LOCUS       XM_011532030            4409 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens polycystin 2, transient receptor potential
            cation channel (PKD2), transcript variant X3, mRNA.
ACCESSION   XM_011532030
VERSION     XM_011532030.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011532030.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4409
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..4409
                     /gene="PKD2"
                     /gene_synonym="APKD2; Pc-2; PC2; PKD4; TRPP2"
                     /note="polycystin 2, transient receptor potential cation
                     channel; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 31 ESTs, 888 long SRA
                     reads, 5 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 98 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:5311"
                     /db_xref="HGNC:HGNC:9009"
                     /db_xref="MIM:173910"
     CDS             260..2326
                     /gene="PKD2"
                     /gene_synonym="APKD2; Pc-2; PC2; PKD4; TRPP2"
                     /codon_start=1
                     /product="polycystin-2 isoform X3"
                     /protein_id="XP_011530332.1"
                     /db_xref="GeneID:5311"
                     /db_xref="HGNC:HGNC:9009"
                     /db_xref="MIM:173910"
                     /translation="MFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQL
                     RVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGI
                     IATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVR
                     LLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIH
                     KLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLAYWQI
                     QFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQL
                     AYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFIL
                     LNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLR
                     QGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKERED
                     LDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRV
                     DRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQ
                     MERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNG
                     SSNVHV"
ORIGIN      
        1 gtgacctacg gcatgatgag ctccaatgtg tactactaca cccggatgat gtcacagctc
       61 ttcctagaca cccccgtgtc caaaacggag aaaactaact ttaaaactct gtcttccatg
      121 gaagacttct ggaaggtatt tgcaaataac tttgaaagta cctctctatc acagaaaatt
      181 gttcatttgg cttcatcatt tcaatgcatg agtatcgaca ggacctgctt tgcatttaac
      241 actgtgtgag acgtaagtta tgttcacaga aggctcctta ttggatgggc tgtactggaa
      301 gatgcagccc agcaaccaga ctgaagctga caaccgaagt ttcatcttct atgagaacct
      361 gctgttaggg gttccacgaa tacggcaact ccgagtcaga aatggatcct gctctatccc
      421 ccaggacttg agagatgaaa ttaaagagtg ctatgatgtc tactctgtca gtagtgaaga
      481 tagggctccc tttgggcccc gaaatggaac cgcttggatc tacacaagtg aaaaagactt
      541 gaatggtagt agccactggg gaatcattgc aacttatagt ggagctggct attatctgga
      601 tttgtcaaga acaagagagg aaacagctgc acaagttgct agcctcaaga aaaatgtctg
      661 gctggaccga ggaaccaggg caacttttat tgacttctca gtgtacaacg ccaacattaa
      721 cctgttctgt gtggtcaggt tattggttga attcccagca acaggtggtg tgattccatc
      781 ttggcaattt cagcctttaa agctgatccg atatgtcaca acttttgatt tcttcctggc
      841 agcctgtgag attatctttt gtttctttat cttttactat gtggtggaag agatattgga
      901 aattcgcatt cacaaactac actatttcag gagtttctgg aattgtctgg atgttgtgat
      961 cgttgtgctg tcagtggtag ctataggaat taacatatac agaacatcaa atgtggaggt
     1021 gctactacag tttctggaag atcaaaatac tttccccaac tttgagcatc tggcatattg
     1081 gcagatacag ttcaacaata tagctgctgt cacagtattt tttgtctgga ttaagctctt
     1141 caaattcatc aattttaaca ggaccatgag ccagctctcg acaaccatgt ctcgatgtgc
     1201 caaagacctg tttggctttg ctattatgtt cttcattatt ttcctagcgt atgctcagtt
