LOCUS       XM_011528060            3568 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein inhibitor of activated STAT 4
            (PIAS4), transcript variant X1, mRNA.
ACCESSION   XM_011528060
VERSION     XM_011528060.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011528060.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3568
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..3568
                     /gene="PIAS4"
                     /gene_synonym="PIAS-gamma; Piasg; PIASY; ZMIZ6"
                     /note="protein inhibitor of activated STAT 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 47 ESTs, 269 long SRA reads, 2 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 10 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:51588"
                     /db_xref="HGNC:HGNC:17002"
                     /db_xref="MIM:605989"
     CDS             468..2057
                     /gene="PIAS4"
                     /gene_synonym="PIAS-gamma; Piasg; PIASY; ZMIZ6"
                     /codon_start=1
                     /product="E3 SUMO-protein ligase PIAS4 isoform X1"
                     /protein_id="XP_011526362.1"
                     /db_xref="GeneID:51588"
                     /db_xref="HGNC:HGNC:17002"
                     /db_xref="MIM:605989"
                     /translation="MTSSLPAKALGHFQKKHLVCKPFCFLHKNMVMSFRVSDLQMLLG
                     FVGRSKSGLKHELVTRALQLVQFDCSPELFKKIKELYETRYAKKNSEPAPQPHRPLDP
                     LTMHSTYDRAGAVPRTPLAGPNIDYPVLYGKYLNGLGRLPAKTLKPEVRLVKLPFFNM
                     LDELLKPTELVPQNNEKLQESPCIFALTPRQVELIRNSRELQPGVKAVQVVLRICYSD
                     TSCPQEDQYPPNIAVKVNHSYCSVPGYYPSNKPGVEPKRPCRPINLTHLMYLSSATNR
                     ITVTWGNYGKSYSVALYLVRQLTSSELLQRLKTIGVKHPELCKALVKEKLRLDPDSEI
                     ATTGVRVSLICPLVKMRLSVPCRAETCAHLQCFDAVFYLQMNEKKPTWMCPVCDKPAP
                     YDQLIIDGLLSKILSECEDADEIEYLVDGSWCPIRAEKERSCSPQGAILVLGPSDANG
                     LLPAPSVNGSGALGSTGGGGPVGSMENGKPGADVVDLTLDSSSSSEDEEEEEEEEEDE
                     DEEGPRPKRRCPFQKGLVPAC"
ORIGIN      
        1 gcgccttcct gagctacccc cggtgctctg aggggcctat gctggaggaa aggttcagcg
       61 cagctgctgt gtctcggctg atgtctcccc atgcgacttc caggcaagcc tggagttgaa
      121 actctggaag ctgccggggc ctggcactgt ttataaacac agctctgacg gcaagcaggt
      181 cagcttgaag ccagggcagg aagtgatctt ggggcatttg gggcttcttc ctgaatgctt
      241 gtcccccccg cactccctcc agtgtcaagg gcaggctcct ccgaggtggc agctgctggg
      301 aaatctgagt cgtgaacata tggccaccta aggggtgtgc tccgggaagc gggagctgcg
      361 gctccactgt ccagcctggg tggggcaggg gctcccgggg tgcgaggatg tcagcaggtt
      421 ccccagccca cctgccttcg gccagtctgc cagtgtgaag tgtccacatg acatcgtctc
      481 tccctgctaa ggctttgggc cacttccaga agaaacatct tgtctgcaag cctttttgtt
      541 ttctgcacaa gaacatggtg atgagttttc gagtctccga ccttcagatg ctcctgggtt
      601 tcgtgggccg gagtaagagt ggactgaagc acgagctcgt caccagggcc ctccagctgg
      661 tgcagtttga ctgtagccct gagctgttca agaagatcaa ggagctgtac gagacccgct
      721 acgccaagaa gaactcggag cctgccccac agccgcaccg gcccctggac cccctgacca
      781 tgcactccac ctacgaccgg gccggcgctg tgcccaggac tccgctggca ggccccaata
      841 ttgactaccc cgtgctctac ggaaagtact taaacggact gggacggttg cccgccaaga
      901 ccctcaagcc agaagtccgc ctggtgaagc tgccgttctt taatatgctg gatgagctgc
