LOCUS       XM_047421875           14671 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens plectin (PLEC), transcript variant X14,
            mRNA.
ACCESSION   XM_047421875
VERSION     XM_047421875.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14671
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..14671
                     /gene="PLEC"
                     /gene_synonym="EBS1; EBS5A; EBS5B; EBS5C; EBS5D; EBSMD;
                     EBSND; EBSO; EBSOG; EBSPA; HD1; LGMD2Q; LGMDR17; PCN;
                     PLEC1; PLEC1b; PLTN"
                     /note="plectin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 mRNAs, 62 ESTs, 4021
                     long SRA reads, 5 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     83 samples with support for all annotated introns"
                     /db_xref="GeneID:5339"
                     /db_xref="HGNC:HGNC:9069"
                     /db_xref="MIM:601282"
     CDS             58..13647
                     /gene="PLEC"
                     /gene_synonym="EBS1; EBS5A; EBS5B; EBS5C; EBS5D; EBSMD;
                     EBSND; EBSO; EBSOG; EBSPA; HD1; LGMD2Q; LGMDR17; PCN;
                     PLEC1; PLEC1b; PLTN"
                     /codon_start=1
                     /product="plectin isoform X14"
                     /protein_id="XP_047277831.1"
                     /db_xref="GeneID:5339"
                     /db_xref="HGNC:HGNC:9069"
                     /db_xref="MIM:601282"
                     /translation="MAGPLPDEQDFIQAYEEVREKYKDERDRVQKKTFTKWVNKHLIK
                     AQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVK
                     LVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQRMVEG
                     YQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGV
                     TRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPDVQDGELQLRWQEYRELVLLLLQW
                     MRHHTAAFEERRFPSSFEEIEILWSQFLKFKEMELPAKEADKNRSKGIYQSLEGAVQA
                     GQLKVPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVTKLQMEAGLCEE
                     QLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLKDGRHPQGE
                     QMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQVAQVTLQSVQRRPELEDSTLRYLQ
                     DLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIERARSDEGQLSP
                     ATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLNEKEEEEVGF
                     DWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPARPTVESFQAAL
                     QTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVT
                     RLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLKPRHPAHPMRGRLPLLAVCDYK
                     QVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVTRLEA
                     QHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELH
                     YQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELK
                     DIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAE
                     KVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLR
                     AHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQ
                     QRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAW
