LOCUS       NM_014389               5084 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens proline, glutamate and leucine rich protein 1 (PELP1),
            transcript variant 1, mRNA.
ACCESSION   NM_014389
VERSION     NM_014389.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5084)
  AUTHORS   Skibinska,I., Andrusiewicz,M., Jendraszak,M., Zbikowska,A., Zaba,C.
            and Kotwicka,M.
  TITLE     PELP1 and SRC kinase as important molecules in the
            estrogen-mediated pathway in human testis and epididymis
  JOURNAL   Acta Biochim Pol 70 (2), 447-456 (2023)
   PUBMED   37159918
  REMARK    GeneRIF: PELP1 and SRC kinase as important molecules in the
            estrogen-mediated pathway in human testis and epididymis.
REFERENCE   2  (bases 1 to 5084)
  AUTHORS   Skibinska,I., Andrusiewicz,M., Jendraszak,M., Zbikowska,A.,
            Jedrzejczak,P. and Kotwicka,M.
  TITLE     Expression of estrogen receptors, PELP1, and SRC in human
            spermatozoa and their associations with semen quality
  JOURNAL   Hum Cell 36 (2), 554-567 (2023)
   PUBMED   36577884
  REMARK    GeneRIF: Expression of estrogen receptors, PELP1, and SRC in human
            spermatozoa and their associations with semen quality.
REFERENCE   3  (bases 1 to 5084)
  AUTHORS   Gordon,J., Chapus,F.L., Viverette,E.G., Williams,J.G.,
            Deterding,L.J., Krahn,J.M., Borgnia,M.J., Rodriguez,J., Warren,A.J.
            and Stanley,R.E.
  TITLE     Cryo-EM reveals the architecture of the PELP1-WDR18 molecular
            scaffold
  JOURNAL   Nat Commun 13 (1), 6783 (2022)
   PUBMED   36351913
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5084)
  AUTHORS   Wang,X., Yin,W. and Liang,L.
  TITLE     PELP1 is overexpressed in lung cancer and promotes tumor cell
            malignancy and resistance to tyrosine kinase inhibitor drug
  JOURNAL   Pathol Res Pract 237, 154065 (2022)
   PUBMED   35969940
  REMARK    GeneRIF: PELP1 is overexpressed in lung cancer and promotes tumor
            cell malignancy and resistance to tyrosine kinase inhibitor drug.
REFERENCE   5  (bases 1 to 5084)
  AUTHORS   Zhang,D., Dai,J., Pan,Y., Wang,X., Qiao,J., Sasano,H., Zhao,B.,
            McNamara,K.M., Guan,X., Liu,L., Zhang,Y., Chan,M.S.M., Cao,S.,
            Liu,M., Song,S. and Wang,L.
  TITLE     Overexpression of PELP1 in Lung Adenocarcinoma Promoted E2 Induced
            Proliferation, Migration and Invasion of the Tumor Cells and
            Predicted a Worse Outcome of the Patients
  JOURNAL   Pathol Oncol Res 27, 582443 (2021)
   PUBMED   34257530
  REMARK    GeneRIF: Overexpression of PELP1 in Lung Adenocarcinoma Promoted E2
            Induced Proliferation, Migration and Invasion of the Tumor Cells
            and Predicted a Worse Outcome of the Patients.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5084)
  AUTHORS   Choi,Y.B., Ko,J.K. and Shin,J.
  TITLE     The transcriptional corepressor, PELP1, recruits HDAC2 and masks
            histones using two separate domains
  JOURNAL   J Biol Chem 279 (49), 50930-50941 (2004)
   PUBMED   15456770
  REMARK    GeneRIF: PELP1 recruits HDAC2 and masks histones using two separate
            domains
REFERENCE   7  (bases 1 to 5084)
  AUTHORS   Nair,S.S., Mishra,S.K., Yang,Z., Balasenthil,S., Kumar,R. and
            Vadlamudi,R.K.
