LOCUS       NM_001329630            5530 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens pleckstrin homology domain containing A7 (PLEKHA7),
            transcript variant 1, mRNA.
ACCESSION   NM_001329630
VERSION     NM_001329630.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5530)
  AUTHORS   Segal,D., Maier,S., Mastromarco,G.J., Qian,W.W., Nabeel-Shah,S.,
            Lee,H., Moore,G., Lacoste,J., Larsen,B., Lin,Z.Y.,
            Selvabaskaran,A., Liu,K., Smibert,C., Zhang,Z., Greenblatt,J.,
            Peng,J., Lee,H.O., Gingras,A.C. and Taipale,M.
  TITLE     A central chaperone-like role for 14-3-3 proteins in human cells
  JOURNAL   Mol Cell 83 (6), 974-993 (2023)
   PUBMED   36931259
REFERENCE   2  (bases 1 to 5530)
  AUTHORS   Wu,Y.Y., Xiao,Y.F., Tian,L.X., He,B., Liu,J., Li,Z.B., Yang,H.,
            Chen,Y., Luo,Q., Li,B.S. and Yang,S.M.
  TITLE     The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote
            gastric cancer invasion and metastasis
  JOURNAL   Oncogene 42 (14), 1144-1156 (2023)
   PUBMED   36823376
  REMARK    GeneRIF: The hTERT-p50 homodimer inhibits PLEKHA7 expression to
            promote gastric cancer invasion and metastasis.
REFERENCE   3  (bases 1 to 5530)
  AUTHORS   Sluysmans,S., Salmaso,A., Rouaud,F., Mean,I., Brini,M. and Citi,S.
  TITLE     The PLEKHA7-PDZD11 complex regulates the localization of the
            calcium pump PMCA and calcium handling in cultured cells
  JOURNAL   J Biol Chem 298 (8), 102138 (2022)
   PUBMED   35714771
  REMARK    GeneRIF: The PLEKHA7-PDZD11 complex regulates the localization of
            the calcium pump PMCA and calcium handling in cultured cells.
REFERENCE   4  (bases 1 to 5530)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   5  (bases 1 to 5530)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   6  (bases 1 to 5530)
  AUTHORS   Takeuchi,F., Isono,M., Katsuya,T., Yamamoto,K., Yokota,M.,
            Sugiyama,T., Nabika,T., Fujioka,A., Ohnaka,K., Asano,H., Yamori,Y.,
            Yamaguchi,S., Kobayashi,S., Takayanagi,R., Ogihara,T. and Kato,N.
  TITLE     Blood pressure and hypertension are associated with 7 loci in the
            Japanese population
  JOURNAL   Circulation 121 (21), 2302-2309 (2010)
   PUBMED   20479155
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 5530)
  AUTHORS   Hong,K.W., Jin,H.S., Lim,J.E., Kim,S., Go,M.J. and Oh,B.
  TITLE     Recapitulation of two genomewide association studies on blood
            pressure and essential hypertension in the Korean population
  JOURNAL   J Hum Genet 55 (6), 336-341 (2010)
   PUBMED   20414254
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 5530)
  AUTHORS   Fei,Y., Cheng,Z.J., Liu,X.S., Wang,F., Zong,G.Q., Wang,W., Ge,Z.
            and Liu,S.L.
  TITLE     [The expression of P120 catenin in pancreatic carcinoma and the
            relationship between the T755G polymorphism of P120 catenin gene
            and pancreatic carcinoma]
  JOURNAL   Zhonghua Wai Ke Za Zhi 47 (23), 1809-1812 (2009)
   PUBMED   20193553
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   9  (bases 1 to 5530)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   10 (bases 1 to 5530)
  AUTHORS   Meng,W., Mushika,Y., Ichii,T. and Takeichi,M.