                     LQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIK
                     DYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS
                     ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR
                     MQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI
                     RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ
                     AEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETA
                     QRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAE
                     RELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ
                     RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA
                     AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEE
                     AARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKE
                     AENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLR
                     QRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA
                     AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESAR
                     QLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEE
                     AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA
                     QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE
                     LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFL
                     QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR
                     LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA
                     ERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ
                     SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE
                     KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR
                     RRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE
                     VTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRL
                     AQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILL
                     EAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISL
                     FQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADP
                     SDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEARDV
                     FEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITV
                     VEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRAL
                     RGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTV
                     DEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDA
                     QLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGE
                     LQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVT
                     VWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRA
                     PVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEK
                     VSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQL
                     LSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVP
                     VDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLP
                     LKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQ
                     RAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARII
                     SLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLS
                     AEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDP
                     YTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKD
                     THDQLSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLTFRGLRK
                     QITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLS
                     VYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLS
                     AERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVE
                     VAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLK
                     EKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEE
                     ITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQYRAGTLSITEFADMLSG
                     NAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITE
                     AMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQK
                     AFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEAL
                     QRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQS
                     TKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYG
                     RRYASGSSASLGGPESAVA"
ORIGIN      
        1 agagtggccg ccgggtgctg gaggctccgc tgcaccccgc gccccgcgcc cgccggcatg
       61 gccggcccgc tgcccgacga gcaggacttc atccaggcct acgaggaggt gcgcgagaag
      121 tacaaagatg agcgggatcg tgtgcagaag aaaaccttca ccaagtgggt caacaagcac
      181 ctcatcaagg cccagaggca catcagtgac ctgtatgaag acctccgcga tggccacaac
      241 ctcatctccc tgctggaggt cctctcgggg gacagcctgc cccgggagaa ggggaggatg
      301 cgtttccaca agctgcagaa tgtccagatt gccctggact acctccggca ccgccaggtg
      361 aagctggtga acatcaggaa tgatgacatc gctgacggca accccaagct gacccttggc
      421 ctcatctgga caatcattct gcacttccag atctcagata tccaggtgag tgggcagtcg
      481 gaggacatga cggccaagga gaagctgctg ctgtggtcgc agcgaatggt ggaggggtac
      541 cagggcctgc gatgcgacaa cttcacctcc agctggagag acggccgcct cttcaatgcc
      601 atcatccacc ggcacaagcc cctgctcatc gacatgaaca aggtgtaccg gcagaccaac
      661 ctggagaacc tggaccaggc cttctctgtg gcggagcggg acctgggagt gacgcggctc
      721 ctggaccctg aggacgtgga tgtccctcag cccgacgaga agtccatcat cacctacgtc
      781 tcgtcgctgt atgacgccat gccccgcgtg ccggacgtgc aggatgggga gctgcagctg
      841 cgctggcagg agtaccggga gctggtgctg ctgctgcttc agtggatgcg acaccacacg
      901 gccgcctttg aggaacgcag gttcccctcc agcttcgagg agattgagat cctgtggtct
      961 cagttcctga agtttaagga gatggagcta ccagccaagg aggccgacaa gaacaggtcc
     1021 aagggcatct accaatccct ggagggagcg gtgcaagcag gccagctcaa ggtgccccct
     1081 ggctaccacc cgctggatgt ggagaaggag tggggcaagc tgcacgtggc catcctggag
     1141 cgggagaagc agctccgcag cgagtttgag aggctggagt gtcttcagcg catcgtgacc
     1201 aagctgcaga tggaggcggg gctgtgtgag gagcagctga accaggccga cgccctgctg
     1261 cagtcggatg tccggctgct ggctgcaggc aaagtgccac agcgggcggg ggaggtggaa
     1321 cgggacttgg acaaggcgga tagcatgatc cggctgctct tcaacgacgt gcagaccctc
     1381 aaggatggac ggcacccgca gggcgagcag atgtaccgca gggtgtaccg tctgcacgag
     1441 cgcctggtag ccatccgcac cgagtacaac ctacggctga aggcaggcgt ggcggcccct
     1501 gcaacccagg tggcccaggt gactctgcag agtgtgcaga ggcgccccga gctggaggac
     1561 tccactctgc gctacctgca ggacctgctg gcctgggtgg aggagaacca gcaccgtgtg
