LOCUS       XM_011514683           15629 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens PKHD1 ciliary IPT domain containing
            fibrocystin/polyductin (PKHD1), transcript variant X7, mRNA.
ACCESSION   XM_011514683
VERSION     XM_011514683.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011514683.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15629
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..15629
                     /gene="PKHD1"
                     /gene_synonym="ARPKD; FCYT; FPC; PCYT; PKD4; TIGM1"
                     /note="PKHD1 ciliary IPT domain containing
                     fibrocystin/polyductin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 mRNAs, 8 ESTs, 31 long
                     SRA reads, 3 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 8 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:5314"
                     /db_xref="HGNC:HGNC:9016"
                     /db_xref="MIM:606702"
     CDS             265..11847
                     /gene="PKHD1"
                     /gene_synonym="ARPKD; FCYT; FPC; PCYT; PKD4; TIGM1"
                     /codon_start=1
                     /product="fibrocystin isoform X6"
                     /protein_id="XP_011512985.1"
                     /db_xref="GeneID:5314"
                     /db_xref="HGNC:HGNC:9016"
                     /db_xref="MIM:606702"
                     /translation="MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDG
                     LELGVLYPNNGSQLEIHLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHE
                     GLYFLEAYFGGQLVSSPNPGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWII
                     TGRLETFDFDAEYIDSPVILEAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVE
                     GDYIGSQNVSFSVFNKGKSMVHKKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTN
                     ITITGDFFDNSAQVTIAGIPCDIRHVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEV
                     GDAVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNYTFWI
                     QADSQASLHFSWSEEPRTKVKVASISVGTADWFDSWEQNRDEGTWQQKTPKLELLGGA
                     MYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQVLNV
                     SGRGNFFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWSNILLRLGFERGP
                     EVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYRLDQYTHLCLAYKGHMNKI
                     LKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDCTDLWETCVRCFGDLQPPPANSP
                     VLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSGTARPGGNLVESVSVVGSPPV
                     YSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQRRQRTSPPLGGHFRIQLPN
                     TVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCYEHVWTLSWSTQI
                     GDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATANQHTQVVVRVNDVP
                     AHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQFLQVTVNKTSCK
                     VIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPRLDMVEPSRAA
                     DIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDGRIVNVTVI
                     RGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLDVEVHVQ
                     DALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFSIEPC
                     CGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDAGA
