LOCUS       XM_047437436            7810 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens phosphatidylinositol glycan anchor
            biosynthesis class N (PIGN), transcript variant X16, mRNA.
ACCESSION   XM_047437436
VERSION     XM_047437436.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000018.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 40% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..7810
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
     gene            1..7810
                     /gene="PIGN"
                     /gene_synonym="MCAHS; MCAHS1; MCD4; MDC4; PIG-N"
                     /note="phosphatidylinositol glycan anchor biosynthesis
                     class N; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 40 ESTs, 700 long SRA
                     reads, 1 Protein, and 84% coverage of the annotated
                     genomic feature by RNAseq alignments, including 86 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:23556"
                     /db_xref="HGNC:HGNC:8967"
                     /db_xref="MIM:606097"
     CDS             323..3118
                     /gene="PIGN"
                     /gene_synonym="MCAHS; MCAHS1; MCD4; MDC4; PIG-N"
                     /codon_start=1
                     /product="GPI ethanolamine phosphate transferase 1 isoform
                     X6"
                     /protein_id="XP_047293392.1"
                     /db_xref="GeneID:23556"
                     /db_xref="HGNC:HGNC:8967"
                     /db_xref="MIM:606097"
                     /translation="MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAR
                     RLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALI
                     AGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYD
                     AKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGH
                     AHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHP
                     SETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGV
                     PFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKL
                     LSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIG
                     FVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTY
                     YVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRY
                     MLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAG
                     LLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPL
                     MNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLM
                     FVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAF
                     FGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLS
                     SKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQL
                     LTTKKLRLCGKPKSHFM"
ORIGIN      
        1 gagaattatc gcgatagcag cagcggccgg gcaggtattg ggggcgttcc ggaattgagg
       61 ggtggttgta gtggtggctt aggaataccc tcccggctat cgcttcagtg ggtagagggg
      121 accactgccc gagagcttta atggagctgg gtcctgcctt cgcgctgagg agccctcgtt
      181 ttcgagatca ggcctgaccg ggataagctc cagagattca ccaacaatag caaattacac