  TITLE     Potential role of a novel transcriptional coactivator PELP1 in
            histone H1 displacement in cancer cells
  JOURNAL   Cancer Res 64 (18), 6416-6423 (2004)
   PUBMED   15374949
  REMARK    GeneRIF: Results provide novel insights about the transcription
            regulation of PELP1 and suggest that PELP1 participates in
            chromatin remodeling activity via displacement of histone 1 in
            cancer cells.
REFERENCE   8  (bases 1 to 5084)
  AUTHORS   Barletta,F., Wong,C.W., McNally,C., Komm,B.S., Katzenellenbogen,B.
            and Cheskis,B.J.
  TITLE     Characterization of the interactions of estrogen receptor and MNAR
            in the activation of cSrc
  JOURNAL   Mol Endocrinol 18 (5), 1096-1108 (2004)
   PUBMED   14963108
REFERENCE   9  (bases 1 to 5084)
  AUTHORS   Balasenthil,S. and Vadlamudi,R.K.
  TITLE     Functional interactions between the estrogen receptor coactivator
            PELP1/MNAR and retinoblastoma protein
  JOURNAL   J Biol Chem 278 (24), 22119-22127 (2003)
   PUBMED   12682072
  REMARK    GeneRIF: PELP1, a steroid coactivator, plays a permissive role in
            E2-mediated cell cycle progression, presumably via its regulatory
            interaction with the pRb pathway
REFERENCE   10 (bases 1 to 5084)
  AUTHORS   Vadlamudi,R.K., Wang,R.A., Mazumdar,A., Kim,Y., Shin,J., Sahin,A.
            and Kumar,R.
  TITLE     Molecular cloning and characterization of PELP1, a novel human
            coregulator of estrogen receptor alpha
  JOURNAL   J Biol Chem 276 (41), 38272-38279 (2001)
   PUBMED   11481323
  REMARK    GeneRIF: PELP1 is a coactivator of estrogen receptor (ER),
            interacts with ER, and may have a role in mammary tumorigenesis.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC417876.1, BC069058.1,
            AI927300.1, BC010457.2 and AC091153.10.
            
            On Dec 4, 2018 this sequence version replaced NM_014389.2.
            
            Summary: This gene encodes a transcription factor which coactivates
            transcription of estrogen receptor responsive genes and corepresses
            genes activated by other hormone receptors or sequence-specific
            transcription factors. Expression of this gene is regulated by both
            members of the estrogen receptor family. This gene may be involved
            in the progression of several types of cancer. Alternative splicing
            results in multiple transcript variants. [provided by RefSeq, May
            2013].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK299084.1, AK291163.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000572293.7/ ENSP00000460300.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                DC417876.1         201-226
            27-3028             BC069058.1         1-3002
            3029-3029           AI927300.1         438-438             c
            3030-3474           BC010457.2         2758-3202
            3475-5084           AC091153.10        110651-112260
FEATURES             Location/Qualifiers
     source          1..5084
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p13.2"
     gene            1..5084
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /note="proline, glutamate and leucine rich protein 1"
                     /db_xref="GeneID:27043"
                     /db_xref="HGNC:HGNC:30134"
                     /db_xref="MIM:609455"
     exon            1..275
