LOCUS       XM_047421872           14786 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens plectin (PLEC), transcript variant X7,
            mRNA.
ACCESSION   XM_047421872
VERSION     XM_047421872.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14786
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..14786
                     /gene="PLEC"
                     /gene_synonym="EBS1; EBS5A; EBS5B; EBS5C; EBS5D; EBSMD;
                     EBSND; EBSO; EBSOG; EBSPA; HD1; LGMD2Q; LGMDR17; PCN;
                     PLEC1; PLEC1b; PLTN"
                     /note="plectin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 mRNAs, 66 ESTs, 4035
                     long SRA reads, 4 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     88 samples with support for all annotated introns"
                     /db_xref="GeneID:5339"
                     /db_xref="HGNC:HGNC:9069"
                     /db_xref="MIM:601282"
     CDS             50..13762
                     /gene="PLEC"
                     /gene_synonym="EBS1; EBS5A; EBS5B; EBS5C; EBS5D; EBSMD;
                     EBSND; EBSO; EBSOG; EBSPA; HD1; LGMD2Q; LGMDR17; PCN;
                     PLEC1; PLEC1b; PLTN"
                     /codon_start=1
                     /product="plectin isoform X7"
                     /protein_id="XP_047277828.1"
                     /db_xref="GeneID:5339"
                     /db_xref="HGNC:HGNC:9069"
                     /db_xref="MIM:601282"
                     /translation="MSGEDAEVRAVSEDVSNGSSGSPSPGDTLPWNLGKTQRSRRSGG
                     GAGSNGSVLDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHN
                     LISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLT
                     LGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGR
                     LFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEK
                     SIITYVSSLYDAMPRVPDVQDGELQLRWQEYRELVLLLLQWMRHHTAAFEERRFPSSF
                     EEIEILWSQFLKFKEMELPAKEADKNRSKGIYQSLEGAVQAGQLKVPPGYHPLDVEKE
                     WGKLHVAILEREKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLA
                     AGKVPQRAGEVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIR
                     TEYNLRLKAGVAAPATQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAE
                     WGVDLPSVEAQLGSHRGLHQSIEEFRAKIERARSDEGQLSPATRGAYRDCLGRLDLQY
                     AKLLNSSKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYS
                     ALMRELELKEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAH
                     LKENAAYFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQLN
                     EYKGHLSGLAKRAKAVVQLKPRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGP
                     AQPSHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMK
                     SLLAWQSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPE
                     DRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRL
                     RLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRS
                     ELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLP
                     ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERV
                     AQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLA
                     DSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA
                     SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQR
                     AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQ
                     QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA
                     EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAR
                     EKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE
                     KTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR
                     LQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG
                     TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR
                     AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQL
                     AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQR
                     RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFE
                     KAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKS
                     LAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE
                     KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRR
                     QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM
                     EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ
                     VEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARL
                     SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE
                     QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA
                     EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELER
                     EKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK
                     LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL
                     QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRD
                     ALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVR
                     HYLQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRR
                     LTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRL
                     LEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLT
                     YLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKT
                     VTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRS
                     LVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQK
                     LSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKL
                     LSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVP
                     LDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLP
                     LSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQE
                     LLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQ
                     FEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTA
                     ALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGS
                     TISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRV
                     LADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYT
                     EEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKER
                     MIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLRE
                     ALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFL
                     LDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELI
                     PTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDP
                     STDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEAT
                     ALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFE
                     LLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLI
                     SLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILT
                     DPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKR
                     RVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDR
                     RSGRQYDIDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSS
                     YPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLE
                     AQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAA
                     QALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVG
                     AYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYSVSGSGSTA
                     GSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGSSASLGGPESA
                     VA"
ORIGIN      
        1 agtctggctg cggcggcaga gctgaagtga gcggagccac caggaggcca tgtcgggtga
       61 ggacgctgag gtccgggcag tctctgaaga tgtctccaat ggaagcagtg gctcgcccag
      121 ccctggggac acactgccct ggaaccttgg gaaaacgcag cggagccggc gcagcggggg
      181 tggcgctggg agcaacggga gtgtcctgga cccagctgag cgggcggtca ttcgcatcgc
      241 agatgagcgg gatcgtgtgc agaagaaaac cttcaccaag tgggtcaaca agcacctcat
      301 caaggcccag aggcacatca gtgacctgta tgaagacctc cgcgatggcc acaacctcat
      361 ctccctgctg gaggtcctct cgggggacag cctgccccgg gagaagggga ggatgcgttt
      421 ccacaagctg cagaatgtcc agattgccct ggactacctc cggcaccgcc aggtgaagct
      481 ggtgaacatc aggaatgatg acatcgctga cggcaacccc aagctgaccc ttggcctcat
      541 ctggacaatc attctgcact tccagatctc agatatccag gtgagtgggc agtcggagga
      601 catgacggcc aaggagaagc tgctgctgtg gtcgcagcga atggtggagg ggtaccaggg
      661 cctgcgatgc gacaacttca cctccagctg gagagacggc cgcctcttca atgccatcat
      721 ccaccggcac aagcccctgc tcatcgacat gaacaaggtg taccggcaga ccaacctgga
      781 gaacctggac caggccttct ctgtggcgga gcgggacctg ggagtgacgc ggctcctgga
      841 ccctgaggac gtggatgtcc ctcagcccga cgagaagtcc atcatcacct acgtctcgtc
      901 gctgtatgac gccatgcccc gcgtgccgga cgtgcaggat ggggagctgc agctgcgctg
      961 gcaggagtac cgggagctgg tgctgctgct gcttcagtgg atgcgacacc acacggccgc
     1021 ctttgaggaa cgcaggttcc cctccagctt cgaggagatt gagatcctgt ggtctcagtt
     1081 cctgaagttt aaggagatgg agctaccagc caaggaggcc gacaagaaca ggtccaaggg
     1141 catctaccaa tccctggagg gagcggtgca agcaggccag ctcaaggtgc cccctggcta
     1201 ccacccgctg gatgtggaga aggagtgggg caagctgcac gtggccatcc tggagcggga
     1261 gaagcagctc cgcagcgagt ttgagaggct ggagtgtctt cagcgcatcg tgaccaagct
     1321 gcagatggag gcggggctgt gtgaggagca gctgaaccag gccgacgccc tgctgcagtc
     1381 ggatgtccgg ctgctggctg caggcaaagt gccacagcgg gcgggggagg tggaacggga
     1441 cttggacaag gcggatagca tgatccggct gctcttcaac gacgtgcaga ccctcaagga
     1501 tggacggcac ccgcagggcg agcagatgta ccgcagggtg taccgtctgc acgagcgcct
     1561 ggtagccatc cgcaccgagt acaacctacg gctgaaggca ggcgtggcgg cccctgcaac
     1621 ccaggtggcc caggtgactc tgcagagtgt gcagaggcgc cccgagctgg aggactccac