                     PTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVG
                     GSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQNFSLHGGSLLT
                     IEGTGLRGQNTTSVYIDQQTCLTVNIGAELIRCIVPTGNGSVALEIEVDGLWYHIGVI
                     GYNKAFTPELISISQSDDILTFAVAQISGAANIDIFIGMSPCVGVSGNHTVLQCVVPS
                     LPAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFGCLGGRLVHVFGAGFSPGNVS
                     AAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKREEDSCEAARHTYVQCDLTVA
                     MATEQLLESWPYLYICEESSQCLFVPDHWAESMFPSFSGLFISPKLERDEVLIYNSSC
                     NITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNFSLQFCRRWSRTHSWFPERLP
                     QDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGPIELRAHAILVSDGGELRI
                     GSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTCLRATAH
                     ALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSH
                     NFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYS
                     MSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSLTLVGAMRESF
                     IQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKD
                     DWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAGYGYFFH
                     LMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWESAGGA
                     QIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIKTP
                     KRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPH
                     AAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGL
                     ANTPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSL
                     QYSATFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNS
                     QLRQLTYLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGY
                     NNTIPGPGDDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGE
                     LKVGTLENPLEKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSW
                     THLGADIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYER
                     LKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSG
                     VLQLLNVEIQNFGSPLYSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNI
                     VFGTAGHGIDLEGQAYTVTNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSE
                     RLGFHIRGHKCSSCELLWSDNVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAM
                     LHVENSVEIENITLVDNTIGLLAVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQ
                     DKVKPHSANLTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMK
                     LQDVTFSSFVKSCYSDDLDVCILPNAENSGIMHPITAERTRMLKIKDKNKFYFPSLQP
                     RKDLGKVVCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTEAEWTASFFNAGTFRE
                     EQKCTYQFLMQGFICKQTDQVVLILDSADAIWAIQKLYPVVSVTSGFVDVFSSVNANI
                     PCSTSGSVSTFYSILPIRQITKVCFMDQTPQVLRFFLLGNKSTSKLLLAVFYHELQSP
                     HVFLGESFIPPTLVQSASLLLNESIGANYFNIMDNLLYVVLQGEEPIEIRSGVSIHLA
                     LTVMVSVLEKGWEIVILERLTNFLQIGQNQIRFIHEMPGHEETLKAIADSRAKRKRNC
                     PTVTCTSHYRRVGQRRPLMMEMNSHRASPPMTVETISKVIVIEIGDSPTVRSTGMISS
                     LSSNKLQNLAHRVITAQQTGVLENVLNMTIGALLVTQSKGVIGYGNTSSFKTGNLIYI
