LOCUS       NM_013355               3393 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens protein kinase N3 (PKN3), transcript variant 1, mRNA.
ACCESSION   NM_013355
VERSION     NM_013355.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3393)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 3393)
  AUTHORS   Dibus,M., Brabek,J. and Rosel,D.
  TITLE     A Screen for PKN3 Substrates Reveals an Activating Phosphorylation
            of ARHGAP18
  JOURNAL   Int J Mol Sci 21 (20), 7769 (2020)
   PUBMED   33092266
  REMARK    GeneRIF: A Screen for PKN3 Substrates Reveals an Activating
            Phosphorylation of ARHGAP18.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3393)
  AUTHORS   Buljan,M., Ciuffa,R., van Drogen,A., Vichalkovski,A., Mehnert,M.,
            Rosenberger,G., Lee,S., Varjosalo,M., Pernas,L.E., Spegg,V.,
            Snijder,B., Aebersold,R. and Gstaiger,M.
  TITLE     Kinase Interaction Network Expands Functional and Disease Roles of
            Human Kinases
  JOURNAL   Mol Cell 79 (3), 504-520 (2020)
   PUBMED   32707033
REFERENCE   4  (bases 1 to 3393)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 3393)
  AUTHORS   Gemperle,J., Dibus,M., Koudelkova,L., Rosel,D. and Brabek,J.
  TITLE     The interaction of p130Cas with PKN3 promotes malignant growth
  JOURNAL   Mol Oncol 13 (2), 264-289 (2019)
   PUBMED   30422386
  REMARK    GeneRIF: a novel interaction of p130Cas with Ser/Thr kinase PKN3,
            is reported.
REFERENCE   6  (bases 1 to 3393)
  AUTHORS   Humphray,S.J., Oliver,K., Hunt,A.R., Plumb,R.W., Loveland,J.E.,
            Howe,K.L., Andrews,T.D., Searle,S., Hunt,S.E., Scott,C.E.,
            Jones,M.C., Ainscough,R., Almeida,J.P., Ambrose,K.D., Ashwell,R.I.,
            Babbage,A.K., Babbage,S., Bagguley,C.L., Bailey,J., Banerjee,R.,
            Barker,D.J., Barlow,K.F., Bates,K., Beasley,H., Beasley,O.,
            Bird,C.P., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.,
            Burrill,W., Burton,J., Carder,C., Carter,N.P., Chapman,J.C.,
            Chen,Y., Clarke,G., Clark,S.Y., Clee,C.M., Clegg,S., Collier,R.E.,
            Corby,N., Crosier,M., Cummings,A.T., Davies,J., Dhami,P., Dunn,M.,
            Dutta,I., Dyer,L.W., Earthrowl,M.E., Faulkner,L., Fleming,C.J.,
            Frankish,A., Frankland,J.A., French,L., Fricker,D.G., Garner,P.,
            Garnett,J., Ghori,J., Gilbert,J.G., Glison,C., Grafham,D.V.,
            Gribble,S., Griffiths,C., Griffiths-Jones,S., Grocock,R., Guy,J.,
            Hall,R.E., Hammond,S., Harley,J.L., Harrison,E.S., Hart,E.A.,
            Heath,P.D., Henderson,C.D., Hopkins,B.L., Howard,P.J., Howden,P.J.,
            Huckle,E., Johnson,C., Johnson,D., Joy,A.A., Kay,M., Keenan,S.,
            Kershaw,J.K., Kimberley,A.M., King,A., Knights,A., Laird,G.K.,
            Langford,C., Lawlor,S., Leongamornlert,D.A., Leversha,M., Lloyd,C.,
            Lloyd,D.M., Lovell,J., Martin,S., Mashreghi-Mohammadi,M.,
            Matthews,L., McLaren,S., McLay,K.E., McMurray,A., Milne,S.,
            Nickerson,T., Nisbett,J., Nordsiek,G., Pearce,A.V., Peck,A.I.,
            Porter,K.M., Pandian,R., Pelan,S., Phillimore,B., Povey,S.,
            Ramsey,Y., Rand,V., Scharfe,M., Sehra,H.K., Shownkeen,R.,
            Sims,S.K., Skuce,C.D., Smith,M., Steward,C.A., Swarbreck,D.,
            Sycamore,N., Tester,J., Thorpe,A., Tracey,A., Tromans,A.,
            Thomas,D.W., Wall,M., Wallis,J.M., West,A.P., Whitehead,S.L.,
            Willey,D.L., Williams,S.A., Wilming,L., Wray,P.W., Young,L.,
            Ashurst,J.L., Coulson,A., Blocker,H., Durbin,R., Sulston,J.E.,
            Hubbard,T., Jackson,M.J., Bentley,D.R., Beck,S., Rogers,J. and
            Dunham,I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
REFERENCE   7  (bases 1 to 3393)
  AUTHORS   Shibata,H., Oishi,K., Yamagiwa,A., Matsumoto,M., Mukai,H. and
            Ono,Y.