      241 actggcttgg aaagtactcc catgttccgt ttgatcttgg caatttaatg ctgttcttga
      301 agactaatta gttacactgg atatgctgct gttctttact ttgggattgc ttatacattt
      361 tgtgttcttc gcctccatct ttgacattta ttttacatct cctttggttc atggaatgac
      421 tcctcagttt acaccattgc ctcctccagc gagaagatta gtgttgtttg ttgctgatgg
      481 ccttcgagca gatgcacttt acgaattaga tgaaaatgga aactctagag caccgtttat
      541 taggaatatc ataatgcatg aaggcagctg gggcatatct catacacgtg tgccaacaga
      601 atctcggcca ggtcatgtag ctctgatagc tgggttttat gaagatgtca gtgcagttgc
      661 caaaggatgg aaggaaaatc ctgtagagtt tgattctctt tttaatgaaa gtaaatacac
      721 atggagctgg ggaagcccag atatcctgcc tatgtttgcc aaaggtgcta gtggagacca
      781 cgtttataca tatagttatg atgctaaaag agaggatttt ggtgctcaag atgcaacaaa
      841 actggatacg tgggtttttg ataatgttaa ggacttcttt catcatgcca gaaacaacca
      901 gtctttgttt tctaaaataa atgaagagaa aatagttttt ttcttacatt tattaggaat
      961 agatacaaac ggacatgctc atcgaccatc ctcgagagac tacaagcaca atattaaaaa
     1021 agttgatgat ggagttaaag aaatcgtgtc tatgtttaac cacttctatg gaaatgatgg
     1081 gaaaacaaca tttatcttta cctctgacca tggaatgaca gactggggtt cccatggggc
     1141 tggtcatcct tcagagactt taactccttt agtcacttgg ggagctggaa tcaagtatcc
     1201 ccaaagagta tcagctcagc aatttgatga tgcatttttg aaagagtgga gattggagaa
     1261 ttggaagagg ctagatgtca atcaggctga tattgcacca ttgatgactt cccttattgg
     1321 agttcccttt cctcttaact cagtgggaat ccttcctgtg gattatctta acaacactga
     1381 tctcttcaaa gcagagagca tgtttacaaa tgcagtacag attcttgaac agttcaaggt
     1441 gaaaatgact cagaagaaag aagttacttt accatttttg tttacaccat ttaaactgct
     1501 ttctgattcc aaacagttca acattttaag aaaagcaaga tcttatataa aacacagaaa
     1561 gtttgatgaa gtggtctccc tttgcaagga gctaattcat cttgcattga aaggattgtc
     1621 ctattatcac acatatgaca gattcttttt gggcgtcaat gttgttattg gttttgtggg
     1681 atggatatct tatgcctctt tgttgatcat caagtctcat tccaacctta taaaaggtgt
     1741 tagtaaagaa gtgaagaaac caagccatct cctgccttgt agttttgtag ctattggcat
     1801 tttagtagca ttttttctgc tgattcaagc ctgtccctgg acatattatg tatatggttt
     1861 gttgccactg ccaatatggt atgcggttct aagagaattt caagttattc aggaccttgt
     1921 tgtatcagtg ttgacctatc ctctgagcca ttttgttggg tacctgttag cctttaccct
     1981 gggaattgaa gtattagttc tcagtttttt ctaccgctat atgcttaccg ctggacttac
     2041 tgcctttgca gcttggccat ttctcactcg gctgtggact cgagcaaaga tgacctcact
     2101 gagttggact ttcttctctt tgctcctggc agtgttccca ctgatgccgg ttgtaggtcg
     2161 aaagccagac atctctctag tgatgggtgc aggcttgctg gttcttctgt tatccctgtg
     2221 tgttgtaaca tctctcatga aaagaaaaga tagctttata aaggaagagc tattggtaca
     2281 tctgttacag gtgctgagca cagtgctctc catgtatgtt gtgtatagca ctcagagtag
     2341 tctactcagg aagcaaggac tgcctctcat gaatcaaatt attagctggg caacattagc
     2401 ctcttccttg gttgtgccac tactgagttc tccagttctc tttcagcgat tgttcagcat
     2461 acttctttca ttgatgtcaa cctacctact tctaagcaca gggtatgaag ctctctttcc
     2521 actagtgttg tcttgtttga tgtttgtctg gataaacata gaacaagaaa ctctacaaca
     2581 atctggtgtt tgctgtaaac aaaagctcac cagtatccag ttctcttata atactgatat
     2641 aactcagttt cgacagctat atctggatga catccgtagg gcctttttcc ttgttttctt
     2701 cttagtgaca gcattttttg gaactggaaa tatagcttct attaacagct ttgatcttgc
