LOCUS       NM_001370348           18797 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens PHD finger protein 3 (PHF3), transcript variant 4,
            mRNA.
ACCESSION   NM_001370348 XM_005248701
VERSION     NM_001370348.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 18797)
  AUTHORS   Appel,L.M., Franke,V., Bruno,M., Grishkovskaya,I.,
            Kasiliauskaite,A., Kaufmann,T., Schoeberl,U.E., Puchinger,M.G.,
            Kostrhon,S., Ebenwaldner,C., Sebesta,M., Beltzung,E., Mechtler,K.,
            Lin,G., Vlasova,A., Leeb,M., Pavri,R., Stark,A., Akalin,A.,
            Stefl,R., Bernecky,C., Djinovic-Carugo,K. and Slade,D.
  TITLE     PHF3 regulates neuronal gene expression through the Pol II CTD
            reader domain SPOC
  JOURNAL   Nat Commun 12 (1), 6078 (2021)
   PUBMED   34667177
  REMARK    GeneRIF: PHF3 regulates neuronal gene expression through the Pol II
            CTD reader domain SPOC.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18797)
  AUTHORS   Zuo,L., Wang,K., Wang,G., Pan,X., Zhang,X., Zhang,H. and Luo,X.
  TITLE     Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence
  JOURNAL   Am J Addict 23 (4), 411-414 (2014)
   PUBMED   24961364
  REMARK    GeneRIF: We confirmed with our previous findings that
            PTP4A1-PHF3-EYS variants were significantly associated with alcohol
            dependence.
REFERENCE   3  (bases 1 to 18797)
  AUTHORS   Zuo,L., Zhang,X., Deng,H.W. and Luo,X.
  TITLE     Association of rare PTP4A1-PHF3-EYS variants with alcohol
            dependence
  JOURNAL   J Hum Genet 58 (3), 178-179 (2013)
   PUBMED   23324950
  REMARK    GeneRIF: PTP4A1-PHF3-EYS variants were associated with alcohol
            dependence.
REFERENCE   4  (bases 1 to 18797)
  AUTHORS   Zuo,L., Zhang,C.K., Wang,F., Li,C.S., Zhao,H., Lu,L., Zhang,X.Y.,
            Lu,L., Zhang,H., Zhang,F., Krystal,J.H. and Luo,X.
  TITLE     A novel, functional and replicable risk gene region for alcohol
            dependence identified by genome-wide association study
  JOURNAL   PLoS One 6 (11), e26726 (2011)
   PUBMED   22096494
  REMARK    GeneRIF: Data conclude that the PHF3-PTP4A1 region appears to
            harbor a causal locus for alcohol dependence, and proteins encoded
            by PHF3 and/or PTP4A1 might play a functional role in the disorder.
REFERENCE   5  (bases 1 to 18797)
  AUTHORS   Beausoleil,S.A., Villen,J., Gerber,S.A., Rush,J. and Gygi,S.P.
  TITLE     A probability-based approach for high-throughput protein
            phosphorylation analysis and site localization
  JOURNAL   Nat Biotechnol 24 (10), 1285-1292 (2006)
   PUBMED   16964243
REFERENCE   6  (bases 1 to 18797)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   7  (bases 1 to 18797)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
REFERENCE   8  (bases 1 to 18797)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   9  (bases 1 to 18797)
  AUTHORS   Struss,A.K., Romeike,B.F., Munnia,A., Nastainczyk,W., Steudel,W.I.,
            Konig,J., Ohgaki,H., Feiden,W., Fischer,U. and Meese,E.
  TITLE     PHF3-specific antibody responses in over 60% of patients with
            glioblastoma multiforme
  JOURNAL   Oncogene 20 (31), 4107-4114 (2001)
   PUBMED   11464277
REFERENCE   10 (bases 1 to 18797)
  AUTHORS   Fischer,U., Struss,A.K., Hemmer,D., Michel,A., Henn,W.,
            Steudel,W.I. and Meese,E.
  TITLE     PHF3 expression is frequently reduced in glioma
  JOURNAL   Cytogenet Cell Genet 94 (3-4), 131-136 (2001)
   PUBMED   11856869
  REMARK    GeneRIF: novel member of a large class of regulatory proteins
            containing a LAP motif, and loss of its expression in glioblastoma
            may contribute to glioma development
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL513043.7 and AL354719.13.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Aug 27, 2019 this sequence version replaced NM_001370348.1.
