LOCUS       NM_001099271            2185 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens POC5 centriolar protein (POC5), transcript variant 1,
            mRNA.
ACCESSION   NM_001099271
VERSION     NM_001099271.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2185)
  AUTHORS   Arslanhan,M.D., Cengiz-Emek,S., Odabasi,E., Steib,E., Hamel,V.,
            Guichard,P. and Firat-Karalar,E.N.
  TITLE     CCDC15 localizes to the centriole inner scaffold and controls
            centriole length and integrity
  JOURNAL   J Cell Biol 222 (12) (2023)
   PUBMED   37934472
REFERENCE   2  (bases 1 to 2185)
  AUTHORS   Hassan,A., Bagu,E.T., Patten,S.A., Molidperee,S., Parent,S.,
            Barchi,S., Villemure,I., Tremblay,A. and Moldovan,F.
  TITLE     Differential Regulation of POC5 by ERalpha in Human Normal and
            Scoliotic Cells
  JOURNAL   Genes (Basel) 14 (5), 1111 (2023)
   PUBMED   37239471
  REMARK    GeneRIF: Differential Regulation of POC5 by ERalpha in Human Normal
            and Scoliotic Cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2185)
  AUTHORS   O'Neill,A.C., Uzbas,F., Antognolli,G., Merino,F., Draganova,K.,
            Jack,A., Zhang,S., Pedini,G., Schessner,J.P., Cramer,K.,
            Schepers,A., Metzger,F., Esgleas,M., Smialowski,P., Guerrini,R.,
            Falk,S., Feederle,R., Freytag,S., Wang,Z., Bahlo,M., Jungmann,R.,
            Bagni,C., Borner,G.H.H., Robertson,S.P., Hauck,S.M. and Gotz,M.
  TITLE     Spatial centrosome proteome of human neural cells uncovers
            disease-relevant heterogeneity
  JOURNAL   Science 376 (6599), eabf9088 (2022)
   PUBMED   35709258
REFERENCE   4  (bases 1 to 2185)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   5  (bases 1 to 2185)
  AUTHORS   Mathieu,H., Spataru,A., Aragon-Martin,J.A., Child,A., Barchi,S.,
            Fortin,C., Parent,S. and Moldovan,F.
  TITLE     Prevalence of POC5 Coding Variants in French-Canadian and British
            AIS Cohort
  JOURNAL   Genes (Basel) 12 (7), 1032 (2021)
   PUBMED   34356048
  REMARK    GeneRIF: Prevalence of POC5 Coding Variants in French-Canadian and
            British AIS Cohort.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2185)
  AUTHORS   Berndt,S.I., Gustafsson,S., Magi,R., Ganna,A., Wheeler,E.,
            Feitosa,M.F., Justice,A.E., Monda,K.L., Croteau-Chonka,D.C.,
            Day,F.R., Esko,T., Fall,T., Ferreira,T., Gentilini,D.,
            Jackson,A.U., Luan,J., Randall,J.C., Vedantam,S., Willer,C.J.,
            Winkler,T.W., Wood,A.R., Workalemahu,T., Hu,Y.J., Lee,S.H.,
            Liang,L., Lin,D.Y., Min,J.L., Neale,B.M., Thorleifsson,G., Yang,J.,
            Albrecht,E., Amin,N., Bragg-Gresham,J.L., Cadby,G., den Heijer,M.,
            Eklund,N., Fischer,K., Goel,A., Hottenga,J.J., Huffman,J.E.,