     1681 tctgcgctac ctgcaggacc tgctggcctg ggtggaggag aaccagcacc gtgtggatgg
     1741 cgctgagtgg ggtgtggacc tgcccagcgt ggaggcgcag ctgggcagcc accgaggcct
     1801 gcaccagtcc atcgaagaat tccgggccaa gatcgagcgg gcacggagtg acgagggcca
     1861 gctctccccc gccacccggg gtgcctaccg tgactgcctg ggtcggctgg acctgcagta
     1921 cgccaagctg ctgaactcct ccaaggcccg cctcaggtcc ctggagagct tgcacagctt
     1981 tgtggcagcc gccactaagg agctaatgtg gctgaatgag aaggaggagg aggaggtggg
     2041 cttcgactgg agcgaccgca acaccaacat gaccgccaag aaggagagct actcggcgct
     2101 gatgcgggag ctggagctga aggagaagaa gatcaaggag ctccaaaatg ctggggaccg
     2161 gctgctgcgg gaggaccacc cggcccggcc cacggtggag tccttccagg cggccctgca
     2221 gacgcagtgg agctggatgc tacagctgtg ctgctgtatc gaggcacacc tgaaggagaa
     2281 cgctgcctac tttcagttct tctcagatgt gcgggaggcc gaggggcagt tgcagaagct
     2341 gcaggaggca ctgcgtagga aatacagttg tgatcgctcc gccaccgtca cccggctgga
     2401 ggacctgctg caggatgccc aggacgagaa ggaacagctg aacgagtaca agggccacct
     2461 ctcaggcctg gccaagcggg ccaaggccgt cgtgcagctg aagccccgcc acccagccca
     2521 ccccatgcgg ggccgcctgc ccctgctggc cgtgtgcgac tataagcagg tggaggtgac
     2581 tgtgcacaag ggtgacgagt gccagctggt gggccctgca cagccgtccc actggaaggt
     2641 gctcagcagc tccggcagcg aggccgccgt gccctccgtg tgcttcctgg tgcccccgcc
     2701 caaccaggag gcccaggagg ccgtcaccag gctggaggcc cagcaccagg ccctggtcac
     2761 gctgtggcac cagttgcacg tggacatgaa gagccttctg gcctggcaga gccttcgccg
     2821 cgacgtgcag ctcatccgct cctggtccct ggccacgttc cgcaccctga agccagagga
     2881 gcagcgccaa gccctgcaca gcctggagct gcactaccag gccttcctgc gggacagcca
     2941 ggacgcgggc ggcttcggac ccgaggaccg gctgatggct gagcgcgagt acggctcctg
     3001 cagccaccac taccagcagc tgctgcagag cctggaacag ggtgcacagg aagagtctcg
     3061 ctgccagcgc tgcatctccg agctcaaaga catccggctg cagctggagg cctgtgagac
     3121 gcgcaccgtg caccgcctgc ggctgccgct ggacaaagag ccggcacggg agtgtgccca
     3181 gcgcatcgcc gagcagcaga aggcacaggc agaggtggag gggctgggca agggggtcgc
     3241 ccggctctct gccgaggccg agaaggtctt ggccctacca gagccatcgc ctgcggcccc
     3301 cacgctgcgc tcggagctgg agctgacgct gggcaagctg gagcaggtcc gcagcctgtc
     3361 tgccatctac ctggagaagc tcaagaccat cagcctggtg atccgcggca cgcagggggc
     3421 cgaggaggtg ctcagggccc acgaggagca gctcaaggag gcccaggccg tgccggccac
     3481 cctcccggag ctcgaggcca ccaaggcctc tctgaagaag ctgcgggccc aggccgaggc
     3541 acagcagccc acgttcgacg ccctgcggga tgagctgcgg ggggcacagg aggtggggga
     3601 gcgactgcag cagcggcacg gggagcggga cgtggaggtg gagcgctggc gggagcgggt
     3661 cgcccagttg cttgagcgct ggcaggctgt gctggcccag accgacgtgc ggcagcgcga
     3721 gctcgagcaa ctgggccgcc agctgcgtta ctaccgcgag agtgcagacc ccttgggcgc
     3781 ctggctgcag gacgccaggc ggcggcagga gcagatccag gccatgccgc tggccgacag
     3841 ccaggctgtg cgggagcagc tgcggcagga gcaggccctg ctggaggaga tcgagcgcca
     3901 cggcgagaag gtcgaggagt gccagaggtt tgcgaaacag tacatcaacg ccatcaagga
     3961 ctatgaactc cagctggtga cgtacaaggc gcagcttgag ccggtggcct ccccggccaa
     4021 gaagcccaag gtccagtcgg gatcagagag tgtcatccag gagtacgtgg acctgcgtac
     4081 gcactacagc gagctgacca cactgacgag ccagtacatc aagttcatca gcgagactct
     4141 gcggcgcatg gaggaggagg agaggctggc tgagcagcag cgggcagagg agcgcgagcg
     4201 gctggccgag gtggaggccg cgctggagaa gcagcggcag ctggccgagg cgcacgccca
     4261 ggcaaaggca caggcggagc gggaggcgaa ggagctgcag cagcgcatgc aggaggaggt
