LOCUS       XM_047426645            5014 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens pleckstrin homology like domain family B
            member 1 (PHLDB1), transcript variant X43, mRNA.
ACCESSION   XM_047426645
VERSION     XM_047426645.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000011.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5014
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
     gene            1..5014
                     /gene="PHLDB1"
                     /gene_synonym="LL5A; LL5alpha; OI23"
                     /note="pleckstrin homology like domain family B member 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 91 ESTs, 520 long SRA reads, 4
                     Proteins, and 99% coverage of the annotated genomic
                     feature by RNAseq alignments, including 84 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:23187"
                     /db_xref="HGNC:HGNC:23697"
                     /db_xref="MIM:612834"
     CDS             168..3809
                     /gene="PHLDB1"
                     /gene_synonym="LL5A; LL5alpha; OI23"
                     /codon_start=1
                     /product="pleckstrin homology-like domain family B member
                     1 isoform X37"
                     /protein_id="XP_047282601.1"
                     /db_xref="GeneID:23187"
                     /db_xref="HGNC:HGNC:23697"
                     /db_xref="MIM:612834"
                     /translation="MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPESES
                     LVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLS
                     PMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSV
                     PPLVPARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATV
                     LAEARRATESPRLGGQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGT
                     LQDRPPSPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMR
                     ELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARG
                     RRTRSPSPTLGESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPV
                     TRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADG
                     GPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENL
                     KEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA
                     REAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETK
                     LFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQ
                     AVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEVYRSKMD
                     GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAA
                     TLQDIETKRQLALQQKVESLPAEPLPTDDPAGQQVIEEQRRRLAELKQKAAAEAQCQW
                     DALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSIS
                     TGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEE
                     RRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIES
                     SGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLK
                     GVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTG
                     AEGYTQFMN"
ORIGIN      
        1 cctccccggg cattggcggc tgctcgctgc ctcgctgctc gctccgagcc tagagccggc
       61 agctcgggag gtcggcccgc cccctcaaag gctccgggcg ggcccgggac ctggagggcc
      121 cgagctagcg ggggcgagcg gtccggaggt ccggtttcgg cggctgcatg ttgtgcctgg
      181 gtcagtccac cttccttcgc tttaaccacc cggctgaagc caagtggatg aaaagcatga
      241 ttccagcagg gggccgagcc cctgggcccc cctacagccc tgttcctgaa tcagaaagtc
      301 tggtaaatgg gaaccacacc ccacagactg caacacgggg accctctgcc tgtgccagcc
      361 acagttccct ggtgagctct attgagaagg acctgcaaga gatcatggac tcactggtgc
      421 tagaggagcc tggagctgct ggcaagaagc ctgccgcaac ctctccactg tcaccgatgg
      481 ctaatggtgg gcgctacctg ctgtctcccc caaccagccc cggcgccatg tctgtgggct
      541 ccagctatga gaacacctct ccagccttct ctccactctc ttcaccagcc agcagtggaa
      601 gctgtgccag tcactcaccc agtgggcaag agccaggacc ttctgtgccc ccgctggtac
      661 ctgcccgttc ctccagctac catctggccc tacagccccc acagtcccgc ccaagtggtg
      721 ctcgctccga gagtcctcgg ctgagcagga aagggggcca tgagaggcct cccagccctg
      781 gcctccgggg tctgctgaca gacagccctg cagctactgt cttggcggag gcccggagag
      841 ccactgagag cccccggctg ggtgggcagc tgcctgtggt ggccatcagc ctgagtgaat
      901 acccagcttc tggtgctctc agtcaaccca ccagcattcc tggcagcccc aagtttcagc
      961 ctccagtccc tgctccccga aacaagattg gcacactcca ggaccgccct cccagccctt
     1021 tccgtgagcc tccaggcagt gagcgggtgc taacaaccag cccctcacgc caactggtgg
     1081 gccgaacatt ttcagatggg ttagccaccc gtaccctgca gcctcctgag agtccccgcc
     1141 tgggccggcg gggcctggac agtatgcgag aactaccccc cttaagtcca tctctgtccc
     1201 ggcgagctct ctccccgctg cccacccgga ccaccccaga tcccaagcta aacagggaag