     1621 gatggcgctg agtggggtgt ggacctgccc agcgtggagg cgcagctggg cagccaccga
     1681 ggcctgcacc agtccatcga agaattccgg gccaagatcg agcgggcacg gagtgacgag
     1741 ggccagctct cccccgccac ccggggtgcc taccgtgact gcctgggtcg gctggacctg
     1801 cagtacgcca agctgctgaa ctcctccaag gcccgcctca ggtccctgga gagcttgcac
     1861 agctttgtgg cagccgccac taaggagcta atgtggctga atgagaagga ggaggaggag
     1921 gtgggcttcg actggagcga ccgcaacacc aacatgaccg ccaagaagga gagctactcg
     1981 gcgctgatgc gggagctgga gctgaaggag aagaagatca aggagctcca aaatgctggg
     2041 gaccggctgc tgcgggagga ccacccggcc cggcccacgg tggagtcctt ccaggcggcc
     2101 ctgcagacgc agtggagctg gatgctacag ctgtgctgct gtatcgaggc acacctgaag
     2161 gagaacgctg cctactttca gttcttctca gatgtgcggg aggccgaggg gcagttgcag
     2221 aagctgcagg aggcactgcg taggaaatac agttgtgatc gctccgccac cgtcacccgg
     2281 ctggaggacc tgctgcagga tgcccaggac gagaaggaac agctgaacga gtacaagggc
     2341 cacctctcag gcctggccaa gcgggccaag gccgtcgtgc agctgaagcc ccgccaccca
     2401 gcccacccca tgcggggccg cctgcccctg ctggccgtgt gcgactataa gcaggtggag
     2461 gtgactgtgc acaagggtga cgagtgccag ctggtgggcc ctgcacagcc gtcccactgg
     2521 aaggtgctca gcagctccgg cagcgaggcc gccgtgccct ccgtgtgctt cctggtgccc
     2581 ccgcccaacc aggaggccca ggaggccgtc accaggctgg aggcccagca ccaggccctg
     2641 gtcacgctgt ggcaccagtt gcacgtggac atgaagagcc ttctggcctg gcagagcctt
     2701 cgccgcgacg tgcagctcat ccgctcctgg tccctggcca cgttccgcac cctgaagcca
     2761 gaggagcagc gccaagccct gcacagcctg gagctgcact accaggcctt cctgcgggac
     2821 agccaggacg cgggcggctt cggacccgag gaccggctga tggctgagcg cgagtacggc
     2881 tcctgcagcc accactacca gcagctgctg cagagcctgg aacagggtgc acaggaagag
     2941 tctcgctgcc agcgctgcat ctccgagctc aaagacatcc ggctgcagct ggaggcctgt
     3001 gagacgcgca ccgtgcaccg cctgcggctg ccgctggaca aagagccggc acgggagtgt
     3061 gcccagcgca tcgccgagca gcagaaggca caggcagagg tggaggggct gggcaagggg
     3121 gtcgcccggc tctctgccga ggccgagaag gtcttggccc taccagagcc atcgcctgcg
     3181 gcccccacgc tgcgctcgga gctggagctg acgctgggca agctggagca ggtccgcagc
     3241 ctgtctgcca tctacctgga gaagctcaag accatcagcc tggtgatccg cggcacgcag
     3301 ggggccgagg aggtgctcag ggcccacgag gagcagctca aggaggccca ggccgtgccg
     3361 gccaccctcc cggagctcga ggccaccaag gcctctctga agaagctgcg ggcccaggcc
     3421 gaggcacagc agcccacgtt cgacgccctg cgggatgagc tgcggggggc acaggaggtg
     3481 ggggagcgac tgcagcagcg gcacggggag cgggacgtgg aggtggagcg ctggcgggag
     3541 cgggtcgccc agttgcttga gcgctggcag gctgtgctgg cccagaccga cgtgcggcag
     3601 cgcgagctcg agcaactggg ccgccagctg cgttactacc gcgagagtgc agaccccttg
     3661 ggcgcctggc tgcaggacgc caggcggcgg caggagcaga tccaggccat gccgctggcc
     3721 gacagccagg ctgtgcggga gcagctgcgg caggagcagg ccctgctgga ggagatcgag
     3781 cgccacggcg agaaggtcga ggagtgccag aggtttgcga aacagtacat caacgccatc
     3841 aaggactatg aactccagct ggtgacgtac aaggcgcagc ttgagccggt ggcctccccg
     3901 gccaagaagc ccaaggtcca gtcgggatca gagagtgtca tccaggagta cgtggacctg
     3961 cgtacgcact acagcgagct gaccacactg acgagccagt acatcaagtt catcagcgag
     4021 actctgcggc gcatggagga ggaggagagg ctggctgagc agcagcgggc agaggagcgc
     4081 gagcggctgg ccgaggtgga ggccgcgctg gagaagcagc ggcagctggc cgaggcgcac
     4141 gcccaggcaa aggcacaggc ggagcgggag gcgaaggagc tgcagcagcg catgcaggag
     4201 gaggtggtgc ggcgggagga ggcggcggtg gacgcgcagc agcagaagcg cagcattcag
