LOCUS       XM_047437435            7733 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens phosphatidylinositol glycan anchor
            biosynthesis class N (PIGN), transcript variant X15, mRNA.
ACCESSION   XM_047437435
VERSION     XM_047437435.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000018.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 40% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..7733
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
     gene            1..7733
                     /gene="PIGN"
                     /gene_synonym="MCAHS; MCAHS1; MCD4; MDC4; PIG-N"
                     /note="phosphatidylinositol glycan anchor biosynthesis
                     class N; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 41 ESTs, 1589 long SRA
                     reads, 1 Protein, and 84% coverage of the annotated
                     genomic feature by RNAseq alignments, including 152
                     samples with support for all annotated introns"
                     /db_xref="GeneID:23556"
                     /db_xref="HGNC:HGNC:8967"
                     /db_xref="MIM:606097"
     CDS             246..3041
                     /gene="PIGN"
                     /gene_synonym="MCAHS; MCAHS1; MCD4; MDC4; PIG-N"
                     /codon_start=1
                     /product="GPI ethanolamine phosphate transferase 1 isoform
                     X6"
                     /protein_id="XP_047293391.1"
                     /db_xref="GeneID:23556"
                     /db_xref="HGNC:HGNC:8967"
                     /db_xref="MIM:606097"
                     /translation="MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAR
                     RLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALI
                     AGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYD
                     AKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGH
                     AHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHP
                     SETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGV
                     PFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKL
                     LSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIG
                     FVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTY
                     YVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRY
                     MLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAG
                     LLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPL
                     MNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLM
                     FVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAF
                     FGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLS
                     SKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQL
                     LTTKKLRLCGKPKSHFM"
ORIGIN      
        1 gagaattatc gcgatagcag cagcggccgg gcaggtattg ggggcgttcc ggaattgagg
       61 ggtggttgta gtggtggctt aggaataccc tcccggctat cgcttcagtg ggtagagggg
      121 accactgccc gagagcttta atggagctgg gtcctgcctt cgcgctgagg agccctcgtt