            
            Summary: This gene encodes a member of a PHD finger-containing gene
            family. This gene may function as a transcription factor and may be
            involved in glioblastomas development. Alternative splicing results
            in multiple transcript variants. [provided by RefSeq, Mar 2014].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.77328.1,
                                           SRR18074968.521585.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000262043.8/ ENSP00000262043.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-349               AL513043.7         35195-35543
            350-618             AL354719.13        4939-5207
            619-780             AL354719.13        38412-38573
            781-2563            AL354719.13        42541-44323
            2564-2870           AL354719.13        50149-50455
            2871-3054           AL354719.13        52993-53176
            3055-3199           AL354719.13        56635-56779
            3200-3356           AL354719.13        56861-57017
            3357-3473           AL354719.13        58762-58878
            3474-3605           AL354719.13        60920-61051
            3606-3741           AL354719.13        61948-62083
            3742-3937           AL354719.13        64441-64636
            3938-4085           AL354719.13        65141-65288
            4086-4175           AL354719.13        67563-67652
            4176-4371           AL354719.13        69579-69774
            4372-18797          AL354719.13        69998-84423
FEATURES             Location/Qualifiers
     source          1..18797
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q12"
     gene            1..18797
                     /gene="PHF3"
                     /note="PHD finger protein 3"
                     /db_xref="GeneID:23469"
                     /db_xref="HGNC:HGNC:8921"
                     /db_xref="MIM:607789"
     exon            1..349
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            350..618
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     CDS             375..6494
                     /gene="PHF3"
                     /note="isoform 1 is encoded by transcript variant 4"
                     /codon_start=1
                     /product="PHD finger protein 3 isoform 1"
                     /protein_id="NP_001357277.1"
                     /db_xref="CCDS:CCDS4966.1"
                     /db_xref="GeneID:23469"
                     /db_xref="HGNC:HGNC:8921"
                     /db_xref="MIM:607789"
                     /translation="MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDS
                     LKNMLSDKDPMLGSASNQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTI
                     DEEELILPNRNLRDKVEENSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKK
                     ASGKTVSTAKAGVKQPERSQVKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSS
                     HSSVSSCLEMKDEDGLDSKHKCNNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMEC
                     KAKPVGSPLFKFSDKEEHEQNDSISGKTGETVVEEMIATRKVEQDSKETVKLSHEDDH
                     ILEDAGSSDISSDAACTNPNKTENSLVGLPSCVDEVTECNLELKDTMGIADKTENTLE
                     RNKIEPLGYCEDAESNRQLESTEFNKSNLEVVDTSTFGPESNILENAICDVPDQNSKQ
                     LNAIESTKIESHETANLQDDRNSQSSSVSYLESKSVKSKHTKPVIHSKQNMTTDAPKK
                     IVAAKYEVIHSKTKVNVKSVKRNTDVPESQQNFHRPVKVRKKQIDKEPKIQSCNSGVK
                     SVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKSHAHPGCLKEPHHPAQTGHVSHSSQ
                     KQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDKLKLKKPEKNLQPRQRRSSKSFS
                     LDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQCGFCKKPHGNRFMVGCGRCDD
                     WFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEILDPDTLENQATVEFHSGDK
                     TMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNSSDCRDNEIKKWQLAPL
                     RKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVH
                     PAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRD
                     TDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRE
                     NRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKP
                     EGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVARK
                     HSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVESTFLAR
                     LNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIK
                     ASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD
                     KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPP
                     DKKSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEP
                     PKPLRFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVK
                     EIPFLNEQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISA
                     GSLTSLSLRGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQT
                     SNSSPCRSNVGKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESK
                     DGDSCRNGEKHMLPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVE
                     NIQTSQAEQAKPLQEDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTS
                     RSTSPRTSTNFSPMRPQQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPP
                     PGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDP
                     WGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRD
                     RKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHR
                     EGEKDRDRYHKDRDHTDRTKSKR"
     exon            619..780
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            781..2563
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            2564..2870
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..3054
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            3055..3199
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            3200..3356
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            3357..3473
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            3474..3605
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            3606..3741
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            3742..3937
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            3938..4085
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            4086..4175
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            4176..4371
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     exon            4372..18797
                     /gene="PHF3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6766..6771
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: AATAAA"
     polyA_site      6786
                     /gene="PHF3"
                     /note="major polyA site"
     regulatory      7220..7225
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: GATAAA"
     polyA_site      7240
                     /gene="PHF3"
                     /note="major polyA site"
     regulatory      7268..7273
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: AGTAAA"
     polyA_site      7297
                     /gene="PHF3"
     regulatory      8072..8077
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: AATAAA"
     polyA_site      8092
                     /gene="PHF3"
     regulatory      13467..13472
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: AATACA"
     polyA_site      13496
                     /gene="PHF3"
     regulatory      18137..18142
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: TATAAA"
     polyA_site      18156
                     /gene="PHF3"
     regulatory      18245..18250
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: AATATA"
     polyA_site      18266
                     /gene="PHF3"
     regulatory      18778..18783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PHF3"
                     /note="hexamer: ATTAAA"
     polyA_site      18797
                     /gene="PHF3"
ORIGIN      
        1 agtggggtca cgtgacacgg cccctctcca gctcccgcgc cgccgccgca cgccgatggc
       61 tgcggggtct cgcgccgtcg caccgtcccc acgcggcaag cgaccttcgg gctcagggcg
      121 gcggcggctg caacgaggat taggagggcg gcgcggaagc caagaatagt gtcgtcagca
      181 gcagccattt ggtcccagga ggaaaagagg ctgtggcagc gacgccgacg tcctgcgcgt
      241 accccctctc cgcggcaccc accgggcccc ctcctcctcc tcttcggcgg cggcagcgtc
      301 caccatcttc ctcttgctgc cagtggtagc gctcgtctgg cggagctggg gctgaaagac
      361 acacagaagt cttcatggat atagttgata catttaatca tttaattcct actgaacact
      421 tagatgatgc cctatttcta ggatccaacc tggagaatga agtctgtgag gattttagtg
      481 caagtcaaaa tgtcttagag gactcgctga agaacatgct cagcgataag gatcctatgc
      541 taggatctgc aagtaaccag ttctgtttgc ctgttttgga tagcaatgat cccaatttcc
      601 agatgccttg ttcaacagtt gttggtcttg acgatattat ggatgaagga gttgttaaag
      661 aaagtggcaa tgataccatt gatgaagaag aactgatttt acctaacagg aacttaaggg
      721 acaaggtaga agaaaattca gtgagatctc caagaaaatc acctcgttta atggcacaag