     4261 gaggagctgc agcagctgcg gcagagctcg gaggcggaga tccaggccaa ggcccggcag
     4321 gcagaggcgg ctgagcgcag ccggctgcgc atcgaggagg agatccgcgt ggtgcgcctg
     4381 cagttggagg ccaccgagcg ccagcgtggc ggggctgagg gggagctgca ggcactgcgt
     4441 gcacgggcgg aggaggctga ggcacaaaag cgacaggcgc aggaggaggc cgagcgcttg
     4501 cggaggcagg tgcaggacga gagccagcgt aagcggcagg cggaggtgga gctggcctcg
     4561 cgcgtgaagg ccgaggccga ggcggcgcgc gagaagcagc gggccctgca ggccctggag
     4621 gagctgcggc tgcaggcgga ggaggcggag cggcgcctgc ggcaggccga ggtggagcga
     4681 gcgcggcagg tacaggtggc cctggagacg gcgcagcgca gtgcagaggc ggagctgcag
     4741 agcaaacgcg cctccttcgc cgagaagacg gcacagctgg agcgctccct gcaggaggaa
     4801 cacgtggctg tggcacagct gcgggaggag gctgagcggc gggcacagca gcaggccgag
     4861 gccgagcggg cgcgcgagga ggcagagcgg gagctggagc gctggcagct caaggccaac
     4921 gaggcgctac ggctgcggct gcaggcggag gaggtggcgc agcagaagag cctggcgcag
     4981 gccgaggctg agaagcagaa ggaggaggcg gagcgcgagg cgcggcggcg cggcaaggcg
     5041 gaggagcagg ccgtccggca gcgggagctg gctgaacaag agctggagaa gcagcggcag
     5101 ctggcggaag gcaccgcgca gcagcgcctg gccgcggagc aggagttgat ccggctgcgg
     5161 gccgagacgg agcaggggga gcagcagcgg cagctgctgg aggaggagct ggcccggctg
     5221 cagcgtgagg cggctgcagc cacgcagaaa cggcaggagc tggaagccga gctggccaag
     5281 gtgcgggccg agatggaggt gctgctggcc agcaaggcga gggctgagga ggagtcgcgc
     5341 tccaccagcg agaagtccaa gcagaggctg gaggccgagg ccggccggtt ccgcgagctg
     5401 gccgaggagg ccgcccgcct gcgtgccctg gcggaagagg ccaagcggca gcggcagctg
     5461 gccgaggaag acgcggcgcg gcagcgggcc gaggcggagc gggtgcttgc ggagaagctg
     5521 gccgccatcg gcgaggccac gcggctcaag acggaggcgg agatcgcgct caaggagaag
     5581 gaggcggaga acgagcgcct gcggcggctg gcggaggacg aggccttcca gcggcggcgg
     5641 ctggaggagc aggccgcgca acacaaggct gacatcgagg agcgcctggc ccagctgcgc
     5701 aaggcatcgg acagcgagct ggagcggcag aaggggctgg tggaggacac gctgaggcag
     5761 cggcggcagg tggaggagga gatcctggcg ctgaaggcga gcttcgagaa ggcggccgct
     5821 ggcaaggcgg agctggagct ggagctggga cgcatccgca gcaacgcgga ggacacgctg
     5881 cgcagcaagg agcaggccga gctggaggct gcgaggcagc ggcagctggc ggcggaggag
     5941 gagcggcggc gccgtgaggc tgaggagcgc gtgcagaaga gcctggcggc cgaggaggag
     6001 gccgcacggc agcggaaggc ggcgctggag gaagtcgagc ggctgaaagc caaggtggag
     6061 gaggcgcggc gcctgcggga gcgagcggag caggagtcgg cgcggcagct gcagctggcc
     6121 caggaggccg cccagaagcg gctgcaggcg gaagagaagg cacacgcctt cgcggtgcag
     6181 cagaaggagc aggagctaca gcagacgctg cagcaggagc agagcgtgct ggaccagctg
     6241 cgcggcgagg cggaggcggc ccggcgggcg gctgaggagg cggaggaggc ccgggtgcag
     6301 gcggagcgtg aggcggcgca gtcccggcgg caggtggaag aggccgagcg gctgaagcag
     6361 tcggcagagg agcaggcaca ggcccgggct caggcacagg cggctgcaga gaagctgcgc
     6421 aaggaggccg agcaagaggc ggcgcggcgg gcacaggcgg agcaggcggc cctgcggcag
     6481 aagcaggcag ctgacgcgga gatggagaag cataagaaat tcgccgagca gacgctgcgg
     6541 cagaaggcgc aggtggagca ggagctgaca acactgcggc tgcagctgga ggagaccgac
     6601 caccagaaga acctgctgga cgaggagctg cagcggctga aggcggaggc cacggaggcc
     6661 gcacgccagc gcagccaggt ggaggaggag ctcttctcgg tgcgcgtgca gatggaggag
     6721 ctgagcaagc tcaaggcacg catcgaggct gagaaccgcg cactcatctt gcgtgacaag
     6781 gacaatacgc agcgcttcct gcaggaggag gctgagaaga tgaagcaggt ggcggaggag
