LOCUS       XM_017020452            7364 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens PDS5 cohesin associated factor B (PDS5B),
            transcript variant X6, mRNA.
ACCESSION   XM_017020452
VERSION     XM_017020452.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000013.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017020452.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7364
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
     gene            1..7364
                     /gene="PDS5B"
                     /gene_synonym="APRIN; AS3; CG008"
                     /note="PDS5 cohesin associated factor B; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 59 ESTs, 3956 long SRA reads, 6 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 137 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23047"
                     /db_xref="HGNC:HGNC:20418"
                     /db_xref="MIM:605333"
     CDS             162..4397
                     /gene="PDS5B"
                     /gene_synonym="APRIN; AS3; CG008"
                     /codon_start=1
                     /product="sister chromatid cohesion protein PDS5 homolog B
                     isoform X4"
                     /protein_id="XP_016875941.1"
                     /db_xref="GeneID:23047"
                     /db_xref="HGNC:HGNC:20418"
                     /db_xref="MIM:605333"
                     /translation="MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMD
                     MDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDK
                     LKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRT
                     LFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLA
                     KALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQ
                     LEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIRLECV
                     KFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDHLLNF
                     VRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDAAKQIAWIKDKLLHIYYQNSID
                     DRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKD
                     LLDLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEVL
                     VSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLERIAPVHIDTESISALIKQ
                     VNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDE
                     KVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSK
                     ETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLL
                     MNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTSTLRLLTT
                     ILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDE
                     CYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREY
                     LKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMA
                     KNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESP
                     KDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQ
                     TKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDS
                     DLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQ
                     QWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
                     PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRVGRSKQAATKENDSSEEVDVFQ
                     GSSPVDDIPQEETEEEEVSTVNVRRRSAKRERR"
ORIGIN      
        1 gccattttga agcggagagg aggaggaacg gcagggctgg ctgcggaagg ggaggggggg
       61 ggagaaggcg attggatgcg gcggcggcgg cggatcccgg agagccccgg agtgagcgga
      121 gtagcgagtc ggcaacccgg aggggtagaa atatttctgt catggctcat tcaaagacta
      181 ggaccaatga tggaaaaatt acatatccgc ctggggtcaa ggaaatatca gataaaatat
      241 ctaaagagga gatggtgaga cgattaaaga tggttgtgaa aacttttatg gatatggacc
      301 aggactctga agaagaaaag gagctttatt taaacctagc tttacatctt gcttcagatt
      361 tttttctcaa gcatcctgat aaagatgttc gcttactggt agcctgctgc cttgctgata
      421 ttttcaggat ttatgctcct gaagctcctt acacatcccc tgataaacta aaggatatat
      481 ttatgtttat aacaagacag ttgaaggggc tagaggatac aaagagccca caattcaata
      541 ggtattttta tttacttgag aacattgctt gggtcaagtc atataacata tgctttgagt
      601 tagaagatag caatgaaatt ttcacccagc tatacagaac cttattttca gttataaaca
      661 atggccacaa tcagaaagtc catatgcaca tggtagacct tatgagctct attatttgtg
      721 aaggtgatac agtgtctcag gagcttttgg atacggtttt agtaaatctg gtacctgctc
      781 ataagaattt aaacaagcaa gcatatgatt tggcaaaggc tttactgaag aggacagctc
      841 aagctattga gccatatatt accaattttt ttaatcaggt tctgatgctt gggaaaacat
      901 ctatcagcga tttgtcagag catgtctttg acttaatttt ggagctctac aatattgata
      961 gtcatttgct gctctctgtt ttaccccagc ttgaatttaa attaaagagc aatgataatg
     1021 aggagcgcct acaagttgtt aaactactgg caaaaatgtt tggggcaaag gattcagaat
     1081 tggcttctca aaacaagcca ctttggcagt gctacttggg caggtttaat gatatccatg
     1141 taccaatccg cctggaatgt gtgaaatttg ctagccattg tctcatgaac catcctgatt
     1201 tagcaaaaga cttaacagag tatcttaaag tgaggtcaca tgaccctgag gaagctatta
     1261 gacatgatgt tattgtgtca atagttacag ctgctaaaaa ggatattctt ctggtcaatg
     1321 atcacttact taattttgtg agagagagaa cattagacaa acgatggaga gtacgcaaag
     1381 aagccatgat gggacttgcc caaatttata agaaatatgc tttacagtca gcagctggaa
     1441 aagatgctgc aaaacagata gcatggatca aagacaaatt gctacatata tattatcaaa
     1501 atagtattga tgatcgacta cttgttgaac ggatctttgc tcaatacatg gttcctcaca
     1561 atttagaaac tacagaacgg atgaaatgct tatattactt gtatgccaca ctggatttaa
     1621 atgctgtgaa agcattgaat gaaatgtgga aatgtcaaaa tctgctccga catcaagtaa
     1681 aggatttgct tgacttgatt aagcaaccca aaacagatgc cagtgtcaag gccatatttt
     1741 caaaagtgat ggttattaca agaaatttac ctgatcctgg taaggctcag gatttcatga
     1801 agaaattcac acaggtgtta gaagatgatg agaaaataag aaagcagtta gaagtacttg
     1861 ttagtccaac atgctcctgc aagcaggctg aaggttgtgt gcgtgaaata actaagaagt
     1921 tgggcaaccc caaacagcct acaaatcctt tcctggaaat gatcaagttt ctcttggaga
     1981 ggatagcacc tgtgcacata gataccgaat ctatcagtgc tcttattaaa caagtgaaca
     2041 aatcaataga tggaacagca gatgatgaag atgagggtgt tccaactgat caagccatca
     2101 gagcaggtct tgaactgctt aaggtactct catttacaca tcccatctca tttcattctg
     2161 ctgaaacatt tgaatcatta ctggcttgtc tgaaaatgga tgatgaaaaa gtagcagaag
     2221 ctgcactaca aattttcaaa aacacaggaa gcaaaattga agaggatttt ccacacatca
     2281 gatcagcctt gcttcctgtt ttacatcaca aatctaaaaa aggacccccc cgtcaagcca
