LOCUS       NM_001330177           18069 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens pecanex 4 (PCNX4), transcript variant 1, mRNA.
ACCESSION   NM_001330177 XM_005268009
VERSION     NM_001330177.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 18069)
  AUTHORS   Andreev,D.E., O'Connor,P.B., Fahey,C., Kenny,E.M., Terenin,I.M.,
            Dmitriev,S.E., Cormican,P., Morris,D.W., Shatsky,I.N. and
            Baranov,P.V.
  TITLE     Translation of 5' leaders is pervasive in genes resistant to eIF2
            repression
  JOURNAL   Elife 4, e03971 (2015)
   PUBMED   25621764
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18069)
  AUTHORS   Huang,Y.P., Cheng,J., Zhang,S.L., Wang,L., Guo,J., Liu,Y., Yang,Y.,
            Zhang,L.Y., Bai,G.Q., Gao,X.S., Ji,D., Lin,S.M. and Shao,Q.
  TITLE     Screening of hepatocyte proteins binding to F protein of hepatitis
            C virus by yeast two-hybrid system
  JOURNAL   World J Gastroenterol 11 (36), 5659-5665 (2005)
   PUBMED   16237761
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL157911.4, AL163853.4 and AA651916.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001330177.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.246261.1,
                                           SRR1660809.161873.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000406854.6/ ENSP00000384801.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-497               AL157911.4         151148-151644
            498-1239            AL157911.4         166811-167552
            1240-1419           AL157911.4         173925-174104
            1420-1782           AL157911.4         174199-174561
            1783-1907           AL163853.4         84112-84236
            1908-2008           AL163853.4         84494-84594
            2009-2128           AL163853.4         84716-84835
            2129-2492           AL163853.4         87104-87467
            2493-2596           AL163853.4         89971-90074
            2597-3630           AL163853.4         92993-94026
            3631-3817           AL163853.4         94412-94598
            3818-4573           AL163853.4         102745-103500
            4574-4662           AA651916.1         21-109              c
            4663-18069          AL163853.4         103590-116996
FEATURES             Location/Qualifiers
     source          1..18069
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q23.1"
     gene            1..18069
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /note="pecanex 4"
                     /db_xref="GeneID:64430"
                     /db_xref="HGNC:HGNC:20349"
     exon            1..497
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            498..1239
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     CDS             551..4069
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     hepatitis C virus F protein-binding protein 2;
                     pecanex-like protein 4; HCV F-interacting protein;
                     pecanex-like protein C14orf135; HCV F protein-binding
                     protein 2; pecanex-like 4; pecanex homolog protein 4;
                     pecanex homolog 4"
                     /codon_start=1
                     /product="pecanex-like protein 4 isoform 1"
                     /protein_id="NP_001317106.1"
                     /db_xref="CCDS:CCDS81809.1"
                     /db_xref="GeneID:64430"
                     /db_xref="HGNC:HGNC:20349"
                     /translation="MSPDVPLLNDYKQDFFLKRFPQTVLGGPRFKLGYCAPPYIYVNQ
                     IILFLMPWVWGGVGTLLYQLGILKDYYTAALSGGLMLFTAFVIQFTSLYAKNKSTTVE