     1261 tggcagagag tcctcggccc cggcgctggg cagcccatgg ggcttcacca gaggacttct
     1321 ccctgacgct gggggcacgg ggccgtagga cacggagccc ctcacccaca ctgggtgagt
     1381 ctctggcacc ccacaagggc agcttcagtg gcaggctgag cccagcctac agtctgggct
     1441 ctcttactgg ggcttcaccc tgccagagtc cctgtgtcca gaggaagctc tccagcgggg
     1501 acttgcgggt gcctgtcaca agggagcgga aaaatagcat cacagagatc agtgacaatg
     1561 aggacgacct cctggagtac caccggcgac agcgccaaga gcggctccgg gagcaggaga
     1621 tggagaggct ggaacgccag cgcctggaga ccatcctgaa cctgtgtgcc gaatacagcc
     1681 gggctgatgg gggacctgag gctggggagc ttcccagcat tggggaggcc accgcagcat
     1741 tggcactggc aggccggagg ccctcacgag gccttgcagg ggcctctggg cggagcagcg
     1801 aggagcctgg cgttgccacc caacgcctat gggagagtat ggagcgctca gatgaggaaa
     1861 atctcaagga ggagtgcagc agcactgaga gcacccagca ggagcacgaa gatgcaccta
     1921 gcaccaagct ccagggagag gtgctagccc tggaagaaga gcgggctcag gtgctggggc
     1981 acgtggagca gctcaaggtc cgtgtgaagg agctagagca gcagctgcag gagtcagccc
     2041 gagaggccga aatggagcgg gcactgctgc agggagagag ggaggcagag cgggcactgc
     2101 tgcagaagga gcagaaggca gtggatcagc tgcaggagaa gctggtggcc ttggagacag
     2161 gcatccagaa ggagagggac aaggaggcag aggccctgga gactgagaca aagctctttg
     2221 aggacttgga gttccagcag ttggagcggg agagccgcgt ggaggaggag cgcgagctgg
     2281 ccggccaggg gctgctccgg agcaaggctg agctgctccg cagcatcgcc aagaggaagg
     2341 agcgcctggc catcctggac agtcaggctg ggcagatccg ggctcaggcc gtgcaggaat
     2401 cagaacgcct ggcccgggac aagaatgcct ccttacagct gctgcaaaag gagaaggaga
     2461 agctgactgt gctggaaagg agataccact cactcacagg gggcaggcct ttcccgaaga
     2521 ccacatcgac cctcaaagag gtttaccgct ccaagatgga tggcgaggcc accagccccc
     2581 ttccccggac ccgcagcggc cccctcccct cctcctctgg ctcttcctcc tcctcctccc
     2641 agctcagcgt ggctaccctg gggcgtagcc cctccccaaa gagcgctcta ctcacccaga
     2701 atggcacggg cagccttcct cgcaacctgg cagccacact gcaggacatc gagaccaagc
     2761 gccaactagc tctgcagcag aaggtcgagt cgcttcccgc cgagcccctc ccaaccgacg
     2821 acccagcagg acaacaagtg attgaagagc agcggcggcg actggctgag ctgaagcaga
     2881 aagcggcagc tgaggcacag tgccagtggg atgcccttca cggggcagca cccttcccag
     2941 cgggcccctc gggcttcccc cctctcatgc accactctat cctacaccac ctgcctgcgg
     3001 ggcgggagcg tggggaggag ggtgagcacg cctatgatac gctgagtctg gagagctctg
     3061 acagcatgga gaccagcatc tccaccgggg gcaactcggc ctgctcccct gacaacatgt
     3121 ccagcgcgag tggtctggac atggggaaga tcgaggagat ggagaagatg ctgaaagagg
     3181 ctcatgcaga gaagaaccgg ctcatggagt cgagggagcg ggagatggag ctgcggcggc
     3241 aggccctgga ggaggagcgg cggaggcgtg agcaggtaga acggaggctg cagagtgaga
     3301 gtgcccggag gcagcagctg gtcgagaagg aggtcaagat gcgggagaaa caattttccc
     3361 aggcacgacc cctgacccgc tacctgccaa tccggaagga ggactttgac ctgaagacac
     3421 atattgagtc atcgggccat ggtgttgata cctgcctgca cgtggtgctc agcagcaagg
     3481 tctgccgtgg ctacttggtc aagatgggcg gcaagattaa atcatggaag aagcgctggt
     3541 ttgtcttcga ccggctcaag cgcacccttt cctattatgt ggacaagcat gagacgaagc
     3601 tgaagggagt catctatttc caggccattg aggaagtgta ctacgaccac ctgcgcagtg
     3661 cagccaagag cccgaaccca gccctcacct tctgcgtaaa gacccatgac cggctgtact
     3721 acatggtggc cccatctgca gaggccatgc gtatctggat ggatgtcatt gtcacagggg
     3781 ctgagggcta cactcagttc atgaactaac tgccgtgggc ctcctggcag agcacaactg
     3841 gggcttttgt ataagaagac tttaatattc tgtaaggagc ttggtcctgt gagtttctgg
     3901 gctctggcct cctgaagaac cagccagaag aagaaaagta gaggtggctt tgctgcctcc
     3961 tgggagccca gaacttgcag taacccttta gggtcctgcc ccaggcccag ccagggctga
     4021 ggagctgtca cagagagggc ctcagctctg acctgacacc tgctctcccc agcctgtttt
     4081 ctcttttcta aaagacaaat tatggtacca taagctgcca aagatcccct cctgcctcag
     4141 acccctttgc caggggcttt gggggctgag cagagccaca tccagagtgg ggtaatagct
     4201 caggcggccc gcttcccatt tctcaaaccc cgctctgccc cattgttctc ctttccctta
     4261 tactttttat taccttgctc aagggccaga gatctcaagt gtcaaccttg aggtcccagc
     4321 tccatcccct agttgcagac tcatcaccat ggttaccata gtgactgctt cattgccatg
     4381 gttacatact aattgctgca gctctgtggc ccagcccact gcttcagctg tgggccatct
     4441 gagggtacgt gccatcatct ctccagccca ggcccctggg catctcatgc tggggggaag
     4501 ggactgaata cctttttcct tccccctgcc tgtgtcttca gccctgatgc acaggctgcc
     4561 agccccccag tccagccctc tcccttccac tggtgccttg cttagagcca gaagggatga
     4621 agccggggga tctatggaac agaggaggag cgatgcagtt gggagaggaa gctagaaggg
     4681 ttatggttgg agttctgtac agtgttgagt ttccgacagg gaaagaggat tcctccaatg
     4741 ctcctagaga gaaagcctga gcaggagatg atgcagcaga ggggaagggc cctgtggtgc
     4801 cgccgccctt ccttcagcct ccgaagggtg atggaaatgg agagtggagg accaggcctc
     4861 cagctgtctg gcctcgccct tcacgcctta acactaagcc cacctcccct gctctccttc
     4921 ccagcattga gcccttggtt gcctgggccc aggctggggg ttttcagtat ttgtaagcat
     4981 ttcagcagaa caataaagcc tttggactac ggaa
//