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..3419
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /note="isoform 1 is encoded by transcript variant 1;
                     proline-, glutamic acid- and leucine-rich protein 1;
                     proline and glutamic acid rich nuclear protein;
                     transcription factor HMX3; modulator of non-genomic
                     activity of estrogen receptor"
                     /codon_start=1
                     /product="proline-, glutamic acid- and leucine-rich
                     protein 1 isoform 1"
                     /protein_id="NP_055204.4"
                     /db_xref="CCDS:CCDS58503.3"
                     /db_xref="GeneID:27043"
                     /db_xref="HGNC:HGNC:30134"
                     /db_xref="MIM:609455"
                     /translation="MAAAVLSGPSAGSAAGVPGGTGGLSAVSSGPRLRLLLLESVSGL
                     LQPRTGSAVAPVHPPNRSAPHLPGLMCLLRLHGSVGGAQNLSALGALVSLSNARLSSI
                     KTRFEGLCLLSLLVGESPTELFQQHCVSWLRSIQQVLQTQDPPATMELAVAVLRDLLR
                     YAAQLPALFRDISMNHLPGLLTSLLGLRPECEQSALEGMKACMTYFPRACGSLKGKLA
                     SFFLSRVDALSPQLQQLACECYSRLPSLGAGFSQGLKHTESWEQELHSLLASLHTLLG
                     ALYEGAETAPVQNEGPGVEMLLSSEDGDAHVLLQLRQRFSGLARCLGLMLSSEFGAPV
                     SVPVQEILDFICRTLSVSSKNISLHGDGPLRLLLLPSIHLEALDLLSALILACGSRLL
                     RFGILIGRLLPQVLNSWSIGRDSLSPGQERPYSTVRTKVYAILELWVQVCGASAGMLQ
                     GGASGEALLTHLLSDISPPADALKLRSPRGSPDGSLQTGKPSAPKKLKLDVGEAMAPP
                     SHRKGDSNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHDLVLPLVMGVQQGEVLG
                     SSPYTSSRCRRELYCLLLALLLAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEAL
                     VTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGP
                     MPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPIL
                     APSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL
                     PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP
                     PPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE
                     EDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEV
                     EEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA
                     LPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM
                     ETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS"
     exon            276..340
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            341..446
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            447..596
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            597..668
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            669..728
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            729..879
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1006
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1094
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1183
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1300
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1301..1448
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1608
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1664
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1871
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..3326
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     exon            3327..5084
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3449..3454