      781 aacaagtaag aagtttgcga cagagcacta ttgccaagcg ttcaaatgca gcaccattaa
      841 gtaacacaaa aaaagcatct gggaagactg tatctactgc taaagcagga gtgaaacaac
      901 cagaaaggag tcaggttaaa gaagaagtat gtatgtcact gaaacctgag taccataagg
      961 agaatagaag gtgcagccga aatagcggac aaattgaagt ggtacctgaa gtatcagtgt
     1021 cttcaagtca ttcttcagtg tcatcttgtc ttgaaatgaa ggatgaagat ggattagatt
     1081 ctaagcataa gtgtaataat ccgggagaaa tagatgtgcc atctcatgaa ttaaattgtt
     1141 cacttctttc agagacttgt gttactattg gagaaaagaa aaatgaagct ttgatggaat
     1201 gtaaagccaa gcctgttggt agtccattgt ttaagttttc agataaagaa gaacatgaac
     1261 aaaatgattc catttcaggt aaaacgggtg agactgttgt tgaagaaatg atagcaacaa
     1321 gaaaagttga acaagattca aaggagacag taaaattatc ccatgaagat gaccatattc
     1381 ttgaggacgc tggatcttct gatatttcta gtgatgctgc ttgtacaaat ccaaataaga
     1441 cagaaaacag ccttgtaggt ttgcctagtt gtgtagatga agtgactgaa tgtaatttgg
     1501 aattgaagga taccatgggt attgctgata aaactgagaa cacccttgaa agaaataaaa
     1561 ttgaaccgtt gggttattgt gaagatgcgg agtctaatag gcagttggag agcactgagt
     1621 ttaataaatc aaacttagag gtggttgata ctagtacttt tggaccggaa agtaatatct
     1681 tggaaaatgc tatttgtgat gtgcctgacc aaaattcaaa acagttgaat gctatagaaa
     1741 gtactaaaat agagtcccat gaaacagcaa accttcagga tgacagaaac agccagtcaa
     1801 gtagcgtttc ttacttagag tcaaaaagtg taaaatccaa acatacaaaa cctgtaattc
     1861 attctaagca aaacatgacc acagatgctc cgaagaaaat tgttgcagca aagtatgaag
     1921 taatacatag caaaactaaa gttaatgtca aaagtgtgaa acgaaatact gatgtaccag
     1981 aatctcagca aaattttcat aggccagtca aagtcagaaa aaaacaaatt gataaggagc
     2041 caaagattca gagttgcaat tctggggtta aatctgtgaa aaaccaagct cattctgtac
     2101 tgaaaaaaac attacaggat caaactttag tacaaatttt caagccctta actcattctt
     2161 tgagtgataa gtcacacgct catcctggtt gcttgaaaga acctcatcat cctgcacaaa
     2221 ctggacatgt atcacattct agccagaaac agtgtcataa gcctcagcaa caggccccag
     2281 caatgaaaac caatagtcac gtgaaggaag agcttgaaca cccaggcgtt gagcatttta
     2341 aggaagagga taaactgaaa ctgaaaaaac ctgagaagaa cctacaaccc cgccaaagaa
     2401 gaagcagcaa aagtttttct ttagatgagc caccattgtt cattccagat aacatagcta
     2461 ccataagaag agaaggctct gatcatagct cctcatttga aagcaaatat atgtggactc
     2521 ccagcaagca gtgtgggttt tgcaaaaaac cacatggcaa caggtttatg gttggctgtg
     2581 ggagatgtga tgactggttt catggtgatt gtgttgggtt aagtctttct caagcacagc
     2641 agatgggcga ggaagacaaa gaatatgtct gtgtaaaatg ttgtgctgaa gaagacaaaa
     2701 agactgaaat actagatcca gatactttgg aaaaccaagc tacagttgaa ttccatagtg
     2761 gagataaaac aatggagtgt gaaaagcttg gattatcaaa acacacaaca aatgatagaa
     2821 ccaaatatat agatgataca gtgaagcaca aggtcaaaat tttaaaacgg gagtctggtg
     2881 aaggcagaaa ttcatcagac tgtagagata atgaaattaa aaaatggcag ctagctcctc
     2941 ttcgtaagat gggacaacca gttttacctc ggagatcctc agaagaaaaa agtgaaaaaa
     3001 taccgaaaga gtctacaact gttacttgca caggagaaaa agcttcaaaa ccaggtactc
     3061 atgagaagca agagatgaaa aagaagaaag ttgaaaaagg agtgcttaat gtacatcctg
     3121 ctgcttctgc ttccaagcct tctgcagatc agatcaggca aagtgtcaga cattctctca
     3181 aagacattct tatgaagaga cttacagact caaatttgaa ggtaccagag gaaaaggcag
     3241 caaaagttgc cacaaaaatt gagaaagagc ttttctcttt ttttcgggac acagatgcta
     3301 aatataagaa caaatataga agtttgatgt ttaatttgaa agatcctaaa aacaatatat
     3361 tatttaaaaa agtactgaaa ggagaagtaa ctcctgatca tcttatcaga atgagtccag
     3421 aagaactagc ttctaaagag ttagctgctt ggagacgaag agaaaacaga cataccatag
     3481 aaatgattga gaaagagcag agagaagtgg aacgacggcc aatcaccaaa ataactcata
     3541 aaggtgaaat agaaattgag agtgatgccc caatgaaaga acaggaagca gccatggaga
     3601 ttcaggaacc agccgccaat aagtcattgg agaagccaga aggatctgaa aaacaaaaag
     3661 aggaggttga ctctatgtct aaagatacca ctagtcaaca cagacagcat ctttttgatc
     3721 tcaactgcaa aatctgcata ggtcgaatgg caccacctgt agatgatctt tctccaaaaa
     3781 aagtaaaagt tgttgtagga gtagctcgca aacattcaga caatgaagca gaaagtatag
     3841 cagatgcatt atcttcaacc tcaaatattt tggcttctga attctttgag gaggagaaac
     3901 aggagtctcc aaagtcaacg ttctctcctg ctccacgtcc agagatgcct ggaactgttg
     3961 aagttgagtc tacctttctg gctcgattga acttcatctg gaaaggtttt atcaacatgc
     4021 cttctgtggc aaaatttgtt accaaagcct atccagtatc tggctcccca gaatacctga
     4081 cagaggacct accagatagt attcaagtag gtggcaggat atcacctcag acagtttggg
     4141 attatgtgga aaaaataaaa gcatcaggaa ccaaggaaat ttgtgtggtt cgcttcacac
     4201 cagtaactga agaagatcaa atttcttata ctttgctctt tgcatacttc agtagcagaa
     4261 agcgctatgg agtagctgct aacaacatga agcaggttaa agatatgtac cttattcctt
     4321 tgggtgccac agataaaatt ccacaccctc ttgtgccttt tgatggacct gggcttgaac