            Jarick,I., Johansson,A., Johnson,T., Kanoni,S., Kleber,M.E.,
            Konig,I.R., Kristiansson,K., Kutalik,Z., Lamina,C., Lecoeur,C.,
            Li,G., Mangino,M., McArdle,W.L., Medina-Gomez,C.,
            Muller-Nurasyid,M., Ngwa,J.S., Nolte,I.M., Paternoster,L.,
            Pechlivanis,S., Perola,M., Peters,M.J., Preuss,M., Rose,L.M.,
            Shi,J., Shungin,D., Smith,A.V., Strawbridge,R.J., Surakka,I.,
            Teumer,A., Trip,M.D., Tyrer,J., Van Vliet-Ostaptchouk,J.V.,
            Vandenput,L., Waite,L.L., Zhao,J.H., Absher,D., Asselbergs,F.W.,
            Atalay,M., Attwood,A.P., Balmforth,A.J., Basart,H., Beilby,J.,
            Bonnycastle,L.L., Brambilla,P., Bruinenberg,M., Campbell,H.,
            Chasman,D.I., Chines,P.S., Collins,F.S., Connell,J.M.,
            Cookson,W.O., de Faire,U., de Vegt,F., Dei,M., Dimitriou,M.,
            Edkins,S., Estrada,K., Evans,D.M., Farrall,M., Ferrario,M.M.,
            Ferrieres,J., Franke,L., Frau,F., Gejman,P.V., Grallert,H.,
            Gronberg,H., Gudnason,V., Hall,A.S., Hall,P., Hartikainen,A.L.,
            Hayward,C., Heard-Costa,N.L., Heath,A.C., Hebebrand,J., Homuth,G.,
            Hu,F.B., Hunt,S.E., Hypponen,E., Iribarren,C., Jacobs,K.B.,
            Jansson,J.O., Jula,A., Kahonen,M., Kathiresan,S., Kee,F.,
            Khaw,K.T., Kivimaki,M., Koenig,W., Kraja,A.T., Kumari,M.,
            Kuulasmaa,K., Kuusisto,J., Laitinen,J.H., Lakka,T.A.,
            Langenberg,C., Launer,L.J., Lind,L., Lindstrom,J., Liu,J.,
            Liuzzi,A., Lokki,M.L., Lorentzon,M., Madden,P.A., Magnusson,P.K.,
            Manunta,P., Marek,D., Marz,W., Mateo Leach,I., McKnight,B.,
            Medland,S.E., Mihailov,E., Milani,L., Montgomery,G.W., Mooser,V.,
            Muhleisen,T.W., Munroe,P.B., Musk,A.W., Narisu,N., Navis,G.,
            Nicholson,G., Nohr,E.A., Ong,K.K., Oostra,B.A., Palmer,C.N.,
            Palotie,A., Peden,J.F., Pedersen,N., Peters,A., Polasek,O.,
            Pouta,A., Pramstaller,P.P., Prokopenko,I., Putter,C.,
            Radhakrishnan,A., Raitakari,O., Rendon,A., Rivadeneira,F.,
            Rudan,I., Saaristo,T.E., Sambrook,J.G., Sanders,A.R., Sanna,S.,
            Saramies,J., Schipf,S., Schreiber,S., Schunkert,H., Shin,S.Y.,
            Signorini,S., Sinisalo,J., Skrobek,B., Soranzo,N., Stancakova,A.,
            Stark,K., Stephens,J.C., Stirrups,K., Stolk,R.P., Stumvoll,M.,
            Swift,A.J., Theodoraki,E.V., Thorand,B., Tregouet,D.A., Tremoli,E.,
            Van der Klauw,M.M., van Meurs,J.B., Vermeulen,S.H., Viikari,J.,
            Virtamo,J., Vitart,V., Waeber,G., Wang,Z., Widen,E., Wild,S.H.,
            Willemsen,G., Winkelmann,B.R., Witteman,J.C., Wolffenbuttel,B.H.,
            Wong,A., Wright,A.F., Zillikens,M.C., Amouyel,P., Boehm,B.O.,