     4321 ggtgcggcgg gaggaggcgg cggtggacgc gcagcagcag aagcgcagca ttcaggagga
     4381 gctgcagcag ctgcggcaga gctcggaggc ggagatccag gccaaggccc ggcaggcaga
     4441 ggcggctgag cgcagccggc tgcgcatcga ggaggagatc cgcgtggtgc gcctgcagtt
     4501 ggaggccacc gagcgccagc gtggcggggc tgagggggag ctgcaggcac tgcgtgcacg
     4561 ggcggaggag gctgaggcac aaaagcgaca ggcgcaggag gaggccgagc gcttgcggag
     4621 gcaggtgcag gacgagagcc agcgtaagcg gcaggcggag gtggagctgg cctcgcgcgt
     4681 gaaggccgag gccgaggcgg cgcgcgagaa gcagcgggcc ctgcaggccc tggaggagct
     4741 gcggctgcag gcggaggagg cggagcggcg cctgcggcag gccgaggtgg agcgagcgcg
     4801 gcaggtacag gtggccctgg agacggcgca gcgcagtgca gaggcggagc tgcagagcaa
     4861 acgcgcctcc ttcgccgaga agacggcaca gctggagcgc tccctgcagg aggaacacgt
     4921 ggctgtggca cagctgcggg aggaggctga gcggcgggca cagcagcagg ccgaggccga
     4981 gcgggcgcgc gaggaggcag agcgggagct ggagcgctgg cagctcaagg ccaacgaggc
     5041 gctacggctg cggctgcagg cggaggaggt ggcgcagcag aagagcctgg cgcaggccga
     5101 ggctgagaag cagaaggagg aggcggagcg cgaggcgcgg cggcgcggca aggcggagga
     5161 gcaggccgtc cggcagcggg agctggctga acaagagctg gagaagcagc ggcagctggc
     5221 ggaaggcacc gcgcagcagc gcctggccgc ggagcaggag ttgatccggc tgcgggccga
     5281 gacggagcag ggggagcagc agcggcagct gctggaggag gagctggccc ggctgcagcg
     5341 tgaggcggct gcagccacgc agaaacggca ggagctggaa gccgagctgg ccaaggtgcg
     5401 ggccgagatg gaggtgctgc tggccagcaa ggcgagggct gaggaggagt cgcgctccac
     5461 cagcgagaag tccaagcaga ggctggaggc cgaggccggc cggttccgcg agctggccga
     5521 ggaggccgcc cgcctgcgtg ccctggcgga agaggccaag cggcagcggc agctggccga
     5581 ggaagacgcg gcgcggcagc gggccgaggc ggagcgggtg cttgcggaga agctggccgc
     5641 catcggcgag gccacgcggc tcaagacgga ggcggagatc gcgctcaagg agaaggaggc
     5701 ggagaacgag cgcctgcggc ggctggcgga ggacgaggcc ttccagcggc ggcggctgga
     5761 ggagcaggcc gcgcaacaca aggctgacat cgaggagcgc ctggcccagc tgcgcaaggc
     5821 atcggacagc gagctggagc ggcagaaggg gctggtggag gacacgctga ggcagcggcg
     5881 gcaggtggag gaggagatcc tggcgctgaa ggcgagcttc gagaaggcgg ccgctggcaa
     5941 ggcggagctg gagctggagc tgggacgcat ccgcagcaac gcggaggaca cgctgcgcag
     6001 caaggagcag gccgagctgg aggctgcgag gcagcggcag ctggcggcgg aggaggagcg
     6061 gcggcgccgt gaggctgagg agcgcgtgca gaagagcctg gcggccgagg aggaggccgc
     6121 acggcagcgg aaggcggcgc tggaggaagt cgagcggctg aaagccaagg tggaggaggc
     6181 gcggcgcctg cgggagcgag cggagcagga gtcggcgcgg cagctgcagc tggcccagga
     6241 ggccgcccag aagcggctgc aggcggaaga gaaggcacac gccttcgcgg tgcagcagaa
     6301 ggagcaggag ctacagcaga cgctgcagca ggagcagagc gtgctggacc agctgcgcgg
     6361 cgaggcggag gcggcccggc gggcggctga ggaggcggag gaggcccggg tgcaggcgga
     6421 gcgtgaggcg gcgcagtccc ggcggcaggt ggaagaggcc gagcggctga agcagtcggc
     6481 agaggagcag gcacaggccc gggctcaggc acaggcggct gcagagaagc tgcgcaagga
     6541 ggccgagcaa gaggcggcgc ggcgggcaca ggcggagcag gcggccctgc ggcagaagca
     6601 ggcagctgac gcggagatgg agaagcataa gaaattcgcc gagcagacgc tgcggcagaa
     6661 ggcgcaggtg gagcaggagc tgacaacact gcggctgcag ctggaggaga ccgaccacca
     6721 gaagaacctg ctggacgagg agctgcagcg gctgaaggcg gaggccacgg aggccgcacg
     6781 ccagcgcagc caggtggagg aggagctctt ctcggtgcgc gtgcagatgg aggagctgag
     6841 caagctcaag gcacgcatcg aggctgagaa ccgcgcactc atcttgcgtg acaaggacaa