  TITLE     PKNbeta interacts with the SH3 domains of Graf and a novel Graf
            related protein, Graf2, which are GTPase activating proteins for
            Rho family
  JOURNAL   J Biochem 130 (1), 23-31 (2001)
   PUBMED   11432776
REFERENCE   8  (bases 1 to 3393)
  AUTHORS   Oishi,K., Takahashi,M., Mukai,H., Banno,Y., Nakashima,S.,
            Kanaho,Y., Nozawa,Y. and Ono,Y.
  TITLE     PKN regulates phospholipase D1 through direct interaction
  JOURNAL   J Biol Chem 276 (21), 18096-18101 (2001)
   PUBMED   11259428
REFERENCE   9  (bases 1 to 3393)
  AUTHORS   Oishi,K., Mukai,H., Shibata,H., Takahashi,M. and Ona,Y.
  TITLE     Identification and characterization of PKNbeta, a novel isoform of
            protein kinase PKN: expression and arachidonic acid dependency are
            different from those of PKNalpha
  JOURNAL   Biochem Biophys Res Commun 261 (3), 808-814 (1999)
   PUBMED   10441506
REFERENCE   10 (bases 1 to 3393)
  AUTHORS   Amano,M., Mukai,H., Ono,Y., Chihara,K., Matsui,T., Hamajima,Y.,
            Okawa,K., Iwamatsu,A. and Kaibuchi,K.
  TITLE     Identification of a putative target for Rho as the serine-threonine
            kinase protein kinase N
  JOURNAL   Science 271 (5249), 648-650 (1996)
   PUBMED   8571127
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL441992.17.
            
            On Nov 23, 2018 this sequence version replaced NM_013355.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062558.1, AB019692.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2142680
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000291906.5/ ENSP00000291906.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-437               AL441992.17        3089-3525
            438-678             AL441992.17        5889-6129
            679-824             AL441992.17        6320-6465
            825-936             AL441992.17        7299-7410
            937-1064            AL441992.17        7482-7609
            1065-1248           AL441992.17        7808-7991
            1249-1395           AL441992.17        13638-13784
            1396-1505           AL441992.17        13864-13973
            1506-1649           AL441992.17        14085-14228
            1650-1725           AL441992.17        14632-14707
            1726-1894           AL441992.17        14783-14951
            1895-1997           AL441992.17        15148-15250
            1998-2065           AL441992.17        15384-15451
            2066-2129           AL441992.17        15758-15821
            2130-2221           AL441992.17        15955-16046
            2222-2398           AL441992.17        17333-17509
            2399-2461           AL441992.17        18911-18973
            2462-2538           AL441992.17        19135-19211
            2539-2681           AL441992.17        20272-20414
            2682-2789           AL441992.17        20496-20603
            2790-2870           AL441992.17        20789-20869
            2871-3393           AL441992.17        20980-21502
FEATURES             Location/Qualifiers
     source          1..3393
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.11"
     gene            1..3393
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /note="protein kinase N3"
                     /db_xref="GeneID:29941"
                     /db_xref="HGNC:HGNC:17999"
                     /db_xref="MIM:610714"
     exon            1..437
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             414..3083
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /EC_number="2.7.11.13"
                     /note="isoform 1 is encoded by transcript variant 1;
                     serine/threonine-protein kinase N3; protein kinase
                     PKN-beta; protein-kinase C-related kinase 3"