            Boerwinkle,E., Boomsma,D.I., Caulfield,M.J., Chanock,S.J.,
            Cupples,L.A., Cusi,D., Dedoussis,G.V., Erdmann,J., Eriksson,J.G.,
            Franks,P.W., Froguel,P., Gieger,C., Gyllensten,U., Hamsten,A.,
            Harris,T.B., Hengstenberg,C., Hicks,A.A., Hingorani,A., Hinney,A.,
            Hofman,A., Hovingh,K.G., Hveem,K., Illig,T., Jarvelin,M.R.,
            Jockel,K.H., Keinanen-Kiukaanniemi,S.M., Kiemeney,L.A., Kuh,D.,
            Laakso,M., Lehtimaki,T., Levinson,D.F., Martin,N.G., Metspalu,A.,
            Morris,A.D., Nieminen,M.S., Njolstad,I., Ohlsson,C.,
            Oldehinkel,A.J., Ouwehand,W.H., Palmer,L.J., Penninx,B., Power,C.,
            Province,M.A., Psaty,B.M., Qi,L., Rauramaa,R., Ridker,P.M.,
            Ripatti,S., Salomaa,V., Samani,N.J., Snieder,H., Sorensen,T.I.,
            Spector,T.D., Stefansson,K., Tonjes,A., Tuomilehto,J.,
            Uitterlinden,A.G., Uusitupa,M., van der Harst,P., Vollenweider,P.,
            Wallaschofski,H., Wareham,N.J., Watkins,H., Wichmann,H.E.,
            Wilson,J.F., Abecasis,G.R., Assimes,T.L., Barroso,I., Boehnke,M.,
            Borecki,I.B., Deloukas,P., Fox,C.S., Frayling,T., Groop,L.C.,
            Haritunian,T., Heid,I.M., Hunter,D., Kaplan,R.C., Karpe,F.,
            Moffatt,M.F., Mohlke,K.L., O'Connell,J.R., Pawitan,Y., Schadt,E.E.,
            Schlessinger,D., Steinthorsdottir,V., Strachan,D.P.,
            Thorsteinsdottir,U., van Duijn,C.M., Visscher,P.M., Di Blasio,A.M.,
            Hirschhorn,J.N., Lindgren,C.M., Morris,A.P., Meyre,D., Scherag,A.,
            McCarthy,M.I., Speliotes,E.K., North,K.E., Loos,R.J. and
            Ingelsson,E.
  TITLE     Genome-wide meta-analysis identifies 11 new loci for anthropometric
            traits and provides insights into genetic architecture
  JOURNAL   Nat Genet 45 (5), 501-512 (2013)
   PUBMED   23563607
REFERENCE   7  (bases 1 to 2185)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   8  (bases 1 to 2185)
  AUTHORS   Speliotes,E.K., Willer,C.J., Berndt,S.I., Monda,K.L.,
            Thorleifsson,G., Jackson,A.U., Lango Allen,H., Lindgren,C.M.,
            Luan,J., Magi,R., Randall,J.C., Vedantam,S., Winkler,T.W., Qi,L.,
            Workalemahu,T., Heid,I.M., Steinthorsdottir,V., Stringham,H.M.,
            Weedon,M.N., Wheeler,E., Wood,A.R., Ferreira,T., Weyant,R.J.,
            Segre,A.V., Estrada,K., Liang,L., Nemesh,J., Park,J.H.,
            Gustafsson,S., Kilpelainen,T.O., Yang,J., Bouatia-Naji,N., Esko,T.,
            Feitosa,M.F., Kutalik,Z., Mangino,M., Raychaudhuri,S., Scherag,A.,
            Smith,A.V., Welch,R., Zhao,J.H., Aben,K.K., Absher,D.M., Amin,N.,
            Dixon,A.L., Fisher,E., Glazer,N.L., Goddard,M.E., Heard-Costa,N.L.,
            Hoesel,V., Hottenga,J.J., Johansson,A., Johnson,T., Ketkar,S.,
