LOCUS       NM_001080475            9774 bp    mRNA    linear   PRI 27-JUL-2024
DEFINITION  Homo sapiens pleckstrin homology domain containing M3 (PLEKHM3),
            mRNA.
ACCESSION   NM_001080475 XM_371591
VERSION     NM_001080475.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9774)
  AUTHORS   Zhang,L., Zhou,Q., Qiu,Q., Hou,L., Wu,M., Li,J., Li,X., Lu,B.,
            Cheng,X., Liu,P., Lu,W. and Lu,Y.
  TITLE     CircPLEKHM3 acts as a tumor suppressor through regulation of the
            miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer
  JOURNAL   Mol Cancer 18 (1), 144 (2019)
   PUBMED   31623606
  REMARK    GeneRIF: CircPLEKHM3 is down-regulated in ovarian cancer. Patients
            with a lower circPLEKHM3 expression have a worse prognosis.
            CircPLEKHM3 was found to act as a tumor suppressor that inhibits
            cell proliferation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9774)
  AUTHORS   Virtanen,C., Paris,J. and Takahashi,M.
  TITLE     Identification and characterization of a novel gene, dapr, involved
            in skeletal muscle differentiation and protein kinase B signaling
  JOURNAL   J Biol Chem 284 (3), 1636-1643 (2009)
   PUBMED   19028694
  REMARK    GeneRIF: DAPR is a novel gene that binds to PKB/AKT and is a
            critical component for the differentiation of skeletal muscle
            myoblast cells into myotubes.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093698.5, AC083900.6 and AC096772.3.
            
            On Nov 23, 2018 this sequence version replaced NM_001080475.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.15055.1,
                                           SRR1803615.178961.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000427836.8/ ENSP00000417003.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               AC093698.5         17542-17680         c
            140-1067            AC083900.6         146344-147271       c
            1068-2003           AC083900.6         121965-122900       c
            2004-2149           AC083900.6         91681-91826         c
            2150-2343           AC083900.6         76240-76433         c
            2344-2407           AC083900.6         53828-53891         c
            2408-2565           AC083900.6         6419-6576           c
            2566-9774           AC096772.3         142336-149544       c
FEATURES             Location/Qualifiers
     source          1..9774
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q33.3"
     gene            1..9774
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /note="pleckstrin homology domain containing M3"
                     /db_xref="GeneID:389072"
                     /db_xref="HGNC:HGNC:34006"
                     /db_xref="MIM:619186"
     exon            1..139
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     exon            140..1067
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     CDS             458..2743
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /note="differentiation associated protein; PH
                     domain-containing family M member 3"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family M
                     member 3"
                     /protein_id="NP_001073944.1"
                     /db_xref="CCDS:CCDS42808.1"
                     /db_xref="GeneID:389072"
                     /db_xref="HGNC:HGNC:34006"
                     /db_xref="MIM:619186"
                     /translation="MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPE
                     LVGHEVLSNITDNGAMRNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTT
                     PDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWR
                     VVLKTTPLQQQQQQQPLLQGPHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYL
                     EIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMV
                     DTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYT
                     QNHSFQKKTSGLLPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAF
                     QPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEA
                     LKIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLT
                     AQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVS
                     KQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAE
                     DLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGF
                     ICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWQR
                     LNMDESLEEACTMFELSYQNT"
     exon            1068..2003
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2149
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     exon            2150..2343
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     exon            2344..2407
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2565
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..9774
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9755..9760
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /note="hexamer: AATAAA"
     polyA_site      9774
                     /gene="PLEKHM3"
                     /gene_synonym="DAPR; PLEKHM1L"
                     /note="major polyA site"
ORIGIN      
        1 gtaaacagag ccgggccggg atggtcagcg cccgggcggg ctgtcaccgt gaggcgggcg
       61 gcaggctgcg ggagtcaagc ccctccagga gcggactgaa ggccccgcag gtgaatggag
      121 agtagcagcc ggggcccagg aaatcaagga ttggcgtggc attgctttga caagtacttg
      181 ctgttgtctt cacagaggtc tcactgaaga ataatctcaa aggaacattt ggtctcccta
      241 tacatctgtt aatgcccatt agccactagc aaatgctttt aattaccagg aaaacatcaa
      301 ccactttggg tttggcctgc tccagggagc ccaatgaagg tttcttccag ttgtttccat
      361 agctctattg ctgaagcacc cctcttggtt gggtgaatgt tcatgaagcc atttctggaa
      421 ccagcttagg aggctaaggc ctcctggagc ctgtgacatg gaagctttgg aagtggatga
      481 tatcagccca gccttagaag ttacggagga attctttagt actttggata gtaatctaga
      541 aaaggctgtg cagcaggcag aggtttatgg gatccaggaa gtccctgaac tggtggggca
      601 tgaggtactc agtaacataa cagacaatgg tgctatgaga aatgtcacct ccctgggcaa
      661 ggggggcatg atttgggacc actgtaagag caggctctta gaaaccaaag ctcaaaatgt
      721 cttccctgcc aaagaacagt ttatggtcca gagagggaca accccagata atctttcctg
      781 gatggaacaa aaggaagcat caacctttaa tttcttcaat atctgtcagc gtcggaggga
      841 ccggcctcgt tctgtaaatg acttactgga tgagacctca actttcaagc cagggcatgc
      901 tcgatcacga tcagatatta cccaagtgga ctggagggta gtcctcaaaa ccacgccttt
      961 gcagcagcag caacagcagc agccattgct tcaaggcccg catgtcacca ggccatcttt
     1021 tctgttgccc tcaccaaata agatagaaga tgctcaagga aatactgaac acaagcagac
     1081 attcccaaac attctaaaga agggttacct ggagattaga aaggaccatg acagttactg
     1141 gcaaagctgt tatgcagaac tttcacctta caacttatac ttctacagcc tcgacagcag
     1201 tgggaatcaa aacctttatg ccacgtacca gctttcacac ttccagagca tatctgtttt
     1261 aggcaacctg gaggccagga tggtggatac tgttttgtat gacaacactc agctacagct
     1321 aaaggcagag tcaccatggg aggctttgga ctggggacag aagctttggg aagtagtgca