                     RPYALSILVQPSDGEVGNELPVQPQLVFLDEQNRRVESLGPPSEPWTISASLEGASDS
                     VLKGCTQAETQDGYVSFYNLAVLISGSNWHFIFTVTSPPGVNFTARSKPFAVLPVTRK
                     EKSTIILAASLSSVASWLALSCLVCCWLKRSKSRKTKPEEIPESQTNNQNIHIHISSK
                     RRESQGPKKEDTVVGEDMRMKVMLGKVNQCPHQLMNGVSRRKVSRHIVREEEAAVPAP
                     GTTGITSHGHICAPGAPAQQVYLQETGNWKEGQEQLLRYQLAGQNQLLLLCPDFRQER
                     QQLPGQSRLSKQSGSLGLSQEKKASCGATEAFCLHSVHPETIQEQL"
ORIGIN      
        1 gacacaaacg agttaggtga gttatagtct aacgtgagtg agttacctgc gtggtggctg
       61 caggctgagc tctaaccaga taacatgtcc acggattctt gacagagaga aataagatca
      121 cttagaaaga aaggatcatt tctcccttga gtcacaagga gacagaaaca gaaaaaaaag
      181 cacaaaagct atgctgctcc aatcaaaact gaaaatgctt ttaatgtctg agcaatctta
      241 agagtattga tttaagtgga cagaatgact gcctggctga tctctctgat gagtattgaa
      301 gtactacttt tggcagtacg tcacctgagt ttacatattg aacctgaaga aggtagcctt
      361 gcagggggaa cgtggatcac agtcattttt gatggtttgg agttgggtgt tctttacccc
      421 aacaatggct ctcaattgga gatacacctg gtgaacgtga acatggtggt gcccgcactg
      481 cggagtgttc cctgtgacgt ctttcctgtt ttcttggatt tgcctgtggt gacatgccgg
      541 accagatctg tgctgtctga agcacatgag ggtctgtact tcctggaagc atacttcggg
      601 ggacagctgg taagcagtcc aaatccagga ccacgagata gctgtacttt caagttttcc
      661 aaggcgcaga cacccatcgt tcaccaagtt tatccaccaa gtggtgttcc aggaaaacta
      721 atacatgtat atggctggat tatcactgga agattggaaa cttttgattt tgatgctgag
      781 tacattgata gcccagtgat cttggaagct caaggagaca aatgggttac tccttgctct
      841 cttataaata ggcagatggg aagctgttat cctattcagg aggaccatgg tcttgggact
      901 ctgcagtgcc atgtggaagg cgactacatc ggctcccaga atgttagctt ctcagtattt
      961 aacaaaggaa agtcaatggt ccacaagaag gcatggctga tcagtgctaa acaggatctt
     1021 ttcctatacc agacacactc agaaatatta tctgtgtttc cagaaactgg gagccttggg
     1081 ggaagaacaa acatcacaat tacaggagac ttttttgaca attctgccca ggttaccatt
     1141 gcaggcattc catgtgatat tagacacgtg tctcccagga agattgagtg caccactcgg
     1201 gctccaggaa aagatgtgag gctcaccacc cctcagccag gcaatcgagg gcttcttttt
     1261 gaagttggag atgctgttga gggactggaa ctgactgaag ccaccccagg gtacaggtgg
     1321 cagattgtcc ctaatgccag ttctccattt gggttttggt cacaggaagg acaacctttc
     1381 agagcacggc tcagtgggtt ctttgtggct ccagagacaa ataattacac tttctggatt
     1441 caggcagata gccaagcttc cttgcatttc agttggtcag aggaaccaag gactaaggtg
     1501 aaagtggcct ccatcagcgt cggcactgct gactggtttg actcctggga gcagaatagg
     1561 gatgaaggga cctggcagca gaagactccc aagttggagc tgttgggtgg agccatgtac
     1621 tacctggaag cagagcatca tgggatagcc ccaagcaggg ggatgaggat tggtgtccag
     1681 attcacaaca cctggctgaa tcctgatgtg gtcaccactt acctacggga gaagcaccag
     1741 atccgagtcc gagcccagag gcttccagaa gtacaggtgc tgaatgtatc aggcagagga
     1801 aacttcttcc ttacttggga caatgtctct agtcagccaa tccctgcaaa tgccacagcc
     1861 catctgattc aaacaaccat tgaggagtta cttgcagtaa aatgcaaact ggaacccctt
     1921 tggtctaaca tccttctccg gcttggattt gaacgaggcc cagaagtttc caactctgat
     1981 ggggacctca ccagtgggac ggagcccttc tgtggcaggt tcagcctccg tcagcctcga
     2041 caccttgtcc ttactccccc ggctgcccag aagggctatc ggctagatca gtatacacac
     2101 ctgtgtcttg catacaaagg ccacatgaac aagatcctga agatgattgt gtccttcaca
     2161 atcggctttc aaaacatggt aaagaatacc acctgtgact ggagtctcac gaggaccagc
     2221 cccgagagct ggcagttcga ttgcactgac ctctgggaga cttgtgtgcg ttgcttcggg