     4381 tgcatagacc taatctattg ttgggcttaa ttattcgtca gaaactgaag cgacagcaca
     4441 gtgcctgtgc tagtactagt catatagctg agactcctga aagtgcacca ccaatagcat
     4501 tgccacctga taaaaaaagt aaaatagaag tttctacaga agaagcacca gaggaagaaa
     4561 atgacttttt taattctttt acaactgtat tacacaagca gagaaataaa cctcagcaga
     4621 atcttcagga agaccttcca acagcagttg aacctttaat ggaagtcacc aaacaggagc
     4681 caccaaaacc tttaagattt cttcctggcg tgttgattgg ctgggagaat caacctacta
     4741 ctctggaatt agcaaataaa cctcttcctg tggatgatat acttcaaagc cttttgggca
     4801 ccactggtca agtatatgac caggcccagt cagtgatgga acaaaacact gttaaagaaa
     4861 ttccattttt aaatgagcag accaactcaa aaatagagaa aacagataat gtggaagtaa
     4921 ctgatggtga aaacaaggag ataaaagtta aagtagataa tatttcagaa tctacagata
     4981 agtcagcaga aatagaaaca tcagtagtag ggtcctcttc catttctgca gggtctttga
     5041 cgagtcttag tctcagaggt aagccaccag atgtttctac agaagcattt ttaacaaatt
     5101 tatcaattca gtcaaaacaa gaggaaactg tggagagtaa agagaaaaca ttaaaaagac
     5161 agcttcagga agatcaagag aataatttgc aagataacca gacttcaaat agttctccat
     5221 gcagatctaa tgtaggaaaa ggaaacatag atggtaatgt gagctgtagt gaaaaccttg
     5281 ttgctaatac agcgaggtct ccacagttta tcaacctgaa aagggatcct aggcaagcag
     5341 caggacgaag tcagcctgta actacttcag aaagcaaaga tggagatagt tgccggaatg
     5401 gagaaaaaca catgctgcct ggcctgtcac acaacaagga gcacttaaca gaacaaatca
     5461 atgtagagga aaagttgtgt tctgcagaga aaaactcgtg tgttcagcag agtgacaatt
     5521 taaaagttgc acaaaactca ccatcagtag aaaacataca gacttctcaa gcagaacaag
     5581 caaaaccctt acaggaggat attttaatgc aaaatattga aactgtgcac ccatttcgaa
     5641 gaggatcagc agtagcgaca tctcattttg aagttggaaa cacatgtcca tcagaatttc
     5701 cttctaaaag catcaccttt acttccagaa gcaccagccc cagaacaagt acaaactttt
     5761 cacccatgag gccacagcag cccaaccttc agcatctcaa gtctagccca cctggatttc
     5821 catttccagg gcctcctaat tttcccccac aaagcatgtt tggatttcca ccacatttgc
     5881 cacctccatt acttccccct ccaggctttg gctttgctca aaatcccatg gttccctggc
     5941 cacctgttgt tcatctccca ggtcagccac agcgtatgat gggtcctctc tcacaagcat
     6001 caaggtatat aggcccgcag aatttttacc aggttaaaga cattcggagg ccagaaaggc
     6061 gccatagtga cccttggggt aggcaagacc aacagcaact ggataggcca tttaataggg
     6121 gtaaagggga ccgccagaga ttttatagtg attcacacca tttgaaaaga gagcgacatg
     6181 aaaaggaatg ggagcaagaa tctgaaaggc atagacgcag agacagaagc caagacaagg
     6241 acagagacag aaaaagcagg gaggaagggc acaaagataa agagagggca cggttatcac
     6301 atggtgatcg aggaacagat ggaaaagcaa gcagagatag taggaatgta gacaagaagc
     6361 cagataaacc taaaagtgaa gactatgaga aggacaaaga acgagagaaa agtaaacaca
     6421 gagaaggaga aaaggacagg gataggtacc acaaagatag ggaccacact gacagaacta
     6481 aaagcaaaag gtaaaatttg caggctgctt caggattaca tttaaataac tgttaaaatg
     6541 ttgtatcttg taaacaaaag aaagattgcc tgctaggatt gtgccatctt taaaattttt
     6601 actattggtc atttgcagaa cagtaaattc tgtgtgttgg tacagagtgc tctgtaccag
     6661 tgctcatcat cccttcttca taccaacggt ccctagttat aggaatttaa tatttttaaa
     6721 agttttacat tgctgtatat tcaaagattt gttttattaa tatgcaataa aggcttagaa
     6781 attttagttt tattccttaa ttggtaaata tggttaacta tggaatatat ttacttcctc
     6841 tagtgaatgt cctttatata atgactaatt tgggagtaat gtgtgctctg taagtttgtt
     6901 ttaaattgca ctgtttttaa agaaactgta gaggagcaac aaaaatccaa gcaacttcat
     6961 aatcagatta tgctaatcat ttagttgagc agtttttgac caagaatcag aagcccaagg
     7021 ggtacattta ttgctttaat ctgcactcat tgaagtcatt tattaccata tactacagct
     7081 ttgtggtagg ccattatttt cattttcatt tttggctctt cagaaacttg aatacttaag
     7141 cttgtacatg atcttgtgtt ttgctatcct ttttactgta aaatgtaaat attttaaggg
     7201 atattttgat tctaaatatg ataaaataat ttctcaccta ttttgtgtgt gtgacttgaa
     7261 attcagtagt aaaagaattt cttctttaaa gctttaatta ccttcagaca ttgatttttt
     7321 gttactcagc caagaacata tagaaatagc tatctatgtc aggcattaga tgaggggaaa
     7381 aacaattttt ttaaaatctt aaattgtagg ctgagatgaa ttgtgtagtt ctaaagaggc
     7441 tagaatttag aactacctgt gaaacactgt gcagctatag cccactttat aggtaagttt
     7501 ctgaaaactt ttacaccatc gcaatttggt actctgactc actaatcatt aaaattaaag
     7561 accgcagaac ttgaagagaa atatgttttg aatcctttta taaaatgtgc gatttagcct
     7621 aattcgtaaa gtaactgtac agtttcatat gccagtttta cttgaaaaaa aaatatgaaa
     7681 actattgtta attcaaatct aaatttattt aaaccctaaa acacatggtt ttgatggctg
     7741 taatttaaag taagagctat caaatgatgc tgacaaaaga aaaaccttcc aaaatacaaa
     7801 agaaagagaa ctctattatt tacttacctg tattaatgaa gaaaaatata aataattcca
     7861 caaaattgat tgttttccta aagagcttaa agattagagt taaaaattgg ttttgaaaca
     7921 gaattatcct tgttattttt gctggagaga agggaggaaa ttcagaacca aacattctat
