LOCUS       XM_047438915            3887 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens phosphodiesterase 4A (PDE4A), transcript
            variant X8, mRNA.
ACCESSION   XM_047438915
VERSION     XM_047438915.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3887
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..3887
                     /gene="PDE4A"
                     /gene_synonym="DPDE2; PDE4; PDE46"
                     /note="phosphodiesterase 4A; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 13 ESTs, 301 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 35 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5141"
                     /db_xref="HGNC:HGNC:8780"
                     /db_xref="MIM:600126"
     CDS             129..1877
                     /gene="PDE4A"
                     /gene_synonym="DPDE2; PDE4; PDE46"
                     /codon_start=1
                     /product="3',5'-cyclic-AMP phosphodiesterase 4A isoform
                     X8"
                     /protein_id="XP_047294871.1"
                     /db_xref="GeneID:5141"
                     /db_xref="HGNC:HGNC:8780"
                     /db_xref="MIM:600126"
                     /translation="MKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLN
                     NSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLK
                     KFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEIL
                     AALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIF
                     QNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRI
                     QVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASV
                     EKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESR
                     GPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEA
                     SPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPS
                     ALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDT
                     SALPAPGGGGSGGDPT"
ORIGIN      
        1 ccaccacctc ctggaagatt tcccacatcc cctctggttt cctgactctg agtagccagc
       61 ggcatcacag ctgaaagggt tctgccgttt cggacaaaca gaatgaagtg gagatcccat
      121 cacccacgat gaaggaacga gaaaaacagc aagcgccgcg accaagaccc tcccagccgc
      181 ccccgccccc tgtaccacac ttacagccca tgtcccaaat cacagggttg aaaaagttga
      241 tgcatagtaa cagcctgaac aactctaaca ttccccgatt tggggtgaag accgatcaag
      301 aagagctcct ggcccaagaa ctggagaacc tgaacaagtg gggcctgaac atcttttgcg
      361 tgtcggatta cgctggaggc cgctcactca cctgcatcat gtacatgata ttccaggagc
      421 gggacctgct gaagaaattc cgcatccctg tggacacgat ggtgacatac atgctgacgc
      481 tggaggatca ctaccacgct gacgtggcct accataacag cctgcacgca gctgacgtgc
      541 tgcagtccac ccacgtactg ctggccacgc ctgcactaga tgcagtgttc acggacctgg
      601 agattctcgc cgccctcttc gcggctgcca tccacgatgt ggatcaccct ggggtctcca
      661 accagttcct catcaacacc aattcggagc tggcgctcat gtacaacgat gagtcggtgc
      721 tcgagaatca ccacctggcc gtgggcttca agctgctgca ggaggacaac tgcgacatct
      781 tccagaacct cagcaagcgc cagcggcaga gcctacgcaa gatggtcatc gacatggtgc
      841 tggccacgga catgtccaag cacatgaccc tcctggctga cctgaagacc atggtggaga
      901 ccaagaaagt gaccagctca ggggtcctcc tgctagataa ctactccgac cgcatccagg
      961 tcctccggaa catggtgcac tgtgccgacc tcagcaaccc caccaagccg ctggagctgt
     1021 accgccagtg gacagaccgc atcatggccg agttcttcca gcagggtgac cgagagcgcg
     1081 agcgtggcat ggaaatcagc cccatgtgtg acaagcacac tgcctccgtg gagaagtctc