     1381 tgctgctgtg cccggttaca tggggcggca gaatgagctg acaatctcac cagggcttgg
     1441 ccatcatgat gactatacac agaatcatag tttccagaag aaaaccagtg ggctgctgcc
     1501 accgtcccct gtcctggaca gctccaaaca gtaccaaaac atcctcaaat cagggactct
     1561 ctacaggctg actgtccaaa acaactggaa ggcatttaca tttgtgctga gcagggctta
     1621 ccttatggct tttcagcctg gcaagctaga cgaggatcca ctgttgagct acaacgtgga
     1681 cgtgtgtctg gctgtccaga tggacaacct ggatggctgc gactcttgct ttcaagtcat
     1741 tttcccccag gatgtccttc gcctccgagc tgagacccga cagagggctc aggaatggat
     1801 ggaggctctg aagatagctg ccaatgtggc gaggagttca gagcaaaacc tgcaagtcac
     1861 actgaggaac aaacccaagg atcaaatggg tgggcatgaa ctcaggaaga acaaacgcca
     1921 atctgtgact accagcttcc tgagcatttt gacgactttg tctttggaac gaggactcac
     1981 tgctcagagt ttcaaatgtg caggctgcca gcgatccata ggtctttcca atgggaaagc
     2041 caaggtgtgc aactacagtg ggtggtatta ctgcagtagc tgccacgtgg atgacagctt
     2101 tctcattcca gcacgcatag tccacaactg ggatacttca aagtataagg tgtcgaagca
     2161 ggccaaggag tttctggagt acgtgtacga agagccgctc atcgacatcc agcaggagaa
     2221 cgccatgctg taccaccacg cagagccgct ggccgccgtg ctgcggctgc ggcagcggct
     2281 gaagtcgctc cgagcctatt tgttcagctg ccgggcagcg gtggcagagg atctccgccg
     2341 cagaattttc cccagagaat acctccttca acagatccac ctgtattcac ttgccgacct
     2401 gcagcaggta atagagggaa agctggctcc attcttgggc aaggtcatta aatttgccac
     2461 ctcacacgtg tacagctgca gtctttgtag ccagaagggg ttcatctgtg aaatctgtaa
     2521 caatggagag atcctctacc cttttgagga tatttcaaca agcaggtgtg aaagctgtgg
     2581 agccgttttc cattctgaat gcaaagaaaa gtctgtcccc tgcccgaggt gtgttcgccg
     2641 agagctgcag aagaagcaga agtctttctg gcagagactg aacatggacg agagtctaga
     2701 ggaggcttgc accatgttcg agctgtccta ccagaacacc tgactccagc cgacccgaag
     2761 gccagggatt caccaatcaa caatccatca gccccagagc ggcctcctaa ctagccagtt
     2821 agaccccttt ggaagaagag tatgtatcct cttcaactag atatagatat atatatttat
     2881 ttatatatac gcaaatacct atacgtcctg tacgtatgct ctgtgtacat cattgtccag
     2941 acgatccaca gaacctctgt ggctcgagaa actaccaata gctggattac acttagccaa
     3001 gaatttcagc tgcttgctcc cagacaaaac gtggtataca caatgcttta tagttcagac
     3061 tttttttttc tctctgtctc tcggtacatt ttattaccca agacacaaaa ggaagcattt
     3121 cctgcacaaa acagtgcttt aggttatttt tgtgttattt atttttagcc ttcacagagg
     3181 ctgaggtaac tgaggcaggc acccatcatc atctgtttca taagaaaacc ttcaaaacac
     3241 aagagactgc tgggtccttc caggacctgg tgtccgtggc gctcccgcct cagttcctcc
     3301 tgtggaggcg gggaatcacg taagcagagc cgatggctgg aaacaggagc caagccccct
     3361 ctgacagaaa gcatacaccc ctcatttatg aggagggctg gttctggttt tgaagttaat
     3421 ctcagaagtt tttttcctga gaagagaaga aacctctgcg accaataact gcgtgttgtc
     3481 ggtctgtttt tcggtactaa tcccatcacc cacctaatga tgtgacgctc caccgtgttt
     3541 tccaggctgt acacatggct ttcttaacag ttttcaacgg gtgcccatgg ttgatattta
     3601 tgattttttt catgatgctg gccggaggaa atgtcctggg gtggttgtta aagacatcgt
     3661 cgtgtagact ggtagataag gctatctagt aagtatattc ccaaagaggg tcgttttagt
     3721 ttcttttctc agaatcctgt ggaggcagtt cctacctatt cattttaagt gctttatttc
     3781 tcgttgttct tcctgcactt tcatttcgac ctttgtcaat gtgaccattc ttgctttctc
     3841 atttttttgt ttaaaaaatc agagtaatgt ggaacttcaa aataccaact ttggactatt
     3901 aagaaaatac aaacttacaa gtataattaa tgaattagat ctaatattat ttaaataaat
     3961 atatatatat acacacacat atataattgc caccttgaag taaaacaaag agtgctaaaa
     4021 taaataatag gagtaagaaa gagatctgct ttgctatttg gcaggtagtg ttctccagct
     4081 gcagtgccct tggaagagca cgtggcagtc actgtgacca aaacggcagg taggacagcc
     4141 ctgggaccct gacagctccc attccttccc cttaactctc cctagagcaa gaaaaatatg
