LOCUS       XM_011522529           14171 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens polycystin 1, transient receptor potential
            channel interacting (PKD1), transcript variant X4, mRNA.
ACCESSION   XM_011522529
VERSION     XM_011522529.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011522529.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14171
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..14171
                     /gene="PKD1"
                     /gene_synonym="PBP; Pc-1; PC1; TRPP1"
                     /note="polycystin 1, transient receptor potential channel
                     interacting; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 83 ESTs, 1170 long SRA
                     reads, 6 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 1 sample
                     with support for all annotated introns"
                     /db_xref="GeneID:5310"
                     /db_xref="HGNC:HGNC:9008"
                     /db_xref="MIM:601313"
     CDS             190..13152
                     /gene="PKD1"
                     /gene_synonym="PBP; Pc-1; PC1; TRPP1"
                     /codon_start=1
                     /product="polycystin-1 isoform X4"
                     /protein_id="XP_011520831.1"
                     /db_xref="GeneID:5310"
                     /db_xref="HGNC:HGNC:9008"
                     /db_xref="MIM:601313"
                     /translation="MVLTPPAFQIGRSALGTPCVPGLGHRPAPHGGVLLPTSLASASL
                     GAHPGPRAPIRLSLCTWLPPFQLIAGTGNGDGKSRWRREKVREQARDVSHNLLRALDV
                     GLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEE
                     QQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYVACLPDNSSGTVAAVSFSAA
                     HEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSASFACLSLCSGPPPPPAPT
                     CRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPVTATRWDFGDGSAEVDA
                     AGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALELVCPSSVQSDESLD
                     LSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCYRLVVEKAAWLQA
                     QEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGPAPQGEAFSLE
                     SCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQDAENLLVGA
                     PSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELRRPAQLR
                     LQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASCHPQA
                     CANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHDAG
                     PGALLHCSPAPGHPGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV
                     LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYV
                     PTNGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSV
                     VALPWLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYS
                     PVVEAGSDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVT
                     VERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPP
                     YNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPS
                     VAVGVSDGVLVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGT
                     YHVRLEVNNTVSGAAAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWT
                     FDMGDGTVLSGPEATVEHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPA
                     ACIPTQPDARLTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALV
                     LSSRVNRAHYFTSICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGT
                     EEAAPTRARGPEVTFIYRDPGSYLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGS
                     LGLELQQPYLFSAVGRGRPASYLWDLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVS
                     RSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIP
                     GGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFVYVLQLIEGLQVVGGGRYFPTNHTV
                     QLQAVVRDGTNVSYSWTAWRDRGPALAGSGKGFSLTVLEAGTYHVQLRATNMLGSAWA
                     DCTMDFVEPVGWLMVAASPNPAAVNTSVTLSAELAGGSGVVYTWSLEEGLSWETSEPF
                     TTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQVPVSGLSIRASEPGGSFVAAGSSVP
                     FWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAGTFSIRLNASNAVSWVSATYNLT
                     AEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFRLQVGGANPEVLPGPRFSHSF
                     PRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQR
                     GSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSENRTLVLE
                     VQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSY
                     LRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQRNYLEAH
                     VDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPRLALPVGHYCF
                     VFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSESYDPNLED
                     GDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSLTVWKAG
                     RKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGR
                     WAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCAS
                     IRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG
                     HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPN
                     GSATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHER
                     QHRAQIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAM
                     MLILQAETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQA
                     YNLTSALMRILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPE
                     AFSGALANLSDVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLAS
                     ERAITVKVPNNSDWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNY
                     TLLDGHYLSEEPEPYLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGS
                     RDPAGSYHLNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAV
                     CLTRHLTAFGASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQ
                     LDASRGRAIPFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDR
                     AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVN
                     DWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSR
                     FTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVV
                     VYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSFLTFSGLHAEA
                     FVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARGQAGHGLGPE
                     EDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSLSSTPGEK
                     TETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHGLSLLL
                     VAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAKRLH
                     PDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFL
                     LVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGNQ
                     SSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWESPHNGSGTWAY
                     SAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELT
                     RYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVH
                     FAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRP
                     RRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGV
                     TLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLLC
                     VGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGLSK
                     VKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSLGR
                     LGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG
                     PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST"
ORIGIN      
        1 ctgtgacggg tgtggagggg cagcctccag gcctggccac accctctgct gttgctgctc
       61 ctgctccagg attggcaagg gtgctgggaa ggggtgaaga cccgtactgt ggccacacac
      121 ctgggacttc cttctccacc cagtggtgcc ccagcagccg ctaaggagcc cgctgggtcc
      181 cacgctagga tggtcctaac tcctcccgcc ttccagatcg gacgctcggc gctggggacc
      241 ccttgtgtcc cggggctggg gcaccgtcct gccccccatg ggggtgtact cctcccgaca
      301 agcttggctt cagcttccct gggagcacat cctggccctc gggcacccat caggctgtcc
      361 ctgtgcacct ggctcccacc cttccagctc atagcaggaa ctgggaacgg cgatggcaaa
      421 agcagatgga gacgtgaaaa agtacgggag caagcgagag acgtctccca caacctgctc
      481 cgggcgctgg acgttgggct cctggcgaac ctctcggcgc tggcagagct ggatataagc
      541 aacaacaaga tttctacgtt agaagaagga atatttgcta atttatttaa tttaagtgaa
      601 ataaacctga gtgggaaccc gtttgagtgt gactgtggcc tggcgtggct gccgcgatgg
      661 gcggaggagc agcaggtgcg ggtggtgcag cccgaggcag ccacgtgtgc tgggcctggc
      721 tccctggctg gccagcctct gcttggcatc cccttgctgg acagtggctg tggtgaggag
      781 tatgtcgcct gcctccctga caacagctca ggcaccgtgg cagcagtgtc cttttcagct
      841 gcccacgaag gcctgcttca gccagaggcc tgcagcgcct tctgcttctc caccggccag
      901 ggcctcgcag ccctctcgga gcagggctgg tgcctgtgtg gggcggccca gccctccagt
      961 gcctcctttg cctgcctgtc cctctgctcc ggccccccgc cacctcctgc ccccacctgt
     1021 aggggcccca ccctcctcca gcacgtcttc cctgcctccc caggggccac cctggtgggg
     1081 ccccacggac ctctggcctc tggccagcta gcagccttcc acatcgctgc cccgctccct
     1141 gtcactgcca cacgctggga cttcggagac ggctccgccg aggtggatgc cgctgggccg
     1201 gctgcctcgc atcgctatgt gctgcctggg cgctatcacg tgacggccgt gctggccctg
     1261 ggggccggct cagccctgct ggggacagac gtgcaggtgg aagcggcacc tgccgccctg
     1321 gagctcgtgt gcccgtcctc ggtgcagagt gacgagagcc tcgacctcag catccagaac
     1381 cgcggtggtt caggcctgga ggccgcctac agcatcgtgg ccctgggcga ggagccggcc
