LOCUS       NM_001102612            1139 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens pyroglutamyl-peptidase I like (PGPEP1L), transcript
            variant 1, mRNA.
ACCESSION   NM_001102612 XM_927974 XM_941169
VERSION     NM_001102612.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC036108.19, BC104743.1, BC104744.1 and AK058162.1.
            
            On Nov 19, 2009 this sequence version replaced NM_001102612.1.
            
            Transcript Variant: This variant (1) represents the allele encoded
            by the GRCh38 reference genome and encodes isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC104743.1, DRR138525.417389.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465413 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                AC036108.19        147161-147254
            95-281              BC104743.1         1-187
            282-308             AC036108.19        151591-151617
            309-724             BC104743.1         215-630
            725-793             BC104744.1         538-606
            794-1089            BC104743.1         700-995
            1090-1139           AK058162.1         1435-1484
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q26.3"
     gene            1..1139
                     /gene="PGPEP1L"
                     /note="pyroglutamyl-peptidase I like"
                     /db_xref="GeneID:145814"
                     /db_xref="HGNC:HGNC:27080"
     exon            1..228
                     /gene="PGPEP1L"
                     /inference="alignment:Splign:2.1.0"
     exon            229..321
                     /gene="PGPEP1L"
                     /inference="alignment:Splign:2.1.0"
     CDS             301..891
                     /gene="PGPEP1L"
                     /EC_number="3.4.19.-"
                     /note="isoform 1 is encoded by transcript variant 1;
                     pyroglutamyl-peptidase 1-like protein"
                     /codon_start=1
                     /product="pyroglutamyl-peptidase 1-like protein isoform 1"
                     /protein_id="NP_001096082.2"
                     /db_xref="CCDS:CCDS53977.1"
                     /db_xref="GeneID:145814"
                     /db_xref="HGNC:HGNC:27080"
                     /translation="MKPRTLVELSKLGLGNETVVQLRTLELPVDYREAKRRVTGIWED
                     HQPQLVVHVGMDTAAKAIILEQSGKNQGYRDADIRSFWPEGGVCLPGSPDVLESGVCM
                     KAVCKRVAVEGVDVIFSRDAGRYVCDYTYYLSLHHGKGCAALIHVPPLSRGLPASLLG
                     RALRVIIQEMLEEVGKPKHRAQFEENSTMVLPAKGN"
     exon            322..444
                     /gene="PGPEP1L"
                     /inference="alignment:Splign:2.1.0"
     exon            445..671
                     /gene="PGPEP1L"
                     /inference="alignment:Splign:2.1.0"
     exon            672..1139
                     /gene="PGPEP1L"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atccttggcc tttcggggcc cagaacgcta cggacgccgg gcggccagga ggggttgggc
       61 tcccgctcca ccccggtccc cggcgagcac gcggccaggc agagaaggtg cccggagctc
      121 agagcgcgca gagcccggcc gctgggccgc tgcctgagcc agggaggcgc agcgcgagct
      181 cccacttcgt cttcatggat tcccagccca gctgcgtggt ggtgactgca tgttttcaag
      241 gttgagccac gtggtagtgt gtccagaatt ggtgggttgt tggtctcact gacttcaaga
      301 atgaagccgc ggactctcgt ggagctctcc aagctgggcc tggggaatga aacagtggtg
      361 cagctgcgga ctctggagct gcctgtagat tacagggagg ctaagcggag ggtcaccgga
      421 atctgggaag atcatcagcc gcaactcgtc gtgcatgtgg gcatggacac cgccgccaag
      481 gcgatcattc tggaacagtc tggcaagaac caaggctacc gggacgccga catccgcagc
      541 ttctggcccg agggcggcgt gtgcctacct ggcagcccag acgtgctgga gtcaggggtc
      601 tgcatgaagg cagtctgcaa gcgcgtagct gtggagggtg tcgacgtgat cttttcccga
      661 gatgcaggca gatacgtctg tgattatacc tattacctgt ctctgcatca tggaaagggc
      721 tgcgcggcac tcatccatgt ccctccacta tcgcgcgggc tcccggccag cctgctggga
      781 agagccttga gagtcatcat ccaggaaatg ctggaagagg tgggaaagcc caagcacaga
      841 gcccagttcg aagaaaactc aaccatggtc cttccagcca aagggaactg accgggggat
      901 tgctcctcta gagaaaattg aatgtttcaa tcctgtatgt agcactcaac tgtgcattga
      961 gaaacttttt caaaaattgc ttgtaagaca aagagggtgg aaaactctga attagcccaa
     1021 caaaatcaca aagggttatt ttattgtcag gagaaagaac actctgaaag gtggacattt
     1081 cacaggggat gaactagctt cagttatggt tttcatgaca ataaaatgaa atccgagtc
//