     7981 ttaatttgca atgacttgca gtactttttt ccctatcctt atcctgtgaa acttactatc
     8041 ataaggttct aaaacagaga acttgtgttt aaataaagcc cgtttaactt tggtccactt
     8101 ttcttttgga aattaacttg ttagaaaaca aagttagttc ccaaacaaaa caaaatctaa
     8161 gttataattt gcaccattac aaagaaattg ctgtcagggt tttacacatt ttaaaaacat
     8221 ttcaatttca aatgtgtata tcgtcaataa atctaccttt actgatatat ctggttgagg
     8281 gaatatcaga ctccagattt cttttgcaag atgaaagtaa aaacgagtgg gttaatgaat
     8341 gaaaacaagc ttttaggtca gtttttgatc acctcttcgc taatagtttt ttctacatat
     8401 ctaaaattct ttaatcagtt ctgatcgaat cttgatacat gtttttaaaa taggcaaggc
     8461 ccatatagct ttctattagg gatgagcatc tccaggggtt agaggcagat cttgtaaccg
     8521 ctgattgact gaaacatttt atggagaata gggaaggtat ggtcatatta gctatttgag
     8581 gttttccttt tgaggaaaaa aagggaaaat gagcagattt ttcaatgagt agtagatcca
     8641 aagccattct cagtcccagg tacaaccagc cttacacaaa ctagtgaatt acatgaattt
     8701 catctttcag tttctcctgt tttaagaaaa aacctgctct ttaaaaaaag ttttacactt
     8761 aaaaaaactt agaatcatct taagacagtg aatgcatacc tctattaggt aaaagtacca
     8821 gggcatctca gtacctgtaa agttcacccc atgtaatctt tgtggcaatc agaaagcctc
     8881 cttgagccct ctgtaaggca tccctggttt tgagcactta gtataaacat tggtcaactc
     8941 aaaggtgaag gcttagagct gaggaaactg gaacttagag aagttgggaa acttggccag
     9001 gttaccctgc tgttgtcaga gcaggaatcc tacctagctc agttcttttc tctaaagtcc
     9061 atgtgcttag caattgtgct ctgagaattg agaatgagaa aaagaagcaa aagcctgatg
     9121 atcatatata cctttcatag ccctctttct ttgcgttcca ctgaactgtc tgaaaccctt
     9181 cactgagcaa cccaactgtt cagtgtgagt cagaagacac aaccaaaaac ctgtaagttc
     9241 ttttgtacgg atttgcaaaa tttatattaa tcacaaatcc taattctcta ttcctgtttt
     9301 ctattgctgt tgtgatgaat tactacaagt gtagtggctt aaaaccacac aaatttatga
     9361 tcttacggtt ctgtggatca gaagtctgtg cagatctcac tgggtaagat caaggtgtca
     9421 gcaagatgca ttcattttct ggagactttc agggagattc cttttttttt gcgccttggt
     9481 ttctagcttc tagagggcac ccaatttcct tggctcatga tcccttcctc catatttgaa
     9541 gccagcagtg tgggacccag tctttctcta gtatctctga ccttcccttc tgattccctc
     9601 ttctactaca aaggaccctt gtgattacat tgaccccacc cagataatcc agggtaatgt
     9661 tcctattttc aggtcagctg atgagcaact taaattccat ctgtgacctt aattccctat
     9721 tcccatgtaa cctaacatat ttacaggtgt tccaaggatt ggggtgtaga catcttttgg
     9781 gggattatca tctaccaaca gcccttgact tactaattgt agtttattgt gggtgaatta
     9841 atctgaaatc tttatagaat agctaaggct atagtaaata catgtgaaaa atttaagaac
     9901 aataacacca gcaatagaga agaaaatgga gtgaaaagtg aagccactcc atgttaacgt
     9961 gtgtgttaac ataaaactac ccgtcaacag gtaactttac tctgttgttc ctaagttttt
    10021 aatagtagct gtgtttttaa agtttatgaa ccaaacttaa atgcattatg agagcttgat
    10081 aatgaaccag atcttagtaa aacagtattt taacatttgg atatactagt tgtactatgc
    10141 ttatctcaga tccctgtaac actggtcagg ctacaactta ctaatgacta caaagaacta
    10201 tatacacaat caggtttatt tctgtctctt aaagcaaatt gcaaataaaa ttggttactg
    10261 cttttaaaaa ggtgccaaac accctaattc tttgatttct gtttcacaat tatagtaata
    10321 tgtagagcaa aaaagtagtg agttgaaaac agatcagtag caagaagtcc tttgaaaact
    10381 tgagttcacc atgtcaagtt tcatcttata gatagatgca gagcagagtc attgagggaa
    10441 atagcctaag cactcaaagg gcagtgaatc caatataact ctaaatatcc ccaaaatact
    10501 ttttctatga aataattcag tgtgtgcatg tccatgtgtg tatatataca tatatgttag
    10561 cccaagctgt cttttaaaac tccttatttt aagataattt tgtcctcaaa gtaatgattt
    10621 ttttcaggaa cttattattt ataaggagac caaaaaggta aatattactg caccttattt
    10681 ttaaaaaatg ttccgtttac attcaacact ttgagaaacc tcatacattt atagtaaaat
    10741 cttaaaggtc tttctgtagc caatcatttt tatttcgtac tggaaaagca tttcacatag
    10801 gaaatcgtca acaccattat caccaggata gcaaaaatag gaagcgggaa tagtgttgat
    10861 ttgttacatg aactttccag gattttaagg tgaaaaatat attttcaagt cattttgatt
    10921 tataggagaa aaggcagcag ttttcagttc ttaaatattg tctgcctatt ctgcaagcac
    10981 aattttctgc gtttggaatt caatgatgag caaaatggga aagttccaat tttgtggaga
    11041 ttacaggtag aaaagttata aaatctgaac gtaaaattgc aactgtgaaa agctttaagg
    11101 cagcaattct caaacttttg ttttcaagac cccttacact cttaaaaatt gagaatgtca
    11161 aagcttttgt ttatatggct tatatcatta tttagcatac tagaaaatca aatgataaac
    11221 gttaaaaata tttgttaatg ataatctcat ctgttaatgt aacatttata taaaagttaa
    11281 cttccaaact aatttagtaa gaagagtgtc attgtcttga tttttgcata tttccaattt
    11341 ctgacttagg gctggattct cttacctgcc ctgcattcag tgttttgtag tatgtcattt
    11401 tatttgaaat atatgaagaa aatctggcta tatgtgcatt tgtttttggg aaagggagga
    11461 ctctggattc cttgaaaaga tcgcaggggt tcttggacca tagtttggga agtgctattt
    11521 taaagaaaag gcacacttta ttatgagaga acacatggcc gaatatgatg ggagtgtggt