  TITLE     Anchorage of microtubule minus ends to adherens junctions regulates
            epithelial cell-cell contacts
  JOURNAL   Cell 135 (5), 948-959 (2008)
   PUBMED   19041755
  REMARK    GeneRIF: PLEKHA7 binds with p120catenin and non-centrosomal minus
            end protein Nezha and plays a linker role between adherens junction
            and non-centrosomal microtubules.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN293588.1, BC071599.1, AC127033.11, DR731351.1, BE873160.1,
            AC026639.6 and BC032761.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001329630.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074967.964797.1,
                                           SRR14038197.2172504.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000531066.6/ ENSP00000435389.1
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 CN293588.1         3-4
            3-1902              BC071599.1         1-1900
            1903-1903           AC127033.11        116270-116270
            1904-2948           BC071599.1         1902-2946
            2949-3586           DR731351.1         1-638
            3587-3859           BE873160.1         40-312
            3860-5330           AC026639.6         128704-130174       c
            5331-5530           BC032761.1         895-1094
FEATURES             Location/Qualifiers
     source          1..5530
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.2-p15.1"
     gene            1..5530
                     /gene="PLEKHA7"
                     /note="pleckstrin homology domain containing A7"
                     /db_xref="GeneID:144100"
                     /db_xref="HGNC:HGNC:27049"
                     /db_xref="MIM:612686"
     exon            1..99
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..3829
                     /gene="PLEKHA7"
                     /note="isoform 1 is encoded by transcript variant 1;
                     pleckstrin homology domain containing, family A member 2;
                     PH domain-containing family A member 7; pleckstrin
                     homology domain containing, family A member 7; pleckstrin
                     homology domain-containing family A member 6"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family A
                     member 7 isoform 1"
                     /protein_id="NP_001316559.1"
                     /db_xref="CCDS:CCDS86182.1"
                     /db_xref="GeneID:144100"
                     /db_xref="HGNC:HGNC:27049"
                     /db_xref="MIM:612686"
                     /translation="MAAATVGRDTLPEHWSYGVCRDGRVFFINDQLRCTTWLHPRTGE
                     PVNSGHMIRSDLPRGWEEGFTEEGASYFIDHNQQTTAFRHPVTGQFSPENSEFILQEE
                     PNPHMSKQDRNQRPSSMVSETSTAGTASTLEAKPGPKIIKSSSKVHSFGKRDQAIRRN
                     PNVPVVVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISP
                     VAPEDRISRKYSFKAVHTGMRALIYNSSTAGSQAEQSGMRTYYFSADTQEDMNAWVRA
                     MNQAAQVLSRSSLKRDMEKVERQAVPQANHTESCHECGRVGPGHTRDCPHRGHDDIVN
                     FERQEQEGEQYRSQRDPLEGKRDRSKARSPYSPAEEDALFMDLPTGPRGQQAQPQRAE
                     KNGMLPASYGPGEQNGTGGYQRAFPPRTNPEKHSQRKSNLAQVEHWARAQKGDSRSLP
                     LDQTLPRQGPGQSLSFPENYQTLPKSTRHPSGGSSPPPRNLPSDYKYAQDRASHLKMS
                     SEERRAHRDGTVWQLYEWQQRQQFRHGSPTAPICLGSPEFTDQGRSRSMLEVPRSISV
