LOCUS       NM_001363519            1266 bp    mRNA    linear   PRI 08-FEB-2024
DEFINITION  Homo sapiens PDZ domain containing 9 (PDZD9), transcript variant 3,
            mRNA.
ACCESSION   NM_001363519
VERSION     NM_001363519.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1266)
  AUTHORS   Martin,J., Han,C., Gordon,L.A., Terry,A., Prabhakar,S., She,X.,
            Xie,G., Hellsten,U., Chan,Y.M., Altherr,M., Couronne,O., Aerts,A.,
            Bajorek,E., Black,S., Blumer,H., Branscomb,E., Brown,N.C.,
            Bruno,W.J., Buckingham,J.M., Callen,D.F., Campbell,C.S.,
            Campbell,M.L., Campbell,E.W., Caoile,C., Challacombe,J.F.,
            Chasteen,L.A., Chertkov,O., Chi,H.C., Christensen,M., Clark,L.M.,
            Cohn,J.D., Denys,M., Detter,J.C., Dickson,M.,
            Dimitrijevic-Bussod,M., Escobar,J., Fawcett,J.J., Flowers,D.,
            Fotopulos,D., Glavina,T., Gomez,M., Gonzales,E., Goodstein,D.,
            Goodwin,L.A., Grady,D.L., Grigoriev,I., Groza,M., Hammon,N.,
            Hawkins,T., Haydu,L., Hildebrand,C.E., Huang,W., Israni,S.,
            Jett,J., Jewett,P.B., Kadner,K., Kimball,H., Kobayashi,A.,
            Krawczyk,M.C., Leyba,T., Longmire,J.L., Lopez,F., Lou,Y., Lowry,S.,
            Ludeman,T., Manohar,C.F., Mark,G.A., McMurray,K.L., Meincke,L.J.,
            Morgan,J., Moyzis,R.K., Mundt,M.O., Munk,A.C., Nandkeshwar,R.D.,
            Pitluck,S., Pollard,M., Predki,P., Parson-Quintana,B., Ramirez,L.,
            Rash,S., Retterer,J., Ricke,D.O., Robinson,D.L., Rodriguez,A.,
            Salamov,A., Saunders,E.H., Scott,D., Shough,T., Stallings,R.L.,
            Stalvey,M., Sutherland,R.D., Tapia,R., Tesmer,J.G., Thayer,N.,
            Thompson,L.S., Tice,H., Torney,D.C., Tran-Gyamfi,M., Tsai,M.,
            Ulanovsky,L.E., Ustaszewska,A., Vo,N., White,P.S., Williams,A.L.,
            Wills,P.L., Wu,J.R., Wu,K., Yang,J., Dejong,P., Bruce,D.,
            Doggett,N.A., Deaven,L., Schmutz,J., Grimwood,J., Richardson,P.,
            Rokhsar,D.S., Eichler,E.E., Gilna,P., Lucas,S.M., Myers,R.M.,
            Rubin,E.M. and Pennacchio,L.A.
  TITLE     The sequence and analysis of duplication-rich human chromosome 16
  JOURNAL   Nature 432 (7020), 988-994 (2004)
   PUBMED   15616553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC092119.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.346002.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148874, SAMEA2151119
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000424898.3/ ENSP00000400514.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC092119.3         133559-133658       c
            101-280             AC092119.3         128864-129043       c
            281-470             AC092119.3         121144-121333       c
            471-1266            AC092119.3         116407-117202       c
FEATURES             Location/Qualifiers
     source          1..1266
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p12.2"
     gene            1..1266
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /note="PDZ domain containing 9"
                     /db_xref="GeneID:255762"
                     /db_xref="HGNC:HGNC:28740"
     exon            1..100
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..864
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /note="isoform 3 is encoded by transcript variant 3; PDZ
                     domain-containing protein C16orf65; PDZ domain-containing
                     protein 9"
                     /codon_start=1
                     /product="PDZ domain-containing protein 9 isoform 3"
                     /protein_id="NP_001350448.1"
                     /db_xref="CCDS:CCDS92124.1"
                     /db_xref="GeneID:255762"
                     /db_xref="HGNC:HGNC:28740"
                     /translation="MQKASHKNKKERGVSNKVKTSVHNLSKTQQTKLTVGSLGLGLII
                     IQHGPYLQITHLIRKGAAANDGKLQPGDVLISVGHANVLGYTLREFLQLLQHITIGTV
                     LQIKVYRDFINIPEEWQEIYDLIPEAKFPVTSTPKKIELAKDESFTSSDDNENVDLDK
                     RLQYYRYPWSTVHHPARRPISISRDWHGYKKKNHTISVGKDINCDVMIHRDDKKEVRA
                     PSPYWIMVKQDNESSSSSTSSTSDAFWLEDCAQVEEGKAQLVSKVG"
     exon            101..280
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /inference="alignment:Splign:2.1.0"
     exon            281..470
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /inference="alignment:Splign:2.1.0"
     exon            471..1266
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1244..1249
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /note="hexamer: ATTAAA"
     polyA_site      1266
                     /gene="PDZD9"
                     /gene_synonym="C16orf65"
                     /note="major polyA site"
ORIGIN      
        1 gttggcattg ggactgactc cagcctctgc tccgggaggc cctcccgggc tgcctgacct
       61 cccgggacca tgcagaaggc ctcccacaaa aacaaaaaag aaagaggagt cagcaacaag
      121 gtcaaaacat ctgtacacaa cttgagcaaa acacagcaga ccaaactcac tgtgggtagc
      181 ctgggattag gcctcatcat catccagcat ggaccctacc tccagatcac ccacctcatc
      241 aggaaggggg ctgcagccaa cgacgggaaa ctccagccag gtgatgttct gattagtgtt
      301 ggccatgcca atgtgttagg atatactctt cgagaatttt tacagctttt gcaacatatc
      361 actattggaa cagtgctaca aatcaaggtt taccgagatt ttattaacat tcctgaagaa
      421 tggcaagaaa tatatgattt aatccctgag gccaaattcc cagtaacaag cacaccaaag
      481 aaaattgagc tggcaaaaga tgaatctttc acaagcagtg atgataatga aaatgtagat
      541 ttagataaaa gacttcaata ttatagatat ccgtggtcaa ctgtgcatca ccctgcaagg
      601 agaccaatat ccatctccag agactggcat ggatataaga agaagaacca tactattagt
      661 gtaggaaaag acattaattg tgacgtgatg attcacagag acgacaagaa agaagtgagg
      721 gccccttctc catactggat aatggtgaag caagacaatg aaagctcttc ctcctctacc
      781 tcctctacct cagatgcatt ttggctggaa gattgtgccc aagttgaaga gggtaaagcc
      841 caactggtat caaaggttgg ttagcaaatc tgtggtcata tgagcattta tcttgcagac
      901 acccaagttt tgtgcctcac caggcacaag tttgctgtac ttatcaagga ctgtctgtag
      961 actcaccaat tctcttctct tatgactgcg ttataaagcc tttagagatg ttcttcaaca
     1021 ggattatcta aagacttcct tgggttcttg caggcctcac aaatcttatt ttcagaataa
     1081 gaccctcctt tttgagaaga atttctttct tttagaaaat gccgtagaga aatccaatat
     1141 cagaatgtct gaacatagta gagaatgtca ctttatgtaa acactacatt tttctttaaa
     1201 tatttagttt ctctcttttt tttggtaaac ttcaagtact ataattaaaa taactaagag
     1261 acataa
//
