LOCUS       XM_047425353            2649 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens plasminogen activator, urokinase (PLAU),
            transcript variant X1, mRNA.
ACCESSION   XM_047425353
VERSION     XM_047425353.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000010.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2649
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     gene            1..2649
                     /gene="PLAU"
                     /gene_synonym="ATF; BDPLT5; QPD; u-PA; UPA; URK"
                     /note="plasminogen activator, urokinase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 6 mRNAs, 66 ESTs, 551 long SRA reads, 11 Proteins, and
                     99% coverage of the annotated genomic feature by RNAseq
                     alignments, including 115 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5328"
                     /db_xref="HGNC:HGNC:9052"
                     /db_xref="MIM:191840"
     CDS             425..1720
                     /gene="PLAU"
                     /gene_synonym="ATF; BDPLT5; QPD; u-PA; UPA; URK"
                     /codon_start=1
                     /product="urokinase-type plasminogen activator isoform X1"
                     /protein_id="XP_047281309.1"
                     /db_xref="GeneID:5328"
                     /db_xref="HGNC:HGNC:9052"
                     /db_xref="MIM:191840"
                     /translation="MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKY
                     FSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQ
                     TYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSP
                     PEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCW
                     VISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDI
                     ALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKM
                     TVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTG
                     IVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL"
ORIGIN      
        1 acagtgcgga gaccgcagcc ccggagcccg ggccagggtc cacctgtccc cgcagcgccg
       61 gctcgcgccc tcctgccgca gccaccggtg agtgccgcgg tcctgagatc cccgggccgg
      121 atgcgcggcg gccccagctc ccgagcgtct gcctcccccg ccctgggctg cccgggctcc
      181 ctgggctccc cggcggctgc acggagtcaa ggcgccccgt cccgggcgtc ccccgcgggt
      241 gccgatccag gctgcccgga gtccggagcc cagagaggag agagacagct ggggagcctg
      301 gtcaccgcgg gcatctcccc tgcgctgcag tcgcccgcct ggcctgcctt cccgttcctc
      361 cgcctcttgc cctgacttct ccttcctttg cagagccgcc gtctagcgcc ccgacctcgc
      421 caccatgaga gccctgctgg cgcgcctgct tctctgcgtc ctggtcgtga gcgactccaa
      481 aggcagcaat gaacttcatc aagttccatc gaactgtgac tgtctaaatg gaggaacatg
      541 tgtgtccaac aagtacttct ccaacattca ctggtgcaac tgcccaaaga aattcggagg
      601 gcagcactgt gaaatagata agtcaaaaac ctgctatgag gggaatggtc acttttaccg
      661 aggaaaggcc agcactgaca ccatgggccg gccctgcctg ccctggaact ctgccactgt
      721 ccttcagcaa acgtaccatg cccacagatc tgatgctctt cagctgggcc tggggaaaca
      781 taattactgc aggaacccag acaaccggag gcgaccctgg tgctatgtgc aggtgggcct
      841 aaagctgctt gtccaagagt gcatggtgca tgactgcgca gatggaaaaa agccctcctc
      901 tcctccagaa gaattaaaat ttcagtgtgg ccaaaagact ctgaggcccc gctttaagat
      961 tattggggga gaattcacca ccatcgagaa ccagccctgg tttgcggcca tctacaggag
     1021 gcaccggggg ggctctgtca cctacgtgtg tggaggcagc ctcatcagcc cttgctgggt
     1081 gatcagcgcc acacactgct tcattgatta cccaaagaag gaggactaca tcgtctacct
     1141 gggtcgctca aggcttaact ccaacacgca aggggagatg aagtttgagg tggaaaacct
     1201 catcctacac aaggactaca gcgctgacac gcttgctcac cacaacgaca ttgccttgct
     1261 gaagatccgt tccaaggagg gcaggtgtgc gcagccatcc cggactatac agaccatctg
     1321 cctgccctcg atgtataacg atccccagtt tggcacaagc tgtgagatca ctggctttgg
     1381 aaaagagaat tctaccgact atctctatcc ggagcagctg aaaatgactg ttgtgaagct
     1441 gatttcccac cgggagtgtc agcagcccca ctactacggc tctgaagtca ccaccaaaat
     1501 gctgtgtgct gctgacccac agtggaaaac agattcctgc cagggagact cagggggacc
     1561 cctcgtctgt tccctccaag gccgcatgac tttgactgga attgtgagct ggggccgtgg
     1621 atgtgccctg aaggacaagc caggcgtcta cacgagagtc tcacacttct taccctggat
     1681 ccgcagtcac accaaggaag agaatggcct ggccctctga gggtccccag ggaggaaacg
     1741 ggcaccaccc gctttcttgc tggttgtcat ttttgcagta gagtcatctc catcagctgt
     1801 aagaagagac tgggaagata ggctctgcac agatggattt gcctgtgcca cccaccaggg
     1861 cgaacgacaa tagctttacc ctcaggcata ggcctgggtg ctggctgccc agacccctct
     1921 ggccaggatg gaggggtggt cctgactcaa catgttactg accagcaact tgtctttttc
     1981 tggactgaag cctgcaggag ttaaaaaggg cagggcatct cctgtgcatg ggtgaaggga
     2041 gagccagctc ccccgacggt gggcatttgt gaggcccatg gttgagaaat gaataatttc
     2101 ccaattagga agtgtaacag ctgaggtctc ttgagggagc ttagccaatg tgggagcagc
     2161 ggtttgggga gcagagacac taacgacttc agggcagggc tctgatattc catgaatgta
     2221 tcaggaaata tatatgtgtg tgtatgtttg cacacttgtg tgtgggctgt gagtgtaagt
     2281 gtgagtaaga gctggtgtct gattgttaag tctaaatatt tccttaaact gtgtggactg
     2341 tgatgccaca cagagtggtc tttctggaga ggttataggt cactcctggg gcctcttggg
     2401 tcccccacgt gacagtgcct gggaatgtat tattctgcag catgacctgt gaccagcact
     2461 gtctcagttt cactttcaca tagatgtccc tttcttggcc agttatccct tccttttagc
     2521 ctagttcatc caatcctcac tgggtggggt gaggaccact cctgtacact gaatatttat
     2581 atttcactat ttttatttat atttttgtaa ttttaaataa aagtgatcaa taaaatgtga
     2641 tttttctga
//