     2761 ctctgtctat tgctttctga ctgtgttcag tccttttatg atgggagccc tgatgatgtg
     2821 gaagatttta atcccctttg ttcttgttat gtgtgctttt gaagcagttc agttgactac
     2881 tcagttatcg tcaaaaagcc tttttctcat tgttctcgtc atatcagaca ttatggcttt
     2941 gcattttttc ttcttggtca aggattatgg cagctggctt gatattggga caagcatcag
     3001 ccactatgtg attgtcatgt ccatgaccat ctttttggtg ttcctcaatg gcctggccca
     3061 gctgctcaca acgaagaaac tcagactatg tggcaaaccc aaaagtcact tcatgtgagg
     3121 ttgctgaagc accattcagc atctggatcc tgattctcct tttaagctaa aatctcatca
     3181 aggcttcaat aagaagatgg atatggatat atagtatatt ctactcctgt aaggaaaatg
     3241 gtatttggaa ttccgaattg acaggttatc tggaacaaag gagcttcttt ttttttctag
     3301 gttttgcagg catgaaatag tgattatatc tgtggaaaag cataggaagg cattctcctt
     3361 tttcattttt ttcctttggc tggcagctct tcccagtgat gttgagagca cctgcagcaa
     3421 tctggtcccc agtcgcacaa cttcccacat acccagagga gagcatatgc ctgtgggggc
     3481 agtgctgatg gcatccagag tcattgctgt ggctgagctg gaaggaaatc accaggtgcc
     3541 accgtcaata tttatcagct ttcagcactg gttttgttag acagtcaggg tgtattattt
     3601 caagagcttc aataaaaaaa gtgtttgcag gtatttgtca tatttcttta gtatgcaata
     3661 atgctatctt atccttttta gtgctatttc tcaggttttc tcagtcaacc agctagatgc
     3721 atgtgatgca tgtctatcct tcactttttt tttttcattt ctggattttc ctgggatttc
     3781 tgacaacaca aaagtagaaa gtgcttggta tttctgtctt atacatagga aaacatttaa
     3841 aataaatagt ttttaattgt aggctcaaca tctgttaccc catagctttt tcgtatattg
     3901 tttctttccc tttgaatttc tttttactgt catctattat tttaacagga gttaaaataa
     3961 ctcctgttaa actttctgac aatatcataa gaattcatat taaaggtgtt attctttctg
     4021 gttgtgagat tctagcacaa aggcctaaaa tcatcaaatt agatttccat ttgtaaacaa
     4081 attctaatgg gcaaaatatc ttgagagcag tttttatatg gattatccat aaaatgacct
     4141 ttacatatcc ctgcagagtt ggccttttgc ccgtggtgtg ctagtagctt tggctgatgc
     4201 taagctttcc tggtatgcgc cctattttta agaagtaatt gcttttgaat taagttatag
     4261 cattactaat tcatgttaat gactaggaaa ccctctgtaa tttacaagat ttttcaaatt
     4321 ggtggggagt gaataaatac aatttaaaag tcagaaatca gtttggcaaa gtgtactttc
     4381 ttaatttcta tttatgatga agtatagtca taatttattt gtaatactac tttatggtat
     4441 accagtgaaa gaactgtagt ataaaaaaga ggtattaatg ttttatgaaa tctcatgcat
     4501 cagttcatag cataaaatct agctggacaa ctaagaagct atggtagcaa acagtgatgt
     4561 tgatggaatg agaatcatga actttcatat tacctcaaag gattttttta tcagtttttt
     4621 tcacacatca gaaaaaactg actgtataaa cacttatcac tgaccttttt ctatgtgtag
     4681 ttttgccttt tatcttttcc caaattttta taaagagaaa ttaataaata ttttattaca
     4741 acattgtaaa gggtgctcag tttttttatc tttctttatt ttgctctttg aggcatatct
     4801 ttttcttaat tttgtccttt caggtcagtg tgagtctgta gaataggttg aacttccttc
     4861 tgacagtatc atagagtttg tggagtttgt gttgtgtgcc tgcagccaca ggctcgcctt
     4921 gctgcaccgt aactggcccc ttcagactca catgggaaca agccttttct gttgcagttt
     4981 cccagatatc tttaaatgtt ttgaaatgta tatttttatg ttgcaaaaca gaaaaaagaa
     5041 acgagttagg gaaaaagtat ttctatttaa ggtatttatt ttttcattct acctatgcca
     5101 tagatttctg aatcaagact taggacattt gctgattaac aatgtttaaa ttaggaattg
     5161 ttataagaat taaaataggc agaacaagtt gtgaaaatat tgaaccaaaa aaaggccatg
     5221 ctatcatctt agagggccca tgaataaacc ttagagggaa tcctaaggct ttaggaaacc