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /note="hexamer: AATAAA"
     polyA_site      3474
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /note="major polyA site"
     polyA_site      3734
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
     regulatory      5058..5063
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
                     /note="hexamer: ATTAAA"
     polyA_site      5084
                     /gene="PELP1"
                     /gene_synonym="MNAR; P160"
ORIGIN      
        1 acgccaccac tggaacccgg gggaagatgg cggcagccgt tctgagtggg ccctctgcgg
       61 gctccgcggc tggggttcct ggcgggaccg ggggtctctc ggcagtgagc tcgggcccgc
      121 ggctccgcct gctgctgctg gagagtgttt ctggtttgct gcaacctcga acggggtctg
      181 ccgttgctcc ggtgcatccc ccaaaccgct cggccccaca tttgcccggg ctcatgtgcc
      241 tattgcggct gcatgggtcg gtgggcgggg cccagaacct ttcagctctt ggggcattgg
      301 tgagtctcag taatgcacgt ctcagttcca tcaaaactcg gtttgagggc ctgtgtctgc
      361 tgtccctgct ggtaggggag agccccacag agctattcca gcagcactgt gtgtcttggc
      421 ttcggagcat tcagcaggtg ttacagaccc aggacccgcc tgccacaatg gagctggccg
      481 tggctgtcct gagggacctc ctccgatatg cagcccagct gcctgcactg ttccgggaca
      541 tctccatgaa ccacctccct ggccttctca cctccctgct gggcctcagg ccagagtgtg
      601 agcagtcagc attggaagga atgaaggctt gtatgaccta tttccctcgg gcttgtggtt
      661 ctctcaaagg caagctggcc tcattttttc tgtctagggt ggatgccttg agccctcagc
      721 tccaacagtt ggcctgtgag tgttattccc ggctgccctc tttaggggct ggcttttccc
      781 aaggcctgaa gcacaccgag agctgggagc aggagctaca cagtctgctg gcctcactgc
      841 acaccctgct gggggccctg tacgagggag cagagactgc tcctgtgcag aatgaaggcc
      901 ctggggtgga gatgctgctg tcctcagaag atggtgatgc ccatgtcctt ctccagcttc
      961 ggcagaggtt ttcgggactg gcccgctgcc tagggctcat gctcagctct gagtttggag
     1021 ctcccgtgtc cgtccctgtg caggaaatcc tggatttcat ctgccggacc ctcagcgtca
     1081 gtagcaagaa tattagcttg catggagatg gtcccctgcg gctgctgctg ctgccctcta
     1141 tccaccttga ggccttggac ctgctgtctg cactcatcct cgcgtgtgga agccggctct
     1201 tgcgctttgg gatcctgatc ggccgcctgc ttccccaggt cctcaattcc tggagcatcg
     1261 gtagagattc cctctctcca ggccaggaga ggccttacag cacggttcgg accaaggtgt
     1321 atgcgatatt agagctgtgg gtgcaggttt gtggggcctc ggcgggaatg cttcagggag
     1381 gagcctctgg agaggccctg ctcacccacc tgctcagcga catctccccg ccagctgatg
     1441 cccttaagct gcgtagcccg cgggggagcc ctgatgggag tttgcagact gggaagccta
     1501 gcgcccccaa gaagctaaag ctggatgtgg gggaagctat ggccccgcca agccaccgga
     1561 aaggggatag caatgccaac agcgacgtgt gtgcggctgc actcagaggc ctcagccgga
     1621 ccatcctcat gtgtgggcct ctcatcaagg aggagactca caggagactg catgacctgg
     1681 tcctccccct ggtcatgggt gtacagcagg gtgaggtcct aggcagctcc ccgtacacga
     1741 gctcccgctg ccgccgtgaa ctctactgcc tgctgctggc gctgctgctg gccccgtctc
     1801 ctcgctgccc acctcctctt gcctgtgccc tgcaagcctt ctccctcggc cagcgagaag
     1861 atagccttga ggtctcctct ttctgctcag aagcactggt gacctgtgct gctctgaccc
     1921 acccccgggt tcctcccctg cagcccatgg gccccacctg ccccacacct gctccagttc
     1981 cccctcctga ggccccatcg cccttcaggg ccccaccgtt ccatcctccg ggccccatgc
     2041 cctcagtggg ctccatgccc tcagcaggcc ccatgccttc agcaggcccc atgccctcag
     2101 caggccctgt gccctcggca cgccctggac ctcccaccac agccaaccac ctaggccttt
     2161 ctgtcccagg cctagtgtct gtccctcccc ggcttcttcc tggccctgag aaccaccggg
     2221 caggctcaaa tgaggacccc atccttgccc ctagtgggac tcccccacct actatacccc
     2281 cagatgaaac ttttgggggg agagtgccca gaccagcctt tgtccactat gacaaggagg
