LOCUS       XM_017006627            3872 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens plastin 1 (PLS1), transcript variant X3,
            mRNA.
ACCESSION   XM_017006627
VERSION     XM_017006627.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017006627.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..3872
                     /gene="PLS1"
                     /gene_synonym="DFNA76"
                     /note="plastin 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 22 ESTs, 361 long SRA
                     reads, 22 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 15 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:5357"
                     /db_xref="HGNC:HGNC:9090"
                     /db_xref="MIM:602734"
     CDS             326..2215
                     /gene="PLS1"
                     /gene_synonym="DFNA76"
                     /codon_start=1
                     /product="plastin-1 isoform X1"
                     /protein_id="XP_016862116.1"
                     /db_xref="GeneID:5357"
                     /db_xref="HGNC:HGNC:9090"
                     /db_xref="MIM:602734"
                     /translation="MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEAS
                     LPLPGYKVREIVEKILSVADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGI
                     TAIGGTSTISSEGTQHSYSEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLA
                     DGILLCKMINLSEPDTIDERAINKKKLTPFTISENLNLALNSASAIGCTVVNIGASDL
                     KEGKPHLVLGLLWQIIKVGLFADIEISRNEALIALLNEGEELEELMKLSPEELLLRWV
                     NYHLTNAGWHTISNFSQDIKDSRAYFHLLNQIAPKGGEDGPAIAIDLSGINETNDLKR
                     AGLMLQEADKLGCKQFVTPADVVSGNPKLNLAFVANLFNTYPCLHKPNNNDIDMNLLE
                     GESKEERTFRNWMNSLGVNPYINHLYSDLADALVIFQLYEMIRVPVNWSHVNKPPYPA
                     LGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLNEGNSTLTLALVWQLMRRYTLNVL
                     SDLGEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDKSISTSLPVLDLIDAIAPNAVR
                     QEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDLVEVKPKMVMTVFACLMGKG
                     LNRIK"
ORIGIN      
        1 agtggcgcga gcgcagcggc tacgcgggcg cggagaggta gccgcagagt ggacctgcag
       61 gtacttggat ctccagtggg agctgccctc tcgaaggcag gacagcggtg gcggcagcta
      121 agaaaactta ctaaccttgg ctctaccaac aaagaggcaa agatttttgt gccccttgga
      181 caagctgcag tgagggagca gtgcctgtgt cctcggaggc atggcaaatc cattagcgca
      241 tctatctgag tggagccgag ggcacagagt aggaggcggg ggaaccaaga tataaagacc
      301 tgaagatagt cttttctgtc caaagatgga aaacagtact actaccattt ctcgggagga
      361 gcttgaagaa ctacaagagg catttaataa aatagatatt gacaatagtg ggtatgtcag
      421 tgactatgaa cttcaagacc tgtttaagga agcaagcctt cctctgcctg gctacaaggt
      481 gcgcgagatt gtggagaaaa ttctatcagt tgctgacagc aacaaagatg gcaaaatcag
      541 ttttgaagag tttgtgtcac taatgcaaga attaaaaagc aaagatatca gcaaaacatt
      601 ccgaaaaata attaacaaga gggaagggat tactgctatt ggaggaactt caactatttc
      661 cagtgagggc acacagcatt cttattcaga ggaagaaaaa gtggcttttg ttaactggat
      721 aaacaaagcc ctggagaatg accctgactg taagcatctt atacccatga atcccaatga
      781 tgatagtctt ttcaagtcac ttgcagatgg catccttctt tgcaaaatga tcaacttatc
      841 tgaaccagat acaattgatg aaagagccat caataagaaa aagctcacgc cattcactat
      901 ttctgaaaat ttaaacctag ctctgaattc tgcctcagcc attggttgta cagtggtcaa
      961 cattggtgca tcagatctca aagaaggaaa acctcacttg gtcttgggac ttctctggca
     1021 gatcatcaaa gttggccttt ttgctgatat tgagatttcc aggaatgaag ctctgattgc