     1441 cgagcggtgc acccgctctg cccctcggac acggagatct tccctggcaa cgggcactgc
     1501 taccgcctgg tggtggagaa ggcggcctgg ctgcaggcgc aggagcagtg tcaggcctgg
     1561 gccggggccg ccctggcaat ggtggacagt cccgccgtgc agcgcttcct ggtctcccgg
     1621 gtcaccagga gcctagacgt gtggatcggc ttctcgactg tgcagggggt ggaggtgggc
     1681 ccagcgccgc agggcgaggc cttcagcctg gagagctgcc agaactggct gcccggggag
     1741 ccacacccag ccacagccga gcactgcgtc cggctcgggc ccaccgggtg gtgtaacacc
     1801 gacctgtgct cagcgccgca cagctacgtc tgcgagctgc agcccggagg cccagtgcag
     1861 gatgccgaga acctcctcgt gggagcgccc agtggggacc tgcagggacc cctgacgcct
     1921 ctggcacagc aggacggcct ctcagccccg cacgagcccg tggaggtcat ggtattcccg
     1981 ggcctgcgtc tgagccgtga agccttcctc accacggccg aatttgggac ccaggagctc
     2041 cggcggcccg cccagctgcg gctgcaggtg taccggctcc tcagcacagc agggaccccg
     2101 gagaacggca gcgagcctga gagcaggtcc ccggacaaca ggacccagct ggcccccgcg
     2161 tgcatgccag ggggacgctg gtgccctgga gccaacatct gcttgccgct ggacgcctcc
     2221 tgccaccccc aggcctgcgc caatggctgc acgtcagggc cagggctacc cggggccccc
     2281 tatgcgctat ggagagagtt cctcttctcc gttcccgcgg ggccccccgc gcagtactcg
     2341 gtcaccctcc acggccagga tgtcctcatg ctccctggtg acctcgttgg cttgcagcac
     2401 gacgctggcc ctggcgccct cctgcactgc tcgccggctc ccggccaccc tggtccccgg
     2461 gccccgtacc tctccgccaa cgcctcgtca tggctgcccc acttgccagc ccagctggag
     2521 ggcacttggg cctgccctgc ctgtgccctg cggctgcttg cagccacgga acagctcacc
     2581 gtgctgctgg gcttgaggcc caaccctgga ctgcggctgc ctgggcgcta tgaggtccgg
     2641 gcagaggtgg gcaatggcgt gtccaggcac aacctctcct gcagctttga cgtggtctcc
     2701 ccagtggctg ggctgcgggt catctaccct gccccccgcg acggccgcct ctacgtgccc
     2761 accaacggct cagccttggt gctccaggtg gactctggtg ccaacgccac ggccacggct
     2821 cgctggcctg ggggcagtgt cagcgcccgc tttgagaatg tctgccctgc cctggtggcc
     2881 accttcgtgc ccggctgccc ctgggagacc aacgataccc tgttctcagt ggtagcactg
     2941 ccgtggctca gtgaggggga gcacgtggtg gacgtggtgg tggaaaacag cgccagccgg
     3001 gccaacctca gcctgcgggt gacggcggag gagcccatct gtggcctccg cgccacgccc
     3061 agccccgagg cccgtgtact gcagggagtc ctagtgaggt acagccccgt ggtggaggcc
     3121 ggctcggaca tggtcttccg gtggaccatc aacgacaagc agtccctgac cttccagaac
     3181 gtggtcttca atgtcattta tcagagcgcg gcggtcttca agctctcact gacggcctcc
     3241 aaccacgtga gcaacgtcac cgtgaactac aacgtaaccg tggagcggat gaacaggatg
     3301 cagggtctgc aggtctccac agtgccggcc gtgctgtccc ccaatgccac gctagcactg
     3361 acggcgggcg tgctggtgga ctcggccgtg gaggtggcct tcctgtggac ctttggggat
     3421 ggggagcagg ccctccacca gttccagcct ccgtacaacg agtccttccc ggttccagac
     3481 ccctcggtgg cccaggtgct ggtggagcac aatgtcatgc acacctacgc tgccccaggt
     3541 gagtacctcc tgaccgtgct ggcatctaat gccttcgaga acctgacgca gcaggtgcct
     3601 gtgagcgtgc gcgcctccct gccctccgtg gctgtgggtg tgagtgacgg cgtcctggtg
     3661 gccggccggc ccgtcacctt ctacccgcac ccgctgccct cgcctggggg tgttctttac
     3721 acgtgggact tcggggacgg ctcccctgtc ctgacccaga gccagccggc tgccaaccac
     3781 acctatgcct cgaggggcac ctaccacgtg cgcctggagg tcaacaacac ggtgagcggt
     3841 gcggcggccc aggcggatgt gcgcgtcttt gaggagctcc gcggactcag cgtggacatg
     3901 agcctggccg tggagcaggg cgcccccgtg gtggtcagcg ccgcggtgca gacgggcgac