     2281 gatctccagc cccctccggc aaactcccca gtgctggttc atcagatcaa ccttctccct
     2341 ctggcccagg agacgggcct gttctatgtg gatgaaatta ttattgcaga cacaaacgta
     2401 acagtttctc aagctgattc tggaacggct cgcccagggg gcaatctggt ggaatcagtc
     2461 tctgtggtgg gatcccctcc ggtctacagt gtcacctcct ggctggcggg gtgtggcacg
     2521 gagctcccgc tcatcactgc acgctctgtg cccactgaag gaacagaaga gggatctgga
     2581 ctggtcctgg tgacgacaca gagacgacag cggacaagtc cacctctagg aggacacttt
     2641 cgcatccagc ttcctaatac agtgatttct gatgtccctg tacaaatttc tgctcatcac
     2701 cttcaccagc tcttacagaa taatgccgat gacttcacat ccaggtacct caatgccagt
     2761 gacttcactg tgaaggagga tctatacact tgctacgaac acgtgtggac cttgtcctgg
     2821 tccactcaga ttggggattt gcccaatttt atcagggtct ctgatgaaaa ccttactgga
     2881 gtgaatcctg ctgcagccac gcgtgtggta tatgatggtg gagtttttct tggacccata
     2941 tttggagaca tgttggctac tgccaaccag catactcagg tggttgtgcg agtgaatgat
     3001 gtaccagctc attgcccagg ttcctgctct ttccagtacc tccaagggtc aactccctgt
     3061 gtccattctg tgtggtactc cattgatggt gacatcaacc taatgattta cattaccgga
     3121 actggtttct ctggtgactc ccagttcttg caggttacag tgaacaaaac gagttgcaaa
     3181 gttattttct caaaccagac caatgtagtc tgtcagacag atttgctacc tgttggaatg
     3241 catcggatct tgatgttggt gagaccctct ggtcttgcca tcagtgccac tggagaagac
     3301 ctcttcctaa atgtgaaacc tagactggat atggtggagc cttccagagc tgcggatatt
     3361 ggagggctct gggccaccat ccgaggctct agtttggaag gtgttagcct gatattattt
     3421 ggatcttact cgtgtgccat caatgtcgct acaagcaatt caagcagaat tcagtgcaaa
     3481 gttccaccca gggggaaaga tggacgcatt gtgaatgtga ctgtgatcag aggggactat
     3541 tctgcagttc ttcccagagc atttacatat gtctcttcct taaatccagt tattgtgact
     3601 ctgagcagaa acataagcaa tatagcaggc ggtgagaccc tggtcattgg agtggcgagg
     3661 ctgatgaact atacggattt ggatgtggaa gtccacgtcc aggatgcctt ggctccggtt
     3721 cacacacagt cggcttgggg cctggaggtg gcactgcccc cactgccagc tggtctccac
     3781 agaatttccg tctctatcaa tggggtcagc attcactcac aaggggttga tctccacatc
     3841 cagtacctca cagaagtttt cagcatcgag ccttgctgtg ggtccctgct gggagggacc
     3901 atcctcagca tctcaggaat aggcttcagc agggacccag ctttggtttg ggtacttgtg
     3961 ggcaatcggt cctgtgacat tgtgaactta acggaggcga gcatctggtg tgaaaccctg
     4021 ccagcccccc agatacccga tgcgggcgct cccactgttc cagctgccgt ggaggtctgg
     4081 gctggcaaca ggttcttcgc ccgtggtcct tcaccaagct tggtggggaa aggcttcacc
     4141 ttcatgtatg aagcggcagc aacaccagta gtcactgcca tgcaaggaga aatcacaaat
     4201 agcagcctga gcctgcatgt gggaggaagt aacctctcca actcagtcat ccttctgggg
     4261 aacctgaact gtgatgttga gacacagtcc ttccagggca acgtgagcct gtctggatgc
     4321 tccatccctc ttcacagtct ggaggctggc atctatcctc tccaaaattt cagcttacat
     4381 ggtggaagcc tcttgaccat agagggcaca ggcctgagag gacagaacac cacgtcagtc
     4441 tatattgacc agcagacctg cctgacggtg aacatcggtg ctgagctcat ccggtgcatt
     4501 gttcccacag ggaatggctc tgttgccctg gaaatagagg tagatggact ttggtatcac
     4561 ataggagtca ttggttataa caaggccttt accccagaat tgatctctat ttctcagagc
     4621 gatgacatct taacctttgc agtggcccag atctcaggag ctgcaaacat tgacattttt
     4681 ataggaatgt caccctgtgt gggtgtctct ggtaaccaca ccgttcttca gtgcgtggtc
     4741 ccttcccttc cggccgggga gtaccacgtc agaggctatg actgcatcag agggtgggcc
     4801 tcatctgccc tggtgttcac ctcaagagtt attattacag cagtgacgga gaacttcggc
     4861 tgcctgggtg gaaggctggt gcatgtgttt ggagcgggat tttctccagg gaatgtctca
     4921 gctgctgtgt gtggtgctcc ctgccgagtc ctggctaatg ctacagtgtc tgccttcagc
