LOCUS       XM_005273165            7214 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens plexin A2 (PLXNA2), transcript variant X2,
            mRNA.
ACCESSION   XM_005273165
VERSION     XM_005273165.5
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005273165.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7214
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..7214
                     /gene="PLXNA2"
                     /gene_synonym="OCT; PLXN2"
                     /note="plexin A2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 22 ESTs, 161 long SRA
                     reads, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 13 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:5362"
                     /db_xref="HGNC:HGNC:9100"
                     /db_xref="MIM:601054"
     CDS             778..6249
                     /gene="PLXNA2"
                     /gene_synonym="OCT; PLXN2"
                     /codon_start=1
                     /product="plexin-A2 isoform X2"
                     /protein_id="XP_005273222.1"
                     /db_xref="GeneID:5362"
                     /db_xref="HGNC:HGNC:9100"
                     /db_xref="MIM:601054"
                     /translation="MSTHRSRLLTAAPLSMEQRRPWPRALEVDSRSVVLLSVVWVLLA
                     PPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGP
                     EEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDL
                     FILVEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKL
                     PRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPE
                     TPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPG
                     DSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQG
                     EGNLELNWLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSV
                     ASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQR
                     YLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNR
                     FAASISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLTEVEGQVSGS
                     QVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVN
                     SAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPITLKAR
                     NLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAV
                     VWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSP
                     SSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGV
                     PCTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVL
                     SLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGL
                     GPVPVSVSVDRAHVDSNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPR
                     IRVKFNGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLI
                     YNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETP
                     CAVTVSETQLLCEPPNLTGQHKVMVHVGGMVFSPGSVSVISDSLLTLPAIVSIAAGGS
                     LLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINELTS
                     DLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKLFAQLINNKV
                     FLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKN
                     HPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITG
                     EARYSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKVLNCDTITQVKEKILDAVY
                     KNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVV
                     ALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLESGVKVWH
                     LVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKTLLVLLCSCQEAPSPPACSSDTVSGL
                     ACSLCPLIHPWEARTRGTSCLPVKDPEPTPCVECGMWLQGTLQKFVDDLFETLFSTVH
                     RGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNWL"
     polyA_site      7214
                     /gene="PLXNA2"
                     /gene_synonym="OCT; PLXN2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gataatgagc tgcatggtga aatagggagg ccggcgctca gggctcctcc gccgccgccg
       61 ccgccgccgc cgccgccgcc accgcgggag ccagagctgc cgggaggagc ggcatccgcg
      121 ccagactgga gcgggagggc ggcggagggc agttgctggg aatttttcag ccgagagggc
      181 gagcgatccg gagagagacc ccgagagctt gggagcggta gggcgtgcga gcgccgcagc
      241 cagcggagca aacctcgaaa tagatctgga aagccaggct cccggaggaa atgggactgt
      301 gaacgaaccg gagagcaaga agggaaggaa gcgccgggat tgctgatgtc agaggagccc
      361 ggaaagtcgc gctggaaaaa tctgaagaca gccggggctc tgcttcttcc tcaggagaga
      421 caccgccggc cgcccccaca cgccccctcg gcgcctccgg gtgccccctg agagccggcg
      481 acagcgccca gccgggctgc tgcggggcga cggaggactg aggggcgcgc ggagcggaga
      541 ccgaggagcg acttcaggaa tacagataag tgtctggtgg cttgacgtgg attttaatga
      601 atttggactc catgtggatt tggtcgtctc cctgattccg agctgcgggc agggagaggg
      661 gcctcgcgcc gccctcagca gccggcggcg gccgaggtag accgagcggg gacggaagga
      721 cagaccgacg tcgccgagct ggaatcatgt gagggccaac cggggaaggt ggagcagatg
      781 agcacacaca ggagccgtct cctcaccgcc gcccctctca gcatggaaca gaggcggccc
      841 tggccccggg ccctggaggt ggacagccgc tctgtggtcc tgctctcagt ggtctgggtg
      901 ctgctggccc ccccagcagc cggcatgcct cagttcagca ccttccactc tgagaatcgt
      961 gactggacct tcaaccactt gaccgtccac caagggacgg gggccgtcta tgtgggggcc
     1021 atcaaccggg tctataagct gacaggcaac ctgaccatcc aggtggctca taagacaggg
     1081 ccagaagagg acaacaagtc ttgttacccg cccctcatcg tgcagccctg cagcgaagtg
     1141 ctcaccctca ccaacaatgt caacaagctg ctcatcattg actactctga gaaccgcctg
     1201 ctggcctgtg ggagcctcta ccagggggtc tgcaagctgc tgcggctgga tgacctcttc
     1261 atcctggtgg agccatccca caagaaggag cactacctgt ccagtgtcaa caagacgggc
     1321 accatgtacg gggtgattgt gcgctctgag ggtgaggatg gcaagctctt catcggcacg
     1381 gctgtggatg ggaagcagga ttacttcccg accctgtcca gccggaagct gccccgagac
     1441 cctgagtcct cagccatgct cgactatgag ctacacagcg attttgtctc ctctctcatc
     1501 aagatccctt cagacaccct ggccctggtc tcccactttg acatcttcta catctacggc
     1561 tttgctagtg ggggctttgt ctactttctc actgtccagc ccgagacccc tgagggtgtg
     1621 gccatcaact ccgctggaga cctcttctac acctcacgca tcgtgcggct ctgcaaggat
     1681 gaccccaagt tccactcata cgtgtccctg cccttcggct gcacccgggc cggggtggaa
     1741 taccgcctcc tgcaggctgc ttacctggcc aagcctgggg actcactggc ccaggccttc
     1801 aatatcacca gccaggacga tgtactcttt gccatcttct ccaaagggca gaagcagtat
     1861 caccacccgc ccgatgactc tgccctgtgt gccttcccta tccgggccat caacttgcag
     1921 atcaaggagc gcctgcagtc ctgctaccag ggcgagggca acctggagct caactggctg
     1981 ctggggaagg acgtccagtg caccaaggcg cctgtcccca tcgatgataa cttctgtgga