     6841 gccgcgcggc tgagtgtggc ggcccaagag gctgcgcgac tgcggcagct ggcagaggag
     6901 gacctggcac agcagcgggc cttggcagag aagatgctca aggagaagat gcaggcggtg
     6961 caggaggcca cgcgactcaa ggctgaggcg gaactgctgc agcagcagaa ggagcttgcg
     7021 caggagcagg cgcggcggct gcaggaggac aaggagcaga tggcgcagca gctggcggag
     7081 gagacgcagg gcttccagcg gacgctggag gccgagcggc agcggcagct ggagatgagc
     7141 gctgaggctg agcgcctcaa gctgcgtgtg gccgagatga gccgagccca ggcccgcgct
     7201 gaggaggacg cccagcgctt ccggaagcag gcggaggaga tcggtgagaa gctgcaccgc
     7261 acggagctcg ccacccagga gaaggtgacc ctggtgcaga cactggagat ccagcgacag
     7321 cagagtgacc atgatgccga gcgcctgcgg gaggccatcg ctgagctgga gcgtgagaag
     7381 gagaagctcc aacaggaggc caaactgctg cagctcaagt ctgaggagat gcagacggtg
     7441 cagcaggagc agctgctgca ggagacgcag gccctgcagc aaagcttcct ctctgaaaag
     7501 gacagcctgc tacagcggga gcgcttcatc gagcaggaga aggccaagct ggagcagctc
     7561 ttccaggacg aggtggccaa ggcacagcag ctgcgtgagg agcagcagcg gcagcagcag
     7621 cagatggagc aggaacggca gcggctggtg gccagcatgg aggaggcgcg gcggcggcag
     7681 catgaggccg aggagggcgt gcggcgcaag caggaggagc tgcagcagct ggagcagcag
     7741 cggcggcagc aggaggagct gctggctgag gagaaccaga ggctgcgtga gcagctgcag
     7801 ctcctggagg agcagcaccg ggccgcgctg gcgcactcag aggaggtcac tgcctcgcag
     7861 gtggctgcca caaagaccct gcccaatggc cgggatgcac ttgatggccc cgcggcagag
     7921 gcagagccgg agcacagctt cgatggcctg cggcggaagg tgtcagctca gaggctgcag
     7981 gaggccggca tcctgagtgc ggaggagctg cagcggttgg cgcagggcca caccacggtg
     8041 gacgagctcg cacggcggga agacgtgcgc cactacctgc agggccgcag cagtatcgca
     8101 gggctgttgc tgaaggccac caatgagaag ctgagtgttt acgccgccct gcagaggcag
     8161 ctgctgagtc ccggcacggc cctcatcctg ctggaggcgc aggcggcctc aggcttcctg
     8221 ctggaccctg tgcggaaccg gcggctgacc gtcaacgagg ctgtgaagga gggtgtggtg
     8281 ggccccgagc tgcaccacaa gctgctgtcg gccgagcgcg ccgtcactgg ctacaaggac
     8341 ccctacactg gccagcagat ctctctcttc caagccatgc agaagggcct catcgtccgg
     8401 gagcacggca tccgcctgct ggaggcccag atcgccacgg gcggcgttat cgaccccgtg
     8461 cacagccacc gcgtgcccgt ggacgtggcc taccggcgcg gctacttcga cgaggagatg
     8521 aaccgcgtcc tggcggaccc cagcgacgac accaagggct tctttgaccc caacacgcac
     8581 gagaacctca cgtacctgca gctactggag cgctgcgtgg aggaccccga gacgggcctg
     8641 tgccttctgc cactcacgga taaggctgcc aagggcgggg agctggtcta cactgactcc
     8701 gaggcccggg acgtctttga gaaggccacc gtgtctgcgc cgttcggcaa gttccagggc
     8761 aagacggtga ccatttggga gatcatcaac tcggaatact tcacggcaga gcagcggcgg
     8821 gacctgctgc ggcagttccg cacgggccgg atcacagtgg agaagatcat caagatcatc
     8881 atcacggtgg tggaggagca ggagcagaag ggccggcttt gctttgaggg cctgcgcagc
     8941 ctggtgccag ccgccgagct gctggagagc agggtcatcg accgcgagct ctaccagcag
     9001 ctgcagcgag gtgagcgctc tgtgcgagac gtagccgagg tggacactgt gcggcgggct
     9061 ctccggggtg ccaacgtcat cgcgggtgta tggctggagg aggcggggca gaagctgagt
     9121 atctacaatg ccctgaagaa agacctgctg ccatccgaca tggccgtggc cctgttggaa
     9181 gcccaggccg gcaccgggca catcatcgac cccgccacca gcgcccggct gaccgtggac
     9241 gaggcagtgc gtgctggcct ggtgggcccc gagtttcatg agaagctgct atcagccgag
     9301 aaggctgtga cagggtacag ggacccctac acagggcaga gcgtctccct gttccaggcc
     9361 ctgaagaagg gcctcattcc ccgggagcag ggcctgcgcc tgttggacgc ccagctgtcc
     9421 acgggcggca tcgtggaccc cagcaagagc caccgcgtgc ccctggatgt cgcctgcgcc