     6901 tacgcagcgc ttcctgcagg aggaggctga gaagatgaag caggtggcgg aggaggccgc
     6961 gcggctgagt gtggcggccc aagaggctgc gcgactgcgg cagctggcag aggaggacct
     7021 ggcacagcag cgggccttgg cagagaagat gctcaaggag aagatgcagg cggtgcagga
     7081 ggccacgcga ctcaaggctg aggcggaact gctgcagcag cagaaggagc ttgcgcagga
     7141 gcaggcgcgg cggctgcagg aggacaagga gcagatggcg cagcagctgg cggaggagac
     7201 gcagggcttc cagcggacgc tggaggccga gcggcagcgg cagctggaga tgagcgctga
     7261 ggctgagcgc ctcaagctgc gtgtggccga gatgagccga gcccaggccc gcgctgagga
     7321 ggacgcccag cgcttccgga agcaggcgga ggagatcggt gagaagctgc accgcacgga
     7381 gctcgccacc caggagaagg tgaccctggt gcagacactg gagatccagc gacagcagag
     7441 tgaccatgat gccgagcgcc tgcgggaggc catcgctgag ctggagcgtg agaaggagaa
     7501 gctccaacag gaggccaaac tgctgcagct caagtctgag gagatgcaga cggtgcagca
     7561 ggagcagctg ctgcaggaga cgcaggccct gcagcaaagc ttcctctctg aaaaggacag
     7621 cctgctacag cgggagcgct tcatcgagca ggagaaggcc aagctggagc agctcttcca
     7681 ggacgaggtg gccaaggcac agcagctgcg tgaggagcag cagcggcagc agcagcagat
     7741 ggagcaggaa cggcagcggc tggtggccag catggaggag gcgcggcggc ggcagcatga
     7801 ggccgaggag ggcgtgcggc gcaagcagga ggagctgcag cagctggagc agcagcggcg
     7861 gcagcaggag gagctgctgg ctgaggagaa ccagaggctg cgtgagcagc tgcagctcct
     7921 ggaggagcag caccgggccg cgctggcgca ctcagaggag gtcactgcct cgcaggtggc
     7981 tgccacaaag accctgccca atggccggga tgcacttgat ggccccgcgg cagaggcaga
     8041 gccggagcac agcttcgatg gcctgcggcg gaaggtgtca gctcagaggc tgcaggaggc
     8101 cggcatcctg agtgcggagg agctgcagcg gttggcgcag ggccacacca cggtggacga
     8161 gctcgcacgg cgggaagacg tgcgccacta cctgcagggc cgcagcagta tcgcagggct
     8221 gttgctgaag gccaccaatg agaagctgag tgtttacgcc gccctgcaga ggcagctgct
     8281 gagtcccggc acggccctca tcctgctgga ggcgcaggcg gcctcaggct tcctgctgga
     8341 ccctgtgcgg aaccggcggc tgaccgtcaa cgaggctgtg aaggagggtg tggtgggccc
     8401 cgagctgcac cacaagctgc tgtcggccga gcgcgccgtc actggctaca aggaccccta
     8461 cactggccag cagatctctc tcttccaagc catgcagaag ggcctcatcg tccgggagca
     8521 cggcatccgc ctgctggagg cccagatcgc cacgggcggc gttatcgacc ccgtgcacag
     8581 ccaccgcgtg cccgtggacg tggcctaccg gcgcggctac ttcgacgagg agatgaaccg
     8641 cgtcctggcg gaccccagcg acgacaccaa gggcttcttt gaccccaaca cgcacgagaa
     8701 cctcacgtac ctgcagctac tggagcgctg cgtggaggac cccgagacgg gcctgtgcct
     8761 tctgccactc acggataagg ctgccaaggg cggggagctg gtctacactg actccgaggc
     8821 ccgggacgtc tttgagaagg ccaccgtgtc tgcgccgttc ggcaagttcc agggcaagac
     8881 ggtgaccatt tgggagatca tcaactcgga atacttcacg gcagagcagc ggcgggacct
     8941 gctgcggcag ttccgcacgg gccggatcac agtggagaag atcatcaaga tcatcatcac
     9001 ggtggtggag gagcaggagc agaagggccg gctttgcttt gagggcctgc gcagcctggt
     9061 gccagccgcc gagctgctgg agagcagggt catcgaccgc gagctctacc agcagctgca
     9121 gcgaggtgag cgctctgtgc gagacgtagc cgaggtggac actgtgcggc gggctctccg
     9181 gggtgccaac gtcatcgcgg gtgtatggct ggaggaggcg gggcagaagc tgagtatcta
     9241 caatgccctg aagaaagacc tgctgccatc cgacatggcc gtggccctgt tggaagccca
     9301 ggccggcacc gggcacatca tcgaccccgc caccagcgcc cggctgaccg tggacgaggc
     9361 agtgcgtgct ggcctggtgg gccccgagtt tcatgagaag ctgctatcag ccgagaaggc
     9421 tgtgacaggg tacagggacc cctacacagg gcagagcgtc tccctgttcc aggccctgaa
     9481 gaagggcctc attccccggg agcagggcct gcgcctgttg gacgcccagc tgtccacggg