                     RILTTDILAEEDEHEFTSCTGAETVKFLIPGKKYVANTVFHSILAGLACGLGTWYLLP
                     NRITLLYGSTGGTALLFFFGWMTLCIAEYSLIVNTATETATFQTQDTYEIIPLMRPLY
                     IFFFVSVDLAHRFVVNMPALEHMNQILHILFVFLPFLWALGTLPPPDALLLWAMEQVL
                     EFGLGGSSMSTHLRLLVMFIMSAGTAIASYFIPSTVGVVLFMTGFGFLLSLNLSDMGH
                     KIGTKSKDLPSGPEKHFSWKECLFYIIILVLALLETSLLHHFAGFSQISKSNSQAIVG
                     YGLMILLIILWILREIQSVYIIGIFRNPFYPKDVQTVTVFFEKQTRLMKIGIVRRILL
                     TLVSPFAMIAFLSLDSSLQGLHSVSVCIGFTRAFRMVWQNTENALLETVIVSTVHLIS
                     STDIWWNRSLDTGLRLLLVGIIRDRLIQFISKLQFAVTVLLTSWTEKKQRRKTTATLC
                     ILNIVFSPFVLVIIVFSTLLSSPLLPLFTLPVFLVGFPRPIQSWPGAAGTTACVCADT
                     VYYYQMVPRLTAVLQTAMAAGSLGLLLPGSHYLGRFQDRLMWIMILECGYTYCSINIK
                     GLELQETSCHTAEARRVDEVFEDAFEQEYTRVCSLNEHFGNVLTPCTVLPVKLYSDAR
                     NVLSGIIDSHENLKEFKGDLIKVLVWILVQYCSKRPGMKENVHNTENKGKAPLMLPAL
                     NTLPPPKSPEDIDSLNSETFNDWSDDNIFDDEPTIKKVIEEKHQLKDLPGTNLFIPGS
                     VESQRVGDHSTGTVPENDLYKAVLLGYPAVDKGKQEDMPYIPLMEFSCSHSHLVCLPA
                     EWRTSCMPSSKMKEMSSLFPEDWYQFVLRQLECYHSEEKASNVLEEIAKDKVLKDFYV
                     HTVMTCYFSLFGIDNMAPSPGHILRVYGGVLPWSVALDWLTEKPELFQLALKAFRYTL
                     KLMIDKASLGPIEDFRELIKYLEEYERDWYIGLVSDEKWKEAILQEKPYLFSLGYDSN
                     MGIYTGRVLSLQELLIQVGKLNPEAVRGQWANLSWELLYATNDDEERYSIQAHPLLLR
                     NLTVQAAEPPLGYPIYSSKPLHIHLY"
     exon            1240..1419
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1907
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            1908..2008
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            2009..2128
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2492
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            2493..2596
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            2597..3630
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            3631..3817
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     exon            3818..18069
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4634..4639
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /note="hexamer: AATAAA"
     polyA_site      4660
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /note="major polyA site"
     regulatory      13217..13222
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /note="hexamer: AATAAT"
     polyA_site      13241
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
     polyA_site      14714
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
     regulatory      18049..18054
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
                     /note="hexamer: AATAAA"
     polyA_site      18069
                     /gene="PCNX4"
                     /gene_synonym="C14orf135; FBP2; PCNXL4"
ORIGIN      
        1 gcgtaaaggc ccggcccaag ggaacgttca gggcgtctcg gctttccccg ctgctgcttc
       61 tgctaggccc agtgcgagac cagagcacga gcgactcccg tcgtccccgg ccaggcagat
      121 gttggcctag tcctggcgcg aacgaagcgc gctatttccc tgcttcctct aggccaagcc
      181 tgctttacgg cagggcccgc ctcgggagcg agcacagacc ggggcagcga ggccagccag
      241 gcgccgacga ggtccccgaa cgcgcacgcg ctccgttcag ctccgggtgg cggccgccgg
      301 agtagacgtt agccatggaa accgagagct ggcccgggcg gggccgcggt gagctcgtta
      361 ttcggccgcc gcagcttttc tgcctccgca ttcgggcact aaccaacctc ccggcgggag
      421 cgcccagccc gagtttacct gcaaaaatgc ggtccctggg atgccttcgc gtcttctctt
      481 ccctcgggtg acttgagaaa ctgctgtgtt acagaaaagc atgtgacttt cagaataatc
      541 ccgagtgagg atgagtccag atgtgcctct actgaatgat tacaagcagg acttctttct
      601 gaagcgcttt ccacagactg ttcttggagg ccctcgattc aaattaggct attgtgcccc