            Lamina,C., Li,S., Moffatt,M.F., Myers,R.H., Narisu,N., Perry,J.R.,
            Peters,M.J., Preuss,M., Ripatti,S., Rivadeneira,F., Sandholt,C.,
            Scott,L.J., Timpson,N.J., Tyrer,J.P., van Wingerden,S.,
            Watanabe,R.M., White,C.C., Wiklund,F., Barlassina,C., Chasman,D.I.,
            Cooper,M.N., Jansson,J.O., Lawrence,R.W., Pellikka,N.,
            Prokopenko,I., Shi,J., Thiering,E., Alavere,H., Alibrandi,M.T.,
            Almgren,P., Arnold,A.M., Aspelund,T., Atwood,L.D., Balkau,B.,
            Balmforth,A.J., Bennett,A.J., Ben-Shlomo,Y., Bergman,R.N.,
            Bergmann,S., Biebermann,H., Blakemore,A.I., Boes,T.,
            Bonnycastle,L.L., Bornstein,S.R., Brown,M.J., Buchanan,T.A.,
            Busonero,F., Campbell,H., Cappuccio,F.P., Cavalcanti-Proenca,C.,
            Chen,Y.D., Chen,C.M., Chines,P.S., Clarke,R., Coin,L., Connell,J.,
            Day,I.N., den Heijer,M., Duan,J., Ebrahim,S., Elliott,P.,
            Elosua,R., Eiriksdottir,G., Erdos,M.R., Eriksson,J.G.,
            Facheris,M.F., Felix,S.B., Fischer-Posovszky,P., Folsom,A.R.,
            Friedrich,N., Freimer,N.B., Fu,M., Gaget,S., Gejman,P.V.,
            Geus,E.J., Gieger,C., Gjesing,A.P., Goel,A., Goyette,P.,
            Grallert,H., Grassler,J., Greenawalt,D.M., Groves,C.J.,
            Gudnason,V., Guiducci,C., Hartikainen,A.L., Hassanali,N.,
            Hall,A.S., Havulinna,A.S., Hayward,C., Heath,A.C., Hengstenberg,C.,
            Hicks,A.A., Hinney,A., Hofman,A., Homuth,G., Hui,J., Igl,W.,
            Iribarren,C., Isomaa,B., Jacobs,K.B., Jarick,I., Jewell,E.,
            John,U., Jorgensen,T., Jousilahti,P., Jula,A., Kaakinen,M.,
            Kajantie,E., Kaplan,L.M., Kathiresan,S., Kettunen,J., Kinnunen,L.,
            Knowles,J.W., Kolcic,I., Konig,I.R., Koskinen,S., Kovacs,P.,
            Kuusisto,J., Kraft,P., Kvaloy,K., Laitinen,J., Lantieri,O.,
            Lanzani,C., Launer,L.J., Lecoeur,C., Lehtimaki,T., Lettre,G.,
            Liu,J., Lokki,M.L., Lorentzon,M., Luben,R.N., Ludwig,B.,
            Manunta,P., Marek,D., Marre,M., Martin,N.G., McArdle,W.L.,
            McCarthy,A., McKnight,B., Meitinger,T., Melander,O., Meyre,D.,
            Midthjell,K., Montgomery,G.W., Morken,M.A., Morris,A.P., Mulic,R.,
            Ngwa,J.S., Nelis,M., Neville,M.J., Nyholt,D.R., O'Donnell,C.J.,
            O'Rahilly,S., Ong,K.K., Oostra,B., Pare,G., Parker,A.N., Perola,M.,
            Pichler,I., Pietilainen,K.H., Platou,C.G., Polasek,O., Pouta,A.,
            Rafelt,S., Raitakari,O., Rayner,N.W., Ridderstrale,M., Rief,W.,
            Ruokonen,A., Robertson,N.R., Rzehak,P., Salomaa,V., Sanders,A.R.,
            Sandhu,M.S., Sanna,S., Saramies,J., Savolainen,M.J., Scherag,S.,
            Schipf,S., Schreiber,S., Schunkert,H., Silander,K., Sinisalo,J.,
            Siscovick,D.S., Smit,J.H., Soranzo,N., Sovio,U., Stephens,J.,