     4981 tgcttggttc tgcccctgga tgtgtccttg gccttcctgt gtggcctgaa gcgtgaggag
     5041 gacagctgtg aggctgccag acacacctat gtgcagtgtg atttgacagt tgccatggcg
     5101 acagagcaac tgcttgaatc gtggccttac ctctacattt gcgaggaaag ttcccaatgc
     5161 ctctttgtgc cagatcattg ggcagagtca atgtttccat cattctcggg cctctttatc
     5221 agccctaaat tggaaagaga tgaagttctc atctataata gctcctgtaa cattaccatg
     5281 gaaactgagg cagagatgga gtgtgagacg cccaatcagc caattaccgt caagattact
     5341 gagatacgga aacgctgggg ccagaacact cagggcaact tttctttaca gttctgccgg
     5401 agatggtcca ggactcacag ctggtttcct gaaaggctgc cacaagatgg cgacaacgtc
     5461 acagtggaga atggccaatt gcttctgctg gacactaaca caagcatcct caacttactg
     5521 cacattaaag ggggcaagct gattttcatg gccccaggac ccatcgagct cagggcacac
     5581 gccatccttg tttctgatgg tggagagctc cggattggat ccgaagacaa gcccttccaa
     5641 ggcagagctc agatcacact ctacgggagt tcctactcaa ctcccttctt tccctatgga
     5701 gtcaagttcc tggctgtgag gaatggaact ctttctctgc acggttcact accagaagta
     5761 attgtcacct gtcttagagc aactgcccat gccctagaca cagtgctggc tttagaagat
     5821 gctgtggact ggaaccctgg ggatgaagtt gtcatcatca gtggaacagg tgttaaaggt
     5881 gccaaaccga tggaagagat tgtcactgtg gaaactgtgc aggatacaga cctctatctt
     5941 aagtcacctt tgagatattc tcacaacttt acagagaatt gggtggctgg agagcaccat
     6001 attttaaagg ccactgtggc tctgctcagc aggagtatta ccatacaagg aaatctcact
     6061 aatgagaggg agaagctgct tgtttcatgc caggaggcca atgctccaga aggtaatctg
     6121 cagcactgtt tgtattccat gagtgagaag atgctaggat ccagggatat gggagccaga
     6181 gtgatcgttc agtccttccc agaagagccc agccaggtcc agttgaaggg agtgcagttt
     6241 caagtcttgg ggcaagcctt ccataagcat ctgagctcac tcactctggt gggagctatg
     6301 agagagtctt tcatacaggg ctgcacagtg aggaactcct tcagtagagg cctcagcatg
     6361 tgcgggacct tgggcctgaa ggtggacagt aatgtattct acaatatttt aggtcatgcg
     6421 ctgctagttg ggacatgcac ggagatgaga tatatctcct gggaggcaat tcatggaagg
     6481 aaagatgact ggtcaggaca tggaaatata ataagaaaca acgtgatcat ccaggtttct
     6541 ggtgccgagg gactctccaa tcctgaaatg ttgacaccat ctggcatcta tatctgcagt
     6601 cccaccaatg ttatagaggg gaacagagtg tgtggtgctg gctatggcta ctttttccat
     6661 ctcatgacca accaaacatc acaagctccg cttctttcct tcactcagaa cattgcacat
     6721 tcttgtacca ggtatggtct ctttgtatac cctaaatttc agccaccttg ggataatgtc
     6781 actggcacca ctctgttcca gagcttcaca gtttgggaaa gtgcaggtgg tgcccagatt
     6841 tttagaagta gcaatcttcg cctgaaaaac ttcaaagttt attcatgcag agattttgga
     6901 attgacgtct tggaaagtga tgcaaatact tcagttactg acagcttatt acttggtcat
     6961 tttgcccaca agggaagtct gtgtatgtca tctgggatta aaactcctaa aagatgggaa
     7021 ctgatggtgt ctaacacaac ctttgttaat tttgatctca tcaactgtgt ggccattaga
     7081 acctgttcag actgttccca aggacaaggt ggatttactg tgaagaccag ccagttgaag
     7141 tttacaaact cttcaaactt agtggcattt ccatttcctc atgcagcaat tttggaagac
     7201 ttggatgggt ctctgtctgg gaaaaacaga agtcacattc ttgcttctat ggaaaccctt
     7261 tcagcttctt gtttggtcaa ttcaagcttt ggtcgggttg tccatggcag tgcctgtgga
     7321 ggaggtgttc tttttcatcg tatgtctatt ggtttagcga atactcctga agtttcttat
     7381 gatttaacca tgactgacag cagaaataaa acaaccactg tcaattatgt acgtgataca
     7441 ttgtctaacc ctcgtggctg gatggctctg ctcttggacc aagagaccta ctcattgcaa
     7501 tctgagaacc tttggatcaa cagatctctg cagtactcag caacctttga caactttgct
     7561 cctggtaatt acctactgct ggtgcacaca gatttgccgc cttaccctga catcctccta
