LOCUS       NM_001085420            1100 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens phospholipid scramblase family member 5 (PLSCR5),
            transcript variant 1, mRNA.
ACCESSION   NM_001085420 XM_371670 XM_940910
VERSION     NM_001085420.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1100)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY436642.1 and AC116544.1.
            
            On Aug 11, 2020 this sequence version replaced NM_001085420.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY436642.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA2145743,
                                           SAMEA2148093 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000443512.2/ ENSP00000390111.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-377               AY436642.1         871-1247
            378-378             AC116544.1         55361-55361         c
            379-880             AY436642.1         1249-1750
            881-881             AC116544.1         50915-50915         c
            882-1099            AY436642.1         1752-1969
            1100-1100           AC116544.1         47069-47069         c
FEATURES             Location/Qualifiers
     source          1..1100
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q24"
     gene            1..1100
                     /gene="PLSCR5"
                     /note="phospholipid scramblase family member 5"
                     /db_xref="GeneID:389158"
                     /db_xref="HGNC:HGNC:19952"
     exon            1..147
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..950
                     /gene="PLSCR5"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="phospholipid scramblase family member 5 isoform
                     1"
                     /protein_id="NP_001078889.1"
                     /db_xref="CCDS:CCDS46931.1"
                     /db_xref="GeneID:389158"
                     /db_xref="HGNC:HGNC:19952"
                     /translation="MASKDAQNQRRGLPGFLPGAPDPDQSLPASSNPGNQAWQLSLPL
                     PSSFLPTVSLPPGLEYLSQLDLIIIHQQVELLGMILGTETSNKYEIKNSLGQRIYFAV
                     EESICFNRTFCSTLRSCTLRITDNSGREVITVNRPLRCNSCWCPCYLQELEIQAPPGT
                     IVGYVTQKWDPFLPKFTIQNANKEDILKIVGPCVTCGCFGDVDFEVKTINEKLTIGKI
                     SKYWSGFVNDVFTNADNFGIHVPADLDVTVKAAMIGACFLFDFMFFEHSLAGL"
     exon            148..323
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     exon            324..366
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     exon            367..587
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     exon            588..749
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     exon            750..911
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     exon            912..994
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1100
                     /gene="PLSCR5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1078..1083
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PLSCR5"
                     /note="hexamer: ATTAAA"
     polyA_site      1100
                     /gene="PLSCR5"
                     /note="major polyA site"
ORIGIN      
        1 atatgtaagc tgacaagagg cagacaaaca cgttctgaag ttttgtgcat gctgcgtttt
       61 ctctccttgc tgcaacaaga aaagcctttg ttttccaacc tggcaacctt tgaagaagtg
      121 actcagacat cttcatggcc tctaaagatg cccagaacca aagaagaggt ctgcctggtt
      181 ttcttcctgg agctccagac ccagaccaaa gccttcctgc ctcttccaat ccagggaacc
      241 aagcatggca gctgagtctc cctctgccaa gcagtttcct gccaacagtc agtctccctc
      301 ctggtctaga atatttaagc cagttagacc tgataattat acaccagcag gtggagctgc
      361 ttggaatgat acttggtact gagacctcca acaaatatga gattaaaaac agcttgggac
      421 aaagaattta ctttgcagtg gaggaaagca tctgcttcaa tcgtactttc tgttccactc
      481 tgcgatcttg caccctgagg atcacagata actcaggtcg agaggtcatt acagtgaaca
      541 ggcccttgag atgtaacagc tgctggtgcc cttgctacct acaagagtta gaaatccaag
      601 cccctcctgg tactatagtt ggttacgtta cgcagaagtg ggaccccttt ctgcctaaat
      661 tcacaatcca aaatgcaaac aaagaagata ttttgaaaat tgttggtcct tgtgtgacat
      721 gtggctgttt tggcgatgtg gattttgagg tgaaaaccat taatgaaaag cttacaattg
      781 ggaagatttc aaagtactgg tcaggatttg taaatgatgt cttcacaaat gctgacaatt
      841 tcggaattca tgttcctgca gatctagatg taacagtcaa agcagcaatg atcggtgcct
      901 gttttctctt tgattttatg ttctttgaac attcactggc tggattataa taaccaagat
      961 aatgaaaaca ataaaatatg cagaacatat ttcaaaatcc cttgggctct ggatttcatt
     1021 tctgaatggt ttgaatgttt gcttttttgt taaaaaaaaa tgttaattat tatatttatt
     1081 aaaacagttt aatgaggcaa
//