     9481 cgaggctgcc tggatgagga gaccagcagg gccctgtcgg caccaagggc cgacgccaag
     9541 gcctacagtg accccagcac aggggagccg gccacctacg gcgagctcca gcagcggtgc
     9601 cggcccgacc agctgaccgg gctgagcctg ctgccgctct cagaaaaggc tgctcgggcc
     9661 cggcaggagg agctctactc agagctgcag gcccgtgaga cctttgaaaa gaccccggtt
     9721 gaggtccccg tgggtggctt caagggcagg acggtgacgg tgtgggagct catcagctct
     9781 gagtacttca ctgcggagca gcggcaggag ctgttgcgtc agttccgcac gggcaaggtc
     9841 accgtggaga aggtcatcaa gattctcatt accatcgtgg aggaggtgga gaccctgcgg
     9901 caggagaggc tgtccttcag cggcctccgt gcccctgtgc cagccagcga gctcctggct
     9961 tccggggtcc tcagcagagc ccagtttgag cagctcaagg acggcaagac gacggtcaag
    10021 gacctttcgg agctgggctc cgtgcggacg ctgctgcagg gcagtggctg cctcgccggc
    10081 atctacctgg aggacaccaa ggagaaggtg tccatctacg aggccatgcg ccggggcctg
    10141 ctgagagcca caacggctgc gctcctgctg gaggcgcagg cggccactgg cttcctggtg
    10201 gaccccgtgc ggaaccagcg cctgtatgtc cacgaggccg tgaaggcggg cgtggtgggc
    10261 cccgagcttc acgagcagct gctgtctgcc gagaaggccg tcaccggcta cagagacccc
    10321 tactcgggca gcaccatctc cctcttccag gccatgcaga agggcctggt tctccggcag
    10381 cacggcatcc gcctgctgga ggcccagatc gccacgggcg gcatcatcga ccccgtgcac
    10441 agccaccgcg tgcctgtgga cgtggcctac cagcgcggct acttcagtga ggagatgaac
    10501 cgcgtcctgg cggaccccag cgacgacacc aagggcttct ttgaccccaa cacgcatgag
    10561 aacctcacgt acaggcagct gctggagcgg tgcgtggagg accccgagac gggcttgcgc
    10621 cttctgccac tgaaaggggc ggagaaggct gaggtggtgg agaccacgca ggtgtacact
    10681 gaggaggaga caagaagggc atttgaagag acacagatcg acattcccgg cggcggcagc
    10741 cacggcggct ccaccatgtc cctgtgggag gtgatgcagt cggacctgat ccccgaggag
    10801 cagcgggccc agctgatggc tgacttccag gccggccggg tgaccaagga acgcatgatc
    10861 atcatcatca tcgagatcat tgagaagaca gagatcatcc gccagcaggg tctggcctcc
    10921 tacgactacg tgcgccgccg cctcacggct gaggacctgt tcgaggctcg gatcatctct
    10981 ctcgagacct acaacctgct ccgggagggc accaggagcc tccgtgaggc tctcgaggcg
    11041 gagtccgcct ggtgctacct ctatggcacg ggctccgtgg ctggtgtcta cctgcccggt
    11101 tccaggcaga cactgagcat ctaccaggct ctcaagaaag ggctgctgag tgccgaggtg
    11161 gcccgcctgc tgctggaggc acaggcagcc acaggcttcc tgctggaccc ggtgaagggg
    11221 gagcggctga ctgtggatga ggctgtgcgg aagggcctcg tggggcccga gctgcacgac
    11281 cgcctgctct cggctgagcg ggcggtcacc ggctaccgtg acccctacac cgagcagacc
    11341 atctcgctct tccaggccat gaagaaggag ctgatcccta ctgaggaggc cctgcggctg
    11401 ctggatgccc agctggccac cggcggcatc gtggaccccc gcctgggctt ccaccttccc
    11461 ctggaggtgg cttaccagcg tggctacctc aacaaggaca cgcacgacca gctgtcagag
    11521 cccagcgagg tgcgcagcta cgtggacccg tccaccgacg agcgcctcag ctacacgcag
    11581 ctgctcaggc ggtgccgtcg tgacgacggc accggccagc tgctcctgcc actgtcggac
    11641 gcccgcaagc tgaccttccg tggcctgcgg aagcagatca ccatggagga gctggtgcgc
    11701 tcgcaggtca tggacgaggc cacggcgctg cagctgcggg agggcctgac ctccatcgag
    11761 gaggtcacca agaacttgca gaagttcctg gaaggcacca gctgcatcgc tggtgtcttc
    11821 gtggacgcca ccaaggaacg gctctcggtg taccaggcca tgaagaaggg catcatccgc
    11881 cccggcacag cctttgagct cctggaggcg caggcggcca ccggttacgt catcgacccc
    11941 atcaagggac tgaagctgac ggtggaggag gctgtgcgta tgggcattgt gggccccgag
    12001 ttcaaggaca agctgctgtc ggccgagcgc gccgtcactg ggtacaagga cccctactct
