LOCUS       XM_017021478            8295 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens pellino E3 ubiquitin protein ligase family
            member 2 (PELI2), transcript variant X1, mRNA.
ACCESSION   XM_017021478
VERSION     XM_017021478.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017021478.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8295
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..8295
                     /gene="PELI2"
                     /note="pellino E3 ubiquitin protein ligase family member
                     2; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 5 ESTs, 753 long SRA reads, 13
                     Proteins, and 95% coverage of the annotated genomic
                     feature by RNAseq alignments, including 68 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:57161"
                     /db_xref="HGNC:HGNC:8828"
                     /db_xref="MIM:614798"
     CDS             2714..3937
                     /gene="PELI2"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase pellino homolog 2
                     isoform X1"
                     /protein_id="XP_016876967.1"
                     /db_xref="GeneID:57161"
                     /db_xref="HGNC:HGNC:8828"
                     /db_xref="MIM:614798"
                     /translation="MLAWPFHSNVVLGYNGALPNGDRGRRKSRFALYKRPKANGVKPS
                     TVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFV
                     VTDTISGSQNTDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAA
                     KWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGK
                     LVESETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLN
                     TLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPL
                     WLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLV
                     GEQNCIKLIFQGPID"
ORIGIN      
        1 caggtgattc tgatgttcac tttgtattga aaacaactct aaaatttttc tctaatcctc
       61 cagttcatct ccaccatcgc tgctttggtt caggctttta tagtttcctg tggctgccat
      121 aacacattac cacaaacttg gtaacaacaa cagatgttca ttctcttaca gttctagagg
      181 ccacaagtct gaaatcaagg tgtcggcagg gccctgctgc ccctgaaggc tcttaagggg
      241 agaatctttc cttgcctctt ccagcttctg gggctccaaa tgttccttgg cttgtggttg
      301 catcacccca gtctctgcct ccatcacatg gtcgtctcct ctctatccct gtgtacctcc
      361 tacaaaatca cttgccattg gatttaggac ctatcgacct aacagtaatc gaggatgatc
      421 tcatcttgag atcctgggct taattacatc tgcaaacacc gcttttccaa aaggtcacat
      481 tcacaagtga catggatgta tctttttctt ttgagactga gtcttgctct gtcgcccagg
      541 ctggagtaca gtggtacgat ctcggcccac tgaaacctct gcttcctggg ttcaagtgat
      601 tctcctgcct cagcctctca agtagctggg attacaggca tgtgctatca tgcccagcta
      661 attttttgta ttttaagtag agacagggtt tcaccacgtt ggccaggctg gtttcgaact
      721 cctgacctca agtgatccac ccgcctcggc ctcccaaagt gccgggatta caggcatgag
      781 ccatcatgcc cagccttgga tttatctttt taaggccacc attcaatcca ctgtacatag
      841 atccccatgg ctatggtgct gctgctgtct gatcatcttg cctctaatct ggtctggtct
      901 tgcctctaat ttcttccagt tcctcctgca ctgtgccacc ctatgtgatt actttatatt