     2341 aggcatctga tgtggagatc tccttggaaa gtgactctga tgacagcgtg gtgatcgtgc
     2401 ccgaggggct tccccccctg ccacccccac caccctcagg tgccacacca ccccctatag
     2461 cccccactgg gccaccaaca gcctcccctc ctgtgccagc gaaggaggag cctgaagaac
     2521 ttcctgcagc cccagggcct ctcccgccac ccccacctcc gccgccgcct gttcctggtc
     2581 ctgtgacgct ccctccaccc cagttggtcc ctgaagggac tcctggtggg ggaggacccc
     2641 cagccctgga agaggatttg acagttatta atatcaacag cagtgatgaa gaggaggagg
     2701 aagaggaaga agaggaagaa gaagaagagg aagaagagga agaggaggaa gactttgagg
     2761 aagaggaaga ggatgaagag gaatattttg aagaggaaga agaggaggaa gaagagtttg
     2821 aggaagaatt tgaggaagaa gaaggtgagt tagaggaaga agaagaagag gaggatgagg
     2881 aggaggaaga agaactggaa gaggtggaag acctggagtt tggcacagca ggaggggagg
     2941 tagaagaagg tgcacctcca cccccaaccc tgcctccagc tctgcctccc cctgagtctc
     3001 ccccaaaggt gcagccagaa cccgaacctg aacccgggct gcttttggaa gtggaggagc
     3061 cagggacgga ggaggagcgt ggggctgaca cagctcccac cctggcccct gaagcgctcc
     3121 cctcccaggg agaggtggag agggaagggg aaagccctgc ggcagggccc cctccccagg
     3181 agcttgttga agaagagccc tctgctcccc caaccctgtt ggaagaggag actgaggatg
     3241 ggagtgacaa ggtgcagccc ccaccagaga cacctgcaga agaagagatg gagacagaga
     3301 cagaggccga agctctccag gaaaaggagc aggatgacac agctgccatg ctggccgact
     3361 tcatcgattg tccccctgat gatgagaagc caccacctcc cacagagcct gactcctagc
     3421 catcttctgc accccactct ttgtttccaa taaagttatg tccttagata gcgactgctg
     3481 cttctgcctt ttgccacacc tgggtcccca gccagaagct caagtgtctg ctgggctttt
     3541 cagggtgtcc atagtattcc ccagatgtct ccatagctgt cctctttttg acgatccaga
     3601 gaggaacaac tgacattggt gtaatggact gtcccatcac tcagcacgat ggtgtcagaa
     3661 ttgtaggatt ctggctggat gctaaacgtg cagaattgtg tgtagggtta agaatgagga
     3721 gttatagaga cacagccctg ctttcgtgtt tgtattcggg gtgggaaatg tgtggagaat
     3781 gcatcctagt gagtggacct gtgtcaacac ccacatgccc acacgcatgc gtgctcagcc
     3841 ccttggtctg aaagggcagg ctgagtgatt gctcagtcta tggaagttta ggaaattagg
     3901 aaaaggtgtg gagcagttta gtcattgaat tctgggaaat ttggacctta ccccaagatg
     3961 aaagggtgtc cgtagtgggt acgttgggaa tgacctctgt tttggggcta gtcctcctaa
     4021 tgacagttcc cctcacagct ccctggcagg agtttgataa gctcacccca ggccttcctg
     4081 ctcactcttg aggtgtggat atttcccacc cagtgtcttt tcttttcttt ttttttttga
     4141 gatggactcc tgctctgtcg cccaggctgg agtgcagtgg catggtctca gctcactgca
     4201 acctctgcct cccaggttca agcaattctc tgcctcagcc tcctgagtag ctgggattac
     4261 aggcgcctgc cactgcctgg ctaatttttg tatttttagt agaggtgggg tttcaccatg
     4321 ttggccaggc tggtcttgaa ctcctgagct catggtccac ctgccttgga ctcccaaagt
     4381 gctgggatca caagcatgag acaccgcacc tgactgtccc agtgtctttt ctttaagcac
     4441 taatcctatt ctaggccttg ctgggatgga cgtgtgagga tgaaccgaga gatgtgtctg
     4501 tgagagggta ccaagattgg tgggcttgaa ctaggggccc cgtggttttt tttgctcagt
     4561 cagttgaatc atgaacgtaa gtaaagtgcc ttcgcaatgc agaagaggga gtcatttctc
     4621 ccaacatgta tcctgaagag ccctttgagg aggtggcatt tgagctaatt tttggaaact
     4681 tcagtaggat tttaaaaagt tacccctcaa cttgttttcg aaataaacag aaaagtgaga
     4741 acagtataat agataacctt tgcctagatt tgccaattaa catttagtca tgttaactct
     4801 tatccctata aactgcgtat ctacatgtag acatgtatct atattacacc catatatctg
     4861 tctaatctat acatctgtag ttatacacat ttcttttttc atgggaccac gtgaaagtaa
     4921 gctgtagaca ccgtggccct tcccatccca gattctttaa catgaattat cttctaagat
     4981 aagaatgttt ttctgcacaa tcctgatacc attatcaaac ctaagaaaaa taacagtaat
     5041 ccagtgataa ttgtgatatt aaaattttcc tattaattcc taaa
//