    12061 gggaagctca tctccctctt ccaggccatg aagaagggcc tgatcctgaa ggaccatggc
    12121 atccgcctgc tggaggccca gatcgccacg ggcggcatca tcgaccctga ggagagccac
    12181 cggctgcccg tggaggtggc ctacaagcgc ggcctcttcg atgaggagat gaacgagatc
    12241 ctgaccgacc cctcggacga caccaagggc ttctttgacc ctaacacgga ggagaacctc
    12301 acctacctgc agctgatgga gcgttgtatc actgaccccc agacgggcct gtgtctcttg
    12361 ccgctgaagg agaagaagcg ggagcggaag acgtcctcca agtcctccgt gcgcaagcgc
    12421 cgagtggtca tcgtggaccc cgagacgggc aaggagatgt cagtgtacga ggcctaccgc
    12481 aagggcctga ttgaccacca gacgtacctg gagctgtccg agcaggagtg cgagtgggag
    12541 gagatcacca tctcctcctc ggacggcgtg gtcaagtcca tgatcatcga ccgccgctcc
    12601 gggcgccagt acgacatcga tgatgccatc gccaagaacc tcatcgaccg ctcggcactg
    12661 gaccagtacc gcgccggcac gctctccatc accgagttcg ccgacatgct ctcgggcaac
    12721 gccggtggtt tccgctcccg ttcctcctcg gtgggatcct cctcctccta ccccatcagc
    12781 cccgccgtct ccaggaccca gctggcctcc tggtcagacc ccactgagga gacgggcccc
    12841 gtggctggca tcctggacac ggagacgctg gagaaggtgt ccatcaccga ggccatgcac
    12901 cggaacctgg tggataacat cacggggcag cggctgctgg aggcgcaggc ctgcaccggg
    12961 ggcatcatcg accccagcac cggtgagcgc ttccctgtca ccgacgccgt caacaagggc
    13021 ctggtggaca agatcatggt ggaccgcatc aacctggccc agaaggcctt ctgcggcttc
    13081 gaggacccac gcaccaagac caagatgtcg gccgcccagg ccctgaagaa gggctggctc
    13141 tactacgagg ccggccagcg cttcctggag gtgcagtacc tgaccggcgg cttgatcgag
    13201 cccgacacgc cgggccgcgt gcccctggac gaggccctgc agcgcggcac ggtggacgcc
    13261 cgcaccgcac agaagctgcg tgacgtgggc gcctactcca agtacctcac ctgccctaag
    13321 accaagctca agatctccta taaggacgcg ctggaccgca gcatggtgga ggagggcacg
    13381 gggctgcggc tgctggaggc tgccgcgcag tccaccaagg gctactacag cccctacagc
    13441 gtcagcggct ccggctctac cgctggctcc cgcaccggct cgcgcaccgg ctcccgggcc
    13501 ggctcccgcc gcggcagctt tgacgccacc ggctccggct tctccatgac cttctcttca
    13561 tcctcctact cctcctcggg ctacggccgc cgctacgcct cggggtcctc ggcctccctg
    13621 gggggccctg agtctgccgt ggcctgaggc tgcctgcgcc caccccgctc tgcatgcggc
    13681 ccagcccggc tcccaccgag gcgcgggggc cgttttcaac gcttaaaggt gtcttcctcc
    13741 caagtggtgc ctaaagttta accaaaaaga ccagactaat atattaatat atatctgctg
    13801 tccagacagc ctgtatcttg ggggacaggg ctggcccagc cctgctggcc gcctcacccc
    13861 ctcgggtctc ctcactccct tctacctgcc actcacacag ccaggtgcct tggagggtcc
    13921 caagctgggc cccagcccac cctcctgtct tcccagggta gcccgcctgc cagtcctagc
    13981 tgcacagggc agctgggccc aaccctgtct gtagagggcc ctggtgtttc tagcactggc
    14041 ctgcacggtg ggccttgctg gggacggggg gccccagtca gcctctctcc cagtctaccc
    14101 agagaagccc cttccccatg ggaagacgag gccctcgggc ccagccccca cagtgctgtc
    14161 tgatctgtgc tttccagctc accccccaca ctcactcctg agacccctgg cctccggcgt
    14221 cagcctccag cctctgttcc cctagtaagt gccttccatg tcggcctcta accccaggcc
    14281 ccgaggaccc agacccagtg gggaggcgga cgttccagcc ggcatggctg ggaactgcag
    14341 acctgtcctc ctggtgggtc caggggcccc tccagcttgt ggagccccac actggggtgc
    14401 cgcctgcccg tctctctccc atggagcccc agcccccttt gggcccaggg acaccagcca
    14461 ggctctgtgc tgaccctcct gttgcaccca gccctggtct cagcagcgac cacccctgcc
    14521 tccaccctct gagctttgca tgttccacta accccgggcg ggtggcaggt ggaggtgtca
    14581 ggctgctggc gcctctgcaa gggcagaaca ctaacctgac cgtgggcggg gccttgcggt
    14641 atccgccccc aataaaagca attccaacct t
//
