctc tgcacacttc aaccgctcca
     1681 tgcgagccct ggccaaaacc aagggcatga gtctgtcaga acatgccctc agcactgctg
     1741 tggtccggaa cacccatggc tgcaaggtgg ggcctggccg agtgctgccc actcccactg
     1801 agaaggatgt cttcaggctc ttaggcctcc cctaccgaga acctgctgag cgggactggt
     1861 gacccatggc tgggggtgct gaggagagcc gagttggact ggctacccct cctggccacc
     1921 cagtactccc tccagcctca gctggctgaa cctcgccgct ccaaccacca gcttcctcag
     1981 cgagcagggc ccagggctct gggcctgaag caagagccag cccggctccc agtgtctgcc
     2041 cggctcccag tgtctgccca gccctctccc agacaggagc aggctgccac cccttctacc
     2101 tcaccactgc ccctcgaaga attttgcaaa tggccccttg ccccatttta agcaggagca
     2161 ggtggctggt ttgaagcccc aggtatcccc cttccctgct atgggaaagg ccaagctgct
     2221 gggtggggac agaagctgca ggggagaggg aagcagccgt gctgtcaaca tcatccggca
     2281 ccctctgggg taggagaaca gccattccac atgtgttccc tctatccgtc ctgcttcctg
     2341 ggcagctggt ggtgctggga atggggtgcc ccagccttgg tgaggacagt gttgggaggc
     2401 ccaggggccc agtaaagtgc atttgacatt gaa
//