     1081 attgttaaat gaaggtgagg aactagagga gctgatgaag ctttctcccg aggaattact
     1141 gctgcgatgg gtgaactacc atctgaccaa tgcaggatgg cataccatca gcaacttcag
     1201 ccaagacatt aaggactcga gagcctattt tcatctgctt aatcagattg cccctaaagg
     1261 tggggaagat ggacctgcca ttgccattga cctttcagga attaatgaga caaatgacct
     1321 gaagcgtgct ggactcatgc ttcaagaagc agataaactg ggctgcaaac agtttgttac
     1381 tcctgcagat gtggtttcag gcaatcctaa acttaattta gcttttgtag ctaatttgtt
     1441 taacacatac ccgtgcctgc acaagccgaa taataatgac atcgatatga atttactgga
     1501 aggagagagc aaggaagaga gaacatttcg gaactggatg aattccttgg gagtcaaccc
     1561 atacattaat catttgtaca gtgaccttgc agatgcttta gtgatctttc agctctatga
     1621 gatgatccga gtgccagtca actggagcca tgtcaacaaa cctccttatc ctgcccttgg
     1681 agggaacatg aagaagattg aaaactgtaa ctatgcagtg gaacttggga agaacaaggc
     1741 caaattctcc ttggttggca ttgctgggca ggacctaaat gaagggaatt caacacttac
     1801 cctggcattg gtatggcagc tgatgagaag gtacacattg aatgtgttat cggatcttgg
     1861 agagggtgaa aaagtaaatg atgaaattat aattaaatgg gtcaatcaga ctcttaaaag
     1921 tgcaaacaaa aagacttcta tttccagctt caaggataaa tctataagca caagtttacc
     1981 tgtcctagat ttaatagatg ccattgcacc aaatgcagtt cgtcaagaaa tgatcaggag
     2041 agaaaactta tctgatgagg acaagctgaa caatgctaaa tacgccattt cagttgctcg
     2101 aaagatcggt gcccggatat atgcattacc tgatgacctc gtagaagtga aaccaaagat
     2161 ggttatgacg gtgtttgcat gcttaatggg aaaaggactg aacagaataa aataatcatt
     2221 tcatatgatt ttctgccaca ttaaacatat tgtatgcctc acagtttaca ggattctgaa
     2281 atgtagtggg tgtaaaacca gagattattt gtatgctcaa aatagttata tattcattaa
     2341 tgaattcaat atcctgttca tactagttag agctggtcag cctttttggg taacacagtt
     2401 aatttaccaa ctgatacaga taatagaata tattcataat caagctgata cttcatgatt
     2461 aaattatttt tgttgcttaa aagtcgtatt agacaagact aaatcattct tttttatggt
     2521 tcaaaaaaga tgaatacaaa cgtttttgca ggttctgctg tgaaatgtgg tttgattttt
     2581 ttggtgtgtt aattttgatc ataaatgcat tcatactcat aatccagttt aatcctttta
     2641 tttgcttcct ccaactattt aaagtggtcc aaaaacactt ttctgtaagt ttctatactg
     2701 tctaaaacct tatggtgacc agaattgttt attaatatca aactttttta tatatgagaa
     2761 ctaattcttg aataaacccc aaagttcact ctcttgttta agtagcagca gctttttact
     2821 taaaatttaa ttttaactac attgatactt tacacatcct agtttggtaa cacagcttta
     2881 actatgtcat gcaacatata tatgttggta ggatgttatt agagagatat gtgtgcatat
     2941 atattttttt gcacctgaat cacccagctt ttcataagtg gtatgtttaa ttggtcattc
     3001 agccaaccat cagtattttc cccccacaac atgtgtaaca cttttcagtc tgtggatatc
     3061 tgatacatta agatttcttt ttataagtat tcattttgaa tgtgcatata gttatttgac
     3121 cccttccaaa tacttgtagc caaacattgg ctagaacatc ccaagatatg ctgacactgt
     3181 cctgttagct tcatattata cttgctagtt taggtctcta tagaagccct atataattta
     3241 gaatatgccc actgaatatc tttaatagaa agtaacataa agctagtatt caatgtagag
     3301 tattttcata tgtttttcac agcccgttac aaattggcaa tgtttggtta atgtttgtat
     3361 tacttggaaa tcgctacagc ttggactatt tttttctaaa tttttagcat tagtccattt
     3421 ctgctgctaa caattgaatc cagaaatcta ctttctccat cttccactgt tagtgccagt
     3481 gagcaatact gttgtgcaac aaaaatgtca ctttatctca gtgtgaatga gtagtctaaa
     3541 ttccctttct accattgatt taaatatata tattggtaag agagactgcc catgtgttta
     3601 gaatagaatt ttttaaatga aatgatcaac aggtggaatt tgaaatatat tcttctacaa
     3661 aagagatttc tttccctttt atattttgat gattgttttc ttaagattaa gatatgttct
     3721 tgctctttta taagattatt taaattatgt ttccctctga ttttttttca ccattgtatt
     3781 tactaagtta ttggatttac atgaaatctg gcactttagg gtgttctttt tctcacagag
     3841 tatatttaat aaaaatgctg tgtatataga aa
//