     3961 aacatcacgt ggaccttcga catgggggac ggcaccgtgc tgtcgggccc ggaggcaaca
     4021 gtggagcatg tgtacctgcg ggcacagaac tgcacagtga ccgtgggtgc ggccagcccc
     4081 gccggccacc tggcccggag cctgcacgtg ctggtcttcg tcctggaggt gctgcgcgtt
     4141 gaacccgccg cctgcatccc cacgcagcct gacgcgcggc tcacggccta cgtcaccggg
     4201 aacccggccc actacctctt cgactggacc ttcggggatg gctcctccaa cacgaccgtg
     4261 cgggggtgcc cgacggtgac acacaacttc acgcggagcg gcacgttccc cctggcgctg
     4321 gtgctgtcca gccgcgtgaa cagggcgcat tacttcacca gcatctgcgt ggagccagag
     4381 gtgggcaacg tcaccctgca gccagagagg cagtttgtgc agctcgggga cgaggcctgg
     4441 ctggtggcat gtgcctggcc cccgttcccc taccgctaca cctgggactt tggcaccgag
     4501 gaagccgccc ccacccgtgc caggggccct gaggtgacgt tcatctaccg agacccaggc
     4561 tcctatcttg tgacagtcac cgcgtccaac aacatctctg ctgccaatga ctcagccctg
     4621 gtggaggtgc aggagcccgt gctggtcacc agcatcaagg tcaatggctc ccttgggctg
     4681 gagctgcagc agccgtacct gttctctgct gtgggccgtg ggcgccccgc cagctacctg
     4741 tgggatctgg gggacggtgg gtggctcgag ggtccggagg tcacccacgc ttacaacagc
     4801 acaggtgact tcaccgttag ggtggccggc tggaatgagg tgagccgcag cgaggcctgg
     4861 ctcaatgtga cggtgaagcg gcgcgtgcgg gggctcgtcg tcaatgcaag ccgcacggtg
     4921 gtgcccctga atgggagcgt gagcttcagc acgtcgctgg aggccggcag tgatgtgcgc
     4981 tattcctggg tgctctgtga ccgctgcacg cccatccctg ggggtcctac catctcttac
     5041 accttccgct ccgtgggcac cttcaatatc atcgtcacgg ctgagaacga ggtgggctcc
     5101 gcccaggaca gcatcttcgt ctatgtcctg cagctcatag aggggctgca ggtggtgggc
     5161 ggtggccgct acttccccac caaccacacg gtacagctgc aggccgtggt tagggatggc
     5221 accaacgtct cctacagctg gactgcctgg agggacaggg gcccggccct ggccggcagc
     5281 ggcaaaggct tctcgctcac cgtgctcgag gccggcacct accatgtgca gctgcgggcc
     5341 accaacatgc tgggcagcgc ctgggccgac tgcaccatgg acttcgtgga gcctgtgggg
     5401 tggctgatgg tggccgcctc cccgaaccca gctgccgtca acacaagcgt caccctcagt
     5461 gccgagctgg ctggtggcag tggtgtcgta tacacttggt ccttggagga ggggctgagc
     5521 tgggagacct ccgagccatt taccacccat agcttcccca cacccggcct gcacttggtc
     5581 accatgacgg cagggaaccc gctgggctca gccaacgcca ccgtggaagt ggatgtgcag
     5641 gtgcctgtga gtggcctcag catcagggcc agcgagcccg gaggcagctt cgtggcggcc
     5701 gggtcctctg tgcccttttg ggggcagctg gccacgggca ccaatgtgag ctggtgctgg
     5761 gctgtgcccg gcggcagcag caagcgtggc cctcatgtca ccatggtctt cccggatgct
     5821 ggcaccttct ccatccggct caatgcctcc aacgcagtca gctgggtctc agccacgtac
     5881 aacctcacgg cggaggagcc catcgtgggc ctggtgctgt gggccagcag caaggtggtg
     5941 gcgcccgggc agctggtcca ttttcagatc ctgctggctg ccggctcagc tgtcaccttc
     6001 cgcctgcagg tcggcggggc caaccccgag gtgctccccg ggccccgttt ctcccacagc
     6061 ttcccccgcg tcggagacca cgtggtgagc gtgcggggca aaaaccacgt gagctgggcc
     6121 caggcgcagg tgcgcatcgt ggtgctggag gccgtgagtg ggctgcaggt gcccaactgc
     6181 tgcgagcctg gcatcgccac gggcactgag aggaacttca cagcccgcgt gcagcgcggc
     6241 tctcgggtcg cctacgcctg gtacttctcg ctgcagaagg tccagggcga ctcgctggtc
     6301 atcctgtcgg gccgcgacgt cacctacacg cccgtggccg cggggctgtt ggagatccag
     6361 gtgcgcgcct tcaacgccct gggcagtgag aaccgcacgc tggtgctgga ggttcaggac
     6421 gccgtccagt atgtggccct gcagagcggc ccctgcttca ccaaccgctc ggcgcagttt
     6481 gaggccgcca ccagccccag cccccggcgt gtggcctacc actgggactt tggggatggg