     4201 tttataatgg aacagttctc agtagacttt atgagaagat tctgtagctt tcgcgctgag
     4261 cagatgcctt ctatgtcttc atggtttagt agttttgctg ctattaggat cagtggctca
     4321 caacatactt ggtacattca accccattgc tcctttcccc cacacgccgc ttccccaaga
     4381 ccccaactca tgatacttcc atccatctag agatgtgaca tttcagactg acttttgtgc
     4441 agttagatgt aagcatttta cctctcaacc cacaccagtt cctttggccc caggccacac
     4501 atttcacctt aatagctcaa caccatacat gcatttattt tctgactata cagtagccgc
     4561 aaccaaggct tgaaaacttg ttaaaaggcc agggccctat tcatgagacg cctgacggtg
     4621 ccttttaccc ttagaaaagc aggttgactt ttcccccact ctagttaaag agaatgttgc
     4681 acacaaaaga aaaagggtgg aaaatctcaa acacttggca acaggcaaac aaatttgatc
     4741 atctcctttc ctcctcctct tggtaaaata cagtatttat attttccagc ctcagagaag
     4801 atagcagaac atgatctttc acaagagaat tatagacctg cttattataa aacagatgtg
     4861 ctcccatggc aaagtgcctt ctccctccgc ccccagctcc ctgtcactgt agcttacttt
     4921 tgccttcgct gtaattaatg tatccgtgat tccaactgtc agcgaggcca ttcctagcac
     4981 actgcatttg gagacctgaa gtgcagtgcc atctcctccc cttgtaacat gtttgccctg
     5041 catacagaat ttcctctcct agctcacagg cacccagggt catacctgcc gagagtcaag
     5101 ggcgaaattc tggatccccg ttcaaaacat ctttgttttc accagtcccc atttagaggg
     5161 ccctgctaaa tacgagcagt ccctgtgaac tcctaaggag gactttccac ccacatcatt
     5221 ttctgcttat tttcaaaagg gaaacaaaaa atcgatgtgt tatcaccatc agctacccag
     5281 agctgggtcc atgtccagca ctcctgtttc ctctcctttt cgtaccaccc tgacagcttg
     5341 gtcggtgcca gccacaggcc tatgacattc tctgccacca ccaccaaaat ctgataggac
     5401 agagtggagc cagcttagga gttgggtctg ccatgaaaat tcaaaattgc tgttttcagc
     5461 ccagaatacc ttggcgcaca tgaacgccct tactgttttc aactttaaca aattacttgg
     5521 tgcactgtta ggtaattgtt ccactgctta gaaactgtcg aaacaaaagc aaatctgtgg
     5581 attaccacct ctttcagacc aaactaatac ctgcttttcc tcgtgttcca tttttcatcc
     5641 catattaaat atcttgcaca taaaacatat gaaaaaatgg ccaattaatc tcctggagct
     5701 ggcaactgac tccggggaac cgctttttgc tgaaaggctc attccctagt gtatcacttg
     5761 aggaaatccc tcctaaaagt gccagaaact catgtgtgag atcgtccaac cctggtgaaa
     5821 tgttggcatc taaccccgca gtaaagaagc cagttcctaa aatagacctc attttgcacc
     5881 gcggcaggaa ggccacaaag tacttaaaaa gccgtcaact ggaatggggg tagtgttctt
     5941 tccaggcccg ctttttccaa agttaaaagc ctctttatat gaaaaccatg taaactctca
     6001 gcagccccct ttgcttcact gccttttcta gggagtgcat tagagtcatt tttacgtctg
     6061 tagtgctaaa gggtcaccta gttaggagct ttaacatcgg attcgctgag agggtcatcg
     6121 gtttttgatt cttctagagt aggcctccac caagaaggga atacgtctaa tacttgggat
     6181 ctgtggtttg caacacaagt ggtatccctc agactcctga aaagggacta tgccgtgact
     6241 tccttccggc tgcagtgaga tccgaggtgt ttacaccacc ctagttgccg aatgcagcct
     6301 ttgctcagct agagtgtgtc ctctgacgga gcctggcctc tgtttttgtc tctgtgtgtt
     6361 gtgtgtacac actgaacgtg gacatcggat agttcttttc tgtgcctcct cagagaggct
     6421 tggcttccaa acctgggagt ttgttctcta cccattggct agaaaaggcc gtccataaat
     6481 tagtatatcc aggtgggact agcacgatgc cacgcacact gaacattttc tgcagagggg
     6541 cgttagcagt ggaagtagag acacattctg gtcctccttt agagtcaagc caatgctgtt
     6601 gctcgtgtat ttgtgcacaa ttattcatct ccgttgatct gacacactct cttgaaatca
     6661 ctagattatg aaacagatct tcacctcctg attccaatac tgcctggttt caacacaggg
     6721 gttgttttat ttttttactt ctcctagtaa atagagatgt gtataatttt tgcccatttt
     6781 atttcttgag ttgtctgcac cacttctttt cttactctga aataatgtga aaacgtgaag
     6841 ttggagcaag accttgaaag agcctccctc ctttgcgtga cctgaatcgg tagcggcact
     6901 ctctgtttcc cctgcctccg tgtcacttgt tagtgatggg cattaggagc ttcatatgtt