      661 tccttacata tatgttaatc aaattattct ttttctaatg ccatgggttt ggggtggagt
      721 cggaacactt ttataccagt taggcatcct gaaagactat tatacagcag cactttcagg
      781 tggattaatg ctttttactg catttgtcat ccagttcaca agtttatacg ccaaaaacaa
      841 atcaacaaca gtagaaagaa tactaaccac ggatatctta gcagaggagg atgagcatga
      901 atttaccagt tgtactggtg ctgagactgt caaatttctc attcctggca agaaatatgt
      961 agccaataca gtttttcatt ctattcttgc tggattagcg tgtggtcttg gaacatggta
     1021 tctgctccca aatagaataa ccttgctgta tggcagtaca ggaggcactg ctctactatt
     1081 cttctttgga tggatgacac tatgtatagc agaatattct ttaattgtaa acacagctac
     1141 agagactgcg actttccaaa cacaggatac ttatgaaatt attcctctta tgagacctct
     1201 ttatattttt ttctttgttt ctgtggatct ggcacacagg tttgtggtaa atatgccagc
     1261 tctagaacac atgaatcaga ttttacacat cttgtttgta tttttaccct ttctgtgggc
     1321 acttgggact ctgcccccac ccgatgcact tctcttatgg gcaatggagc aggttttaga
     1381 gttcggcctt ggaggctcat ctatgtcaac ccacttacgg ttattagtaa tgttcatcat
     1441 gtctgctgga acagctatag catcatattt cattccaagc actgttggtg tggttctttt
     1501 catgactgga tttggtttct tgctgagtct gaacttaagt gatatgggtc acaaaattgg
     1561 aaccaaatct aaggatttac ccagtggtcc ggaaaaacat ttttcatgga aggaatgcct
     1621 tttctacatc attatattag tcttggctct tttagaaact agcttgcttc atcactttgc
     1681 tggcttctca cagatttcta aaagcaattc ccaggctatt gtgggctatg gtttgatgat
     1741 attacttata atactgtgga tacttagaga aattcaaagc gtatatatca ttggaatttt
     1801 ccgaaatccc ttttatccga aggatgtgca aactgtgact gtattctttg agaagcaaac
     1861 taggctcatg aagattggta ttgtcagacg gattttgcta actttagtat caccttttgc
     1921 catgatagca tttctttcat tggacagttc cttacaaggg ctccactcag tgtctgtctg
     1981 tattggattc acaagagcct ttagaatggt atggcagaat acagaaaatg ctttattgga
     2041 gacagtcatt gtatcaacag tacacttgat ctccagtaca gacatatggt ggaacagaag
     2101 cctggataca ggactcagac tcttactggt tggtatcata cgtgatcgtt tgattcagtt
     2161 catctctaaa ttgcagtttg ccgtgactgt gcttttgaca tcatggacag agaaaaaaca
     2221 acgtcgaaaa acaactgcca ctttatgtat actcaacatt gtcttttctc cattcgtgtt
     2281 ggtcatcata gttttttcta cactactctc ttctccctta ctccctcttt tcacccttcc
     2341 tgtgttcttg gtggggtttc cccgacctat tcagagttgg ccaggagcag caggcaccac
     2401 agcctgtgtg tgtgcagata cagtgtacta ctaccaaatg gtgcccaggt tgactgctgt
     2461 actgcagact gcaatggcag ctggaagttt aggtctcctc ctacctggat ctcattactt
     2521 gggccgtttt caggatcgtt taatgtggat aatgattctg gaatgtggct atacttactg
     2581 ctctattaac attaaggggt tagaattgca ggaaacatcc tgtcatactg cagaagctcg
     2641 cagagttgat gaagtttttg aagatgcttt tgagcaagaa tacacaagag tatgttccct
     2701 taatgaacac tttggaaatg tcttgacacc ctgtactgtt ttgcctgtga aattgtattc
     2761 tgatgccagg aatgttctat caggcataat tgattctcat gaaaacttaa aagaatttaa
     2821 aggtgacctc attaaagtac ttgtgtggat acttgttcaa tactgctcca aaaggcctgg
     2881 catgaaagag aatgttcaca acactgaaaa taaagggaaa gcacctctaa tgttgcctgc
     2941 tttgaacact ttgccacctc ccaaatcccc agaagacata gacagtttaa attcagaaac
     3001 ttttaatgac tggtctgatg ataatatttt tgatgatgag ccaactatca aaaaagtaat
     3061 agaagaaaaa catcagttga aagatttgcc aggtacaaat ttgtttattc caggatcagt
     3121 agaatcacag agggttggtg atcattctac aggcactgtt cctgaaaacg atctttacaa
     3181 agcagttcta ttaggatacc ctgctgttga caaaggaaaa caagaggaca tgccatatat
     3241 tcctctcatg gagttcagtt gttcacattc tcacttagta tgcttacccg cagagtggag
     3301 gactagctgt atgcccagtt ccaaaatgaa ggagatgagc tcgttatttc cagaagactg
     3361 gtaccaattt gttctaaggc agttggaatg ttatcattca gaagagaagg cctcaaatgt
     3421 actggaagaa attgccaagg acaaagtttt aaaagacttt tatgttcata cagtaatgac
     3481 ttgttatttt agtttatttg gaatagacaa tatggctcct agtcctggtc atatattgag