            Surakka,I., Swift,A.J., Tammesoo,M.L., Tardif,J.C.,
            Teder-Laving,M., Teslovich,T.M., Thompson,J.R., Thomson,B.,
            Tonjes,A., Tuomi,T., van Meurs,J.B., van Ommen,G.J., Vatin,V.,
            Viikari,J., Visvikis-Siest,S., Vitart,V., Vogel,C.I., Voight,B.F.,
            Waite,L.L., Wallaschofski,H., Walters,G.B., Widen,E., Wiegand,S.,
            Wild,S.H., Willemsen,G., Witte,D.R., Witteman,J.C., Xu,J.,
            Zhang,Q., Zgaga,L., Ziegler,A., Zitting,P., Beilby,J.P.,
            Farooqi,I.S., Hebebrand,J., Huikuri,H.V., James,A.L., Kahonen,M.,
            Levinson,D.F., Macciardi,F., Nieminen,M.S., Ohlsson,C.,
            Palmer,L.J., Ridker,P.M., Stumvoll,M., Beckmann,J.S., Boeing,H.,
            Boerwinkle,E., Boomsma,D.I., Caulfield,M.J., Chanock,S.J.,
            Collins,F.S., Cupples,L.A., Smith,G.D., Erdmann,J., Froguel,P.,
            Gronberg,H., Gyllensten,U., Hall,P., Hansen,T., Harris,T.B.,
            Hattersley,A.T., Hayes,R.B., Heinrich,J., Hu,F.B., Hveem,K.,
            Illig,T., Jarvelin,M.R., Kaprio,J., Karpe,F., Khaw,K.T.,
            Kiemeney,L.A., Krude,H., Laakso,M., Lawlor,D.A., Metspalu,A.,
            Munroe,P.B., Ouwehand,W.H., Pedersen,O., Penninx,B.W., Peters,A.,
            Pramstaller,P.P., Quertermous,T., Reinehr,T., Rissanen,A.,
            Rudan,I., Samani,N.J., Schwarz,P.E., Shuldiner,A.R., Spector,T.D.,
            Tuomilehto,J., Uda,M., Uitterlinden,A., Valle,T.T., Wabitsch,M.,
            Waeber,G., Wareham,N.J., Watkins,H., Wilson,J.F., Wright,A.F.,
            Zillikens,M.C., Chatterjee,N., McCarroll,S.A., Purcell,S.,
            Schadt,E.E., Visscher,P.M., Assimes,T.L., Borecki,I.B.,
            Deloukas,P., Fox,C.S., Groop,L.C., Haritunians,T., Hunter,D.J.,
            Kaplan,R.C., Mohlke,K.L., O'Connell,J.R., Peltonen,L.,
            Schlessinger,D., Strachan,D.P., van Duijn,C.M., Wichmann,H.E.,
            Frayling,T.M., Thorsteinsdottir,U., Abecasis,G.R., Barroso,I.,
            Boehnke,M., Stefansson,K., North,K.E., McCarthy,M.I.,
            Hirschhorn,J.N., Ingelsson,E. and Loos,R.J.
  CONSRTM   MAGIC; Procardis Consortium
  TITLE     Association analyses of 249,796 individuals reveal 18 new loci
            associated with body mass index
  JOURNAL   Nat Genet 42 (11), 937-948 (2010)
   PUBMED   20935630
REFERENCE   9  (bases 1 to 2185)
  AUTHORS   Azimzadeh,J., Hergert,P., Delouvee,A., Euteneuer,U.,
            Formstecher,E., Khodjakov,A. and Bornens,M.
  TITLE     hPOC5 is a centrin-binding protein required for assembly of
            full-length centrioles
  JOURNAL   J Cell Biol 185 (1), 101-114 (2009)
   PUBMED   19349582
  REMARK    GeneRIF: hPOC5, a conserved centrin-binding protein that contains
            Sfi1p-like repeats is characterized.