      181 ttcgagatca ggcctgaccg ggataagctc cagctgttct tgaagactaa ttagttacac
      241 tggatatgct gctgttcttt actttgggat tgcttataca ttttgtgttc ttcgcctcca
      301 tctttgacat ttattttaca tctcctttgg ttcatggaat gactcctcag tttacaccat
      361 tgcctcctcc agcgagaaga ttagtgttgt ttgttgctga tggccttcga gcagatgcac
      421 tttacgaatt agatgaaaat ggaaactcta gagcaccgtt tattaggaat atcataatgc
      481 atgaaggcag ctggggcata tctcatacac gtgtgccaac agaatctcgg ccaggtcatg
      541 tagctctgat agctgggttt tatgaagatg tcagtgcagt tgccaaagga tggaaggaaa
      601 atcctgtaga gtttgattct ctttttaatg aaagtaaata cacatggagc tggggaagcc
      661 cagatatcct gcctatgttt gccaaaggtg ctagtggaga ccacgtttat acatatagtt
      721 atgatgctaa aagagaggat tttggtgctc aagatgcaac aaaactggat acgtgggttt
      781 ttgataatgt taaggacttc tttcatcatg ccagaaacaa ccagtctttg ttttctaaaa
      841 taaatgaaga gaaaatagtt tttttcttac atttattagg aatagataca aacggacatg
      901 ctcatcgacc atcctcgaga gactacaagc acaatattaa aaaagttgat gatggagtta
      961 aagaaatcgt gtctatgttt aaccacttct atggaaatga tgggaaaaca acatttatct
     1021 ttacctctga ccatggaatg acagactggg gttcccatgg ggctggtcat ccttcagaga
     1081 ctttaactcc tttagtcact tggggagctg gaatcaagta tccccaaaga gtatcagctc
     1141 agcaatttga tgatgcattt ttgaaagagt ggagattgga gaattggaag aggctagatg
     1201 tcaatcaggc tgatattgca ccattgatga cttcccttat tggagttccc tttcctctta
     1261 actcagtggg aatccttcct gtggattatc ttaacaacac tgatctcttc aaagcagaga
     1321 gcatgtttac aaatgcagta cagattcttg aacagttcaa ggtgaaaatg actcagaaga
     1381 aagaagttac tttaccattt ttgtttacac catttaaact gctttctgat tccaaacagt
     1441 tcaacatttt aagaaaagca agatcttata taaaacacag aaagtttgat gaagtggtct
     1501 ccctttgcaa ggagctaatt catcttgcat tgaaaggatt gtcctattat cacacatatg
     1561 acagattctt tttgggcgtc aatgttgtta ttggttttgt gggatggata tcttatgcct
     1621 ctttgttgat catcaagtct cattccaacc ttataaaagg tgttagtaaa gaagtgaaga
     1681 aaccaagcca tctcctgcct tgtagttttg tagctattgg cattttagta gcattttttc
     1741 tgctgattca agcctgtccc tggacatatt atgtatatgg tttgttgcca ctgccaatat
     1801 ggtatgcggt tctaagagaa tttcaagtta ttcaggacct tgttgtatca gtgttgacct
     1861 atcctctgag ccattttgtt gggtacctgt tagcctttac cctgggaatt gaagtattag
     1921 ttctcagttt tttctaccgc tatatgctta ccgctggact tactgccttt gcagcttggc
     1981 catttctcac tcggctgtgg actcgagcaa agatgacctc actgagttgg actttcttct
     2041 ctttgctcct ggcagtgttc ccactgatgc cggttgtagg tcgaaagcca gacatctctc
     2101 tagtgatggg tgcaggcttg ctggttcttc tgttatccct gtgtgttgta acatctctca
     2161 tgaaaagaaa agatagcttt ataaaggaag agctattggt acatctgtta caggtgctga
     2221 gcacagtgct ctccatgtat gttgtgtata gcactcagag tagtctactc aggaagcaag
     2281 gactgcctct catgaatcaa attattagct gggcaacatt agcctcttcc ttggttgtgc
     2341 cactactgag ttctccagtt ctctttcagc gattgttcag catacttctt tcattgatgt
     2401 caacctacct acttctaagc acagggtatg aagctctctt tccactagtg ttgtcttgtt
     2461 tgatgtttgt ctggataaac atagaacaag aaactctaca acaatctggt gtttgctgta
     2521 aacaaaagct caccagtatc cagttctctt ataatactga tataactcag tttcgacagc
     2581 tatatctgga tgacatccgt agggcctttt tccttgtttt cttcttagtg acagcatttt
     2641 ttggaactgg aaatatagct tctattaaca gctttgatct tgcctctgtc tattgctttc