     9541 cggcatcgtg gaccccagca agagccaccg cgtgcccctg gatgtcgcct gcgcccgagg
     9601 ctgcctggat gaggagacca gcagggccct gtcggcacca agggccgacg ccaaggccta
     9661 cagtgacccc agcacagggg agccggccac ctacggcgag ctccagcagc ggtgccggcc
     9721 cgaccagctg accgggctga gcctgctgcc gctctcagaa aaggctgctc gggcccggca
     9781 ggaggagctc tactcagagc tgcaggcccg tgagaccttt gaaaagaccc cggttgaggt
     9841 ccccgtgggt ggcttcaagg gcaggacggt gacggtgtgg gagctcatca gctctgagta
     9901 cttcactgcg gagcagcggc aggagctgtt gcgtcagttc cgcacgggca aggtcaccgt
     9961 ggagaaggtc atcaagattc tcattaccat cgtggaggag gtggagaccc tgcggcagga
    10021 gaggctgtcc ttcagcggcc tccgtgcccc tgtgccagcc agcgagctcc tggcttccgg
    10081 ggtcctcagc agagcccagt ttgagcagct caaggacggc aagacgacgg tcaaggacct
    10141 ttcggagctg ggctccgtgc ggacgctgct gcagggcagt ggctgcctcg ccggcatcta
    10201 cctggaggac accaaggaga aggtgtccat ctacgaggcc atgcgccggg gcctgctgag
    10261 agccacaacg gctgcgctcc tgctggaggc gcaggcggcc actggcttcc tggtggaccc
    10321 cgtgcggaac cagcgcctgt atgtccacga ggccgtgaag gcgggcgtgg tgggccccga
    10381 gcttcacgag cagctgctgt ctgccgagaa ggccgtcacc ggctacagag acccctactc
    10441 gggcagcacc atctccctct tccaggccat gcagaagggc ctggttctcc ggcagcacgg
    10501 catccgcctg ctggaggccc agatcgccac gggcggcatc atcgaccccg tgcacagcca
    10561 ccgcgtgcct gtggacgtgg cctaccagcg cggctacttc agtgaggaga tgaaccgcgt
    10621 cctggcggac cccagcgacg acaccaaggg cttctttgac cccaacacgc atgagaacct
    10681 cacgtacagg cagctgctgg agcggtgcgt ggaggacccc gagacgggct tgcgccttct
    10741 gccactgaaa ggggcggaga aggctgaggt ggtggagacc acgcaggtgt acactgagga
    10801 ggagacaaga agggcatttg aagagacaca gatcgacatt cccggcggcg gcagccacgg
    10861 cggctccacc atgtccctgt gggaggtgat gcagtcggac ctgatccccg aggagcagcg
    10921 ggcccagctg atggctgact tccaggccgg ccgggtgacc aaggaacgca tgatcatcat
    10981 catcatcgag atcattgaga agacagagat catccgccag cagggtctgg cctcctacga
    11041 ctacgtgcgc cgccgcctca cggctgagga cctgttcgag gctcggatca tctctctcga
    11101 gacctacaac ctgctccggg agggcaccag gagcctccgt gaggctctcg aggcggagtc
    11161 cgcctggtgc tacctctatg gcacgggctc cgtggctggt gtctacctgc ccggttccag
    11221 gcagacactg agcatctacc aggctctcaa gaaagggctg ctgagtgccg aggtggcccg
    11281 cctgctgctg gaggcacagg cagccacagg cttcctgctg gacccggtga agggggagcg
    11341 gctgactgtg gatgaggctg tgcggaaggg cctcgtgggg cccgagctgc acgaccgcct
    11401 gctctcggct gagcgggcgg tcaccggcta ccgtgacccc tacaccgagc agaccatctc
    11461 gctcttccag gccatgaaga aggagctgat ccctactgag gaggccctgc ggctgctgga
    11521 tgcccagctg gccaccggcg gcatcgtgga cccccgcctg ggcttccacc ttcccctgga
    11581 ggtggcttac cagcgtggct acctcaacaa ggacacgcac gaccagctgt cagagcccag
    11641 cgaggtgcgc agctacgtgg acccgtccac cgacgagcgc ctcagctaca cgcagctgct
    11701 caggcggtgc cgtcgtgacg acggcaccgg ccagctgctc ctgccactgt cggacgcccg
    11761 caagctgacc ttccgtggcc tgcggaagca gatcaccatg gaggagctgg tgcgctcgca
    11821 ggtcatggac gaggccacgg cgctgcagct gcgggagggc ctgacctcca tcgaggaggt
    11881 caccaagaac ttgcagaagt tcctggaagg caccagctgc atcgctggtg tcttcgtgga
    11941 cgccaccaag gaacggctct cggtgtacca ggccatgaag aagggcatca tccgccccgg
    12001 cacagccttt gagctcctgg aggcgcaggc ggccaccggt tacgtcatcg accccatcaa
    12061 gggactgaag ctgacggtgg aggaggctgt gcgtatgggc attgtgggcc ccgagttcaa
    12121 ggacaagctg ctgtcggccg agcgcgccgt cactgggtac aaggacccct actctgggaa
