LOCUS       XM_047421904            4248 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens pyruvate dehydrogenase phosphatase
            catalytic subunit 1 (PDP1), transcript variant X2, mRNA.
ACCESSION   XM_047421904
VERSION     XM_047421904.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4248
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..4248
                     /gene="PDP1"
                     /gene_synonym="PDH; PDP; PDPC; PDPC 1; PPM2A; PPM2C"
                     /note="pyruvate dehydrogenase phosphatase catalytic
                     subunit 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 mRNAs, 5 ESTs, 1718 long SRA
                     reads, 4 Proteins, and 98% coverage of the annotated
                     genomic feature by RNAseq alignments, including 3 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:54704"
                     /db_xref="HGNC:HGNC:9279"
                     /db_xref="MIM:605993"
     CDS             186..1853
                     /gene="PDP1"
                     /gene_synonym="PDH; PDP; PDPC; PDPC 1; PPM2A; PPM2C"
                     /codon_start=1
                     /product="pyruvate dehyrogenase phosphatase catalytic
                     subunit 1 isoform X2"
                     /protein_id="XP_047277860.1"
                     /db_xref="GeneID:54704"
                     /db_xref="HGNC:HGNC:9279"
                     /db_xref="MIM:605993"
                     /translation="MFERIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACY
                     CHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQ
                     VNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGV
                     FDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYF
                     SKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNS
                     FLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNA
                     QNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPD
                     QLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRI
                     VGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNN
                     EFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE"
ORIGIN      
        1 gcagtccatg ggcttcgcgc cccggctgga tggaggggct ggccctcggg gcgcacccct
       61 gctcgcgcct gggccccgct gccttgggct gtggctttgc ctccccggcg gggagaatgt
      121 gtgtgtgtcc cgggcccaga cgaattgaat ttttgccttg aaggaaaaat gtagtggaga
      181 atttgatgtt tgaacgaatc ccagtcagaa gttccagcct gccactgttc tctgatgcca
      241 tgccagcacc aactcaactg ttttttcctc tcatccgtaa ctgtgaactg agcaggatct
      301 atggcactgc atgttactgc caccacaaac atctctgttg ttcctcatcg tacattcctc
      361 agagtcgact gagatacaca cctcatccag catatgctac cttttgcagg ccaaaggaga
      421 actggtggca gtacacccaa ggaaggagat atgcttccac accacagaaa ttttacctca
      481 cacctccaca agtcaatagc atccttaaag ctaatgaata cagtttcaaa gtgccagaat
      541 ttgacggcaa aaatgtcagt tctatccttg gatttgacag caatcagctg cctgcaaatg
      601 cacccattga ggaccggaga agtgcagcaa cctgcttgca gaccagaggg atgcttttgg
      661 gggtttttga tggccatgca ggttgtgctt gttcccaggc agtcagtgaa agactctttt
      721 attatattgc tgtctctttg ttaccccatg agactttgct agagattgaa aatgcagtgg
      781 agagcggccg ggcactgcta cccattctcc agtggcacaa gcaccccaat gattacttta
      841 gtaaggaggc atccaaattg tactttaaca gcttgaggac ttactggcaa gagcttatag
      901 acctcaacac tggtgagtcg actgatattg atgttaagga ggctctaatt aatgccttca
      961 agaggcttga taatgacatc tccttggagg cgcaagttgg tgatcctaat tcttttctca
     1021 actacctggt gcttcgagtg gcattttctg gagccactgc ttgtgtggcc catgtggatg
     1081 gtgttgacct tcatgtggcc aatactggcg atagcagagc catgctgggt gtgcaggaag
     1141 aggacggctc atggtcagca gtcacgctgt ctaatgacca caatgctcaa aatgaaagag
     1201 aactagaacg gctgaaattg gaacatccaa agagtgaggc caagagtgtc gtgaaacagg