     2341 aatatgccat tcattgtatc catgcgatat tttctagtaa agagacccag tttgcacaga
     2401 tatttgagcc tctgcataag agcctagatc caagcaacct ggaacatctc ataacaccat
     2461 tggttactat tggtcatatt gctctccttg cacctgatca atttgctgct cctttgaaat
     2521 ctttggtagc tactttcatt gtgaaagatc ttctcatgaa tgatcggctt ccagggaaaa
     2581 agacaactaa actttgggtt ccagatgaag aagtatctcc tgagacaatg gtcaaaattc
     2641 aggctattaa aatgatggtt cgatggctac ttggaatgaa aaataatcac agtaaatcag
     2701 gaacttctac cttaagattg ctaacaacaa tattgcatag tgatggagac ttgacagaac
     2761 aggggaaaat tagtaaacca gatatgtcac gtctgagact tgctgctggg agtgctattg
     2821 tgaagctggc acaagaaccc tgttaccatg aaatcatcac attagaacaa tatcagctat
     2881 gtgcattagc tatcaacgat gaatgctatc aagtaagaca agtgtttgcc cagaaacttc
     2941 acaaaggcct ttcccgttta cggcttccac ttgagtatat ggcaatctgt gccctttgtg
     3001 caaaagatcc tgtaaaggag agaagagctc atgctaggca atgtttggtg aaaaatataa
     3061 atgtaaggcg ggagtatctg aagcagcatg cagctgttag tgaaaaatta ttgtctcttc
     3121 taccagagta tgttgttcca tatacaattc accttttggc acatgaccca gattatgtca
     3181 aagtacagga tattgaacaa cttaaagatg ttaaagaatg tctttggttt gttctggaaa
     3241 tattaatggc taaaaatgaa aataacagtc acgcttttat cagaaagatg gtagaaaata
     3301 ttaaacaaac aaaagatgcc caaggaccag atgatgcaaa aatgaatgaa aaactgtaca
     3361 ctgtgtgtga tgttgccatg aatatcatca tgtcaaagag tactacatac agtttggaat
     3421 ctcctaaaga cccggtacta ccagctcgtt tcttcactca acctgacaag aatttcagta
     3481 acaccaaaaa ttatctgcct cctgaaatga aatcattttt cactcctgga aaacctaaaa
     3541 caaccaatgt tctaggagct gttaacaagc cactttcatc agcaggcaag caatctcaga
     3601 ccaaatcatc acgaatggaa actgtaagca atgcaagcag cagctcaaat ccaagctctc
     3661 ctggaagaat aaaggggagg cttgatagtt ctgaaatgga tcacagtgaa aatgaagatt
     3721 acacaatgtc ttcacctttg ccggggaaaa aaagtgacaa gagagacgac tctgatcttg
     3781 taaggtctga attggagaag cctagaggca ggaaaaaaac gcccgtcaca gaacaggagg
     3841 agaaattagg tatggatgac ttgactaagt tggtacagga acagaaacct aaaggcagtc
     3901 agcgaagtcg gaaaagaggc catacggctt cagaatctga tgaacagcag tggcctgagg
     3961 aaaagaggct caaagaagat atattagaaa atgaagatga acagaatagt ccgccaaaaa
     4021 agggtaaaag aggccgacca ccaaaacctc ttggtggagg tacaccaaaa gaagagccaa
     4081 caatgaaaac ttctaaaaaa ggaagcaaaa aaaaatctgg acctccagca ccagaggagg
     4141 aggaagaaga agaaagacaa agtggaaata cggaacagaa gtccaaaagc aaacagcacc
     4201 gagtgtcaag gagagcacag cagagccgtg taggacgctc caaacaagca gctactaagg
     4261 aaaatgattc aagtgaagaa gtagatgtgt ttcagggtag ctctcctgtc gatgatattc
     4321 cacaggaaga aacagaggag gaggaagttt ctacagtaaa tgtacggcgg cgaagtgcta
     4381 aaagggaacg gcgatgaaca aatgtaatta ataactttct ctgtgaaagc tttggaaaaa
     4441 tctttttttt tttttttggt caagcttgag gctgaataaa gcctttgatg cacaaaatgg
     4501 gactgctgaa gagtggacag ttggacctta ctttggtgac cccatacatt tgtggtcaca
     4561 tgctttagcc atacacatgg taacattgac tatggagtct tgtgaaagtg taatgtgcga
     4621 tggctatgta gacataaaga agaaacttgt aaatatcttt tttctttttt ttaatgtttc
     4681 tgatttctga agtgcttgta tagcttttat ctgcggcttt aaactgacag tacccgactg
     4741 tttattggat ctattgattt gaaaagaatt tgttaggata gatcttaagc agtaatctgt
     4801 cagtgtttgt atttgtattc tctgcaattt tactgtgaaa aaaaatttgt tttcaacaat