      961 tgaagcccac cgaattagtc ccacagaaca acgagaagct tcaggagagc ccgtgcatct
     1021 tcgcattgac gccaagacag gtggagttga tccggaactc cagggaactg cagcccggag
     1081 ttaaagccgt gcaggtcgtc ctgagaatct gttactcaga caccagctgc cctcaggagg
     1141 accagtaccc gcccaacatc gctgtgaagg tcaaccacag ctactgctcc gtcccgggct
     1201 actacccctc caataagccc ggggtggagc ccaagaggcc gtgccgcccc atcaacctca
     1261 cccacctcat gtacctgtcc tcggccacca accgcatcac tgtcacctgg gggaactacg
     1321 gcaagagcta ctcggtggcc ctgtacctgg tgcggcagct gacctcatcg gagctgctgc
     1381 agaggctgaa gaccattggg gtaaagcacc cggagctgtg caaggcactg gtcaaggaga
     1441 agctgcgcct tgatcctgac agcgagatcg ccaccaccgg tgtgcgggtg tccctcatct
     1501 gtccgctggt gaagatgcgg ctctccgtgc cctgccgggc agagacctgt gcccacctgc
     1561 agtgcttcga cgccgtcttc tacctgcaga tgaacgagaa gaagcccacc tggatgtgcc
     1621 ccgtgtgcga caagccagcc ccctacgacc agctcatcat cgacgggctc ctctcgaaga
     1681 tcctgagcga gtgtgaggac gccgacgaga tcgagtacct ggtggacggc tcgtggtgcc
     1741 cgatccgcgc cgaaaaggag cgcagctgca gcccgcaggg cgccatcctc gtgctgggcc
     1801 cctcggacgc caatgggctc ctgcccgccc ccagcgtcaa cgggagcggt gccctgggca
     1861 gcacgggtgg cggcggcccg gtgggcagca tggagaatgg gaagccgggc gccgatgtgg
     1921 tggacctcac gctggacagc tcatcgtcct cggaggatga ggaggaggag gaagaggagg
     1981 aggaagacga ggacgaagag gggccccggc ccaagcgccg ctgccccttc cagaagggcc
     2041 tggtgccggc ctgctgaccc cggccgcaca ctcgactttc ctggtgctca ccacgcagag
     2101 gggcacgggc cagcctcggg cgcagaggga ggagtgacct ttctttttct ttttattgtc
     2161 gttcgttttg tttttccacc cttttgcctg gctcctggca cctgtacctc tggactctcc
     2221 tatcggggga ttaaaaaaaa aagtaaaatg acaaaaaaag atacaaaaaa gaaaaatgaa
     2281 acaaaaaagt caaactctta aaaacaaggc cggccaccca cacagccgcc tccccggctg
     2341 gagtccgagc cgggaagggg tagtgggcgg gagggaccag gacgccgccc cgcgccctcc
     2401 cctccggatg ccccgccgcc cgccgccctc tgcccacgac cattccagcc agtgcgcggg
     2461 gacccgggcg gcgggcggtg gggcgcagcc cctctctggc gaccactttg acgtttgtct
     2521 cttcctttgc tttttctctg caaatgcatc ctcgcccaga gaccctcacg cgccgagcag
     2581 cgagcgtttt agccgagaag ccatggagtg ggttggggcg gggaggggca gtagggtggg
     2641 gggatgggtg ggcaggatgg gggtacagtg ggcggctggg gagggtttag ccacagatgt
     2701 gttgtatttt ttgaaagtgc aataatttgg tattttgaag acccggcgtg tggtcaggaa
     2761 cccccgggga aggcgggggc ccagggtgcg gcaccgtgtg gcgtgggggg gtctcagttt
     2821 tctagccagc tacctcggta attccaattc aggttaactt ccctacggaa cagcacagat
     2881 gtccacagat gtccacagct gccgccgccg ccgccgccac cataccccgg tccttggggc
     2941 atgggttgcg gtcgcttccc aaggggcagc agggaccccg gccaccccgg ctctcggttt
     3001 gggttgattc ctctcctttt tgctcttggt tttccgacgg gtacgaggct ggcccggcac
     3061 cctgtccccc gggagcctca ctcttccagc aggaccagac caggggcctc cttcctgtcc
     3121 ccaggcgttc ccggcccctc gcaggcccca cccatgccct tggcctcagg gtccaacaac
     3181 tgggggagct accagggctc tgccttcagg agcccacagc tgggcacccc ccttgccccg
     3241 caggagaccg gggcgcaggc ggggcaccgg cctcacctgg ttctccaaca ccgctgcctg
     3301 cggtctgttt tgcttttgtc ctccccagcc cagaattttc ctttgtataa acagaactcc
     3361 tagtcaggaa gcaatatcat ttcaggtcta aagaaaggga cgtgcatctg gccgagggca
     3421 gttcagtctc actgcagagc ccgcagcccg ctgcgcagct cggcccctcc cgcccgcacg
     3481 ggcagctgaa ggccgctgtt ttctaatatt tgtattctaa tttaattgtt tttaaaaaat
     3541 gcaaataaaa aaggtcgagg tgaagcca
//