      961 tccagtcatg ttagccattt gcttaaatct taccagactt ttcattcccc ttagggtaaa
     1021 aagccataac ccttagggag taccagtgat agggtttagc tctgtgtccc cacccaaatc
     1081 tcatcttgaa ttgtgattcc tgtgtgtcag aggaggggcc tggcaggagg cgattggatg
     1141 gcggggtggg ggttggattt cccccttgct gttctcgtga tagtgaatga gttctcacaa
     1201 gatctgatgg tttaaaagtg tgtgtcactt tccccttctc gagctttctc tctcctgttg
     1261 ccgtgagaag aaggtgattg tttccccttt ggcttctgtc atgattgtaa gtttcttgag
     1321 gcttcccagt cgagcttctt gttaagcctg tggaactttt gagtcagtta aacctctttt
     1381 cttcacaggt agttctttac agcagtgtga gaatggacta atacaaccag gacgttacag
     1441 tcgggctcct gcctaccttt taccctcctt tcccactact ctctccactt gaacttcata
     1501 ctctccacag tgctgaactg tgtagtcctc cttgccttgc acattatatc accccttcat
     1561 tctccattta gacttcttac ttagatttct ttttctttct tttctttttt gacagtcttg
     1621 ctttgtcacc caggctggag tacagtggca tgatcttggc tcactgtagt ctccactttc
     1681 ctggctcaag tgatcttccc acctcagccg cccgagtagc cgtgactaca ggtgcatgcc
     1741 accacaccag gctaattttc gtattttttg tagaggtggg gttttgacac attgcccagg
     1801 ctggtctcga actcctgggc tcaagctgtc tacctgcctc ggcctcccaa agtgctggaa
     1861 ttacaggcat gagccaacgt gcctggccaa gatttcgaca gttcaagcag tgcttccacc
     1921 atgaagcctt ctctaatgcg tcctgccatg tgccttgtgc tataagtgca tcttgttaca
     1981 tgtgtattta tcatatttgt tattgtgcct ttctctcctt ctgagcagag agctctgtga
     2041 aggcagggaa gctgatatac accattgtag ctctagtact tggcattatg aatattgaat
     2101 gaatgaccat gtagcttaac ctaattagaa acttgtctca tggtgacact ggtttttcca
     2161 gtgctacttt aattatttcc aataggattt ttcatctaga tgtattaagt aagtaggcag
     2221 tctgtaagta ggctggctta ttatttgctt aacctgcaat atctgtgcct ctatgcttag
     2281 gcaatttaaa ttaaaatgtt tctgcatgtg ttaaggttga cacttctggt ttttttccct
     2341 ccctttatat tagatatgac ttttgggttg taactcgtgg aaatcaaatt gagttagctg
     2401 aagctgaagg aattttgtca agaatggctg gagtacatct gggccaatag aaacccttaa
     2461 ggatcctctt tccattgctt tttgtgcttg tctctgttct gcttccttct tcactttgtc
     2521 tgctttttca gccatataac actttatgac atccccacag ctcctgtgtt tacattttac
     2581 agctctagcc agcaactgag aatggatgac tatctctctg tcccaatttt gtattttcca
     2641 aaactagaat gttattggcc aggttgagtc agatgtcagc ctctggccag tcagccccag
     2701 agtggtgggg aagatgttgg catggccatt tcattcaaac gtggtgctgg ggtacaatgg
     2761 tgctttaccc aatggagata gaggacggag gaaaagtaga tttgccctct acaagcggcc
     2821 caaggcaaat ggtgtcaaac ccagcaccgt ccatgtgata tccacgcccc aggcatccaa
     2881 ggctatcagc tgcaaaggtc aacacagtat atcctacact ttgtcaagga atcagactgt
     2941 ggtggtggag tacacacatg ataaggatac ggatatgttt caggtgggca gatcaacaga
     3001 aagccctatc gacttcgttg tcacagacac gatttctggc agccagaaca cggacgaagc
     3061 ccagatcaca cagagcacca tatccaggtt cgcctgcagg atcgtgtgcg acaggaatga
     3121 accttacaca gcacggatat tcgccgccgg atttgactct tccaaaaaca tatttcttgg
     3181 agaaaaggca gcaaagtgga aaaaccccga cggccacatg gatgggctca ctactaatgg
     3241 cgtcctggtg atgcatccac gagggggctt caccgaggag tcccagcccg gggtctggcg
     3301 cgagatctct gtctgtggag atgtgtacac cttgcgagaa accaggtcgg cccagcaacg
     3361 aggaaagctg gtggaaagtg agaccaacgt cctgcaggac ggctccctca ttgacctgtg