REFERENCE   10 (bases 1 to 2185)
  AUTHORS   Brill,L.M., Salomon,A.R., Ficarro,S.B., Mukherji,M.,
            Stettler-Gill,M. and Peters,E.C.
  TITLE     Robust phosphoproteomic profiling of tyrosine phosphorylation sites
            from human T cells using immobilized metal affinity chromatography
            and tandem mass spectrometry
  JOURNAL   Anal Chem 76 (10), 2763-2772 (2004)
   PUBMED   15144186
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BJ991592.1, BC010695.1, CA441610.1 and AC010245.4.
            
            On May 17, 2019 this sequence version replaced NM_001099271.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.123748.1,
                                           SRR1803614.210724.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000428202.7/ ENSP00000410216.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                BJ991592.1         52-87
            37-804              BC010695.1         1-768
            805-2107            BC010695.1         770-2072
            2108-2111           CA441610.1         9-12                c
            2112-2185           AC010245.4         108374-108447       c
FEATURES             Location/Qualifiers
     source          1..2185
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q13.3"
     gene            1..2185
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /note="POC5 centriolar protein"
                     /db_xref="GeneID:134359"
                     /db_xref="HGNC:HGNC:26658"
                     /db_xref="MIM:617880"
     exon            1..132
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            133..230
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..1874
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /note="isoform 1 is encoded by transcript variant 1;
                     centrosomal protein POC5; proteome of centriole 5; hPOC5;
                     protein of centriole 5; POC5 centriolar protein homolog"
                     /codon_start=1
                     /product="centrosomal protein POC5 isoform 1"
                     /protein_id="NP_001092741.1"
                     /db_xref="CCDS:CCDS47236.1"
                     /db_xref="GeneID:134359"
                     /db_xref="HGNC:HGNC:26658"
                     /db_xref="MIM:617880"
                     /translation="MSSDEEKYSLPVVQNDSSRGSSVSSNLQEEYEELLHYAIVTPNI
                     EPCASQSSHPKGELVPDVRISTIHDILHSQGNNSEVRETAIEVGKGCDFHISSHSKTD
                     ESSPVLSPRKPSHPVMDFFSSHLLADSSSPATNSSHTDAHEILVSDFLVSDENLQKME
                     NVLDLWSSGLKTNIISELSKWRLNFIDWHRMEMRKEKEKHAAHLKQLCNQINELKELQ
                     KTFEISIGRKDEVISSLSHAIGKQKEKIELMRTFFHWRIGHVRARQDVYEGKLADQYY
                     QRTLLKKVWKVWRSVVQKQWKDVVERACQARAEEVCIQISNDYEAKVAMLSGALENAK
                     AEIQRMQHEKEHFEDSMKKAFMRGVCALNLEAMTIFQNRNDAGIDSTNNKKEEYGPGV
                     QGKEHSAHLDPSAPPMPLPVTSPLLPSPPAAVGGASATAVPSAASMTSTRAASASSVH
                     VPVSALGAGSAATAASEEMYVPRVVTSAQQKAGRTITARITGRCDFASKNRISSSLAI
                     MGVSPPMSSVVVEKHHPVTVQTIPQATAAKYPRTIHPESSTSASRSLGTRSAHTQSLT
                     SVHSIKVVD"
     exon            231..369
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            370..453
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            454..659
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            660..836
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            837..941
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1121