                     PPSPSDIPPPGPPRVFPPRRPHTPAERVTVKPPDQRRSVDISLGDSPRRARGHAVKNS
                     SHVDRRSMPSMGYMTHTVSAPSLHGKSADDTYLQLKKDLEYLDLKMTGRDLLKDRSLK
                     PVKIAESDTDVKLSIFCEQDRVLQDLEDKIRALKENKDQLESVLEVLHRQMEQYRDQP
                     QHLEKIAYQQKLLQEDLVHIRAELSRESTEMENAWNEYLKLENDVEQLKQTLQEQHRR
                     AFFFQEKSQIQKDLWRIEDVTAGLSANKENFRILVESVKNPERKTVPLFPHPPVPSLS
                     TSESKPPPQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVTSPLQSPTKAKPK
                     VEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQC
                     VNGDSRVELRSYVSEPELATLSGDMAQPSLGLVGPESRYQTLPGRGLSGSTSRLQQSS
                     TIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALV
                     RERKRTLGQGERTGLPSSRYLSRPLPGDLGSWKREQDFDLQLLERVVQGEKKDKEENG
                     WLKVQAMPVTELDLEPQDYDLDISRELSKPEKVSIPERYVELDPEEPPSLEELQARYR
                     KAEKIRNILARSSMCNLQPTSGQDQNSVADLDLQLQEQERIINISYALASEASQRSKQ
                     VAAQAVTDP"
     exon            100..176
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            177..234
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            235..318
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            319..430
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            431..535
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            536..608
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            609..709
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            710..885
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1356
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1879
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            1880..1966
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            1967..2020
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2021..2089
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2170
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2320
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2321..2422
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2531
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2532..2758
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2759..2947
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            2948..3065
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            3066..3169
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            3170..3370
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            3371..3529
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            3530..3663
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            3664..3806
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     exon            3807..5530
                     /gene="PLEKHA7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5513..5518
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PLEKHA7"
                     /note="hexamer: ATTAAA"
     polyA_site      5530
                     /gene="PLEKHA7"
                     /note="major polyA site"
ORIGIN      
        1 gcgctcggcg aacatggcgg cggcgacggt cgggcgggac actttacctg agcattggtc
       61 ctacggggtg tgccgggatg gccgcgtctt cttcatcaat gaccagctcc gctgcacgac
      121 ctggctgcat ccgcgcaccg gggagcccgt caactcgggc cacatgatcc gctcagacct