     3421 tggggccact ctcctctgga gaacagcaga tgggcttttt catactccaa ctcagaagca
     3481 catagaagcc ctccggcagg agattaacgc cgcccggcct cagtgtcctg tggggctcaa
     3541 caccctggcc ttccccagca tcaacaggaa agaggtggtg gaggagaagc agccctgggc
     3601 atatctcagt tgtggccacg tgcacgggta ccacaactgg ggccatcgga gtgacacgga
     3661 ggccaacgag agggagtgtc ccatgtgcag gactgtgggc ccctatgtgc ctctctggct
     3721 tggctgtgag gcaggatttt atgtagacgc aggaccgcca actcatgctt tcactccctg
     3781 tggacacgtg tgctcggaga agtctgcaaa atactggtct cagatcccgt tgcctcatgg
     3841 aactcatgca tttcacgctg cttgcccttt ctgtgctaca cagctggttg gggagcaaaa
     3901 ctgcatcaaa ttaattttcc aaggtccaat tgactgacgc ccttgacagc catctacgac
     3961 tttattaaca ggttactgtg aagattttgc cactaactct agattttacc tttttgtaat
     4021 gctgtttatc agaggagggt gacaggggct ggaaataaag agaggggaca tggtgatgaa
     4081 acatggcagg agtgtaacag ataccagtgg tgtgttgcat gctcaaaaca gcagcgtcgt
     4141 cattgaagtc tgcttgatta aaccataata tctttgtaat aattggattt aaaatgctat
     4201 gcttctattt ttaaccttgg gtttttaacc aagttttttt ttttttgtaa tcttggacaa
     4261 gactttaaat catattttac agatgtagaa gaaatttatt caaaagtgtg ggctcatgaa
     4321 gttcacttca gtgcagtgtg gtgtaggtgt tacgcgaagg gcgcacagtg tctagaaata
     4381 cttgatcgtg gctcaaacct gaccagacag cagaggggcg gctctgtaca gtgtgactgg
     4441 tggacagatg gccttaggca caggtggttt tgaaatctgg ggctttttct gatttatttt
     4501 tctgacttgt tgggggagag aatattcata acttgtgggc tttttttttt tttaacttca
     4561 gtggaattta ctttagatat tcattcatca aatacatggg acttcacaaa caattttcca
     4621 taacttttta gcctgtcttt tgttatttct gcctaatatg atttgccccg atactcatct
     4681 tgcacggcca gaactgtttg gttgattaaa atacatcagc tcttaaaaac tcattaactg
     4741 agggtaatta cagtagtaga catggtctgg gtactatact accatgttta tttgctgact
     4801 gaattaagat ttaagaatga ttaaaaataa gcttttactt tttaaaacca cttgaggttt
     4861 cataaagctt ggggtttttt tttttccttt gttaagaaag ccaaccaatc acaatgatat
     4921 agtcattgtt gtgcactccc ttttcaccat ctgtcacctt cccttgcagc ttaaggagcc
     4981 cagtaagttt tgaaaatgtt tgcgaatcaa actaaattta agtgggatga ttagatatac
     5041 acaacaccaa gtggtacatc tgcagagata attcaaaatt cctgcttttg agagagcaaa
     5101 tgagtgttgc tgaggaataa ttaaatgaga atttcatagg agctccacca ttcctgttac
     5161 tttcatttca ttttgattaa taattcttgg atgcttggca tcgatcgtat cactgctcct
     5221 agaaggtaaa gatcctttag gacatgagac tggtagaagc tggctgagat aaaataagta
     5281 tttatttaaa ctaatgttct cttaatttga ccattgcaga tttgggtgac ttttttttaa
     5341 cctttgtaca tatacgtaat ttatatgatt ctaatgtact atatccatac ttgaattggt
     5401 tttttcgtat tttgcctact ggcaaatatt ttgcctattt tcagtcgttc taacctattt
     5461 gaatacgctt ttccttaaag tgatacgata atattactct tgattgctgc tgcttaattt
     5521 gatgtaatat gtttaaagtt cagcctctca gttttaatat agctttattt ttcagtggag
     5581 atcattgttt aggatgagac atttttggtt ttggttttgt ttgggtaaat tttaaatggt
     5641 gtgaaaatcg atgacaacag tcctcttaca gatagcttgc tgtattctgt atagcttact
     5701 ctacctgcag acagaaaatg aaagaaaaaa atggacttgc ctagaataat atattgaatg
     5761 ccttttgatt tagccagagt ctctgatgat tagctttcac tgatagagta tgtcttttca