     1261 atcggctgct tggcttgctg atgccattta gggcatttgg agatgtaaag ttcaaatgga
     1321 gcattgacct tcaaaagaga gtgatagaat ctggcccaga ccagttgaat gacaatgaat
     1381 ataccaagtt tattcctcct aattatcaca cacctcctta tctcactgct gagccagagg
     1441 taacttacca ccgattaagg ccacaggata agtttctggt gttggctact gatgggttgt
     1501 gggagactat gcataggcag gatgtggtta ggattgtggg tgagtaccta actggcatgc
     1561 atcaccaaca gccaatagct gttggtggct acaaggtgac tctgggacag atgcatggcc
     1621 ttttaacaga aaggagaacc aaaatgtcct cggtatttga ggatcagaac gcagcaaccc
     1681 atctcattcg ccacgctgtg ggcaacaacg agtttgggac tgttgatcat gagcgcctct
     1741 ctaaaatgct tagtcttcct gaagagcttg ctcgaatgta cagagatgac attacaatca
     1801 ttgtagttca gttcaattct catgttgtag gggcgtatca aaaccaagaa tagtgagtgg
     1861 ctctttcact ggcaattctc aaatgatata catttaaagg gcagattttt taaaaagata
     1921 ctactataat aaacatttcc agttggtcat tctaagcatt tacccttttg atactctagc
     1981 tagtcaggta ctccaaattg actttgcagc agggtggcag ggtcaggaga gtctggtcct
     2041 gcctagctca gatttcatgg cacctgcact tgaagcaagt cacttcttta tcacaggtgt
     2101 cttgaaacat tagcttcttt taccaacctg agaaaattag gatgacctgg caaataagat
     2161 cttgaatagg ccaaaagcaa gtatcttgct gtgtgtagtc tcttggttaa agtgaagaaa
     2221 cagtactgtt cacacctttc ttcactgaga ttccagtgta catgagaaca tatatttatt
     2281 gcatgatttt ctagatacac agtctatgca ttattcatat acatttattt tagcctaaag
     2341 tggttttcaa atccagttct tcaagccata aatgaccaag atccaagcaa tctgaatttg
     2401 tttttgtgat tatttgactg gaatgcttct taagtggaat aactatactc cgttatccac
     2461 ccgatttcct aatgtaattg aaagattttc tattttgcca cacacttgga gacaataagg
     2521 gtttttagtt ttatctactc ttctattgaa gttaaagaaa gaaaaaaaga tttttttatt
     2581 tgtattaatg aaaagcttta gtttaaaata aggagatcca gaataaaaag aagagactga
     2641 tctcttcaat tattgtcatc tgtagccacc agcacatcac tcttatgtaa tccccaaagg
     2701 cttggcatgc cgtaagtgtg tggtgggtag actgctgccg gggaatcgta cttcttattt
     2761 agtaatgata agacttttca ttatttttgg aattttaaag atgacataaa taagtttaaa
     2821 tatcaatttg gggagtaagg tttaatattg ccatcgggta ttgagacagg aggaagtttc
     2881 tgtttttctc catttagaca taggtcaatt aaaatatttg ggtttaaaat gactaaatgc
     2941 tttaaacata ttgtagctta agatatatgt gttaagatat atacatgaga aactttaaaa
     3001 ggtaactact gtgcatgcct gatgcttaat agaatactta gtggcatcaa atgtttgcag
     3061 cagtctccat aattatattc agtcccttct aatactgtat caatgtaaat gaaataaata
     3121 tattcaaatt ggctttttga tatgcatcaa gtggcatttt gttcctgtgt ttaatagtga
     3181 tctgtataca gctgtgcaca tattgtcatc acttattcta gcatcactgt taaggctgtg
     3241 attatgtttg atattcacct ggattttaat acaagccaat atcagcttcc cattgtgtaa
     3301 taacttgggt gtttaggagt cttttcacat tttttgggga tatgaactag atgttcaaga
     3361 actccttctg gactgtggat actgaatcag tgtactattg gctgcagaat ttgtttcaat
     3421 tgaaaataga ctcaggaaga ttgctgctca gaatatcata taatgtttat tttttgaggt
     3481 gtttttgttt ttatttgtgt gttttttttt ttttaagtca gcttggaact tttttcctgg
     3541 gtagtatttg ggagagggaa aggctgtact atatatttat ttctaaatgt tttgactggg
     3601 catttttctt ttaatgaaat atgtggactg ctctagcaaa ccctattttc agctactatt
     3661 tgaatattct tgaacaccac cactgaagag tttcatatac accaaataat gtctcatctc
     3721 tatagtacag ggaatataaa attggtttcc tgtggtcatg atcaagatag tagtattatt
     3781 acacaagaaa cttggtctgc agtctggaag cttgtctgct ctatagaaat gaaaatgcag
     3841 catgaagttg acattgtgga aatgaaagta attgggtatt agaaatctga aagtactgtc
     3901 atctaaaagc aattgtgatt ttattgtaat tggttgtcac tgttgtacgg tgtctagaat
     3961 taaagaatac atgtaaactt tcatggtatt tagcctttct taaatttttt taaaatttaa
     4021 actttctaac ctatgtattc aacttctgta tttatattta atcagtggtt catgttatat
     4081 aatacaccct taactagtta aatggaatgt tggtatggta cagagtacca tattgctaag
     4141 aaaactgtct tataaaagat gtatatgtgt gaagacatga aagtttaatg tacagaatgg
     4201 ttggagaaat gcctatggtg aattaaagct tcatatctgc tttctgaa
//
