LOCUS       XM_017027878            2456 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens prodynorphin (PDYN), transcript variant X6,
            mRNA.
ACCESSION   XM_017027878
VERSION     XM_017027878.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000020.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2456
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
     gene            1..2456
                     /gene="PDYN"
                     /gene_synonym="ADCA; PENKB; SCA23"
                     /note="prodynorphin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 7 ESTs, 15 long
                     SRA reads, 4 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 6 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:5173"
                     /db_xref="HGNC:HGNC:8820"
                     /db_xref="MIM:131340"
     CDS             125..889
                     /gene="PDYN"
                     /gene_synonym="ADCA; PENKB; SCA23"
                     /codon_start=1
                     /product="proenkephalin-B isoform X1"
                     /protein_id="XP_016883367.1"
                     /db_xref="GeneID:5173"
                     /db_xref="HGNC:HGNC:8820"
                     /db_xref="MIM:131340"
                     /translation="MAWQGLVLAACLLMFPSTTADCLSRCSLCAVKTQDGPKPINPLI
                     CSLQCQAALLPSEEWERCQSFLSFFTPSTLGLNDKEDLGSKSVGEGPYSELAKLSGSF
                     LKELEKSKFLPSISTKENTLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGAMETGT
                     LYLAEEDPKEQVKRYGGFLRKYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRIRPKL
                     KWDNQKRYGGFLRRQFKVVTRSQEDPNAYSGELFDA"
ORIGIN      
        1 acttcattac cttcagatca accagaatta tcattcaata taaagttaat ggatgaaaga
       61 caaggatgcc aatgctgttt ttgcctgaga taaagagatc ttaaccagga attgctgaga
      121 caggatggcc tggcaggggc tggtcctggc tgcctgcctc ctcatgttcc cctccaccac
      181 agcggactgc ctgtcgcggt gctccttgtg tgctgtaaag acccaggatg gtcccaaacc
      241 tatcaatccc ctgatttgct ccctgcaatg ccaggctgcc ctgctgccct ctgaggaatg
      301 ggagagatgc cagagctttc tgtctttttt caccccctcc acccttgggc tcaatgacaa
      361 ggaggacttg gggagcaagt cggttgggga agggccctac agtgagctgg ccaagctctc
      421 tgggtcattc ctgaaggagc tggagaaaag caagtttctc ccaagtatct caacaaagga
      481 gaacactctg agcaagagcc tggaggagaa gctcaggggt ctctctgacg ggtttaggga
      541 gggagcagag tctgagctga tgagggatgc ccagctgaac gatggtgcca tggagactgg
      601 cacactctat ctcgctgagg aggaccccaa ggagcaggtc aaacgctatg ggggcttttt
      661 gcgcaaatac cccaagagga gctcagaggt ggctggggag ggggacgggg atagcatggg
      721 ccatgaggac ctgtacaaac gctatggggg cttcttgcgg cgcattcgtc ccaagctcaa
      781 gtgggacaac cagaagcgct atggcggttt tctccggcgc cagttcaagg tggtgactcg
      841 gtctcaggaa gatccgaatg cttactctgg agagcttttt gatgcataag cacctctttt
      901 catggagtag agtcaggaga aacccctgac accttttcag gttggagtgc attcattcat
      961 cctcttatat gtgccccttc cccatgctca gctcagcatt gtgtacaaaa tatccaagcc
     1021 cagcctatct ctcttctgcg tgggagtatg ttatttctct ggggtctgtg atggggaagg
     1081 gtggatgtcc cttccccaca ataggcttag tgcttggctc agacacctag actctaaaac
     1141 tatcagcagc ggcagcagca gcagcagcag cagtttgtga tctgtccttc caacctgttc
     1201 acgtgactcc tcaattccag ggaaccagag cgatgtgttc tttgtacctg taggtctatg
     1261 atgtccaaac ttaacagatc acatgcccct cttagaagaa atatgagcat gctccctcat
     1321 gcagatagta tacacatcat aaacaaagag tagaacttta aaagaaggta aataatcata
     1381 cacagaaatc ctaacattat attcccaaat ctcaaaagat ctcctgtgca cctgactttg
     1441 gagacgatgc tttaggtaaa aagcttaaac attgccttat attggatcag gaacccttac
     1501 agtagagggt ccagtcttct agtgggttta atgtttagtc agtgtactct gagtcctcat
     1561 tgttcagaaa agcacctctt gaagaactga cttcctgaac tcccagtcat gttggtaccc
     1621 tggacagtgc ctaactcctt acagaaggga gtgaaaacct ctttcggaaa tgattgagag
     1681 cagcctcttg aatgcttaaa tgatcaagga gggagaaagg caaaccaatt tgttctgtgc
     1741 aacaaactca aaatgtggac cagttccctc agccctcatt aaactaatta aactgatggg
     1801 tatcatgctt ctactccatg gtgaactgaa gcagagtcaa gctgatgaag ttaagcacaa
     1861 ccatgttctt gagcagctga attggctgcc aagagtccaa gccatctggc ccaacatacg
     1921 cactgggcat tgggtaaggg actccagaag cagcagctag aaagagaaaa agccctcttc
     1981 aatccccata atgcttcttt cctcttaatg tctcaaaata aaaccagaaa gaggaataaa
     2041 atgattaagt gcttgaggcc aaatgagttc ccttgattca aataaccctg aatcagaggc
     2101 agagacctcc tgatgtcttg gtttccatca aagccctccc tgtctgtctg tctctctttt
     2161 gctctctcat tcccaggcac tctcttttgg tttgtgggtc caggagatga ggctggatag
     2221 gagaggaaaa ggcttgagtc tggataattt gtataagatg ctgctgagca catctcttca
     2281 tgcgcagtcc ccaggtatct gatgatgttc tgaaatggat agattgtttt agagttattt
     2341 tgtgtccttt aaaaaaatcc catttatgca atttacttgg aatttgctta gcctttaata
     2401 ggcttgtgta atttcctgct cctccagtac aataaataaa agaaagatgc tgatga
//