     4861 tggtgtcatt ttcttgatgt cactatttgt tggagagtta aatggtctct tccctttgtg
     4921 tatcttacct agtgtttact cctgggcacc cttaatcttc agaggtgcta aattgtctgc
     4981 cattacacca gaaggatgcc tctgatagga ggacaaccat gcaaattgtg aaatagtcct
     5041 gaagttcttg gattacttta cacctcagta ttgatttgtc ccagaatttt ctggcctttc
     5101 atggcaatga aaattttaag aagaaagatt taaagtattt taattttaaa gagtgtgtta
     5161 taaaataatg tactgaattc tttatcccat tttatcatcc tttcagtttt tattaatcta
     5221 ctgtatcaat aaaattctgt aatttgaatg agtttttaat agtctagaat gttattgtgt
     5281 atagatattt cctcttgaac gttatgttca gaaaatgcaa attacactat aatataaaac
     5341 ctgatatata cacattagaa atattccagt tctccgtaac agtgtaaagt taatcagaaa
     5401 gaaaaaattt tattgatgca gtgtgtcttt ataaagctgt tcttgaaagc caagtgtttt
     5461 gtattttata gtgagttgca tgtttttgaa aaaaagtgct gaaaatggga tgtgctgttt
     5521 tctgtaaatt catatttagc catagtatat gatagattgc cccataacat agtttttcat
     5581 caagagttta ttattgtact ttattttgga gccaaaaaat tgattctggg gggtgggggc
     5641 agcgtagaag tggtatatcc aagtatatca gctactgtag ttgtcacagt cttgtgaact
     5701 ttgaatgaaa ttccactttg tccagattgg gagaagtgga aatttatttg gatttagagc
     5761 aggtcttttt ttttcttcat tgtaatctgc aaaatgtaga aataaattac ttaaggcagt
     5821 atcctttata cagttgtata aactgtattt tgaaccaaaa catataggtt actacttaat
     5881 gcttacctaa tttcatttta gtattttagg tgctgttatg ttttttcatg gttaacacca
     5941 gaggggaaaa aatcatattc taacttatta aatttatcac attgaatagt ggaacatttt
     6001 catatgatac accattatgt ttaagatata tttccaagat tggttataat agatggggca
     6061 tataataaag aagctactat tttggaaaat gacattttac tatttgccaa tgtatattgc
     6121 aattgatgtg attatttttc ttttaaagat ttgtttgtgt ttatgaaaca gccatttatt
     6181 ttttaaaaag tgttttgaat tgtgtcttaa tctctccata ttcaactatt cttcatttac
     6241 aacaatagtg acaccagtaa ttatgagagg ctgtcatata tcaaagcagc tcaggtggga
     6301 tcaacataca ttggttttga aatgtttcct tagctcggtt ctcccaaaca cataatttct
     6361 gtttcagcag tacaaaggca tgttttaaaa tctataacat aaagaataag gaatagcttt
     6421 gtatttttgt cattgattaa attgcaccag aaatgtttat ggaaatatta agaacatttt
     6481 ataaaacata cgaaaaagtg attgtgaagg atttttattt gcatgattat agttaagcaa
     6541 atttcatttc acatttttgt aatgctgtac agcagttcac aaaaaaatgt tcattgtaga
     6601 ttttgttatg ttcaatgcca atgagtctgt aattttacga cctgtctgtt ctttttttgg
     6661 gtggattacg atgtaaattt ttcttttctt tctttctttt tttttttttt tgtgtagaaa
     6721 aataggtgca ataatgatca aagttttgat gtcttgagtc tccatcttag gggattatct
     6781 tacgtttaag cttaacattt catgtagtaa gatttggaga gccacatact ttacagtaaa
     6841 attaagtgtg tataaaacat taattgctaa caattgttag caaactattt cagtgataat
     6901 gttcattttg aaaatatgta ctgtataaca ttaagaaaat atttaactcc ctgtaacaag
     6961 ttccattatg aaaatcttat tcctcagtga ggttatcttg ctgcactctg tagcaaattt
     7021 gtttaatcta cattataata aaatttcttg ctgcagtgca acaggaggct ttttcagtga
     7081 tcttcactgt atatgtaaat tacaaatgtg gctgtaaaac ttattccagg tattaaaggt
     7141 taaattgctt tctatatctt cttataactt gtaagtctga tttttaagat ttccttttgt
     7201 ccacttgtaa gaatgtcagg aatttaagaa tttgtttaaa ttaggcatat ctctgccatc
     7261 acatagtatt atgtcaccat aatgaacaat tgctatttaa atagataacc aattttcaga
     7321 cacatttttg gatttctgtg aagttgaata aacataaaag ctaa
//
