LOCUS       NM_001145643             436 bp    mRNA    linear   PRI 01-AUG-2024
DEFINITION  Homo sapiens proline, histidine and glycine rich 1 (PHGR1), mRNA.
ACCESSION   NM_001145643 XR_040288 XR_040289 XR_040290
VERSION     NM_001145643.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Oltedal,S., Skaland,I., Maple-Grodem,J., Tjensvoll,K.,
            Janssen,E.A.M., Gilje,B., Smaaland,R., Heikkila,R. and Nordgard,O.
  TITLE     Expression profiling and intracellular localization studies of the
            novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an
            essential role in gastro-intestinal epithelium and a potential
            clinical application in colorectal cancer diagnostics
  JOURNAL   BMC Gastroenterol 18 (1), 26 (2018)
   PUBMED   29415677
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BM854696.1 and BC061640.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001145643.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BM854696.1, BM766981.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000448599.2/ ENSP00000410024.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                BM854696.1         1-12
            13-436              BC061640.1         1-424
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q15.1"
     gene            1..436
                     /gene="PHGR1"
                     /note="proline, histidine and glycine rich 1"
                     /db_xref="GeneID:644844"
                     /db_xref="HGNC:HGNC:37226"
     exon            1..30
                     /gene="PHGR1"
                     /inference="alignment:Splign:2.1.0"
     exon            31..66
                     /gene="PHGR1"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..305
                     /gene="PHGR1"
                     /note="proline/histidine/glycine-rich 1;
                     proline-histidine-glycin-rich protein 1"
                     /codon_start=1
                     /product="proline, histidine and glycine-rich protein 1"
                     /protein_id="NP_001139115.1"
                     /db_xref="CCDS:CCDS45225.1"
                     /db_xref="GeneID:644844"
                     /db_xref="HGNC:HGNC:37226"
                     /translation="MDPGPKGHCHCGGHGHPPGHCGPPPGHGPGPCGPPPHHGPGPCG
                     PPPGHGPGPCGPPPHHGPGPCGPPPGHGPGHPPPGPHH"
     exon            67..74
                     /gene="PHGR1"
                     /inference="alignment:Splign:2.1.0"
     exon            75..436
                     /gene="PHGR1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      398..403
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHGR1"
                     /note="hexamer: AATAAA"
     polyA_site      436
                     /gene="PHGR1"
                     /note="major polyA site"
ORIGIN      
        1 agacttcctg cccctgctct gcactctcag gtattccctg ctcttactcc aaaaagatgg
       61 acccaggtcc gaaggggcac tgccactgtg gggggcatgg ccatcctcca ggtcactgcg
      121 ggccaccccc tggccatggc ccagggccct gcgggccacc cccccaccat ggtccagggc
      181 cctgcgggcc accccctggc catggcccag ggccctgcgg gccacccccc caccatggtc
      241 cagggccctg cgggcctccc cctggccatg gcccaggtca cccaccccct ggtccacatc
      301 actgaggaag tagaagaaaa caggacacaa gatggcaagc ctgagagaat tgcccagctg
      361 acctggaatg aggcctaaac cacaatcttc tcttcctaat aaacagcctc ctagaggcca
      421 cattctattc tttaaa
//
