LOCUS       NM_001193621            1908 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens phospholipase A2 inhibitor and LY6/PLAUR domain
            containing (PINLYP), transcript variant 1, mRNA.
ACCESSION   NM_001193621 XM_001129773 XM_001131816 XM_001724340
VERSION     NM_001193621.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Loughner,C.L., Bruford,E.A., McAndrews,M.S., Delp,E.E.,
            Swamynathan,S. and Swamynathan,S.K.
  TITLE     Organization, evolution and functions of the human and mouse
            Ly6/uPAR family genes
  JOURNAL   Hum Genomics 10, 10 (2016)
   PUBMED   27098205
  REMARK    Review article
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            L34079.2 and AC006276.1.
            
            On Jun 26, 2021 this sequence version replaced NM_001193621.2.
            
            Transcript Variant: This variant (1) represents the longer variant
            and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.231439.1,
                                           SRR14038191.1168155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: downstream AUG is associated
                                                with N-terminal localization
                                                signal
            MANE Ensembl match               :: ENST00000599207.6/
                                                ENSP00000469886.1
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1119              L34079.2           2807-3925           c
            1120-1266           L34079.2           2465-2611           c
            1267-1383           L34079.2           1020-1136           c
            1384-1536           AC006276.1         2428-2580
            1537-1677           AC006276.1         2779-2919
            1678-1908           AC006276.1         3084-3314
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.31"
     gene            1..1908
                     /gene="PINLYP"
                     /note="phospholipase A2 inhibitor and LY6/PLAUR domain
                     containing"
                     /db_xref="GeneID:390940"
                     /db_xref="HGNC:HGNC:44206"
     exon            1..1119
                     /gene="PINLYP"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1266
                     /gene="PINLYP"
                     /inference="alignment:Splign:2.1.0"
     CDS             1197..1811
                     /gene="PINLYP"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; phospholipase A2 inhibitor and Ly6/PLAUR
                     domain-containing protein"
                     /codon_start=1
                     /product="phospholipase A2 inhibitor and Ly6/PLAUR
                     domain-containing protein isoform 1 precursor"
                     /protein_id="NP_001180550.2"
                     /db_xref="CCDS:CCDS74385.2"
                     /db_xref="GeneID:390940"
                     /db_xref="HGNC:HGNC:44206"
                     /translation="MRLSRRPETFLLAFVLLCTLLGLGCPLHCEICTAAGSRCHGQMK
                     TCSSDKDTCVLLVGKATSKGKELVHTYKGCIRSQDCYSGVISTTMGPKDHMVTSSFCC
                     QSDGCNSAFLSVPLTNLTENGLMCPACTASFRDKCMGPMTHCTGKENHCVSLSGHVQA
                     GIFKPRFAMRGCATESMCFTKPGAEVPTGTNVLFLHHIECTHSP"
     exon            1267..1383
                     /gene="PINLYP"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1536
                     /gene="PINLYP"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1677
                     /gene="PINLYP"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1908
                     /gene="PINLYP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1887..1892
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PINLYP"
                     /note="hexamer: TATAAA"
     polyA_site      1908
                     /gene="PINLYP"
                     /note="major polyA site"
ORIGIN      
        1 gtgtctggaa gaaattcgcc tttctcattg cacgatggag ttaccgccca cactgaagcc
       61 gagaaagcaa atctttttgc tgtattatta tttattttat tttttaaaaa ttttttgttg
      121 agacagggtc ttgctctctc acccaggatg gagtgcagtg gcacgatctc ggctttctgc
      181 aacccctgtc tcctggggcc aagggatcct cccacttcag cctcctaagt agctgggatt
      241 acacgcacgc gccaccacat tcggctaatt tttgtatttt ttgtggagac atggggtgag
      301 agggcggcgg gtcttgccat gttgcccaga ctggtctcga actcctcagc tcaagcgatc
      361 cacctgcctc ggcctctcaa agtgctggaa ctacaggcgt gagcgactgc gctgggctag
      421 gacagcaaat ctgagtgaat tttcgtagtt tcgtagggaa cctggattct acgcaacagg
      481 atctcttcaa atggctcagg cggctgcact cttctctctg tccccttgcc acacacacac
      541 acacgcacat atacatacat acgcgcgcgc gcacgcgcga aaaaaattag cagatctctt
      601 tcagccttat gcctgaggcc aaaagagaag ggttctgcgt cctaaatata acacaaagca
      661 tgtgcccaac ccccaccaca cacacacaca cacaccccta tcctggagtt cttccacaaa
      721 agcctcagtt tcccaatatg tggactgtgg gcatctgtct tttactacgc ccgcctatga
      781 ctgccgacag acatccctct gttcattcgg tgccttggag acccaagggt gcagccctgg
      841 gtggggtcgc agctggagac agcccaaaca cacaaggagt gtgagccgag cacatgaaga
      901 gaggggaagg gagacaaggc accccgcacc cgcaggacca gcctggacat gctgggtgct
      961 ccaaggtggg gccctaccca cactgggtgc ttccttggga ggagagggga agagagagaa
     1021 ggagagggaa tcccagttct tgcagccact gggaatcaag aggcccaact ccgtcttggt
     1081 cttcaagcaa acaaacaaac aacaatgggc cgtgggaagg gtgaatgtgg gtccagaccc
     1141 acccctcctc agcttcctat aaaagctggg gaccaggtac tgctgataca cacaccatga
     1201 ggctctccag gagaccagag acctttctgc tggcctttgt gttgctctgc accctcctgg
     1261 gtcttgggtg cccactacac tgcgaaatat gtacggcggc ggggagcagg tgccatggcc
     1321 aaatgaagac ctgcagcagt gacaaggaca catgtgtgct cctggtcggg aaggctactt
     1381 caaagggcaa ggagttggtg cacacctaca agggctgcat caggtcccag gactgctact
     1441 ccggcgttat atccaccacc atgggcccca aggaccacat ggtaaccagc tccttctgct
     1501 gccagagcga cggctgcaac agtgcctttt tgtctgttcc cttgaccaat cttactgaga
     1561 atggcctgat gtgccccgcc tgcactgcga gcttcaggga caaatgcatg gggcccatga
     1621 cccactgtac tggaaaggaa aaccactgcg tctccttatc tggacacgtg caggctggta
     1681 ttttcaaacc cagatttgct atgcggggct gtgctacaga gagtatgtgc tttaccaagc
     1741 ctggtgctga agtacccaca ggcaccaatg tcctcttcct ccatcatata gagtgcactc
     1801 actccccctg aaaagctatc tgaacagagg aagataatgt agtgtgaagt ccccatttgt
     1861 cctcagcctg taactccccg tgtgcctata aagaagttaa tagagcaa
//