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1275
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1553
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..1730
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     exon            1731..2185
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2083..2088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /note="hexamer: AGTAAA"
     regulatory      2099..2104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /note="hexamer: ATTAAA"
     polyA_site      2107
                     /gene="POC5"
                     /gene_synonym="C5orf37"
                     /note="major polyA site"
     polyA_site      2121
                     /gene="POC5"
                     /gene_synonym="C5orf37"
ORIGIN      
        1 gcagtttgaa actgtcaggt tgccgtctag gtagcggttg tgcttgctga ggctgcactt
       61 gctgacactg cagctgcgac gcggctaaga ggcgcagagc gaggagtcgg gatttggtcg
      121 cgagcggcga cgagcatttg tgcagaatgt catcagatga ggagaaatac tcacttccag
      181 ttgtgcaaaa tgactccagt cgaggcagtt ctgtctcttc gaatcttcag gaagaatatg
      241 aagaactgct tcattatgct atagtgactc caaatattga accctgtgct tcacagtcat
      301 ctcatcctaa gggagaattg gtgccagatg tcagaatttc tacaattcat gatattcttc
      361 atagtcaagg aaataactct gaagtaagag aaactgcaat agaagttgga aaaggatgtg
      421 atttccatat ttcaagtcat tcaaagacag atgagtcatc accagtgtta tcgccaagga
      481 agccttctca cccagtcatg gattttttca gttcacatct tttagctgac tcttcctcac
      541 cagcaacaaa ttctagtcat acagatgccc atgaaatact tgtgagcgat tttcttgttt
      601 ctgatgaaaa ccttcagaag atggaaaatg tgcttgatct ttggagttca ggtcttaaga
      661 caaacatcat atctgaacta agtaaatgga gacttaattt tattgactgg caccgaatgg
      721 aaatgagaaa agagaaagaa aaacatgcag cacatttaaa acaactgtgt aatcagatca
      781 atgaattgaa ggagctgcaa aaaacctttg aaatctccat tgggagaaaa gatgaggtga
      841 tttctagctt gtctcatgcc ataggcaagc aaaaggaaaa gatagagttg atgagaacat
      901 tcttccactg gcgaatcggc catgtcagag ccagacagga tgtttatgaa ggtaaactag
      961 ctgaccagta ctaccagaga actttactga agaaagtctg gaaagtctgg cgttccgtag
     1021 tgcaaaagca gtggaaagat gtggtagaaa gagcttgtca agcaagagct gaagaagttt
     1081 gtatccagat ttccaatgat tatgaagcca aagttgctat gttatctgga gctttggaaa
     1141 atgcaaaagc tgagattcaa agaatgcaac atgaaaaaga gcactttgaa gattccatga
     1201 aaaaagcttt catgaggggt gtatgtgcat taaatcttga agccatgact atatttcaaa
     1261 acagaaatga tgcagggata gactccacaa ataataaaaa ggaagagtat ggtcctggtg
     1321 ttcaaggaaa agaacattct gctcatttgg atccttcagc tcctccgatg cccttaccag
     1381 ttacatcacc actgctgcca tccccaccag ccgccgtcgg aggagccagc gcgactgccg
     1441 ttccctcagc tgcttcgatg acttctacca gggctgcttc cgcatcttct gttcacgttc
     1501 ctgtttctgc tcttggtgca ggatctgcag ctactgctgc atcagaagaa atgtatgtgc
     1561 caagagttgt aacctctgca caacagaaag caggaagaac tattacagcc cggatcacag
     1621 gaagatgtga ttttgcttca aaaaatagaa ttagcagcag tttagctata atgggagttt
     1681 ctcctcccat gagctcagtt gttgtggaaa aacatcatcc agtcacagtg caaaccattc
     1741 ctcaagcaac tgcagcaaaa tatccccgga ccattcatcc tgaaagtagt acctcagctt
     1801 ccagatcact tggaaccaga tcagctcaca cccagtctct cacaagtgtt cattccataa
     1861 aagtggttga ctaaagtgaa tatgtccata gtggggtctt ttaatccctc tggtcttacc
     1921 aagggttaga agtcttttgg ttttaacttt tccatattgt tagaacatca tggagacatc
     1981 atgttcatct gttcaaaatt acaagaggct ttttcaagct ctaccatgct ttgtaactat
     2041 atgtagaaat tattttaatg ttatttttta tttaagcaat taagtaaaac ttttttaaat
     2101 taaaaaagaa actggacttt atttctttaa tatgtttagc ctgttgctga ttacagcatc
     2161 aaaatatata aatttatttt cacta
//