     3541 agtttacggt ggtgttttgc cttggtctgt tgctttggac tggctcacag aaaagccaga
     3601 actgtttcaa ctagcactga aagcattcag gtatactctg aaactaatga ttgataaagc
     3661 aagtttaggt ccaatagaag actttagaga actgattaag taccttgaag aatatgaacg
     3721 tgactggtac attggtttgg tatctgatga aaagtggaag gaagcaattt tacaagaaaa
     3781 gccatacttg ttttctctgg ggtatgattc taatatggga atttacactg ggagagtgct
     3841 tagccttcaa gaattattga tccaagtggg aaagttaaat cctgaagctg ttagaggtca
     3901 gtgggccaat ctttcatggg aattacttta tgccacaaac gatgatgaag aacgttatag
     3961 tatacaagct catccactac ttttaagaaa tcttacggta caagcagcag aacctcccct
     4021 gggatatccg atttattctt caaaacctct ccacatacat ttgtattaga gctcattttg
     4081 actgtaatgt catcaaatgc aatgttttta ttttttcatc ctaaaaaagt aactgtgatt
     4141 cttgtaactt gaggacttct ccacaccccc attcagatgc ctgagaacag ctaagctccg
     4201 taaagttggt tctcttagcc atcttaatgg ttctaaaaaa cagcaaaaac atctttatgt
     4261 ctaagataaa agaactattt ggccaatatt tgtgccctct ggactttagt aggctttggt
     4321 aaatgtgaga aaacttttgt agaattatca tataatgaat tttgtaatgc tttcttaaat
     4381 gtgttatagg tgaattgcca tacaaagtta acagctatgt aatttttaca tacttaagag
     4441 ataaacatat cagtgttcta agtagtgata atggatcctg ttgaaggtta acataatgtg
     4501 tatatatttg tttgaaatat aatttatagt attttcaaat gtgctgattt attttgacat
     4561 ctaatatctg aatgtttttg tatcaagtag tttgttttca tagacttcaa ttcataaact
     4621 ttaaaaaact tttaataaaa tattttcctt ccttttcaaa tatccttcta atatatgtga
     4681 aaggagcggg gttcatccca ttcatcatgt gaatattcac aggaagagca atgttagggt
     4741 aatctgcata tgactactaa agcatatatc tgactcatta tgtatttctt tcaactgaat
     4801 ttactgcttc tgaaaaatga tttacccaac aggactacca gttactagtg tcttaaggta
     4861 tatgaactaa agtcagaagg agatggaaga aaatttttat aatacgatct gaattttatt
     4921 ttcattctct tcttgcttag gaacgtttta cagatacatg taagggggat taataatgaa
     4981 tccacatcag ttgagagatc agtttcctct aattcttact taatttccaa tgaaatcagt
     5041 aggagccccc tagatttata ataatgtatt ctccttagaa atcattcaaa ttatatgaaa
     5101 tgtaccagtt aagttgttat tagtattcca tttatttagt atgtggacga gttcactcta
     5161 acaatgttaa aggataaact ttttggacca attttcagtt aatgaattca agagatttgt
     5221 atgttattct ttttttggag gtaatatagt acagttacta agataggatt ttgtattact
     5281 ctgagtttac atctcagact tatgatttaa tttacatgat tgagatttgc tagctgtaca
     5341 cctttatatc tttgtcatgt agaaatattt tctcatgtcg ttaaaagtac ttgtaattat
     5401 cagctttttt ttttttccga gatggaatct cgctctgtca cccaggctgg ggtgcagtgg
     5461 cacgatctca gctcactgca acctccgcct tctgggttca agcgattctc ctggctcagc
     5521 ctcctgagta gctgggatta aaggcgcatg ccaccacgcc ggctaatttt tgtattttta
     5581 gtagagacag agtttcacca tgttggccag gctggtctcg aactcttgac ctcatgctcc
     5641 gcccgcctca gcctcccaaa gtgctgggat tacaggcgtg agccaccgtg cccagccata
     5701 attatcactt ttaatgacag cataaaattc cattgataga tattatttat tggactactg
     5761 tcccccaaat aatgtgaatt ttaagttgtt tagagatttt cactgtgata ataatgtcaa
     5821 gctatgcctt cgcttaacct tgcatcctcc tcaaagtgct cccatatctc catttcattc
     5881 atagccaggt tttctctttc atttacttgt caaatcattc caatctggat cccatctcca
     5941 tgactctccc aaattaaaaa aaaaaaaagt ttttattaag gtcactattg acctttttat
     6001 tgtcaaacca gctagtagta attgacacat ttgaccattc cttgaagcag cttttgtgtt
     6061 ttcttttgaa ctttcctgac actacattat ctttgttttc ttcttatctt cctagcaact
     6121 cctcaaacat ctttgctgcc tctcctcttc tacctgacct ctaaatttta gaatttctca
     6181 acaattgatt ctaggccccc ctttgtgttt ctgcaatcac catagataat ctcatctact
     6241 tcaagacttg aaatatcatc aataaattga tgatgatcaa atatatgtac ctaacccaac
     6301 ctctcttctt acactgaacc tatatatatc acttatttgg tatcttcact tggtatatta
     6361 aaaactgact gttagatttt gaagggaagg tgagagttaa agaaagacac acagagggca
     6421 gcttgacagc aaatgcagac tttatgtcta gcataaaacc tacagaagtg ggggaccagc
