LOCUS       NM_001145024            1541 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens placenta expressed transcript 1 (PLET1), mRNA.
ACCESSION   NM_001145024 XM_001718626 XM_927535 XM_938130
VERSION     NM_001145024.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Depreter,M.G., Blair,N.F., Gaskell,T.L., Nowell,C.S., Davern,K.,
            Pagliocca,A., Stenhouse,F.H., Farley,A.M., Fraser,A., Vrana,J.,
            Robertson,K., Morahan,G., Tomlinson,S.R. and Blackburn,C.C.
  TITLE     Identification of Plet-1 as a specific marker of early thymic
            epithelial progenitor cells
  JOURNAL   Proc Natl Acad Sci U S A 105 (3), 961-966 (2008)
   PUBMED   18195351
  REMARK    GeneRIF: Plet-1 will thus provide an invaluable tool for genetic
            analysis of the lineage relationships and molecular mechanisms
            operating in the development, homeostasis, and injury in several
            organ/tissue systems
REFERENCE   2  (bases 1 to 1541)
  AUTHORS   Zhao,S.H., Simmons,D.G., Cross,J.C., Scheetz,T.E., Casavant,T.L.,
            Soares,M.B. and Tuggle,C.K.
  TITLE     PLET1 (C11orf34), a highly expressed and processed novel gene in
            pig and mouse placenta, is transcribed but poorly spliced in human
  JOURNAL   Genomics 84 (1), 114-125 (2004)
   PUBMED   15203209
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY364435.1, AY364431.1 and AP002884.5.
            
            On or before Feb 6, 2009 this sequence version replaced
            XM_938130.2, XM_927535.2, XM_001718626.1.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000338832.4/ ENSP00000341412.2
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-271               AY364435.1         2-272
            272-707             AY364431.1         1-436
            708-719             AP002884.5         103575-103586       c
            720-1541            AP002884.5         99380-100201        c
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q23.1"
     gene            1..1541
                     /gene="PLET1"
                     /gene_synonym="C11orf34"
                     /note="placenta expressed transcript 1"
                     /db_xref="GeneID:349633"
                     /db_xref="HGNC:HGNC:30053"
                     /db_xref="MIM:611904"
     exon            1..455
                     /gene="PLET1"
                     /gene_synonym="C11orf34"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..895
                     /gene="PLET1"
                     /gene_synonym="C11orf34"
                     /note="placenta-expressed transcript 1 protein"
                     /codon_start=1
                     /product="placenta-expressed transcript 1 protein
                     precursor"
                     /protein_id="NP_001138496.1"
                     /db_xref="CCDS:CCDS44732.1"
                     /db_xref="GeneID:349633"
                     /db_xref="HGNC:HGNC:30053"
                     /db_xref="MIM:611904"
                     /translation="MAVFHDMLLQPLGMFLCLSLQLSSATFIRYSSTCFTFDEYYTIT
                     LDIKASSHIYESNAVYSVFVPVNDSVYAVVMKTLDENSDSAGLWQRADKNCYSNSTYY
                     VKDQYMTVLEAQWQAPEPENITEVEIQAFTVQIRALPILSTLKLREKLSTLALAAKIP
                     QSSAFKPFFMITPKSIRLEGLANQVFSSPITEAIYILLAFLTSTLLF"
     exon            456..657
                     /gene="PLET1"
                     /gene_synonym="C11orf34"
                     /inference="alignment:Splign:2.1.0"
     exon            658..719
                     /gene="PLET1"
                     /gene_synonym="C11orf34"
                     /inference="alignment:Splign:2.1.0"
     exon            720..1541
                     /gene="PLET1"
                     /gene_synonym="C11orf34"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatgacaggc gtaaaagaaa accatattca ggacattccc tttcttgagc aaaactgcaa
       61 tttgcaaaat catcggtgac aggtaatggt gactggtgat tcattcctgg tgatgtcttg
      121 ggccaaattc cagaatccaa tgtatattca gaaggggcag ggagaagatc tgcatgtatg
      181 acttcaccca gaagccctgg catataaaca agaggtgagt tgtcagtttc acccaattcc
      241 aggcctagca ctttccaaac agactgagac catggcagtc ttccatgaca tgctgctgca
      301 gccactgggg atgtttctgt gcctcagtct gcagctttct tctgccacct ttataaggta
      361 cagtagcacc tgcttcacct ttgatgaata ctacaccata accctagaca tcaaggccag
      421 ttcacatatc tacgaaagca atgcagtcta ttctgtattt gttcccgtga atgacagcgt
      481 ctatgctgtg gtcatgaaaa ccttggacga gaacagtgac tcagcgggcc tctggcaaag
      541 agcggataaa aattgctaca gcaactccac gtattacgtg aaagatcaat acatgacggt
      601 cttagaggca cagtggcaag ctcctgaacc tgagaacata actgaagtgg agatacaagc
      661 tttcactgtc cagatcagag cgctgcctat actttctact ctgaagctaa gagaaaaact
      721 gtcaacctta gccttagctg ccaagattcc ccagagctca gccttcaagc ctttcttcat
      781 gattacaccc aagagtatca gactcgaagg cttggccaac caagtcttca gcagccccat
      841 cacagaggcc atttatatcc tgcttgcttt tctcaccagc acacttctct tctaaaggga
      901 agccagggaa acaattgttt ctgcctccac tgcatcctcc tacattcagt tccaagctag
      961 tgctgggaac cgaatgtgtg taaatgaagg ctttacattc tcaaatgtgc aactttgctg
     1021 ccacggcttc agaccaaaac aaagatctgg aggcactcat tggcaggctt gggtcacata
     1081 gatgttcatc tggatctttc aggacacata ttacactttt tgaaaatatt tagaactggc
     1141 cggaacttag tcacctaggt tctccctatt ggttgaacag gttggcagcc aattccacag
     1201 ccaatctcaa cttttgttca ctgccaaatg attcccctgc aacctctgag tttctgtggg
     1261 aagaatcctt ccttactttc aagatgatct cagatttcta accaaaccca ttcaggttac
     1321 aaggaacttc tgtgactcat gtgactcaag aaagaaagga gaaaggagaa atagctctga
     1381 ggctgctggc agcttcccat ttgtccacac cagtagattt tgaagggcaa gagaacagga
     1441 acgaaccatg tctgagaagc caatatagaa aaaaactatg ttataaaaac atttttgtca
     1501 caacaaataa attatacttt aaacaagaat aatgaatgtg t
//