     6961 gcacaccttg tatcactctt ccgaccctga gtcaggtaga gctgtctgct cgaggtcgaa
     7021 tccagtgatg ggtgactaag ctctgctcgg ttaatgtaaa cagacaagtg ttgatttctg
     7081 tcatgtggaa cggtgtttcg acagttaagt ctagcaccca gtagtctcct tattggtaga
     7141 cgattctaat ttcattggat tcaaaaatct ctgactcaag ggtctttcct tagtgcgttt
     7201 taatgggtgc atggctgagg gaaaatccaa gtcattgtta aactctaggt aaaagacaag
     7261 agtatgggat accctcctaa ccataccggt agttgtcagt tttatttaaa gtgggttcca
     7321 cttggccagg attggtggct cacgcctgta atcccagccc tttgggaggc caaggcaggc
     7381 agatcacttg aggtcaggag tttgagacca gccgggccaa aaatggtgaa atcaggtcta
     7441 tactaaaaat aaaaaaatta ggctgaacgt agtggctcat gcctgtaatc ccaacacttt
     7501 gaaggccgag gtgggtgaat cacttgaggt caggagtttg aggccagcct ggccaacatg
     7561 gtgaaacccc cctctttact aaaaatacaa aaattagctg agtgttttgg tggatgccta
     7621 taatcccagc tacttgggag actgaggcag gagaattgct tgaacctggg aggcagaggt
     7681 tgcagtgagc cgagattgcg ccactgcact ccagcctggg cgacagagca agactccgtc
     7741 tcaaaaaaaa aaaaaaaagt aagttccaaa tgatcatgtt ttgtggcact gtcttcgtaa
     7801 agtggccgct ggtgtgatgg aaagcattgc taaactcaag tgagacaact gctgttttgc
     7861 tttggatttt ccctgtgaaa agagaagcca ctgcctgttc gtcttgttag aaagacaaga
     7921 ctttgaatga agttccagac tttgaatgaa gttccagact ttgaatgaag ctggttgttg
     7981 cccagagtag aagattcagg cacctacagc aactcacagc aactcctaac tcttaggagg
     8041 gctccctcct attggccgtg aagctgcaaa ccagcctctc tcttttccct ggatcttcct
     8101 tgcccctagt tctgagcccc agcccagagg caggcctcat ggctaataaa ccagctagag
     8161 gacagctggg gcctgtggct ccttctccat gttggccttc ccttgtgtct cttgtccctg
     8221 taggagtgcc ttatagtact gtctcgtgct tctagtctag tctgaaccac ttgaagcctg
     8281 caggaccctt caactaaatc tggatccctt tgcttcttcc ctgctggcta ctcttcatat
     8341 agatgctctt ggagcctgtg cattccatga tgcatgtcag aactctcacc ttgttcagcc
     8401 tggtgtgcct taacctcagg agtaaaggga atcatgtcgg aaacacgtcg ttaaagtaga
     8461 atggtacaaa cattggcttc ttagtgccat tagcactttt accaggaaat gcaaaagatg
     8521 caaccacata atgttttcac tttgttttat gctgttcttc aatcgctctt tttgtttatt
     8581 tgtttgtttg ctttcattaa ccaaactcag gggaatgtca tgatgtcacc aaggccaatg
     8641 ggtagagaaa taaaaaccag ccatccataa ttgaatctgt aaagtcagtg aacttagcct
     8701 tttcaggttc aaaattacac aaacacaagg attttcttat ctttcacctt tcaaaggttt
     8761 tctttttatt ttgccacctg ttttccaaat aagaagtggg aagcctctta gataaattgt
     8821 gataaaaatg tctctttgtt tggcgtgagc tatcaaatta gctttgtgtg tccactgagc
     8881 catcaaatta ggctttggct gctggaggcc taggttctag ctttggtcac ctatcagaat
     8941 cttactgtta cgctgggcat ggtggcatgt gcctacagtc ccagctattt gggaggctga
     9001 agtgggtaga ttgcttgagc ccaggagcct gtgcaatatg gtgagaccca tctcaaaaaa
     9061 caaacaaaaa aagaagtaga atcttactgt gaatagctac tagcctaccc tagaagatat
     9121 atattttaaa tctgtttctt aggaatagta gctaaaagaa ggaatggcca aaggagggaa
     9181 agtggttggc cgcagcggct cacacctgta atcccagctc tttgggaggc tggggtggga
     9241 ggatcactgg agcccaggag ttcaagacaa gtctgggcaa gatagcgaga ccctcatctc
     9301 tttgaaaaat atatatatat actttttttt ttaaaggaga gaaaatgctt aggttgcaaa
     9361 tggagagtat tgaacgtggt gatgtaaaaa acttctgcaa aacttgttct gtagctcctg
     9421 ggtcaggtct atgccatttt ttcttatatc tgctcacaca gtacagaaat gactaaaatt
     9481 ttgggtctgg gctgttatat cactttgtgt taagttattt gtagtagcta atgtgctaac
     9541 ttatatatgt gttctttctg ttttttggat tttacctttt gttttggcat aacttatcta
     9601 tatttttgtt tacattattt taaaaatatc agtaactgta ataatataaa attgaagttg
     9661 tattgttgac aatacctcta gtttttaagg tcatctgtca cataatttaa gtgcaccagt
     9721 tcctaatgta taaagttctc tctctctctc tctcaataaa caatgcagaa aata
//