    12181 gctcatctcc ctcttccagg ccatgaagaa gggcctgatc ctgaaggacc atggcatccg
    12241 cctgctggag gcccagatcg ccacgggcgg catcatcgac cctgaggaga gccaccggct
    12301 gcccgtggag gtggcctaca agcgcggcct cttcgatgag gagatgaacg agatcctgac
    12361 cgacccctcg gacgacacca agggcttctt tgaccctaac acggaggaga acctcaccta
    12421 cctgcagctg atggagcgtt gtatcactga cccccagacg ggcctgtgtc tcttgccgct
    12481 gaaggagaag aagcgggagc ggaagacgtc ctccaagtcc tccgtgcgca agcgccgagt
    12541 ggtcatcgtg gaccccgaga cgggcaagga gatgtcagtg tacgaggcct accgcaaggg
    12601 cctgattgac caccagacgt acctggagct gtccgagcag gagtgcgagt gggaggagat
    12661 caccatctcc tcctcggacg gcgtggtcaa gtccatgatc atcgaccgcc gctccgggcg
    12721 ccagtacgac atcgatgatg ccatcgccaa gaacctcatc gaccgctcgg cactggacca
    12781 gtaccgcgcc ggcacgctct ccatcaccga gttcgccgac atgctctcgg gcaacgccgg
    12841 tggtttccgc tcccgttcct cctcggtggg atcctcctcc tcctacccca tcagccccgc
    12901 cgtctccagg acccagctgg cctcctggtc agaccccact gaggagacgg gccccgtggc
    12961 tggcatcctg gacacggaga cgctggagaa ggtgtccatc accgaggcca tgcaccggaa
    13021 cctggtggat aacatcacgg ggcagcggct gctggaggcg caggcctgca ccgggggcat
    13081 catcgacccc agcaccggtg agcgcttccc tgtcaccgac gccgtcaaca agggcctggt
    13141 ggacaagatc atggtggacc gcatcaacct ggcccagaag gccttctgcg gcttcgagga
    13201 cccacgcacc aagaccaaga tgtcggccgc ccaggccctg aagaagggct ggctctacta
    13261 cgaggccggc cagcgcttcc tggaggtgca gtacctgacc ggcggcttga tcgagcccga
    13321 cacgccgggc cgcgtgcccc tggacgaggc cctgcagcgc ggcacggtgg acgcccgcac
    13381 cgcacagaag ctgcgtgacg tgggcgccta ctccaagtac ctcacctgcc ctaagaccaa
    13441 gctcaagatc tcctataagg acgcgctgga ccgcagcatg gtggaggagg gcacggggct
    13501 gcggctgctg gaggctgccg cgcagtccac caagggctac tacagcccct acagcgtcag
    13561 cggctccggc tctaccgctg gctcccgcac cggctcgcgc accggctccc gggccggctc
    13621 ccgccgcggc agctttgacg ccaccggctc cggcttctcc atgaccttct cttcatcctc
    13681 ctactcctcc tcgggctacg gccgccgcta cgcctcgggg tcctcggcct ccctgggggg
    13741 ccctgagtct gccgtggcct gaggctgcct gcgcccaccc cgctctgcat gcggcccagc
    13801 ccggctccca ccgaggcgcg ggggccgttt tcaacgctta aaggtgtctt cctcccaagt
    13861 ggtgcctaaa gtttaaccaa aaagaccaga ctaatatatt aatatatatc tgctgtccag
    13921 acagcctgta tcttggggga cagggctggc ccagccctgc tggccgcctc accccctcgg
    13981 gtctcctcac tcccttctac ctgccactca cacagccagg tgccttggag ggtcccaagc
    14041 tgggccccag cccaccctcc tgtcttccca gggtagcccg cctgccagtc ctagctgcac
    14101 agggcagctg ggcccaaccc tgtctgtaga gggccctggt gtttctagca ctggcctgca
    14161 cggtgggcct tgctggggac ggggggcccc agtcagcctc tctcccagtc tacccagaga
    14221 agccccttcc ccatgggaag acgaggccct cgggcccagc ccccacagtg ctgtctgatc
    14281 tgtgctttcc agctcacccc ccacactcac tcctgagacc cctggcctcc ggcgtcagcc
    14341 tccagcctct gttcccctag taagtgcctt ccatgtcggc ctctaacccc aggccccgag
    14401 gacccagacc cagtggggag gcggacgttc cagccggcat ggctgggaac tgcagacctg
    14461 tcctcctggt gggtccaggg gcccctccag cttgtggagc cccacactgg ggtgccgcct
    14521 gcccgtctct ctcccatgga gccccagccc cctttgggcc cagggacacc agccaggctc
    14581 tgtgctgacc ctcctgttgc acccagccct ggtctcagca gcgaccaccc ctgcctccac
    14641 cctctgagct ttgcatgttc cactaacccc gggcgggtgg caggtggagg tgtcaggctg
    14701 ctggcgcctc tgcaagggca gaacactaac ctgaccgtgg gcggggcctt gcggtatccg
    14761 cccccaataa aagcaattcc aacctt
//
