LOCUS       XM_047444777            2641 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens PMS1 homolog 1, mismatch repair system
            component (PMS1), transcript variant X7, mRNA.
ACCESSION   XM_047444777
VERSION     XM_047444777.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2641
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..2641
                     /gene="PMS1"
                     /gene_synonym="HNPCC3; hPMS1; MLH2; PMSL1"
                     /note="PMS1 homolog 1, mismatch repair system component;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 4 mRNAs, 29 ESTs, 296 long SRA reads, 8
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 27 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:5378"
                     /db_xref="HGNC:HGNC:9121"
                     /db_xref="MIM:600258"
     CDS             136..2448
                     /gene="PMS1"
                     /gene_synonym="HNPCC3; hPMS1; MLH2; PMSL1"
                     /codon_start=1
                     /product="PMS1 protein homolog 1 isoform X4"
                     /protein_id="XP_047300733.1"
                     /db_xref="GeneID:5378"
                     /db_xref="HGNC:HGNC:9121"
                     /db_xref="MIM:600258"
                     /translation="MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKL
                     ENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICC
                     IAEVLITTRTAADNFSTQYVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYS
                     TAKKCKDEIKKIQDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAV
                     MNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLI
                     RHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIALENLMT
                     TCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTSVIPFQN
                     DMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSWENSQ
                     TEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKNSV
                     GENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
                     SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLNLFNGS
                     HYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPF
                     YGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIY
                     RMKHQFGNEIKECVHGRPFFHHLTYLPETT"
ORIGIN      
        1 agtgccgcgc tctctgcacc cgctctgccg cgcgcgtgcg tgctgggtgc gggtgcgggt
       61 gcggggttgg gcctgcgcat cgggtgagac gctggctgct tgcggctagt ggatgctgct
      121 ctgttaaaag cgaaaatgaa acaattgcct gcggcaacag ttcgactcct ttcaagttct
      181 cagatcatca cttcggtggt cagtgttgta aaagagctta ttgaaaactc cttggatgct
      241 ggtgccacaa gcgtagatgt taaactggag aactatggat ttgataaaat tgaggtgcga
      301 gataacgggg agggtatcaa ggctgttgat gcacctgtaa tggcaatgaa gtactacacc
      361 tcaaaaataa atagtcatga agatcttgaa aatttgacaa cttacggttt tcgtggagaa
      421 gccttggggt caatttgttg tatagctgag gttttaatta caacaagaac ggctgctgat
      481 aattttagca cccagtatgt tttagatggc agtggccaca tactttctca gaaaccttca
      541 catcttggtc aaggtacaac tgtaactgct ttaagattat ttaagaatct acctgtaaga
      601 aagcagtttt actcaactgc aaaaaaatgt aaagatgaaa taaaaaagat ccaagatctc
      661 ctcatgagct ttggtatcct taaacctgac ttaaggattg tctttgtaca taacaaggca
      721 gttatttggc agaaaagcag agtatcagat cacaagatgg ctctcatgtc agttctgggg
      781 actgctgtta tgaacaatat ggaatccttt cagtaccact ctgaagaatc tcagatttat
      841 ctcagtggat ttcttccaaa gtgtgatgca gaccactctt tcactagtct ttcaacacca
      901 gaaagaagtt tcatcttcat aaacagtcga ccagtacatc aaaaagatat cttaaagtta
      961 atccgacatc attacaatct gaaatgccta aaggaatcta ctcgtttgta tcctgttttc
     1021 tttctgaaaa tcgatgttcc tacagctgat gttgatgtaa atttaacacc agataaaagc
     1081 caagtattat tacaaaataa ggaatctgtt ttaattgctc ttgaaaatct gatgacgact
     1141 tgttatggac cattacctag tacaaattct tatgaaaata ataaaacaga tgtttccgca
     1201 gctgacatcg ttcttagtaa aacagcagaa acagatgtgc tttttaataa agtggaatca
     1261 tctggaaaga attattcaaa tgttgatact tcagtcattc cattccaaaa tgatatgcat
     1321 aatgatgaat ctggaaaaaa cactgatgat tgtttaaatc accagataag tattggtgac
     1381 tttggttatg gtcattgtag tagtgaaatt tctaacattg ataaaaacac taagaatgca
     1441 tttcaggaca tttcaatgag taatgtatca tgggagaact ctcagacgga atatagtaaa
     1501 acttgtttta taagttccgt taagcacacc cagtcagaaa atggcaataa agaccatata
     1561 gatgagagtg gggaaaatga ggaagaagca ggtcttgaaa actcttcgga aatttctgca
     1621 gatgagtgga gcaggggaaa tatacttaaa aattcagtgg gagagaatat tgaacctgtg
     1681 aaaattttag tgcctgaaaa aagtttacca tgtaaagtaa gtaataataa ttatccaatc
     1741 cctgaacaaa tgaatcttaa tgaagattca tgtaacaaaa aatcaaatgt aatagataat
     1801 aaatctggaa aagttacagc ttatgattta cttagcaatc gagtaatcaa gaaacccatg
     1861 tcagcaagtg ctctttttgt tcaagatcat cgtcctcagt ttctcataga aaatcctaag
     1921 actagtttag aggatgcaac actacaaatt gaagaactgt ggaagacatt gagtgaagag
     1981 gaaaaactga atctttttaa tggatctcat tatttagacg ttttatataa aatgacagca
     2041 gatgaccaaa gatacagtgg atcaacttac ctgtctgatc ctcgtcttac agcgaatggt
     2101 ttcaagataa aattgatacc aggagtttca attactgaaa attacttgga aatagaagga
     2161 atggctaatt gtctcccatt ctatggagta gcagatttaa aagaaattct taatgctata
     2221 ttaaacagaa atgcaaagga agtttatgaa tgtagacctc gcaaagtgat aagttattta
     2281 gagggagaag cagtgcgtct atccagacaa ttacccatgt acttatcaaa agaggacatc
     2341 caagacatta tctacagaat gaagcaccag tttggaaatg aaattaaaga gtgtgttcat
     2401 ggtcgcccat tttttcatca tttaacctat cttccagaaa ctacatgatt aaatatgttt
     2461 aagaagatta gttaccattg aaattggttc tgtcataaaa cagcatgagt ctggttttaa
     2521 attatctttg tattatgtgt cacatggtta ttttttaaat gaggattcac tgacttgttt
     2581 ttatattgaa aaaagttcca cgtattgtag aaaacgtaaa taaactaata tagactattc
     2641 a
//