     2701 tgactgtgtt cagtcctttt atgatgggag ccctgatgat gtggaagatt ttaatcccct
     2761 ttgttcttgt tatgtgtgct tttgaagcag ttcagttgac tactcagtta tcgtcaaaaa
     2821 gcctttttct cattgttctc gtcatatcag acattatggc tttgcatttt ttcttcttgg
     2881 tcaaggatta tggcagctgg cttgatattg ggacaagcat cagccactat gtgattgtca
     2941 tgtccatgac catctttttg gtgttcctca atggcctggc ccagctgctc acaacgaaga
     3001 aactcagact atgtggcaaa cccaaaagtc acttcatgtg aggttgctga agcaccattc
     3061 agcatctgga tcctgattct ccttttaagc taaaatctca tcaaggcttc aataagaaga
     3121 tggatatgga tatatagtat attctactcc tgtaaggaaa atggtatttg gaattccgaa
     3181 ttgacaggtt atctggaaca aaggagcttc tttttttttc taggttttgc aggcatgaaa
     3241 tagtgattat atctgtggaa aagcatagga aggcattctc ctttttcatt tttttccttt
     3301 ggctggcagc tcttcccagt gatgttgaga gcacctgcag caatctggtc cccagtcgca
     3361 caacttccca catacccaga ggagagcata tgcctgtggg ggcagtgctg atggcatcca
     3421 gagtcattgc tgtggctgag ctggaaggaa atcaccaggt gccaccgtca atatttatca
     3481 gctttcagca ctggttttgt tagacagtca gggtgtatta tttcaagagc ttcaataaaa
     3541 aaagtgtttg caggtatttg tcatatttct ttagtatgca ataatgctat cttatccttt
     3601 ttagtgctat ttctcaggtt ttctcagtca accagctaga tgcatgtgat gcatgtctat
     3661 ccttcacttt ttttttttca tttctggatt ttcctgggat ttctgacaac acaaaagtag
     3721 aaagtgcttg gtatttctgt cttatacata ggaaaacatt taaaataaat agtttttaat
     3781 tgtaggctca acatctgtta ccccatagct ttttcgtata ttgtttcttt ccctttgaat
     3841 ttctttttac tgtcatctat tattttaaca ggagttaaaa taactcctgt taaactttct
     3901 gacaatatca taagaattca tattaaaggt gttattcttt ctggttgtga gattctagca
     3961 caaaggccta aaatcatcaa attagatttc catttgtaaa caaattctaa tgggcaaaat
     4021 atcttgagag cagtttttat atggattatc cataaaatga cctttacata tccctgcaga
     4081 gttggccttt tgcccgtggt gtgctagtag ctttggctga tgctaagctt tcctggtatg
     4141 cgccctattt ttaagaagta attgcttttg aattaagtta tagcattact aattcatgtt
     4201 aatgactagg aaaccctctg taatttacaa gatttttcaa attggtgggg agtgaataaa
     4261 tacaatttaa aagtcagaaa tcagtttggc aaagtgtact ttcttaattt ctatttatga
     4321 tgaagtatag tcataattta tttgtaatac tactttatgg tataccagtg aaagaactgt
     4381 agtataaaaa agaggtatta atgttttatg aaatctcatg catcagttca tagcataaaa
     4441 tctagctgga caactaagaa gctatggtag caaacagtga tgttgatgga atgagaatca
     4501 tgaactttca tattacctca aaggattttt ttatcagttt ttttcacaca tcagaaaaaa
     4561 ctgactgtat aaacacttat cactgacctt tttctatgtg tagttttgcc ttttatcttt
     4621 tcccaaattt ttataaagag aaattaataa atattttatt acaacattgt aaagggtgct
     4681 cagttttttt atctttcttt attttgctct ttgaggcata tctttttctt aattttgtcc
     4741 tttcaggtca gtgtgagtct gtagaatagg ttgaacttcc ttctgacagt atcatagagt
     4801 ttgtggagtt tgtgttgtgt gcctgcagcc acaggctcgc cttgctgcac cgtaactggc
     4861 cccttcagac tcacatggga acaagccttt tctgttgcag tttcccagat atctttaaat
     4921 gttttgaaat gtatattttt atgttgcaaa acagaaaaaa gaaacgagtt agggaaaaag
     4981 tatttctatt taaggtattt attttttcat tctacctatg ccatagattt ctgaatcaag
     5041 acttaggaca tttgctgatt aacaatgttt aaattaggaa ttgttataag aattaaaata
     5101 ggcagaacaa gttgtgaaaa tattgaacca aaaaaaggcc atgctatcat cttagagggc
     5161 ccatgaataa accttagagg gaatcctaag gctttaggaa accgctgcag cttgtctgtc