     5281 gctgcagctt gtctgtcatt ttccaatatg ttaattatta tacttagtgt acagtattta
     5341 gaatacaaaa tgctttttta ttttttagga aaataatgtt ataaatgatt gtatattttc
     5401 atagtaatgt ctttataatt atttattaat gatagagctg aattagaaaa gctcttcatc
     5461 cattataata tggtttctca tgaaaaactt attacaaatt tcagccaact cagatattaa
     5521 gaacatcagt gtcaatcctc ctcccctcct gcgacctttt tacacttgtt ttggtggact
     5581 aggggctcct tttctcctcc tttttgacat ataactgtgc cattaaaaac atgatttctg
     5641 atgaagctgg cctagaggga atgaaggaga ttgcgtgggt atggtctcta ggacaggcgt
     5701 agctgttgca gggccaccct gtccttggga gaacctggtg agctcccata ttcacactag
     5761 atgccatcat gtcagggggc tgaagagaat ggagctaatc aactctgtca tttggagaag
     5821 acccccttca gaccagttct gagaactcct tcttttaaga gaccagagat aacttgatca
     5881 tttctcacct tttcgtagtt gttctttttt atgttgacat tccccttact gtttttaaaa
     5941 tgcttcaaag cattaatgat tgttatgctg tgtgctttca gtactatggc aatatctttg
     6001 tagcattttc ccatttctgt ataagcatgg ttttttgttt tttttttttt cgtttttgtt
     6061 ttgagacagg gtctcactct tgttcaggct agaatgcagt ggcaccatct cagctcactg
     6121 caacctctgc ctcctgggct caagtgatcc tgccacctca gcctcctgag tagctgagac
     6181 tacaggcaca tgcccccaca cctagctaat tttaaaatat tttttgatgg agacagggtt
     6241 tcactatgtt ttccaggcag cagcattttt ttttgactgg gatttcttta tgatgctttg
     6301 ttatttaaaa aaaaaatgag aaggaaacat taataatcaa aattatcttt aattggcctc
     6361 acagggctaa aatctagaat tattattact cttgggtaaa ctcatgaaaa gtacttaata
     6421 ttcattctat aaagaaacaa aaagaacctt tgagatgtgt ctcttattca tttccttggg
     6481 tacacttaaa acgggttaca gttactgctc aactttctac cttcagaact gcagcattta
     6541 tttgccacac agcagcattt atcagagatt gtcccttaga acattggttc cttgtaatac
     6601 aaataaatgt cataataaaa atagtttctt ttttctttct ttcttttttt ttcaagacag
     6661 actctggctc tctcgccaag gctggaatgc agtggcgcaa tgtcagctca ctgcaagctc
     6721 cgcctccctg gttcaagcga ttcttctgcc tcagcctcct gagtagctgg gattacaggt
     6781 gcccaccacc acgtctggct aattttcata tttttagtac tgacaaggtt tcaccatgtt
     6841 tgtcaggctc atcttgaact cctgacctca agcagttcac ccgcctcggc ctcccaaagt
     6901 gctgggatta caggcgtgag ctgcctcacc cagctgaaaa gagtttctta attaaatata
     6961 tttgagaaac atctagtcaa accaccttaa ataggtatat ttacattagt tctaagggaa
     7021 tttaacttgt gatgtacgtt gtgaagggag gaagatagca ttatgccaaa agtttccact
     7081 agcttgacag cagaccctgt cttagagttt tcttcctgat tggtaaacat aagaaatgtt
     7141 tccaaagccg ggcttggtgg ctcacccctg taattccagc actttgggag gccgaggtgg
     7201 gtggatcact tgaggtcagg agttcgagac cagtctggcc aagatggcaa aaccccatct
     7261 ctactaaaca cacacacaca cacacacaca cacacacaca cacacacaca cacacacaca
     7321 cacacacaca cacccggcgg ggtggtaggc tcctgtaatc cttgctactc aggagcctga
     7381 ggcatgagaa ttgcttgaac ctgggaggtg gaatttgcaa tgagccgaga tggtgccact
     7441 ctgggcgaca aagtgagact ctgcctcaaa aagaaatgtc tccatataat tttgcactaa
     7501 aaccttaatt tgtcatagtt ttgaaaatag ggtgttgtat gttgattgaa tttttttccc
     7561 tgagaactgg aataccattt ttactttaac ccttaatgtg agaaaacttt acaatttcct
     7621 gcaatttttc ctgcctctgt atatattaca cctgtcatca tttagtcttt catgtgggaa
     7681 aggccagtgg taccagattg cattcggttc atcatggctc attgtctagc cctgctagag
     7741 tatagactaa gccttcatac cttatgtttt atatctttta cctgaaaaat aaatttgcac
     7801 caaatttcaa
//