      181 gccccgcggc tgggaggagg gcttcacgga ggagggcgcc agctacttca tcgaccataa
      241 ccagcagacc acagcattca ggcatcctgt gacgggacag ttttctccag aaaatagtga
      301 attcattctt caagaagagc cgaatccaca tatgtcgaag caagacagaa accaaagacc
      361 gtccagcatg gtcagtgaaa catccacggc tgggaccgcc tccaccctgg aggccaagcc
      421 tggacccaag atcataaagt ccagcagtaa agtccacagc tttgggaaga gagaccaggc
      481 cattcggagg aaccccaatg ttcccgtggt ggtgaggggc tggctgcaca agcaggacag
      541 ttctgggatg aggctgtgga aaaggaggtg gtttgtgctt gctgattact gcttatttta
      601 ctataaagac agccgagaag aagcggtcct cgggagcatc cccttgccca gctacgtgat
      661 ctctcctgtg gcccctgagg atcgcataag ccgcaaatat tcctttaagg ctgtgcacac
      721 ggggatgcga gcgctcatct ataacagctc cacagcgggc tctcaggccg agcagtcagg
      781 catgaggacc tactacttca gtgccgacac ccaggaggac atgaacgctt gggtcagggc
      841 catgaaccag gctgcacagg tgctgtctcg atcgtcactg aagagggata tggagaaggt
      901 ggagcggcag gctgtccccc aggccaacca cacagagtcc tgtcacgaat gtggccgggt
      961 gggacccgga catacgagag attgtcctca tcgtggccat gatgacattg tcaacttcga
     1021 gaggcaggag caggagggag agcagtaccg ttcccagagg gacccactgg agggcaagcg
     1081 ggaccggagc aaggccaggt ctccgtactc gccagccgag gaggatgcct tgtttatgga
     1141 tttacccact ggcccaagag gccagcaggc acagccccaa cgggcagaga agaatggaat
     1201 gctgcctgcc tcatatggcc caggagaaca gaatgggact ggtgggtacc agcgggcctt
     1261 tcctcccagg accaaccctg aaaaacacag ccaaaggaag agcaatctgg cccaggtgga
     1321 gcactgggca agggcccaga aaggggatag caggagtctt cccttggacc agacgcttcc
     1381 tcgccagggt cctggccaat ccctgtcctt cccagaaaac taccagactc ttcccaagag
     1441 cacccgacac ccctcggggg gctcctcgcc acctccccga aacctgccaa gtgactacaa
     1501 gtatgcgcag gaccgagcca gccacctgaa gatgtcgagt gaagagcgcc gggcgcaccg
     1561 ggatggcacc gtgtggcagc tctacgagtg gcagcagcgc cagcagttcc ggcacggcag
     1621 ccccacagcg cccatctgcc ttggctcccc agagttcacc gaccagggcc ggagcaggag
     1681 catgctagag gtgccccgct ccatctctgt gcctccatct ccctcggaca tccctccccc
     1741 aggaccccca agggtcttcc caccccggcg gccacacaca ccagcagagc gagtcacagt
     1801 gaagccaccg gaccagagga ggagtgtgga catctcgctg ggggattctc caaggagggc
     1861 acggggccac gctgtcaaga actcatctca tgtggaccga cgctccatgc cctccatggg
     1921 ttacatgacc cacaccgtca gcgctcccag tttacatgga aaatcggctg atgataccta
     1981 cctccagctg aagaaagacc tggagtacct ggatctaaag atgacaggcc gggaccttct
     2041 caaggatcga agtctgaagc ctgtgaagat cgctgagagc gacactgacg tcaaactgag
     2101 catcttctgt gaacaagaca gggtcctcca ggacttggaa gacaagatac gagcccttaa
     2161 agagaacaaa gaccagctag aatctgtgct ggaggtgttg cacagacaga tggagcagta
     2221 ccgagaccag ccccagcact tggagaagat tgcctaccag cagaagttgc tgcaggagga
     2281 ccttgtccat atccgagctg agctctccag agagtccact gagatggaaa atgcttggaa
     2341 cgaatacctg aagttggaga atgatgtgga acagctgaag cagaccctgc aggagcaaca
     2401 cagaagagcc ttttttttcc aggagaaatc gcagatacag aaagatctat ggagaattga
     2461 agatgtcact gcaggcctga gtgcaaataa agagaacttc agaattctag tggagtcagt
     2521 aaaaaatccg gagagaaaaa cggtgccttt gtttcctcac ccgcctgtgc cttcactctc
     2581 aacttctgag agcaagccgc ccccacagcc cagtcctccc accagccctg tgcggacccc
     2641 tctggaggtt cgactcttcc cccagctgca aacctacgtg ccgtaccgac ctcacccacc
     2701 ccagctgagg aaagtgacat ccccccttca gtcaccaact aaggcgaagc ccaaagttga
     2761 agatgaagca cctcccaggc ccccactccc cgaactctac agcccagagg accagccccc
     2821 ggctgtgccg cctctgccaa gagaggccac catcatccgg cacacatctg tgcggggcct