     7621 agatgtggga gtcgagtggg tctgtctttt ccatttcttc catcaccagg tcagaaccaa
     7681 ggctgtgact ggttcttcaa tagccagctg aggcaactca cctatctggt ttcaggtgaa
     7741 ggccaagttc aagtcattct ccgggtgaag gaaggtatgc ccccaactat ttcagcttct
     7801 acctctgccc ctgaatcagc tttaaaatgg tccctccctg aaacatggca aggtgttgaa
     7861 gaaggctggg gaggatacaa caataccatt ccaggccctg gggatgacgt tctcatttta
     7921 cccaacagaa ctgtccttgt ggatacagat cttccattct tcaaagggct gtatgtgatg
     7981 gggaccttag acttccctgt ggacagaagc aatgttctga gtgtggcatg catggtcatt
     8041 gcaggcgggg agctgaaagt tggtacttta gaaaatccct tagaaaagga acaaaagctt
     8101 ctgattctcc ttagagcctc agagggagtc ttttgtgacc gtatgaatgg aattcatatt
     8161 gacccaggaa caattggggt ttatgggaaa gttcatcttt acagtgctta tcctaagaac
     8221 tcctggacac atcttggagc tgatattgcc tcaggaaatg agagaattat agtagaagat
     8281 gcagtggatt ggcgccccca tgacaaaata gtccttagct cctcttctta tgagcctcat
     8341 gaagcagagg tcctcactgt gaaagaagtc aagggccacc atgtgaggat ctatgaacgg
     8401 ctcaaacacc ggcatattgg aagtgtacat gtcacggagg atggccgaca cattcgtttg
     8461 gctgctgagg ttggactgtt gacccgaaat atacaaattc agcctgacgt atcatgtagg
     8521 gggagactgt ttgtggggtc cttcaggaag tccagccgag aagaattttc aggtgtcctt
     8581 caacttctta atgtggaaat tcagaacttc gggtcaccat tgtactcatc tgttgaattc
     8641 agtaatgtgt cagcaggatc ctggatcata tcatctactc tgcaccagag ctgtggcggg
     8701 ggcattcatg cagctgccag tcatggagta cttttaaatg acaatattgt gtttggcaca
     8761 gctggccatg gcatagattt agagggtcag gcctatactg tcactaataa ccttgtggtt
     8821 ctgatgacac agccagcgtg gtccaccatt tgggtggcgg gaatcaaagt gaaccaggta
     8881 aaggacatca acctccatgg caacgttgtg gcaggatcag agagacttgg ctttcacatc
     8941 cgaggccaca agtgctcctc ttgtgaactg ctttggtctg acaatgtggc gcattcaagt
     9001 cttcatggcc ttcatctcta taaggaaagt ggacttgaca actgtaccag aatctctggc
     9061 ttcttggctt tcaagaactt tgactatggt gccatgttac atgtagagaa cagcgtggag
     9121 atagagaaca ttactctggt agacaatact attggtcttt tggcagtagt gtatgtattt
     9181 tctgctccac aaaattccgt caaaaaagtg cagattgtgc ttaggaattc agtcattgtg
     9241 gccaccagct cttcttttga ctgcattcag gacaaagtga agccgcactc agccaacttg
     9301 acatcaacag atagagctcc ctccaatcca agaggaggtc gaattggtat tctgtggcct
     9361 gtattcacct cagaaccaaa tcagtggcct caggagccat ggcacaaagt gaggaatgat
     9421 cattcaattt caggaatcat gaaacttcaa gatgttacct tttctagttt tgtgaagagt
     9481 tgctatagcg atgacctgga tgtctgcatt ctaccaaatg cagagaacag tggaattatg
     9541 cacccaataa cagcagagag gaccaggatg ctaaagataa aagataaaaa caagttctac
     9601 tttccttcat tacaacccag gaaagattta ggaaaagtag tctgtcctga attagactgt
     9661 gcaagtccaa gaaaatatct cttcaaggat ctggatggga gagccctggg tctgcctcca
     9721 ccagtttctg tatttcctaa aacagaggca gaatggactg catccttctt caacgcaggt
     9781 acatttagag aagaacagaa atgtacatac caatttctga tgcaaggatt catctgcaaa
     9841 cagactgacc aagtggtcct aattcttgat agcgctgatg ccatttgggc aattcagaag
     9901 ttatatccag ttgtatctgt gactagtggt tttgttgatg tctttagcag tgtaaatgcc
     9961 aatattccct gctctacttc tgggtcagtg tctactttct attctatctt acccatcagg
    10021 caaatcacca aagtctgctt catggatcaa actcctcaag ttttgcgctt ttttctattg
    10081 gggaacaaaa gtacctccaa gcttctcttg gctgtattct accatgagct ccagagcccc
    10141 cacgtcttct taggggaaag ttttattcca cccactctgg ttcagtcagc ttccttattg
    10201 ctgaatgaat ctattggtgc caactatttc aacatcatgg ataacctctt gtatgttgtc
    10261 ctacaaggag aggagcccat tgaaatacgc tcaggtgttt ccattcactt ggccctcact