     6541 tcgccagggc aggacacaga tgagcccagg gccgagcact cctacctgag gcctggggac
     6601 taccgcgtgc aggtgaacgc ctccaacctg gtgagcttct tcgtggcgca ggccacggtg
     6661 accgtccagg tgctggcctg ccgggagccg gaggtggacg tggtcctgcc cctgcaggtg
     6721 ctgatgcggc gatcacagcg caactacttg gaggcccacg ttgacctgcg cgactgcgtc
     6781 acctaccaga ctgagtaccg ctgggaggtg tatcgcaccg ccagctgcca gcggccgggg
     6841 cgcccagcgc gtgtggccct gcccggcgtg gacgtgagcc ggcctcggct ggtgctgccg
     6901 cggctggcgc tgcctgtggg gcactactgc tttgtgtttg tcgtgtcatt tggggacacg
     6961 ccactgacac agagcatcca ggccaatgtg acggtggccc ccgagcgcct ggtgcccatc
     7021 attgagggtg gctcataccg cgtgtggtca gacacacggg acctggtgct ggatgggagc
     7081 gagtcctacg accccaacct ggaggacggc gaccagacgc cgctcagttt ccactgggcc
     7141 tgtgtggctt cgacacagag ggaggctggc gggtgtgcgc tgaactttgg gccccgcggg
     7201 agcagcacgg tcaccattcc acgggagcgg ctggcggctg gcgtggagta caccttcagc
     7261 ctgaccgtgt ggaaggccgg ccgcaaggag gaggccacca accagacggt gctgatccgg
     7321 agtggccggg tgcccattgt gtccttggag tgtgtgtcct gcaaggcaca ggccgtgtac
     7381 gaagtgagcc gcagctccta cgtgtacttg gagggccgct gcctcaattg cagcagcggc
     7441 tccaagcgag ggcggtgggc tgcacgtacg ttcagcaaca agacgctggt gctggatgag
     7501 accaccacat ccacgggcag tgcaggcatg cgactggtgc tgcggcgggg cgtgctgcgg
     7561 gacggcgagg gatacacctt cacgctcacg gtgctgggcc gctctggcga ggaggagggc
     7621 tgcgcctcca tccgcctgtc ccccaaccgc ccgccgctgg ggggctcttg ccgcctcttc
     7681 ccactgggcg ctgtgcacgc cctcaccacc aaggtgcact tcgaatgcac gggctggcat
     7741 gacgcggagg atgctggcgc cccgctggtg tacgccctgc tgctgcggcg ctgtcgccag
     7801 ggccactgcg aggagttctg tgtctacaag ggcagcctct ccagctacgg agccgtgctg
     7861 cccccgggtt tcaggccaca cttcgaggtg ggcctggccg tggtggtgca ggaccagctg
     7921 ggagccgctg tggtcgccct caacaggtct ttggccatca ccctcccaga gcccaacggc
     7981 agcgcaacgg ggctcacagt ctggctgcac gggctcaccg ctagtgtgct cccagggctg
     8041 ctgcggcagg ccgatcccca gcacgtcatc gagtactcgt tggccctggt caccgtgctg
     8101 aacgagtacg agcgggccct ggacgtggcg gcagagccca agcacgagcg gcagcaccga
     8161 gcccagatac gcaagaacat cacggagact ctggtgtccc tgagggtcca cactgtggat
     8221 gacatccagc agatcgctgc tgcgctggcc cagtgcatgg ggcccagcag ggagctcgta
     8281 tgccgctcgt gcctgaagca gacgctgcac aagctggagg ccatgatgct catcctgcag
     8341 gcagagacca ccgcgggcac cgtgacgccc accgccatcg gagacagcat cctcaacatc
     8401 acaggagacc tcatccacct ggccagctcg gacgtgcggg caccacagcc ctcagagctg
     8461 ggagccgagt caccatctcg gatggtggcg tcccaggcct acaacctgac ctctgccctc
     8521 atgcgcatcc tcatgcgctc ccgcgtgctc aacgaggagc ccctgacgct ggcgggcgag
     8581 gagatcgtgg cccagggcaa gcgctcggac ccgcggagcc tgctgtgcta tggcggcgcc
     8641 ccagggcctg gctgccactt ctccatcccc gaggctttca gcggggccct ggccaacctc
     8701 agtgacgtgg tgcagctcat ctttctggtg gactccaatc cctttccctt tggctatatc
     8761 agcaactaca ccgtctccac caaggtggcc tcgatggcat tccagacaca ggccggcgcc
     8821 cagatcccca tcgagcggct ggcctcagag cgcgccatca ccgtgaaggt gcccaacaac
     8881 tcggactggg ctgcccgggg ccaccgcagc tccgccaact ccgccaactc cgttgtggtc
     8941 cagccccagg cctccgtcgg tgctgtggtc accctggaca gcagcaaccc tgcggccggg
     9001 ctgcatctgc agctcaacta tacgctgctg gacggccact acctgtctga ggaacctgag