     2881 caagcggcag tcagacgaga ggaagcgaga ccgggagctg gggcagtgtg tgaatgggga
     2941 ttccagggtg gagctgcggt cgtatgtcag tgagcctgag ctggcgaccc tcagcgggga
     3001 catggcccag ccctccctag gacttgtggg ccctgagagc aggtaccaga cgctgccagg
     3061 cagagggctc tcagggtcca cgtcaaggct ccagcagtcg tccaccattg ctccctacgt
     3121 cacactccgg aggggtctca atgccgaaag cagcaaggcg accttcccta gacctaagag
     3181 tgccttggag cgcctgtact caggggatca ccagcgaggc aagatgagtg cagaggagca
     3241 gctggagcgc atgaagcgac accagaaggc cctggtccga gagcgcaaga ggacactggg
     3301 ccaaggggag aggacgggcc tgccctcatc tcgctacctc agccggccgc tccctggaga
     3361 tcttggctca tggaagcgtg agcaggactt tgacctgcag ttgctggaac gggtcgtgca
     3421 aggggaaaaa aaggacaagg aggagaatgg ctggttgaaa gtgcaggcca tgcctgtcac
     3481 tgagttggac ctggagcctc aagactatga cttggacatc agcagagagc tgtccaaacc
     3541 agagaaggtg tcaatccctg agcgctacgt ggagctagat cccgaagagc cacccagcct
     3601 tgaggagctg caggcgcggt accgcaaagc cgagaagatc cgcaacatcc tcgcccggtc
     3661 aagcatgtgc aacctacagc cgacctcagg ccaggaccag aacagtgtgg ctgacctgga
     3721 cttgcagctg caggagcagg agcgcatcat caacatctcc tacgccctgg cctccgaggc
     3781 ctcccagcgt agcaagcagg tggcagccca ggcagtgact gacccgtgac ccagcatgca
     3841 aagaagcctg gagccagggg cccagtggaa ccagcttcct ccaaggagat gacctttctg
     3901 cccccaagga aaccccttcc agctgagcag ggaatccggc cggaggaagg agcagcttac
     3961 cgactgcggg tgttcaccac aggccaggcc ctaatatgca cccactagtt tagctcagac
     4021 tcctctctac atatgaatgg caaaggcact tttgatatac actgtaaaat acactgtatt
     4081 ttagaatcgg aatctatttt ctaatgttcc cctcaagggc tgagtggcag gaaggttgag
     4141 gatgcaggac tttgcagctg cacgtacaga ttcaggtact tctgggtgac aggtgttgtg
     4201 ggggcaggaa gggcggggca agccgaggct agtccaactt ccaatgacct caggagaaag
     4261 tgagatttaa agaggtgttc ccagtagact ccagcaagag gctggttggc gtgctgtctg
     4321 ggagaagagg ggcccttggc tgcagagatc agctgtccct gacctgatga ccagctctgt
     4381 gtgaaactcc acgaggatca cacgtggagc ccaagtctgt gccttgcccc ttgggtttgg
     4441 cttaggggca acagtgtgtt caagaggact ggggcccaca acctgccccc aggcttcctc
     4501 cagcaaaagg ctcttgtcag aaagaaaaaa gcagtttgct atcttttttt ttttttgaga
     4561 tggagtttca ctcttgttgc ccaggctgga gtgcaatggc acgatctcgg ttcactgcaa
     4621 cctctgcctc ctgggttcaa gtgattctcc tgcctcagcc tcccaagtag ctaggattac
     4681 aggcatgtgc caccacgccc ggctaatttt gtatttttag tagagacggg ggtttcttca
     4741 tgttggtgag gttggtctcg aactcctgac ctcaggtgat tcatccgctt cagcatccca
     4801 aagtgttggg attacagccg tgagccacca cgcccagcct gctttcattt ttaacagtac
     4861 acattgaaat acagaaaagg tgagaggaag caactttcat tgtatcgtag caataaactc
     4921 cacactgggt gacatctacc tagaaatccc ttccctctaa ccaggccatg atgggaacct
     4981 ttgctgcctg cccttggaga accccggatt ggcttccctg ggactcaggt ctggtggcag
     5041 gagggcagca gtgtgccccc accatccctc atggcctgcc gccagcaggg ccataatggc
     5101 aggactttga tttgacttcc agccccacat gaggaggggg gctaccaagc caggtgcagt
     5161 gtttgtggcc ctttatttaa gttgttttct tatattattc tgcatataaa caatgacgtt
     5221 taaatggaaa aaacaacaac aacgaaaacc tccattgggt ggagccacac tttaaatgaa
     5281 aatttctctt tgactatgct cagaaaaaaa aatagaattt tgaatatatc tagcagttgt
     5341 tgtctatttt taactaactc catatgctgc cagtatcgac ttcatgacat ttgccaaaat
     5401 aaaattttat ttttgccttt ataagatttt cttggaaaaa atgaaatgaa tattttgcaa
     5461 gaaaaagtta atttaaaaat gtaatggttt gcaaaaaaaa tgtgatgtac agattaaaat
     5521 attaacctga
//