     2041 ctggacatca accagcccct gggaggctca actccagtgg agggcctgac cctgtacacc
     2101 accagcaggg accgcatgac ctctgtggcc tcctacgttt acaacggcta cagcgtggtt
     2161 tttgtgggga ctaagagtgg caagctgaaa aagattcggg ccgacggtcc cccccatggt
     2221 ggggtccagt acgagatggt ctctgtgctc aaggacggaa gccccatcct ccgggacatg
     2281 gccttctcca ttgatcagcg ctacctgtac gtcatgtctg agagacaggt caccagggtc
     2341 cccgtggagt catgtgagca gtatacgact tgtggggagt gcctgagctc tggggaccct
     2401 cactgtggct ggtgtgccct gcacaacatg tgctcccgca gggacaaatg ccaacaggcc
     2461 tgggaaccta atcgatttgc tgccagcatc agccagtgtg tgagccttgc agtgcatccc
     2521 agcagcatct cagtatctga gcacagccgg ttgcttagcc tggtagtgag tgatgctcct
     2581 gatctatctg cgggtatcgc ctgtgccttt gggaacctga cagaggtgga ggggcaggtg
     2641 tccgggagcc aggtcatctg catctcacct gggcccaagg atgtccctgt catcccgctg
     2701 gatcaagact ggtttgggct ggagctacag ctgaggtcca aggagacagg gaagatattt
     2761 gtcagcaccg agttcaagtt ttacaactgc agtgcccacc aactgtgcct gtcctgtgtc
     2821 aacagcgcct tccgctgcca ttggtgcaag taccgcaacc tctgcactca tgaccccacc
     2881 acctgctcct tccaggaggg ccggatcaat atttcagagg actgtcccca gctggtgccc
     2941 acagaggaga tcttgattcc agtcggggag gtaaagccaa tcacccttaa ggcgcgaaat
     3001 ctgccccagc cgcagtccgg ccagcgaggc tatgagtgtg tcctcaacat acaaggagcc
     3061 atccaccggg tccccgctct gcgcttcaac agctccagcg ttcagtgtca gaacagctcg
     3121 taccagtatg atggcatgga catcagcaat ctggccgtgg atttcgctgt ggtgtggaac
     3181 ggcaatttca tcattgacaa ccctcaggac ctgaaagtcc atctctacaa gtgtgcagcc
     3241 cagcgggaga gctgcggcct ctgcctcaag gccgaccgga agtttgagtg tggctggtgc
     3301 agcggcgagc gcaggtgcac cctccaccag cactgtacca gcccttccag cccctggctc
     3361 gactggtcca gccacaatgt caagtgctcc aaccctcaaa tcaccgagat tttgacggtg
     3421 tctggaccgc cggaaggagg gacgcgagtg accatccatg gcgtgaacct gggtctggac
     3481 ttctccgaga tcgcccacca tgtgcaggtg gctggggtgc cctgcacgcc cctcccaggg
     3541 gaatacatca tcgctgagca gattgtctgt gagatgggcc atgccctcgt gggaaccacc
     3601 tccgggccag tacgcctgtg tattggcgag tgtaagccag agttcatgac gaagtcccat
     3661 cagcagtaca ccttcgtgaa cccttctgtg ctgtcactca acccaatccg aggtcccgag
     3721 tcaggaggca ctatggtgac cattaccggc cattaccttg gggctgggag cagcgtggca
     3781 gtctacctgg gcaaccagac ctgcgagttc tacgggaggt caatgagtga gatcgtgtgt
     3841 gtctcacccc catcatccaa tggccttggc ccggtccctg tttctgtgag tgtcgaccga
     3901 gcccatgtgg atagcaacct gcagtttgag tacatagatg accctcgggt ccagcgcatc
     3961 gagccagagt ggagcattgc cagtggccac acacccctga ccatcacagg cttcaacctg
     4021 gatgtcattc aggagccaag gatccgagtc aaattcaatg gcaaagaatc tgtcaatgtg
     4081 tgtaaagttg tgaacacaac caccctcacc tgcctggcac cctctctgac cacggactac
     4141 cgccctggcc tggacactgt ggaacgccca gatgagtttg gatttgtctt taacaatgtc
     4201 caatccttgc taatttacaa cgacaccaag tttatctact accccaaccc gacctttgaa
     4261 ctgcttagcc ctactggagt cttggatcaa aagccaggat cgcccatcat tctgaagggc
     4321 aaaaacctct gccctcctgc ctctggaggg gccaaactca actacactgt gctcatcgga
     4381 gagacccctt gtgctgtcac cgtatctgag acccagcttc tctgcgagcc tcccaacctc
     4441 accgggcagc acaaggtcat ggttcacgtg ggcgggatgg tgttctcgcc tggctcggtg
     4501 agtgtcatct cagacagctt gctgaccctg ccagccatcg tcagcatcgc ggccggcggc
     4561 agcctcctcc tcatcatcgt catcatcgtc ctcattgcct acaagcgcaa gtctcgagaa