                     /codon_start=1
                     /product="serine/threonine-protein kinase N3 isoform 1"
                     /protein_id="NP_037487.2"
                     /db_xref="CCDS:CCDS6908.1"
                     /db_xref="GeneID:29941"
                     /db_xref="HGNC:HGNC:17999"
                     /db_xref="MIM:610714"
                     /translation="MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVA
                     TDRRHLGHVQQLLRSSNRRLEQLHGELRELHARILLPGPGPGPAEPVASGPRPWAEQL
                     RARHLEALRRQLHVELKVKQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLR
                     MKISSLEASGSPEPGPELLAEELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEA
                     QAQLQESSQKLDLLRLALEQLLEQLPPAHPLRSRVTRELRAAVPGYPQPSGTPVKPTA
                     LTGTLQVRLLGCEQLLTAVPGRSPAAALASSPSEGWLRTKAKHQRGRGELASEVLAVL
                     KVDNRVVGQTGWGQVAEQSWDQTFVIPLERARELEIGVHWRDWRQLCGVAFLRLEDFL
                     DNACHQLSLSLVPQGLLFAQVTFCDPVIERRPRLQRQERIFSKRRGQDFLRASQMNLG
                     MAAWGRLVMNLLPPCSSPSTISPPKGCPRTPTTLREASDPATPSNFLPKKTPLGEEMT
                     PPPKPPRLYLPQEPTSEETPRTKRPHMEPRTRRGPSPPASPTRKPPRLQDFRCLAVLG
                     RGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCTGHPFLLS
                     LLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQARFYVACVVLGLQFLHEKKIIY
                     RDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAV
                     DWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCP
                     EKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFTGLP
                     PALTPPAPHSLLTARQQAAFRDFDFVSERFLEP"
     exon            438..678
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            679..824
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            825..936
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1064
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1248
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1395
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1505
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1506..1649
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1725
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1894
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..1997
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2065
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2129
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2221
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2222..2398
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2399..2461
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2462..2538
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2539..2681
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2682..2789
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2790..2870
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..3393
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3376..3381
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /note="hexamer: ATTAAA"
     polyA_site      3393
                     /gene="PKN3"
                     /gene_synonym="UTDP4-1"
                     /note="major polyA site"
ORIGIN      
        1 atccctgtcc ctaactggcc ggctcccgcg ggcgcgcggc ggggaaggcc agaggacctg
       61 ggcgcgggcg atgtgcctcc tgagcgtcca aaccgggggt gaggcgcggt cacgcccagc
      121 gggaaccgca ggcgccgaag cccgggtact gggcccagaa tcccgcggaa ttttggatcc
      181 gagggaggcg ctggggcgcg ggacctcggg cgtggggtcc cgggcgctgg atcggcgcgg
      241 acgggaggcg gcgctggtcc cgcgggccag cgggtctcgg gagggggcgc ccgatcccgc
      301 gtctccggcg ccgcttcccg ggaagtttca agtttgaaag tcctggcgga gggtctgcgg
      361 cttccgggac cggagtggct gagagaaggg ccccaagcgg ccggagcggc gccatggagg