     6481 ttaatgccag agcccaccgc tgcttacagg ctgggcgtac ttataggcat gggtgagagg
     6541 ggtctgggca gtatggcttg ctgctcggca ggatattgat aagatgctcc catgatgagg
     6601 tggttctggc ccttgttgtg gtgggatgtc atcatagtat tccttggaac tttgcccagc
     6661 aagatatgat agggatattt cttaggttgg gcctttttcc gccttgtggt caggtggtta
     6721 ggcagcatgt ttctcactgc ccgaacccct gtgaaatgtt ttactttgat caaggtctgc
     6781 aaaatagcgg ggagcttaca aaatggtgca gtttggacta acactaacgt tactgaattt
     6841 tccctaaaac ctacttttct acttctaact tttagtggtg cattcatacc aactatttca
     6901 gagaactagc aatgccaggc aaaatagtat tttaaaatct gcttaaaggc attagagaac
     6961 caaaagacag tgaagaataa catcactaag atctaagaca gaatgaaact tagagacctg
     7021 agctcagcat ttgggctgct tttcttatag gagacatgcc aattcaggat aaggtggttg
     7081 agagtctgag acgctaagta acacttataa cagccttgct gctgagttag agggacaaaa
     7141 actggagacc aagactctcc aaggaagtag gggaggggaa aggaatccta gttaactgac
     7201 catacattgg gttgtgaccc caaggaccat atccaaattg taagggtgaa gaaaaaccag
     7261 atgcagttag gatcttctca cttcccaaaa ctggattcag gtgacccttt gctgcagccg
     7321 ctacccagag caaatgtaaa tcctctctgg actgatcttt tgagttattt ttataacttt
     7381 tcatgtttag tgttggaaag ttatttaagg tatctgagga aacaagacaa catgatgaaa
     7441 atccgaaaga agcgacagat gatgggacag agccacaggg gacccagata atgagctata
     7501 caacacaggg tctaaaatta ctatgtttag tgtgtttaaa gatctaaaac acaagattga
     7561 gaatttcagc agaaaatcag aaactatata gaagaatcaa tcaacaagtc cccaacttaa
     7621 aagtacatta atcaagttta agaattcagt gaataggccg ggcgcggtgg ctcacgcctg
     7681 taatcccagc actttgggag gctgaggcgg gtggatcatg aggtcaggag atcgagacca
     7741 tcctggctaa cacaatgaaa ccccatctgt agtaaaaata aaaaaaaaaa taaccgggtg
     7801 tggtggtggg tgcctgtagt cccagctact caggaggctg aggcaggaga atcacttgaa
     7861 cccgggaggc agaggtttca gtgagccaag atcatgccac tgcactccag cctgggcgac
     7921 agagcgagac tccatctcaa aaagaaaaaa aaaaaaaaag gattcagtga atagatttga
     7981 tagaaagtgc atacagtgaa gtaagaatta gtgaactaga agttatgtca gaagtaaata
     8041 ccagatgtga aaaactaaga gacaaaagaa tagaaaatat agtagagagt ataagagaca
     8101 tagagttaac ttgagaagat ctaacataca cgtaactgga tttccaggag aagagagaat
     8161 atggcagaag caacctgtga ggagataatg actgagaatt ctccaagttt ttaagacatg
     8221 aagacctgca agatcaaagc atgataaata aaaacaaaat tacaacttag cacatcctaa
     8281 gaaaaaataa aacacaaaaa gaaaatcatt aaaggagcca gacaatgata aaagacatta
     8341 cttttaaagg aggcacaatt ttattaaact gacagctaac ttctcaacag aaaatatggg
     8401 aagcagaaat caatggcatg atattttcag gttactgaaa gaaaatatct gcaattttag
     8461 aattcaatac ccagcctttc cccaaaaaca attcttaaga atgaaggcaa agacactttc
     8521 aaacgcaaca aatttaatag cagattgtca ttaaaggtga tagtaaaggg tattcttcag
     8581 acagaaggaa aaagatccca gaaaaaggtt agagataaag gtaggaatga acagtaattt
     8641 aaaaatatat atatacagtt taagtgaata ttaactatat aaaatagtct tcgaggttaa
     8701 aataaataat gttaaaatgt gacaataata tacaaatttg gtgcaggaat tctaaggtca
     8761 gaattatcag aaagaagatt aaagtataaa taagactgct gtgtcatcta tagggtaacc
     8821 actaaaagaa cagcaaaaag caaaataaaa caatcgtaga actacaaagc taatacaggg
     8881 ctaaagtgga ataataaggc aaaaaggtag agaaaatata gaacaaatag gacaaataga
     8941 aatcaaacag tagattagga ggtttaaata tcagttacaa cattcatatg aatagacagt
     9001 gtaccaatta aatgcaaaga tcatcaaagt gaaaagaaag aaaacccaca aagtaccttt
     9061 atgcaagaga tgtcttaagt ataggaatac aaaggtttga agtaaacaag aatggaaaaa
     9121 ttataatatg aaatacaaaa aacaaaaacg atagggcagg ggactatggt ggctattgca
     9181 acattattca atgtagacct taaggtgaaa agtattacaa agagagacaa tttgtaatga
     9241 taaaagattt gattcaccag aaagtttcaa caggtctaat attttaatga tttaacaata
     9301 tagcctcaaa tatataagca gaaatgaaca gaactaaaat gagaaaagac aagtctgcat