     5221 attttccaat atgttaatta ttatacttag tgtacagtat ttagaataca aaatgctttt
     5281 ttatttttta ggaaaataat gttataaatg attgtatatt ttcatagtaa tgtctttata
     5341 attatttatt aatgatagag ctgaattaga aaagctcttc atccattata atatggtttc
     5401 tcatgaaaaa cttattacaa atttcagcca actcagatat taagaacatc agtgtcaatc
     5461 ctcctcccct cctgcgacct ttttacactt gttttggtgg actaggggct ccttttctcc
     5521 tcctttttga catataactg tgccattaaa aacatgattt ctgatgaagc tggcctagag
     5581 ggaatgaagg agattgcgtg ggtatggtct ctaggacagg cgtagctgtt gcagggccac
     5641 cctgtccttg ggagaacctg gtgagctccc atattcacac tagatgccat catgtcaggg
     5701 ggctgaagag aatggagcta atcaactctg tcatttggag aagaccccct tcagaccagt
     5761 tctgagaact ccttctttta agagaccaga gataacttga tcatttctca ccttttcgta
     5821 gttgttcttt tttatgttga cattcccctt actgttttta aaatgcttca aagcattaat
     5881 gattgttatg ctgtgtgctt tcagtactat ggcaatatct ttgtagcatt ttcccatttc
     5941 tgtataagca tggttttttg tttttttttt tttcgttttt gttttgagac agggtctcac
     6001 tcttgttcag gctagaatgc agtggcacca tctcagctca ctgcaacctc tgcctcctgg
     6061 gctcaagtga tcctgccacc tcagcctcct gagtagctga gactacaggc acatgccccc
     6121 acacctagct aattttaaaa tattttttga tggagacagg gtttcactat gttttccagg
     6181 cagcagcatt tttttttgac tgggatttct ttatgatgct ttgttattta aaaaaaaaat
     6241 gagaaggaaa cattaataat caaaattatc tttaattggc ctcacagggc taaaatctag
     6301 aattattatt actcttgggt aaactcatga aaagtactta atattcattc tataaagaaa
     6361 caaaaagaac ctttgagatg tgtctcttat tcatttcctt gggtacactt aaaacgggtt
     6421 acagttactg ctcaactttc taccttcaga actgcagcat ttatttgcca cacagcagca
     6481 tttatcagag attgtccctt agaacattgg ttccttgtaa tacaaataaa tgtcataata
     6541 aaaatagttt cttttttctt tctttctttt tttttcaaga cagactctgg ctctctcgcc
     6601 aaggctggaa tgcagtggcg caatgtcagc tcactgcaag ctccgcctcc ctggttcaag
     6661 cgattcttct gcctcagcct cctgagtagc tgggattaca ggtgcccacc accacgtctg
     6721 gctaattttc atatttttag tactgacaag gtttcaccat gtttgtcagg ctcatcttga
     6781 actcctgacc tcaagcagtt cacccgcctc ggcctcccaa agtgctggga ttacaggcgt
     6841 gagctgcctc acccagctga aaagagtttc ttaattaaat atatttgaga aacatctagt
     6901 caaaccacct taaataggta tatttacatt agttctaagg gaatttaact tgtgatgtac
     6961 gttgtgaagg gaggaagata gcattatgcc aaaagtttcc actagcttga cagcagaccc
     7021 tgtcttagag ttttcttcct gattggtaaa cataagaaat gtttccaaag ccgggcttgg
     7081 tggctcaccc ctgtaattcc agcactttgg gaggccgagg tgggtggatc acttgaggtc
     7141 aggagttcga gaccagtctg gccaagatgg caaaacccca tctctactaa acacacacac
     7201 acacacacac acacacacac acacacacac acacacacac acacacacac acacacccgg
     7261 cggggtggta ggctcctgta atccttgcta ctcaggagcc tgaggcatga gaattgcttg
     7321 aacctgggag gtggaatttg caatgagccg agatggtgcc actctgggcg acaaagtgag
     7381 actctgcctc aaaaagaaat gtctccatat aattttgcac taaaacctta atttgtcata
     7441 gttttgaaaa tagggtgttg tatgttgatt gaattttttt ccctgagaac tggaatacca
     7501 tttttacttt aacccttaat gtgagaaaac tttacaattt cctgcaattt ttcctgcctc
     7561 tgtatatatt acacctgtca tcatttagtc tttcatgtgg gaaaggccag tggtaccaga
     7621 ttgcattcgg ttcatcatgg ctcattgtct agccctgcta gagtatagac taagccttca
     7681 taccttatgt tttatatctt ttacctgaaa aataaatttg caccaaattt caa
//