    10321 gtgatggttt cagtcttaga aaaaggctgg gaaatagtaa tactcgaaag actaactaac
    10381 ttcttacaga ttggccaaaa ccaaatcagg tttattcacg agatgcctgg ccatgaagag
    10441 accttaaagg ccattgctga cagtagagca aaaagaaagc gcaattgccc tactgtgact
    10501 tgcactagtc attatagaag agttggtcaa cgtaggcctc tcatgatgga aatgaactca
    10561 catagggctt cacccccaat gactgtggaa actatctcaa aagtgattgt cattgaaatt
    10621 ggtgattcgc caacagtaag gagcactgga atgatttcat ccttatcaag taacaaatta
    10681 cagaatttgg ctcatcgagt catcactgct caacagactg gggtactaga gaatgttctg
    10741 aatatgacta tcggggcctt actagttact cagtcaaagg gagtcattgg ctatggaaat
    10801 acaagcagtt ttaaaactgg gaacttgata tatattcggc cctatgcact ttccatccta
    10861 gtccagcctt cagatggaga agtgggaaat gagcttccag tgcagccaca attggtattt
    10921 ttggatgagc agaatcgaag agtagagtcc ctgggacctc cttcagagcc atggacaatt
    10981 tcagcttccc tggaaggagc atcagactca gtgctaaaag ggtgcaccca ggcagaaact
    11041 caagatggtt atgttagctt ctacaacttg gcagtcttga tctctgggtc aaactggcac
    11101 tttattttta ctgtcacttc tcctccagga gtcaatttta cagctcgatc caagccattt
    11161 gctgtcttgc ctgtgactag gaaggagaag tcgaccatca tcctggctgc ttccctgtcc
    11221 tctgtggcct catggctggc tctgagctgt ctggtgtgct gttggcttaa aagaagcaaa
    11281 agcagaaaaa caaaacctga agagattcct gaatcccaga ctaataatca aaatattcat
    11341 atccacatct catccaaacg ccgagaatca caagggccca aaaaagaaga cactgtggtg
    11401 ggagaagata tgagaatgaa ggtcatgctg ggcaaggtga accagtgccc ccaccagttg
    11461 atgaatggag tgtccagaag gaaagttagc cgccacattg tccgagagga agaggctgct
    11521 gtgcctgctc ctggtactac tggcatcaca tcccatgggc acatctgtgc tccaggtgct
    11581 cctgctcagc aggtgtacct gcaagagact gggaactgga aggagggcca agagcagttg
    11641 ctcagatacc agctggcagg ccaaaatcag ctgctgctgc tatgcccaga cttcagacaa
    11701 gagaggcagc agttgccagg gcaaagtcgg ctgagtaagc aaagtggcag cttggggctt
    11761 tcccaagaga agaaagcctc ctgcggggcc actgaggcat tctgccttca ttcagtacac
    11821 ccggaaacta ttcaggagca actgtgatca gggaagttgg gggcatttgg cctgaaaggc
    11881 agaatgttcc cagtatttct ggataataag ctggggaagt gaggactgtc ctgctgggac
    11941 aactaagaag agagaatgtg gactctgaat ccctttttca actttaaaat ggaaaacagt
    12001 catataaatg cttacagact gaaaaatgtc tcatacatat tttgcagcta tcatgatcct
    12061 agttcaatgc taggcaaata atggcacttg ttaattattt accagttttt aacttaagcc
    12121 tgattttaac aacttgataa tggtgtaata ctgacttata ccagcagggg ttattattaa
    12181 gcattctctg gattgaccac ccacaatgct ttgagcttct tttatagaag ggatcatgaa
    12241 aaggtctggt cagctacagt ttaattccac actgttacag aaaagcattt ctttatcctg
    12301 tagtagcatt tgaagggaca gttcaacacc ctgctccctg atctgtcaga gcttaccttc
    12361 caaccacaag gcaacttcct ggctttttac aagtggattt tatttcatgg tttaaattca
    12421 atcattattg agaacctaca gtagtgtgag cgtatcaaat ttgcacttca tgaggattta
    12481 cacatgaaaa ttgatattct catgggcttt gctgagagtt tagttaagga caaagatgta
    12541 aaaatgccaa atttgggaaa ggaaattttg tatgaccact gttctatttt tcagtgattc
    12601 tctctgttag tagctgggtc acatttacaa ctggaaaaga actacattgg gagatcagag
    12661 aaagccaagt ggccaagtcc tttatcaaaa agctgctttt tggagaagat gatgcataaa
    12721 gctgtgatac taaggagagg agagattatg tcatatgcaa ctgctctagg ctgtgcaggg
    12781 ggtttaaatg gagatcagaa caaaggctca cctggtattg atacatttgg taaggttgtt
    12841 aaaggcaatt tcaccaaatt cacacatttg tacggggccc atttcttttc aaactgaaga
    12901 atactttaaa cagcctgact gtgtccttgg ctctggatcc agaaggcctt atgctccaag