      421 agggggcgcc gcggcagcct gggccgagcc agtggccccc agaggatgag aaggaggtga
      481 tccgccgggc catccagaaa gagctgaaga tcaaggaggg ggtggagaac ctgcggcgcg
      541 tggccacaga ccgccgccac ttgggccatg tgcagcagct gctgcggtcc tccaaccgcc
      601 gcctggagca gctgcatggc gagctgcggg agctgcacgc ccgaatcctg ctgcccggcc
      661 ctgggcctgg cccagctgag cctgtggcct caggaccccg gccgtgggca gagcagctca
      721 gggctcggca cctagaggct ctccggaggc agctgcatgt ggagctgaag gtgaagcagg
      781 gggctgagaa catgacccac acgtgcgcca gtggcacccc caaggagagg aagctcctgg
      841 cagctgccca gcagatgctg cgggacagcc agctgaaggt ggccctgctg cggatgaaga
      901 tcagcagcct ggaggccagt gggtccccgg agccagggcc tgagctgctg gcggaggagc
      961 tacagcatcg actgcacgtt gaggcagctg tggctgaggg cgccaagaac gtggtgaaac
     1021 tgcttagtag ccggagaaca caggaccgca aggcactggc tgaggcccag gcccagctac
     1081 aggagtcctc tcagaaactg gacctcctgc gcctggcctt ggagcagctg ctggagcaac
     1141 tgcctcctgc ccaccctttg cgcagcagag tgacccgaga gttgcgggct gcggtgcctg
     1201 gataccccca gccttcaggg acacctgtga agcccaccgc cctaacaggg acactgcagg
     1261 tccgcctcct gggctgtgaa cagttgctga cagccgtgcc tgggcgctcc ccagcggccg
     1321 cactggccag cagcccctcc gagggctggc ttcggaccaa ggccaagcac cagcgtggcc
     1381 gaggcgagct tgccagcgag gtgctggctg tgctaaaggt ggacaaccgt gttgtggggc
     1441 agacgggctg ggggcaggtg gccgaacagt cctgggacca gacctttgtc atcccactgg
     1501 agcgagcccg tgagctggag attggggtac actggcggga ctggcggcag ctatgtggcg
     1561 tggccttcct gagacttgag gacttcctgg acaatgcctg tcaccaactg tccctcagcc
     1621 tggtaccgca gggactgctt tttgcccagg tgaccttctg cgatcctgtc attgagaggc
     1681 ggccccggct gcagaggcag gaacgcatct tctctaaacg cagaggccag gacttcctga
     1741 gggcttcgca gatgaacctc ggcatggcgg cctgggggcg cctcgtcatg aacctgctgc
     1801 ccccctgcag ctccccgagc acaatcagcc cccctaaagg atgccctcgg accccaacaa
     1861 cactgcgaga ggcctctgac cctgccactc ccagtaattt cctgcccaag aagaccccct
     1921 tgggtgaaga gatgacaccc ccacccaagc ccccacgcct ctacctcccc caggagccaa
     1981 catccgagga gactccgcgc accaaacgtc cccatatgga gcctaggact cgacgtgggc
     2041 catctccacc agcctccccc accaggaaac cccctcggct tcaggacttc cgctgcttag
     2101 ctgtgctggg ccggggacac tttgggaagg tcctcctggt ccagttcaag gggacaggga
     2161 aatactacgc catcaaagca ctgaagaagc aggaggtgct cagccgggac gagatagaga
     2221 gcctgtactg cgagaagcgg atcctggagg ctgtgggctg cacagggcac cctttcctgc
     2281 tctccctcct tgcctgcttc cagacctcca gccatgcctg ctttgtgact gagtttgtgc
     2341 ctggtggtga cctcatgatg cagatccacg aggatgtctt ccccgagccc caggcccgct
     2401 tctacgtggc ttgtgttgtc ctggggctgc agttcttaca cgagaagaag atcatttaca
     2461 gggacctgaa gttggataac cttctgctgg atgcccaggg attcctgaag atcgcagact
     2521 ttggactctg caaggaaggg atcggcttcg gggaccggac tagcaccttc tgtggcaccc
     2581 cggagttcct ggctcccgag gtgctgaccc aggaggcata cacacgggct gtggactggt
     2641 gggggctggg tgtgctgctc tacgagatgc tggtgggtga gtgcccgttc ccaggggaca
     2701 cagaggaaga ggtgtttgac tgcatcgtca acatggacgc cccctacccc ggctttctgt
     2761 cggtgcaagg gcttgagttc attcagaagc tcctccagaa gtgcccggag aagcgcctcg
     2821 gggcaggtga gcaggatgcc gaggagatca aggtccagcc attcttcagg accaccaact
     2881 ggcaagccct gctcgcccgc accatccagc cccccttcgt gcctaccctg tgtggccctg
     2941 cggacctgcg ctactttgag ggcgagttca cagggctgcc gcctgccctg accccacctg
     3001 caccccacag cctcctcact gcccgccaac aggccgcctt ccgggacttc gactttgtgt
     3061 cagagcgatt cctggaaccc tgagggcatc tcctggcacc tctgtcccct tcccccacag
     3121 actgttagag cctctgctcg ttcacccgtg cgccctgcct ggaggtccag gccttgctgg
     3181 gtacttctga gcccttggga ttcaaagtgg cagccatggg gccactgttg tgggctttgc
     3241 tcagtgtcac tgggcaaagt gtgtcccttc cccctccagc tcgccctctt ctacctccca
     3301 gcgagacctg gcccagaaag ggtgccgcag caaggagtga tatggtttgt ctttttaaga
     3361 ctggacttgc tttatattaa atttgtaaaa gtg
//