     9061 ccctacctgg cagtctacct acactcggag ccccggccca atgagcacaa ctgctcggct
     9121 agcaggagga tccgcccaga gtcactccag ggtgctgacc accggcccta caccttcttc
     9181 atttccccgg ggagcagaga cccagcgggg agttaccatc tgaacctctc cagccacttc
     9241 cgctggtcgg cgctgcaggt gtccgtgggc ctgtacacgt ccctgtgcca gtacttcagc
     9301 gaggaggaca tggtgtggcg gacagagggg ctgctgcccc tggaggagac ctcgccccgc
     9361 caggccgtct gcctcacccg ccacctcacc gccttcggcg ccagcctctt cgtgccccca
     9421 agccatgtcc gctttgtgtt tcctgagccg acagcggatg taaactacat cgtcatgctg
     9481 acatgtgctg tgtgcctggt gacctacatg gtcatggccg ccatcctgca caagctggac
     9541 cagttggatg ccagccgggg ccgcgccatc cctttctgtg ggcagcgggg ccgcttcaag
     9601 tacgagatcc tcgtcaagac aggctggggc cggggctcag gtaccacggc ccacgtgggc
     9661 atcatgctgt atggggtgga cagccggagc ggccaccggc acctggacgg cgacagagcc
     9721 ttccaccgca acagcctgga catcttccgg atcgccaccc cgcacagcct gggtagcgtg
     9781 tggaagatcc gagtgtggca cgacaacaaa gggctcagcc ctgcctggtt cctgcagcac
     9841 gtcatcgtca gggacctgca gacggcacgc agcgccttct tcctggtcaa tgactggctt
     9901 tcggtggaga cggaggccaa cgggggcctg gtggagaagg aggtgctggc cgcgagcgac
     9961 gcagcccttt tgcgcttccg gcgcctgctg gtggctgagc tgcagcgtgg cttctttgac
    10021 aagcacatct ggctctccat atgggaccgg ccgcctcgta gccgtttcac tcgcatccag
    10081 agggccacct gctgcgttct cctcatctgc ctcttcctgg gcgccaacgc cgtgtggtac
    10141 ggggctgttg gcgactctgc ctacagcacg gggcatgtgt ccaggctgag cccgctgagc
    10201 gtcgacacag tcgctgttgg cctggtgtcc agcgtggttg tctatcccgt ctacctggcc
    10261 atcctttttc tcttccggat gtcccggagc aaggtggctg ggagcccgag ccccacacct
    10321 gccgggcagc aggtgctgga catcgacagc tgcctggact cgtccgtgct ggacagctcc
    10381 ttcctcacgt tctcaggcct ccacgctgag gcctttgttg gacagatgaa gagtgacttg
    10441 tttctggatg attctaagag tctggtgtgc tggccctccg gcgagggaac gctcagttgg
    10501 ccggacctgc tcagtgaccc gtccattgtg ggtagcaatc tgcggcagct ggcacggggc
    10561 caggcgggcc atgggctggg cccagaggag gacggcttct ccctggccag cccctactcg
    10621 cctgccaaat ccttctcagc atcagatgaa gacctgatcc agcaggtcct tgccgagggg
    10681 gtcagcagcc cagcccctac ccaagacacc cacatggaaa cggacctgct cagcagcctg
    10741 tccagcactc ctggggagaa gacagagacg ctggcgctgc agaggctggg ggagctgggg
    10801 ccacccagcc caggcctgaa ctgggaacag ccccaggcag cgaggctgtc caggacagga
    10861 ctggtggagg gtctgcggaa gcgcctgctg ccggcctggt gtgcctccct ggcccacggg
    10921 ctcagcctgc tcctggtggc tgtggctgtg gctgtctcag ggtgggtggg tgcgagcttc
    10981 cccccgggcg tgagtgttgc gtggctcctg tccagcagcg ccagcttcct ggcctcattc
    11041 ctcggctggg agccactgaa ggtcttgctg gaagccctgt acttctcact ggtggccaag
    11101 cggctgcacc cggatgaaga tgacaccctg gtagagagcc cggctgtgac gcctgtgagc
    11161 gcacgtgtgc cccgcgtacg gccaccccac ggctttgcac tcttcctggc caaggaagaa
    11221 gcccgcaagg tcaagaggct acatggcatg ctgcggagcc tcctggtgta catgcttttt
    11281 ctgctggtga ccctgctggc cagctatggg gatgcctcat gccatgggca cgcctaccgt
    11341 ctgcaaagcg ccatcaagca ggagctgcac agccgggcct tcctggccat cacgcggtct
    11401 gaggagctct ggccatggat ggcccacgtg ctgctgccct acgtccacgg gaaccagtcc
    11461 agcccagagc tggggccccc acggctgcgg caggtgcggc tgcaggaagc actctaccca
    11521 gaccctcccg gccccagggt ccacacgtgc tcggccgcag gaggcttcag caccagcgat
    11581 tacgacgttg gctgggagag tcctcacaat ggctcgggga cgtgggccta ttcagcgccg