     9361 tcccagattt taatatactc agtaacagaa cagcagccat gcaaaaatac gtaaatatgt
     9421 aaagattgga ataatacttt aaaacttaac ctaattggca tatatgaaac agaataccca
     9481 acaactgcaa aatacacatt attttcaaat gcagatagaa tatttatcaa aactgaccat
     9541 attccaagtc ataggaatgg aatatattct ttggccatgt atcattcact tagaaatcaa
     9601 taataatttc aaaaatagaa aaattctatt aagttcataa attaagaaat acacttttaa
     9661 ataactcatg gatcagacaa taaattacaa tgaaaattag aatatatttg aactgagtag
     9721 tgaaagtgct acatgtcaaa acttatggta gacgcctaaa gccatgctta gaaggaaatt
     9781 tatagtctta aacgcacatt aaaaaaaaaa gattgaaaat gaacctagta gttaaaatat
     9841 tctaagaata gcaaattaaa cctgaagaaa ataaaggaaa taataaagaa caagaattaa
     9901 tggagtagaa aatgaagata aagtggatca actaagccaa aagttgattc tttgaaaaga
     9961 taattgataa gtgtctggta gactgaaaaa ggaagaaaca caaacaacca atatcaggaa
    10021 tgaaaggata ttacaaatcc tagagtcatc tgacaaaata tgtgcacaac ttcatgccaa
    10081 ttagttggaa attttagatg aagtgaataa attctttaaa ctatggaaga gccaaaattg
    10141 acaaatgaaa aaatagaaaa ttcgagtagt tccctatctg ctaaagaagt ggaacctata
    10201 gttactttat ttgcttttcc atagtgaaac aacaagccta gatggattga ttcgtcaatg
    10261 gaaagacaat cttaaattct tacaaagagc agtagaaatg caggaaccct ccccaactca
    10321 ttttatgatg ccagaaaacc tagataccaa aacctggcaa aaactttatg agaaagggac
    10381 ctatttcatt ccccccaaca tcaatgcaaa aatcccaaac aaaatactag caaactaaac
    10441 tacacacata cacacacaca cacacacccc tacacacaca gaataatcac aatcaagttg
    10501 ggtttcttcc tgaaaaagtg aggttggtgt gatagttgca aatcaatcaa tatgattcaa
    10561 cacattaaca gaatgaaagg agaaaaataa tatttcagta gatccagaaa aagtatttga
    10621 taaaccagta tccactcata aaaagtttgc tttttaatat tcatctttat ttttcttatc
    10681 ttgagtatgc acataagatg ttcagagtca gagatagatt tcttattact cagggtaaac
    10741 aagtgcacct gcccaccttt gcactcgtcc atatccccca gagcaacctg ataagaaact
    10801 catgggattt tggctatgta agtggccaaa tactgcatag gcaagggaca gggaaaatta
    10861 attttcccta cttataaaga tgaaagaggc agccatcctc ttcccttcct gaaagagtct
    10921 gcttttactc tattcttgtg gtagacaaag tctctccaaa agccagatag ccaaccccat
    10981 gtgtctccaa gagctgtctc ctacatccca gggaatacct aggaagatag catattagaa
    11041 atgaggaaag gtctcagcac aataacctaa gttcccacca caagaaacaa gaaaaagaat
    11101 agcaaaataa gcccaaagca ggcaaaagaa aggaaataac caaaagcaga aatcaatgaa
    11161 actgcaaata gaaaaataca taaacaaaaa actggttctt caaaaaacaa tcaagaaaat
    11221 ccataaacct gtagaaagac tgacaaaaag aaaaaacaca aatcattatt atcaagaatg
    11281 aaatgaagag tatcactata aatcaggcag tcattaaaaa gataatgagg aaatactgta
    11341 actttcggct tatacacatg acaacttaga agaaataatc tgattcttga aaaccacaaa
    11401 ctattaaaac tcaaccaaga tgaaataatc tgaatatcct ataaccatta aagaattaaa
    11461 ttcataattt aaaatctcct gataaaagaa atctccagac ccagatgccc tggcttcttt
    11521 gaggttcttc catgttgttt tatgtatcaa tcattcatta ttttttatcg ctgagtagtg
    11581 ctgcatggta tagaatataa cagtttgttt ataccattca cctgttgatg gacatttgtt
    11641 ggttccagtt ttgggctatt atgtaaagct gctatgagca ttcatttaca agtctttatg
    11701 tggacataag ctttcatttc tcttgggcaa atacctagga ctgggatggc taaatcatat
    11761 gataagtgta tatttaaatt tttaaggaac tgctaaaagt ctttttcaag ttaattgtac
    11821 cttttgacat tcccgccagc agtttatgtg tacaaaatgt ataattacat ttatgtaaaa
    11881 ctataaaatg caaactaatc tataataatg caagcacatc attggttgcc tggaatgggg
    11941 tgggcgaggg gaaatgatta caaaagggca aagggaaact tctggggctg atatatgtgt
    12001 ttactctctt gattgtggtt atggttcaca agtgtagcca tatggcaaaa cttaacaaat
    12061 tgtacacttt aaatatatgc agtttatcat acatcaatta tacctcagta aaggtgtcag
    12121 aaataacagg atatttatat ttaaatctac ctttgaatta ccgattgtga ctgaggtctc
    12181 atgtggctta ctggtgaatc cagtagttga ggaaacgaaa gccgtcactt ctgctaactc