    12961 catgtaaaga aaagatcgca ggaatgtgga gagcttccaa aaagagattg ctctcagatt
    13021 ttcctgaaaa tcctgaaaac caggattttc caatctctac aatgttaagg ggttgttgtg
    13081 tagttgcatt ggaagagaga aaggaaacac actctttcat tgctgaattc taaataatga
    13141 tgccctgaat tagttctatg agaagtactg gcagacagct gttatgtctg cagggcatca
    13201 aggggcaggt gtgtctcacc ctactaagaa ttggcagaaa tgttttaacc tcttctttag
    13261 gcatctggtg agtattgcag atcttcaggc tgtccctaaa aggaggtagg tagccttctc
    13321 tgtggtcact gtgttggatt tggaagaaaa tataagtaga tgttaaggtc agtgctctcc
    13381 aggagatttc aatccaggct atctgtgttc agggaatgat ttgcaagaag ttggtttata
    13441 gacgtttact ctggaggcac aagctggctg ccatgctgag taagtcctct ttgtagatga
    13501 tgtattttgc ttgggcacca acagaattaa aaacgaaaaa caaaaaaaaa ctcgaatgac
    13561 ttaggcagaa catgccttcc ctagtttaat tagtccctgt tataaccagt tatttatctt
    13621 tttttgtaga ttctcggtct tgaagtcatt tgcctttgca atctctactt tagtatactc
    13681 attggatcct caaagagccg taagcttttt ggaaaaaaac atttcagaag tgaaggcttt
    13741 tgaggtttat aaaatggtag cagtcttagt ccttgccctg cctcagttta cctgcacatg
    13801 ctttctttca tttcctcgga ttctttcacc actttttaag ttttttttcc acaggtattt
    13861 ttcctgagct ctataccatg catttagctg cctagtgaga atatccagta ggttatccta
    13921 tagttactat gaagttaaca cagcccaaaa acctacttct ccttgtgttt ttttccaact
    13981 caatgaatga catcactgca ctcagaccag aaatctagaa gtcagtcatg actcttcatt
    14041 ctatttcgcc cttcacaaag agttagctgc cagctctgtt atttctgccc cttctttacc
    14101 cttcttccaa tttttattat cttcttattt atcctctatg tgtcacaaga ccagtctttc
    14161 tgggaggcat gttttatcct atccctctgc gtaggaataa ccataattat cttactaatt
    14221 ccatcccaga aaagcctgtg atccctgagg ccagaattga ctctttgggc ctaaatagca
    14281 gctataaaca tcttcagtaa cttgccaggc tctagcatgt ggcatggaat tttggcatct
    14341 agctaaaatt cctcaaccca tagttaagct actcctcttt ctcctaaaaa aaaaaaaaaa
    14401 tgagagaatt agggaaacac caaaagcaaa gagagcagct ctatgttcat tcatgtctgg
    14461 agatgagcca atttgagcac cactgtaggc caactctaaa tttattcaga tcgttaacat
    14521 gggtaaccca gcaaatattt cccagcagtg acaatctaca ccctttatct aaataaatat
    14581 tgagatgtgc ttttttcctg tgttagttca aagaatctct tcttgcctcc cattgctgat
    14641 tttctgtatt gatggactca tttctctcaa gagattggac aagctaaaat tctagagagt
    14701 tcaaaagtgt ttgaaagtac attttaagtg ttctcaccac aaaaaatgct agtgtgtgag
    14761 gtgatacata tgttaattag ttcaactgat ccattccaca atgtatacat atttcaaact
    14821 atcgagttgt acatgataaa tatatacaat ttttatttgt caaataaaga acatctataa
    14881 atatttatag atttcaaaat tgagaaagaa gtatatatgg agccacggtt gttttgacca
    14941 tttctccatg ctttttgttt ggggaggggg acattttttg gggggcaggg actgtgttca
    15001 gggaaagtac ctgaccaaca gaacttcaag tctcttccag agtgcgagac tcagcttatc
    15061 tgatcaaggt gaacttgccc ttcaatagac ttgcccttgt tactgcccag tgaggccacc
    15121 aaggaccaag aacagttgag ctctctcagg gccttcccct ttcaacaatt tagttgaatg
    15181 actcccttcc atctatcagt cttactccaa atatatgaaa ttactataca ttgaaatgcc
    15241 tgcaaactat atgcaaaaat gagtatgagg aaatcaaatg taaatcatat gcaaatatta
    15301 ttcaaccaag cttctataaa attgtacgtg tcaataacag taaagaattt taattaattc
    15361 tgtcatttaa aattcatgca ttccatattt tgctttcaga acttatagtc tatgccaatt
    15421 ttgaaaaaac tataagcaca aggaattaaa tactattgag tatagaactg ttgatttcaa
    15481 catacactat agcactttga ctaattacag atatatttga tagaaaagtc acatttctac
    15541 aaggtaattt tcaaaaagaa ataaaacatt tctgtaaact taaatgtgga ttaagtggca
    15601 gaatacagag atttgaatgt ttacaaata
//