     4621 aatgacctca ctctcaagcg gctgcaaatg cagatggaca atctggagtc ccgtgtggcc
     4681 ttggagtgca aggaagcttt tgctgagctc cagacggata tcaatgagtt gaccagtgac
     4741 ctggaccgct caggaatccc ttacctggac tatcgtacct acgctatgcg agtcctgttc
     4801 ccgggcatcg aggaccaccc cgtcctgcgg gagctggagg tacaaggaaa cgggcagcag
     4861 cacgtggaga aggccctgaa gctctttgcc cagctcatca acaacaaggt gttcctgctg
     4921 accttcatcc gcaccctgga gctgcagcgc agtttctcca tgcgcgaccg gggcaacgtg
     4981 gcttcgctca tcatgaccgg cctgcagggc cgcctggaat atgccactga tgtcctcaag
     5041 cagctgctct ctgacctcat cgataagaac ctggagaaca agaaccaccc caagctgcta
     5101 ctccggagga cagagtctgt ggctgaaaag atgctgacca attggttcgc cttcctcctg
     5161 cacaagttcc taaaggagtg cgcaggggag ccactcttca tgctatactg tgccatcaag
     5221 cagcagatgg agaagggccc cattgatgcc atcacgggcg aggcccgcta ctccctgagc
     5281 gaggacaagc tcatccggca gcagatcgag tacaagaccc tgatcctgaa ctgcgtcaac
     5341 cctgacaacg agaacagtcc agagatccca gtgaaggtgt taaactgtga caccatcaca
     5401 caggtcaagg agaagattct tgatgccgtg tataagaatg tgccctattc ccagcggccg
     5461 agggcagtgg acatggactt ggagtggcgc caaggccgga tcgcccgggt cgtgctgcaa
     5521 gatgaggaca tcaccaccaa gattgagggt gactggaagc ggctcaacac actgatgcat
     5581 tatcaggtgt cagacaggtc ggtggtggct ctggtcccca aacagacctc ctcctacaac
     5641 atccctgcct ctgccagcat ctcccggacg tccatcagca gatacgactc ctccttcagg
     5701 tatacgggca gccccgacag cctgcggtcc cgggccccga tgatcacccc agacctggaa
     5761 agtggggtca aggtgtggca tctggtgaag aaccatgacc acggtgacca gaaggagggt
     5821 gaccggggca gcaagatggt gtccgagatc tacctgaccc ggctactggc caccaagact
     5881 ctcctggtcc tgctgtgctc ctgccaggag gcacccagtc ctccagcttg ttcctcggac
     5941 actgtttccg gactggcttg cagcctgtgc cccctcattc acccatggga agcccggacc
     6001 cggggcactt cctgtcttcc tgtcaaagac cctgagccta caccctgtgt ggaatgtgga
     6061 atgtggctgc agggcaccct gcagaagttt gtggacgact tgtttgagac cttgttcagc
     6121 actgtgcacc ggggcagcgc tctccccctg gccatcaagt acatgtttga tttcctagat
     6181 gagcaggcag acaggcacag catccatgac acagatgtgc ggcacacctg gaaaagcaac
     6241 tggttgtgac cagtacccca agaagagcct cctcccctgg ctctgagatc tctggttctc
     6301 aggagaaggg agctggggga acctatgcaa agagctgcat ttgaagcctg cagcagagct
     6361 tcacagccag acatcgtggg gcattctgag tggggcagtt ctaaggcact tcctgagatg
     6421 gggaatccct gaattaaact gagacgcccg gtgaagttgg tcagcaccgg agagggagtt
     6481 cacacctgct atagacttga gcccactgac agggaggatt tcattgcaaa cttgatctct
     6541 taaggccaag tgattatcct ggcgccatag ctttcaggaa gcagcaggca gaatgccctg
     6601 caggcatgac tctctcccct aaagtcatct ctgcaaccag accagcagtg ggagaagccc
     6661 tcaggcccct ggtatgagac tttatcctca tgggttttga acctggacca cagaccaagc
     6721 taaggactgg ctttcaggtc agacaggacc cggccaagag ctggcatcaa aaggcttcct
     6781 ttgggaaaga gcacagagag gggagagggg aggtccaggc atttgggttg ggcaggcagc
     6841 ccacgcagct gtctggagtt agcggtctcc tcagaaaaca gagccgacac agatgggccc
     6901 aggctgttat ttgggaatca aaagtcctag caaccaacaa aacactttgg aaaaagccaa
     6961 ccccagcccc atctcttcct tcctcctccc gggtcttgtg gtcgctgagc cttcctcagt
     7021 ctgcagcttt gatcacagtg gagtgaaacg aacaggctgg ggtggccctg gggttaagag
     7081 cccacagtcc actttgccag gacaggcctt ccatctgcat tccctggaca gcacatgcct
     7141 gtcccctttg ctttggagca tccccggccc agcgctggga gagggcactt caggggaaat
     7201 caagagaaag tcca
//