     5821 gcctgtaatt ctttgggccc caaagaatga caaaggaggc actcgttctc ttttcttgct
     5881 gtatgcctag aaagtggttg aaggattctt gatgccctaa aaccatcttg taagctaaat
     5941 ggtcttgcat ccagaaaggc cagattttac ctaccaagaa aaaaagatat ttttccagag
     6001 agttaggtat atcataattt tccatttcaa gtcctgttta taagtctagt cattctgcaa
     6061 cgtgacatat cccccaaaat gaagttacct tccaagttgg acacgtcccg tagttgggca
     6121 tatgtctaac taaaagtttc tgacttttag taaattcagc ttaaatataa gttgaaattt
     6181 gggaaataat ttccaagctc ttggaagggg taacagtgaa ccgccctcca tgggctccac
     6241 atcttttcct ttggcttcca aagtcaggtc ccgcccaccc tgcctaagga actgcagaga
     6301 ggtggcaaat cagcaaaaag gacaccaggc tcttcttggc cacttgtagg aagatccctt
     6361 tacaattttg actaaggaga tttttttttt cacagttgag ttagtttgtg aaaataaaga
     6421 actctgtagc tcaccaaggt ggagaaacgc aattcagaaa agtaatttct ccaaggtcac
     6481 ttcttttttt atgtcttgcc atcactttaa aggactagcc ccactccccc atgtgtatac
     6541 acaaggaaat tgcagaccaa ttagttgtct tggcctgact ctaatgcctt ttgcaagtag
     6601 ctttccagaa gtaaaagtcc cagtgatgta ttcccataga aatatttttc agttgtttat
     6661 gtcgtttact acaaaaaaaa agattcagag tggatggagt acaactctga gtatttttct
     6721 agtccggaat tttttattaa taatcggtgc tgccgggtca tgcatgctgc aactctcaac
     6781 atttccctta tttggttcag cttttagcaa aaagggctac agttcaccct gcagagtatt
     6841 aaggtttctg gatttttttc tcccaactgt ggcccaaaag aattaaaatc tgttaatata
     6901 aatagagaac atatttatca ttcctcgata gttaattata gactttggta cctttgtgcc
     6961 tcagggaagc cacgtgatat aactggttat agaatttcag ggttagggtt taaagaaagg
     7021 agaaagccat tggaaaaatg atgggctcca ttaaggagac taatgaatct ggatgcagaa
     7081 atatgtcaga aactggcata aacatgattg tagtagaatt tattttccag taccaatagg
     7141 gaaattattt taagttatta catttactgt attgggaaac ttgaggagaa ctctttagtt
     7201 cataaagctt caatgtcttt tttttttttt tcatggaaaa actcaaacct ctgttatttg
     7261 ggagctcagt attgtgtgga cacttacgag agttttctgc ttaattgaag tgtaatatag
     7321 gttgtagaat tgttacctgc agttctatgg ttttgtttca cttcttttct tttttaaagc
     7381 cattctgttc tttggatgtg cttgaaaggg tgtgtgatta caccattgtt aatgctgggt
     7441 aaaaactatc ttcttgcagc cttgcctcat aacagtggaa tttctgatag acaaaccaca
     7501 ggactttgat tttaagccaa atccatctcc atccctttac tgtcaatctt ctgtcccagt
     7561 agtttagcct ttgtggctta ggttatgatg cgcctccttc tgtgcgacca atgagacgac
     7621 ttcagcatct ttttaaaata atctaagcat cattgaagca gtaacacaaa aaaaaggttc
     7681 agtattttct ttttagtata acttacatcc tttcaaataa gtctttgccc tcatgaagaa
     7741 tccctagagg aagataagga aaataagtat tttccagttt tgcttgacag tttctaaaca
     7801 aacaaaaata aactcaatga aaggaaagat gtttcttttt agctgagatg acagattgct
     7861 tctctgtatt aaatagtcta gaagttaagg ggatggtcac atttaccatg tattgtgtta
     7921 ttagcagtta aattttatga atatgtttgt aaaattgttg ttttatattt catgtcaaat
     7981 tgaaaagttt atttcttcac tattgtacct gtggaaatac aagccatttt acaggaaaaa
     8041 atcttcaaaa actattaaat ggatatcagc ctgtttgtga gccattgtct tcagattctg
     8101 tggttgtcac tgagttcatt aggacattta gtaggttgat acgagtagaa ctgatttttt
     8161 tcacttctct aacttccaag ttaatctcca gctgttgagt ttattaattg ttttatattc
     8221 tgcacaatac atatttaaac cttgattctg aaaatcccct acatttttta attaaagaaa
     8281 tttccttggt gccta
//