     1261 ggcatacctt gtctttggca ctcaggtcga tgacttcagt actttccaag agtgtatctt
     1321 cactcaattc cgtatcattt tgggcgatat caactttgca gagattgagg aagctaatcg
     1381 agttttggga ccaatttatt tcactacatt tgtgttcttt atgttcttca ttcttttgaa
     1441 tatgtttttg gctatcatca atgatactta ctctgaagtg aaatctgact tggcacagca
     1501 gaaagctgaa atggaactct cagatcttat cagaaagggc taccataaag ctttggtcaa
     1561 actaaaactg aaaaaaaata ccgtggatga catttcagag agtctgcggc aaggaggagg
     1621 caagttaaac tttgacgaac ttcgacaaga tctcaaaggg aagggccata ctgatgcaga
     1681 gattgaggca atattcacaa agtacgacca agatggagac caagaactga ccgaacatga
     1741 acatcagcag atgagagacg acttggagaa agagagggag gacctggatt tggatcacag
     1801 ttctttacca cgtcccatga gcagccgaag tttccctcga agcctggatg actctgagga
     1861 ggatgacgat gaagatagcg gacatagctc cagaaggagg ggaagcattt ctagtggcgt
     1921 ttcttacgaa gagtttcaag tcctggtgag acgagtggac cggatggagc attccatcgg
     1981 cagcatagtg tccaagattg acgccgtgat cgtgaagcta gagattatgg agcgagccaa
     2041 actgaagagg agggaggtgc tgggaaggct gttggatggg gtggccgagg atgaaaggct
     2101 gggtcgtgac agtgaaatcc atagggaaca gatggaacgg ctagtacgtg aagagttgga
     2161 acgctgggaa tccgatgatg cagcttccca gatcagtcat ggtttaggca cgccagtggg
     2221 actaaatggt caacctcgcc ccagaagctc ccgcccatct tcctcccaat ctacagaagg
     2281 catggaaggt gcaggtggaa atgggagttc taatgtccac gtatgatatg tgtgtttcag
     2341 tatgtgtgtt tctaataagt gaggaagtgg ctgtcctgaa ttgctgtaac aagcacacta
     2401 tttatatgcc ctgaccacca taggatgcta gtctttgtga ccgattgcta atcttctgca
     2461 ctttaattta ttttatataa actttaccca tggttcaaag attttttttt ctttttctca
     2521 tataagaaat ctaggtgtaa atattgagta cagaaaaaaa atcttcatga tgtgtattga
     2581 gcggtacgcc cagttgccac catgactgag tcttctcagt tgacaatgaa gtagcctttt
     2641 aaagctagaa aactgtcaaa gggcttctga gtttcatttc cagtcacaaa aatcagtatt
     2701 gttatttttt tccaagagtg tgaaggaaaa tggggcattc ctttccactc tggcatagtt
     2761 catgagctta atacatagct ttcttttaag aaaggagcct tttttttcaa ctagcttcct
     2821 ggggtaaact tttctaaaag ataaaatgga aaggaactcc aaactatgat agaatctgtg
     2881 tgaatggtta agatgaatgt taaatactat gcttttttgt aagttgatcg tatctgatgt
     2941 ctgtgggact aactgtatca cttaattttt accttatttt ggctctaatt tgaataagct
     3001 gagtaaaacc accaaagatc agttatagga taaaatggca tctctaacca taacacagga
     3061 gaattggaag gagccctaag ttgtcactca gtttaatttc ttttaatggt tagtttagcc
     3121 taaagattta tctgcatatt ctttttccca tgtggctcta ctcatttgca actgaattta
     3181 atgttataac tcatctagtg agaccaactt actaaatttt tagtatgcac tgaaagtttt
     3241 tatccaacaa ttatgttcat tttaagcaaa attttaagaa agttttgaaa ttcataaagc
     3301 atttggtttt aaactatttt aagaatatag tactcggtca ggtatgacgg ctcacgcctg
     3361 taatcccagc actttgggag gccgaaacag gcgaatcact tgagcccagg agttcaagac
     3421 caacatgggc aatgtggcga aactccatct ctacaaaaaa tgcaaaaata aaaaatatag
     3481 tactcaagta ttcttgatcc tgtgtttcaa aactagaatt tgtaatgcaa atggagctca
     3541 gtctaataaa aaagaggttt tggtattaaa agttcataca ttagacagta tcagccaaaa
     3601 tttgagttag caacactgtt ttctttacga gagggtctca cccaaattta tggggagaaa
     3661 tctatttctc aaaaaaaaaa atcttctttt acagaaatgt tgagtaaggt gacattttga
     3721 gcgctaataa gcaaaagagc atgcagtgct gttgaataac cctcacttgg agaaccaaga
     3781 gaatcctgtc gtttaatgct atattttaat ttcacaagtt gttcatttaa ctggtagaat
     3841 gtcagtccaa tctccaatga gaacatgagc aaatagacct ttccaggttg aaagtgaaac
     3901 atactgggtt tctgtaagtt tttcctcatg gcttcatctc tatctttact ttctcttgaa
     3961 tatgctacac aaagttcttt attactacat actaaagttt gcattccagg gatattgact
     4021 gtacatattt atgtatatgt accatgttgt tacatgtaaa caaacttcaa tttgaagtgc
     4081 agctattatg tggtatccat gtgtatcgac catgtgccat atatcaatta tggtcactag
     4141 aaagtctctt tatgatactt tttattgtac tgtttttcat ttcacttgca aaattttgca
     4201 gaattcctcc tttctaccca taaattacat atatttttct tctttagtca tggagaactc
     4261 cccccctcat ctcttcccta ttatctttcc ctgtgtactg gtattattaa aaagacatta
     4321 catacgcaag tctttctcga caatcaagaa tgttattaat gtgtaatact gagcacttta
     4381 cttcttaata aaaacttgat atagtagca
//