    12241 ttttaccaac tcacctgctg tcaccttaca caaccccaac tgtgtttcag ctttggagta
    12301 atgaacacac cattttcttc ctacttaaaa gtccactcag gataatgatt aagaaataca
    12361 ttgatgccga gtaataaata ctttaaaaaa agttaaatgt gaacatttgg ctttcacagc
    12421 tcttgactgt ctttggcgaa ccttgacata aagctgcctt ttccatcttg ggctgctgac
    12481 aaaaaagcct aagaaagaaa gagggtgtgt acagaaaatt acatgccata gaaaaatacc
    12541 atacacaggc cgggagcggt ggcactttgg gaggccaggg cgggtggatc atttgaggtc
    12601 aggagtttga gaccagcctg gccaacatgg tgaaaccccc gtctctacta aaaatacaaa
    12661 acttagccgg gcatggtggt gcacacctgt agtcccagct acttgggagg ttgaggcagg
    12721 aggatcgctt gaacccagga ggcagagatt gcggtgaact gagatagtgc cactgtactc
    12781 tagcctgggc gacacagtaa gactccatct ccaaaagaaa gaaagaaaga aagaaaaaaa
    12841 tgccatacag atgaatcttt aaagatttta atttatatat acctcttcta ccattcattg
    12901 gctggagtag ttgaacagac atcagcaggc acaatgctag gcaggcactg gagattcagt
    12961 gatgaataaa acaaaactga cctggaacct ggcctcctga agcttctctt catctgtcta
    13021 aattcctttc tttcaaggcc cagtgcaagt gacaccttca tcaggaaggg cttccacatg
    13081 attctatctg caaatctccc ttttctgaac tattatgctt atagtctgta ccaggccaca
    13141 tgacatatgt tattttgtgg cattctagaa ttattccaat cttttcattc ttataattgg
    13201 tgtgttgtat tcaataaata atgttgttat tccagttttc atcactggtc acgcaagagt
    13261 cctctcttta ttatatttta tccccatagt tcaccccgtt tcctccccat cctaagtaac
    13321 tattaccata cctaaatata tatctaatta ggttgtatgt tttcttgcaa aatgagcact
    13381 atcttctgtg cacatatatt tgtgtatgtg aacagtattg tgttagcgtt gcttctttat
    13441 ttcttcactt atgactatgc ctctagtaca tatccatgtt gttatgtatg catttattcc
    13501 attgcttcta cccgctatac ctcatcgtgt acctctacca catgtcatct tccccctttt
    13561 ccaaggacag ccacttgggt ggcttccaac ttgcccaaca actattctac agttatttta
    13621 tgtatgttac tttggctcca gctcaattgt gaactgcttg tagataagga ccatgttttt
    13681 ctttacctgt tactcctgct gatttcctat tagtgcctgt gcatgttttc tgctgtaagg
    13741 tgttaaatgt taaagtaaaa ttaataatag tagaagtaag gagttgccag tggaatcttc
    13801 ctgagctgaa tctaatcatg gctttacccc ttactagctt tgtgaccttg accttggaaa
    13861 agtaaaacct tgttggtctt tcttcatcta tcaaggtagg taataccatc tatcttagtg
    13921 ggctgttatg aggaatgagt taattaacta atactaagca ctccagtaca gtagaagaca
    13981 tacaacaggt gtttaatgaa taataggtgc aatgaatcct acctgctgct tcaaattaca
    14041 gccatctgta cctgtcaact tttctaagag tataagcatc ttggaggtaa ggtcatttca
    14101 aatacttctt tatatctggt cattacccag cactctgctt tgtgtgaaat attctataca
    14161 tttatgttgc tatggtttgg atgtttttgt cccctccaaa attcatgtcg aaacttaatc
    14221 cccaaagcaa cagtattaaa ggatgtggcc tttaagaggt gactgagtaa tgaatgagat
    14281 taaatgctct tttgaaagca ttttgctcct ctttcccttc tgtcccttcc accatgtgag
    14341 gacatacatt cctccactgt ggaggatgca gcaatgaggt gccatcttgg aagcagagat
    14401 cagccttcac cagacactaa ttctgctggt gcattggtct tggaattccc agcctcaaga
    14461 gccaggaaaa acagatttct gttgtttata aattaccaaa tctgtggtat tttgttatag
    14521 cagcacaaat ggactaagac aaatctgtta acttagattt taagcatatg tgctaaagta
    14581 ttttaaaagg ttattttatc caagaatata gtatgagtta ataccttttt tgcaagattc
    14641 atggcaatct tttattattt attttttatt tcattccatg ttggaagcaa agtcatatct
    14701 attaaaaagt aaaatcacaa attagtcttt gattattcag aagcataaga agattgctgt
    14761 tttcatgttt tccatttctc cctccagtgg cttgaaaagt acaggtgctc ttttcagtca
    14821 tgttttgtct taaagatttt aaaataagaa gagtctgcat cctgtaaaag agggacagaa
    14881 acatggatca gtacctactc ctatttactc cagtttttaa catttaagtc cttctgtttt
    14941 gaggagctgt atcattatga ttcactatta agaatcttta caaaagttca gaaactgctt
    15001 aaattagaat ttaaaaatca tagccaaaat tctagatgta cacaaaagta cttctaatga
    15061 gtttagcatc atctctggtt tagaggaggt ataaatagca ttggactgca atgctaaatt
    15121 ctctataatg acttttctgg atcagcatat catacctaca ctgacttgcc ctaataaata