    11581 tcaggcagtt tcttcttttg taagctttca taaaacagcc ttctttttat acataaagta
    11641 tgttttctga aaggttagat ttgattacca gctgccaaaa ggaatttctt cagagcattt
    11701 atccttatga tctgagtatc tccaaagtta aatgcaatag tatggagcaa taccagttta
    11761 ggtcacagtt tttcagcaaa atttgatgga gttgttttaa gtggtttccg ttaaaaaaac
    11821 aaacctttga atcaatgtgt aaacattctg caattctacc ttatattcta ccctcacact
    11881 tcctagtatt aatatgaact gtatgtttgg aaacatttgt gccctgtcaa atggtgttga
    11941 cattcttaac tctggtcgta ggtcctttta ggaatgtctg tagccttttg attggaatgg
    12001 agtggctaaa ataagacaaa aatctctaat agtttttgaa tgataaatta ctacctcgtt
    12061 actttgtata gactggaatc tgcacagaaa tgtgtattca tcagccctta ttttttgtaa
    12121 atcttttctc taattacttg atgattaatt tcatattttt ccttttgaac attacatgct
    12181 gcttattact aagatttttt tctccagatg acctattcta cctgttagtt caccaagtca
    12241 gtcatatgtt gccggttgcc aagtggcaaa attatcacag atatcaaact cagaaaatgt
    12301 caggtaacaa cagcagtaac tgctttccaa cctgcagtgg tggactggga gtgggaagtg
    12361 aaagttctgt tcacaattgt atcagtaact gttttgggaa aaataatatt ttttcaagtt
    12421 atgctatcaa cagtactaaa ttgttaggat agtaattttc catggcattg tttagaacct
    12481 attttatgcc caattttgag atctgtatag acttgaaagc agttaaacac aaattaaggt
    12541 taatttttta atttgatcag ttaatatgag tacatggttt taaaaagtca aatagttcta
    12601 caaggttcat aagcaaaaag caacaggctt ctgcactact cttctctcca gaggcaacca
    12661 tttttaattc ttttagatat ttaggatatt tgccttcatg tttgtgatat gcatatgcta
    12721 tgttttaagt tgcacatatt gtaatatcta ttgatgtctt actataaaag ataaggattt
    12781 agctcttacc agcctgttct cctctcctct caccttctct ttctacattc atgcaataat
    12841 ttttggttta aatctatgtt caagttttac attgttgaat catataaata agttgtagct
    12901 aagccatgta atacaatatg gttacattgc tttgtataat ttttattttt cctttgatta
    12961 ataacttgat ttttttctta tttgtaccta tccctaattc attcccaact gaattttaaa
    13021 cattttaaag ttcagcttac acattgattt ttaaaattgt gtttacacgt tgattttaaa
    13081 atgtaagcat tagggatagg taaaaagtga ataagcaaag tgaataagca cattctgtga
    13141 ataagcactg aactaatgga gttaaaacat gaatcaaaat atatacagat aaattagatg
    13201 taggaaaaac aatcagaacc ttcagtgaca ttttacaatc ttatcaaaaa gatatgttag
    13261 catttagact atttcaggta atatagtaaa cagttgattc cccgtaagca atgtatcaaa
    13321 gaaataacta tcaaaataac tgcatttatg tatagtgtgt actaaaatct ctagtgttaa
    13381 cttatgtaac ctcattttgt tcatctccat cataaacatt gtatccttct aatttaatta
    13441 gttcaatgtt ttttggttcc tgaaaaaata caacatcttt aattttgcca acaaaattgg
    13501 ttttaaaaat ctcttgagta acgatattta cctttctacc atattcaaag ccccctagat
    13561 aacaaatgcc atcatagttt agagccacaa agtttttatg tggatcaata tcctcggaaa
    13621 gaattagact gttatttatg taggccttga taagagtctg attttgaatt acaactacat
    13681 ggtgccattt attacaacag aatgtgccat tgttatagct cataggcaca gagattcttt
    13741 ctcccaagtt aactgctatt ttcaaggtct gattatggag accaattgcc agaaaatcat
    13801 tttcttcatt ttgagctatt cccatccata caattagacc ttctgtttta gtggtactga
    13861 aatttaagga tatagtagtg aactggaggt ttctcattct ataatttgga tcaatgtatt
    13921 taatgtaaga attacccata aattttgcag ttgaaaatga agttttgttt tcacaatacc
    13981 ttcccaccca acccaaagta cacaggcaac tgtaagaaaa tgattggtca ggtatacata
    14041 aagattggtg gaggcaaaga ttattcaaac aggacacaga ctggttacat gtatttccag
    14101 cccaatctgg caaacatctg caagaaaaag ttgtgccatt tactgtacat tcacctccat
    14161 ttctgcatgt gttgtaccca caggctgtcc catcacagtc acctacattt gagccacctt
    14221 ttgctccaaa ttcagttaat tgtaattctt gattatttat gataacttgt cggatacagc
    14281 cttgaaaacc tacaggttca ttttctattg ccatgggatt tacaagattt aaagaagata
    14341 ctcctccaat atagaagtct gtatttgtgt ccagagaact cattttagtg gaggcctttt
    14401 ctgttacatt tatcccatct agatccaggt agccttctgc accaactctt cctgctttta
    14461 ttatatgcca agtacttccg tttatagtta ctttttggag agtttctaga atgatagttc
    14521 tgtcgccaag gttgtagcga agttgaacgg aactatttac taaagagatg cataaaaaat
    14581 cacctgcaag aaagcaaaca gtaagtttga ttagcaacag taaaagtttc cattgaaaac
    14641 ttttgctgtt tctggccaag ttggataagt tttagttatg gggaaaaaag taacagatct
    14701 tgagcacaat tgtgttagtt ttgtttccac tcacagagca aaatgcatat atcctgtatt
    14761 ctttcatttt gttcagcaat tggctacata aattttctct agttgtggac agttctcatt
    14821 gaatgaatat attgtggtag taagttaaag tgaggttttt cttcaaatga aagcctgttc
    14881 cttatgatac catttaatgg cattcactat tgtcaggcta ggtacctata aattctctgc
    14941 acattcctgg ctcctttcct gtctctccaa ccttacctgg aatgttctct ttccccatcc
    15001 ttacactctc tttacttcaa caacactgac tttgttaatt aaggatttca ttcgcctgtt
    15061 ttctaggaac actccgccac cccattccac ctcaactaga taactcctac ctgtccttca
    15121 ggtttcagat caagtgtcac ttcctcagag aagttttcct tgatttccca gagctggtca