     1141 aggtgggttt tattgactac attgtgcacc cattgtggga gacctgggcg gaccttgtcc
     1201 acccagatgc ccaggagatc ttggacactt tggaggacaa ccgggactgg tactacagcg
     1261 ccatccggca gagcccatct ccgccacccg aggaggagtc aagggggcca ggccacccac
     1321 ccctgcctga caagttccag tttgagctga cgctggagga ggaagaggag gaagaaatat
     1381 caatggccca gataccgtgc acagcccaag aggcattgac tgcgcaggga ttgtcaggag
     1441 tcgaggaagc tctggatgca accatagcct gggaggcatc cccggcccag gagtcgttgg
     1501 aagttatggc acaggaagca tccctggagg ccgagctgga ggcagtgtat ttgacacagc
     1561 aggcacagtc cacaggcagt gcacctgtgg ctccggatga gttctcgtcc cgggaggaat
     1621 tcgtggttgc tgtaagccac agcagcccct ctgccctggc tcttcaaagc ccccttctcc
     1681 ctgcttggag gaccctgtct gtttcagagc atgccccggg cctcccgggc ctcccctcca
     1741 cggcggccga ggtggaggcc caacgagagc accaggctgc caagagggct tgcagtgcct
     1801 gcgcagggac atttggggag gacacatccg cactcccagc tcctggtggc ggggggtcag
     1861 gtggagaccc tacctgatcc ccagacctct gtccctgttc ccctccactc ctcccctcac
     1921 tcccctgctc ccccgaccac ctcctcctct gcctcaaaga ctcttgtcct cttgtccctc
     1981 ctgagaaaaa agaaaacgaa aagtggggtt tttttctgtt ttcttttttt cccctttccc
     2041 cctgccccca cccacggggc ctttttttgg aggtgggggc tggggaatga ggggctgagg
     2101 tcccggaagg gattttattt ttttgaattt taattgtaac atttttagaa aaagaacaaa
     2161 aaaagaaaaa aaaaagaaag aaacacagca actgtagatg ctcctgttcc tggttcccgc
     2221 tttccacttc caaatccctc ccctcacctt cccccactgc cccccaagtt ccaggctcag
     2281 tcttccagcc gcctggggag tctctacctg ggcccaagca ggtgtggggc ctccttctgg
     2341 gcttttcttc tgaatttaga ggatttctag aacgtggtca ggaatagcca ttctaggcgg
     2401 ggctggggcc agggtggggg gcagtcactg tgggaggtcc cagctccagc ccccctctgg
     2461 tttgctgcct cctctcccct ctaaaaaagt cttccgcttg attttgcaca atcccggcga
     2521 tactcctggc gatactgact agaaagtcag ggagctgggg gagctgttca ctttaggata
     2581 cgggggtggt atggaaggga gcgttcacac cgccagcctc gggcctggga tttgaggagg
     2641 gccctagacc tcctccactc tccatcccct ttcccttcca ctttgggttc actttgaatt
     2701 ttctccgttt tttggggcag tggctctgat ccactcaccc ccccgccccc cgccccactt
     2761 ctagctgctt ctcctcttgt ttctgcctta ataattccca cggccacagg caagggggtt
     2821 gcagtggccg cctgcacctt ggatgaggca gggccaggcg cccagaaccc ccatcctggc
     2881 cgcacccccc tttccagggt cctccggacc ccaccttcca cactctgatc acagcccccc
     2941 taccttttgc cctaggagga agcaataatg gtgtataccc tcattctcat tcctgggcag
     3001 cccttccttc caccctggca ccaaaataat ttctcctcca tccgtacctt gcctagcctc
     3061 tccctctccc ccagctagtc cctgagcaat acggcagaca gatgcaagac catttttctc
     3121 caagccatgg gggactgttt ggaaggaaag ccccctctct ccctcctccc ctcgccctcg
     3181 gcctggttct gcagctggac cgacctcatt catcgcctgc cccctaccca attctgagca
     3241 cacggtactg tagcccccag ttcctcccta gccttccatc cctctgtcca ccccaggggg
     3301 aggtaacccc gcactcacac tcccttgatg ctgtctgtac agggttcata ttttgtagcg
     3361 aaagtcgttt ttgtcccagc cggcgatcgg agtgggcctt ttctttcttt ttgttcattc
     3421 tttacctttt tttcttttct ttctttcttt tttgtacata ctgtaaggtt ggtttgtaaa
     3481 ttattctacg gaggcaaaaa gggaaaataa aaacttgccc ttccctggct gacccagtcg
     3541 ggaaggtagg gaaggaggtc tcccgttggg agagtctctg ttcctgctgt attatacaaa
     3601 ctgtaccata gtcctgggaa aagggtggac tcaccgctgt tgttttatgg gaagtcgtgt
     3661 catcctaggg gttggggctg ggcagagcct gtcccctccc cccttctcca ggagccaggg
     3721 ggtgactgga gagacagacc cacccccaag cagggctcct ctccccaggg tgagcacagg
     3781 acctctgtaa gctgcttgtg tattgtccac tttgacgatc agtcattcgg tccgttgatc
     3841 aataatcctt cgatcttgtc tccaattaaa ccgaggcttt caccgat
//