    15181 aaaacaatga gtcagattat gtagaattga gatatatgga agataactct ttaaaattat
    15241 ttgtggccag gcaggcactg tggctcatgc ctgtaatccc agcactttgg gaggccgagg
    15301 tgggcagatc acctgaggtc aggagttaga gaccagcctg gcaaaacccc atctctacta
    15361 aaaatacaaa aattagctgg gtgtggtggt gtgcacctgt aatcccagct acccgggagg
    15421 ctgaggcaag agaattgctt gaatccagga ggcggaggtt gcagtgagct gagactgcgc
    15481 cattgcactc cagcctggcc aacaagaggg aaactctgtc tcaaaaaaaa taaaaagaaa
    15541 aaaaaattat ttgtgaactt tttgtatatt gcttaaggaa taaaacaagg caacctgata
    15601 atccccaaga tgtgatgttt cttttcagaa gatatgcatt taccactttc aaaactttgc
    15661 actaagaaag acaaaataat aataatgata atacaaaatt cagtgtagcc actgttcttg
    15721 atccctaaaa ataataaaga ttcataaaaa caaagttcca gacatacaga ctaaagaagc
    15781 aaattctagt taacaagtac tattagcttg aaataagcta tgctagcatt ttcttaactt
    15841 agacgcttat caataagaaa atttatatat atacatatat ataaaatata aaatagtggg
    15901 agagaggaag agtacagact ataaagaatg aggtattatg tcctaaaaat tgctttgaga
    15961 aatgacagaa tgcccagctt ataataaaga gtgacaaagt agtaagacta tataataagc
    16021 aatatttcaa agatggtggt aggaagaaaa aggctgtcat ttttttagaa aaacctagat
    16081 gtaaaaaaaa tgcgagattt gctaaatgat gtttatattt tacagttaga tattctctaa
    16141 acaaaacaaa atatccttca tatggacatt tctggaagta ctactacagt gggactgaaa
    16201 ttctctagtc cctggtccct ctttcccctt tgaaaaaaaa atcacttcta taatatattc
    16261 tttctctgcc ctattattta aattgagaat gtgaaccagt acagacatta tggaaaatac
    16321 ggaaattcct caaaaaatta aaaatagaat taccatctga tccagcaatt ccacttaagg
    16381 gtataaatct aaaggaagtg aaatcagtac cttgaagtga tacctacact cccatgttca
    16441 ttttagcatt attcataata gccaagatat ggaaacaacc taagtgtcca ttagtgaatg
    16501 aatggataaa gaaaatgtgt gtgtgtgtct gtgtgtgtat atatatatat ggaatattat
    16561 tccacaatgg aatatttttc agccataaaa caatggaact cctggcattt gtgaaaacat
    16621 ggataatgaa tggacgttaa tgctaagtga tataagcaag atacagaaaa acaagtacta
    16681 tgtgatttca cttctgtgga atctaaaaag tcatactcaa aagcagagta gaatgatggt
    16741 tgccaggagc cagaagatgg aggaaatggg gagatcttgg tcaaaaggta cacattttgg
    16801 ccaggcacag tggctcacac ctatgatccc aacactttgg gaggccaagg taggtggatc
    16861 gcctgagccc aggagtttga gactagcctg ggcaacgtgg caaaaacccg tctctacaaa
    16921 aactacaaaa cctagccagg catggtggtg tgcgcctata gtctcagcta ctcaggaggc
    16981 tggggtggga ggattgcttg agcctgggag gtagagatgg gagtgagcca tgatcacgcc
    17041 actgcagact ccagcctggg tgacagggcg agaccctgtc tcaaagaaaa aaaatggtag
    17101 atattttcag ttataagata aataacttat gttattataa tttacagatt ctaaggatct
    17161 aatataccgc atggtgacta cagttaataa tactgtatag catatttgaa atttgctaag
    17221 aagattttaa gtgttctcac cacacacaaa aaaaggtaac tgggtgacat gtattaatta
    17281 gcttgattgt ggtaatcatt ttacagtgta tattagatca tcacaatgta taccttaaat
    17341 atatataatt tttatgtgtc aattataaag aaaatctttg atcattaagg aagctgaata
    17401 tcctgctata tctaactcaa gctgagaagg gggaaaaagc acaatagcta acacttagaa
    17461 cactccaagt tgtgttttaa gtgcttttca tatattaaat tcatgtaatt cccataacaa
    17521 tcctgtgact gggcactatt atcatcatta atctccatct tatattaata gatggggaga
    17581 ctgagtgata gagaagtaac ttgctttaag ggcatggggc agagctggga tttgaaccca
    17641 ggtagcctag caccaggctg catgctctgc caggaggctg tgcttcctct gtagtaaggt
    17701 ggcctgtccc tctcaactct ttccatcact gggcacaaag ctactgcatc agctgtcctc
    17761 catatttaaa actcaggtat actctttgat gaaactctac ctttagagct tctacccaca
    17821 ctaccaagtc ccaacaatac caaaacactc ataagggatc tggcccaaag caaactgttc
    17881 cacattacta cttggtagaa aacgaaaagc tcctttttga tttttcacac tctggacatt
    17941 ttagtgtgtc atgacccagt ctgataacct tttatgtctc ttaagcattt tgttgtgttt
    18001 gtaacttttt accccctaat tcattttcac tgtcctgcaa agagttggaa taaattaaat
    18061 gtctaacaa
//