    15181 ggaatttttt tctgtcagtg ccttaatatc actaggtttc cctccattac agtatatctc
    15241 attttataat tatatagtcg tgtgaagaaa taggaacaaa taccatccag catctgaagt
    15301 tgcaatgagg cattcagaag aaaagtaaag gcaattctgc aagcttggaa aaagcatgtt
    15361 cttcactgta agattgcttg aagaggatag caaaatgact tattaataat gaaccacgca
    15421 gaagtctcca cgaaacattt tcttctccct ctgaaatttc ccaacctttt tcttttctca
    15481 tccagggata ttcggcatta tgctacacta cttcttcctc cctccagagt gcctatttcc
    15541 acacctccct cctgcaaatg gtgttctttc cttctattct ccattgtggt ctataccaag
    15601 ccattctaga ctggttggaa tgtttggcag ctctatagtt cttcacctat caaactacgt
    15661 tctctagctt tattttcctc atagggaatt tttagtgagt atactatgtc gttacatatg
    15721 tgatatttgg ttaacagctg ctttatccac taggttgtaa gctttatgag aacagggtct
    15781 gtgtttggtt tggtccaaca gttgattccc agcacccaaa acggtatctg gcccataaat
    15841 agatgctaaa taattattaa ataaagaaat acgtttgtag ggttgtgggt tgagatgact
    15901 cagaatattt ctcaaataat agttttagct tgaaagcaaa aacttttttc ctataatgac
    15961 atgaaaattg ttttaaaaat tcataacaaa gaaactcagt ttatttgcat aatttctaac
    16021 atgtatagca tttttaacta taaggaaaga gaagcaacat tataaacttt cagattagga
    16081 aagaaaaaat atacattggg ttataccacc aaaaactgga acaagtaaac ataattgata
    16141 attaagttca aaaaatttat agcaacctaa atatactttg tggcctgcaa gtgaacacaa
    16201 accagttatc ttttgcaaga ttatggagga agcttttctt gctccttgtg ttgtagagtg
    16261 ttcctgtagt aaacaatttt atagtgaaga gctacattag aataaaaaat atctaagaaa
    16321 tgattaggaa agctgaagct gtgatctata ctatcactgg tcatgttgcc aaccagaaga
    16381 aagagcaagg atagcttctg cgaagaaagg attattttaa ctcagctagt atgttcttac
    16441 gaaaaattga caaaaagttt tctttctgtg gctatggaag ctaaaagctg tattagctta
    16501 aaaaatcata gacttttaaa tttcattgcg ttaggatatg atgctctagt tatgggtcat
    16561 aagtacacat tggcattatt attattatta ttattattat tattattatt attattatta
    16621 ttttgagacc agagtcctgc tctgtccccc aagctggagt gcaatggtgc aatctcggct
    16681 cactgcaacc tccatctccc gggctgcctc agtttcccga gtatctggga ctacaggcac
    16741 tggccatcac ggccggctaa tttttgtatt ttgggtagag cgaggtttta ccatgttggc
    16801 caggctggtc ttgacctcct gacttcaggt gatccgccca cctcggcctc ccaaagtggt
    16861 gggattacag gcatatgcca ctgcacctgg ccttggattc gcattagagt aagaaaatgt
    16921 aatgaacagt ccttacaaga aacagagctc aaataggata aagatcataa atgaattcac
    16981 tttggctatt taatgcccac tcaaccatgg ctgaggcttc tcccaccttt gttctgctat
    17041 tgtttctacc tcatcatctg ctatcccacc gtgctttatt atagataaga gaaaccttgt
    17101 aggacctaat atttgtgaag agactacaga atcagcatat caggggaatt gtatatacat
    17161 ttttttctgt agaaaaggaa agcaatggta atttaaactt atttatatat ttttaatata
    17221 gtttaattat ttgagtatgt tttaacttca cattgcaatg actaggcctt tttatacacg
    17281 ttgggaggat tataactata tcagatgaat tcaggctttg attaatttgt gcttaacaaa
    17341 atgttgataa tttttatata tcaaaaatct tttaaaggtg ttaaattttt agcagaaata
    17401 gatgaaaagg gaccagagtc ttatttcttt aaaatatctt tcaaaaatca gagatctgag
    17461 atcatctagt ataattttca agttatcatt ttgttttaaa ttttacacta cttgagagta
    17521 ctcaaattat taacctctaa agagatacag aaaccatgtt aatttagaat ttggttttca
    17581 atatgtgaaa accacattgg ctgcttttat taaaattttt ggattttaac tttgtgtatt
    17641 gtttggttag tttttactaa taggtcctct tagcagagga tcaactatga agacttggtt
    17701 aatgtttaca tcaggcacag ttcttagaga aggtacaaag tacaggactg tcagctgcat
    17761 tttctgcaac cttaaataaa tgagagactt caaataaact tgttatatca cttgattact
    17821 aaaaaataag tttatgcctt tcatctgata attgtttttg gttaatctag gtttaagcat
    17881 gtagaactta tatttttaat atttaaaaat tttcatgatt ttcttatata agtgtcaaat
    17941 gcagcatcaa tcgtgtgaaa ctaatgaatc tctgtaagta gtgtctgatg gcataaaaaa
    18001 ggaaactctt gattgtcttg aactacatgc attgaataac agatgtaaga agatgtgctc
    18061 ttgccctcct atgtgtatta gtgtgtatga gctttatatt tcatatacac aaacaaatat
    18121 gtatcgttgt actgattata aaactgtagt acaatattcc cagccagtca caatcctgaa
    18181 tataccttga ttttctgccc tcttacatag gtcccactta acattaattt tgagttttat
    18241 tagcaatata actgaagctg attgtctttt aatgtctctt gatttataaa tagaaaattt
    18301 atgtttgtat gtggttctcc tatttgacat tttcacaggg agatttaatc atgaatttaa
    18361 aaccaaatat ctcaggagaa caaatttctt ctgagctgta ttttatagct caattgtact
    18421 ttttctcttt gaaattattt tgagggtatt tcagaagtgc attgaggtgg aaccactttg
    18481 gtcgaattcc ctgatattct tatcatttag aagcaagtca agacacttct ataagaacta
    18541 cttagattat gatcattaga gcaccatttt tgctaatgat gtgaaattta gcaaatgtaa
    18601 ttatttctca atatcaaaat tgtttctcat tttctgagag acaagatcaa agaaagtcaa
    18661 atgtaagatt ttaaaaatac ttagcaatag agatgtaact atatgtgcag atgtctttgt
    18721 cagaattttg gagaaatgaa tgaaaatgga tatcaagggt aaagtaaaac ctaaaaaatt
    18781 aaattttaaa acactaa
//