    11641 gatctgctgg gggcatggtc ctggggctcc tgtgccgtgt atgacagcgg gggctacgtg
    11701 caggagctgg gcctgagcct ggaggagagc cgcgaccggc tgcgcttcct gcagctgcac
    11761 aactggctgg acaacaggag ccgcgctgtg ttcctggagc tcacgcgcta cagcccggcc
    11821 gtggggctgc acgccgccgt cacgctgcgc ctcgagttcc cggcggccgg ccgcgccctg
    11881 gccgccctca gcgtccgccc ctttgcgctg cgccgcctca gcgcgggcct ctcgctgcct
    11941 ctgctcacct cggtgtgcct gctgctgttc gccgtgcact tcgccgtggc cgaggcccgt
    12001 acttggcaca gggaagggcg ctggcgcgtg ctgcggctcg gagcctgggc gcggtggctg
    12061 ctggtggcgc tgacggcggc cacggcactg gtacgcctcg cccagctggg tgccgctgac
    12121 cgccagtgga cccgtttcgt gcgcggccgc ccgcgccgct tcactagctt cgaccaggtg
    12181 gcgcagctga gctccgcagc ccgtggcctg gcggcctcgc tgctcttcct gcttttggtc
    12241 aaggctgccc agcagctacg cttcgtgcgc cagtggtccg tctttggcaa gacattatgc
    12301 cgagctctgc cagagctcct gggggtcacc ttgggcctgg tggtgctcgg ggtagcctac
    12361 gcccagctgg ccatcctgct cgtgtcttcc tgtgtggact ccctctggag cgtggcccag
    12421 gccctgttgg tgctgtgccc tgggactggg ctctctaccc tgtgtcctgc cgagtcctgg
    12481 cacctgtcac ccctgctgtg tgtggggctc tgggcactgc ggctgtgggg cgccctacgg
    12541 ctgggggctg ttattctccg ctggcgctac cacgccttgc gtggagagct gtaccggccg
    12601 gcctgggagc cccaggacta cgagatggtg gagttgttcc tgcgcaggct gcgcctctgg
    12661 atgggcctca gcaaggtcaa ggagttccgc cacaaagtcc gctttgaagg gatggagccg
    12721 ctgccctctc gctcctccag gggctccaag gtatccccgg atgtgccccc acccagcgct
    12781 ggctccgatg cctcgcaccc ctccacctcc tccagccagc tggatgggct gagcgtgagc
    12841 ctgggccggc tggggacaag gtgtgagcct gagccctccc gcctccaagc cgtgttcgag
    12901 gccctgctca cccagtttga ccgactcaac caggccacag aggacgtcta ccagctggag
    12961 cagcagctgc acagcctgca aggccgcagg agcagccggg cgcccgccgg atcttcccgt
    13021 ggcccatccc cgggcctgcg gccagcactg cccagccgcc ttgcccgggc cagtcggggt
    13081 gtggacctgg ccactggccc cagcaggaca ccccttcggg ccaagaacaa ggtccacccc
    13141 agcagcactt agtcctcctt cctggcgggg gtgggccgtg gagtcggagt ggacaccgct
    13201 cagtattact ttctgccgct gtcaaggccg agggccaggc agaatggctg cacgtaggtt
    13261 ccccagagag caggcagggg catctgtctg tctgtgggct tcagcacttt aaagaggctg
    13321 tgtggccaac caggacccag ggtcccctcc ccagctccct tgggaaggac acagcagtat
    13381 tggacggttt ctagcctctg agatgctaat ttatttcccc gagtcctcag gtacagcggg
    13441 ctgtgcccgg ccccaccccc tgggcagatg tcccccactg ctaaggctgc tggcttcagg
    13501 gagggttagc ctgcaccgcc gccaccctgc ccctaagtta ttacctctcc agttcctacc
    13561 gtactccctg caccgtctca ctgtgtgtct cgtgtcagta atttatatgg tgttaaaatg
    13621 tgtatatttt tgtatgtcac tattttcact agggctgagg ggcctgcgcc cagagctggc
    13681 ctcccccaac acctgctgcg cttggtaggt gtggtggcgt tatggcagcc cggctgctgc
    13741 ttggatgcga gcttggcctt gggccggtgc tgggggcaca gctgtctgcc aggcactctc
    13801 atcaccccag aggccttgtc atcctccctt gccccaggcc aggtagcaag agagcagcgc
    13861 ccaggcctgc tggcatcagg tctgggcaag tagcaggact aggcatgtca gaggacccca
    13921 gggtggttag aggaaaagac tcctcctggg ggctggctcc cagggtggag gaaggtgact
    13981 gtgtgtgtgt gtgtgtgcgc gcgcgcacgc gcgagtgtgc tgtatggccc aggcagcctc
    14041 aaggccctcg gagctggctg tgcctgcttc tgtgtaccac ttctgtgggc atggccgctt
    14101 ctagagcctc gacacccccc caacccccgc accaagcaga caaagtcaat aaaagagctg
    14161 tctgactgca a
//
