LOCUS       NM_001257101            7064 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens polycomb group ring finger 5 (PCGF5), transcript
            variant 4, mRNA.
ACCESSION   NM_001257101
VERSION     NM_001257101.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7064)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 7064)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 7064)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 7064)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   5  (bases 1 to 7064)
  AUTHORS   Hauri,S., Comoglio,F., Seimiya,M., Gerstung,M., Glatter,T.,
            Hansen,K., Aebersold,R., Paro,R., Gstaiger,M. and Beisel,C.
  TITLE     A High-Density Map for Navigating the Human Polycomb Complexome
  JOURNAL   Cell Rep 17 (2), 583-595 (2016)
   PUBMED   27705803
REFERENCE   6  (bases 1 to 7064)
  AUTHORS   Woodsmith,J., Jenn,R.C. and Sanderson,C.M.
  TITLE     Systematic analysis of dimeric E3-RING interactions reveals
            increased combinatorial complexity in human ubiquitination networks
  JOURNAL   Mol Cell Proteomics 11 (7), M111.016162 (2012)
   PUBMED   22493164
REFERENCE   7  (bases 1 to 7064)
  AUTHORS   Luo,T., Kuriakose,J.A., Zhu,B., Wakeel,A. and McBride,J.W.
  TITLE     Ehrlichia chaffeensis TRP120 interacts with a diverse array of
            eukaryotic proteins involved in transcription, signaling, and
            cytoskeleton organization
  JOURNAL   Infect Immun 79 (11), 4382-4391 (2011)
   PUBMED   21859857
REFERENCE   8  (bases 1 to 7064)
  AUTHORS   Vandamme,J., Volkel,P., Rosnoblet,C., Le Faou,P. and Angrand,P.O.
  TITLE     Interaction proteomics analysis of polycomb proteins defines
            distinct PRC1 complexes in mammalian cells
  JOURNAL   Mol Cell Proteomics 10 (4), M110.002642 (2011)
   PUBMED   21282530
REFERENCE   9  (bases 1 to 7064)
  AUTHORS   Wakeel,A., Kuriakose,J.A. and McBride,J.W.
  TITLE     An Ehrlichia chaffeensis tandem repeat protein interacts with
            multiple host targets involved in cell signaling, transcriptional
            regulation, and vesicle trafficking
  JOURNAL   Infect Immun 77 (5), 1734-1745 (2009)
   PUBMED   19273555
REFERENCE   10 (bases 1 to 7064)
  AUTHORS   Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
            Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
            Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
            Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
            Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
            Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
            Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
  TITLE     A scan of chromosome 10 identifies a novel locus showing strong
            association with late-onset Alzheimer disease
  JOURNAL   Am J Hum Genet 78 (1), 78-88 (2006)
   PUBMED   16385451
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL731553.12, BC051845.1, AC026227.8 and BQ420347.1.
            
            On Aug 14, 2020 this sequence version replaced NM_001257101.1.
            
            Transcript Variant: This variant (4) differs in the 5' UTR compared
            to variant 1. Variants 1, 2 and 4 all encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051845.1, SRR14038196.3203377.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AL731553.12        85029-85117
            90-3706             BC051845.1         46-3662
            3707-6701           AC026227.8         100514-103508       c
            6702-7058           BQ420347.1         17-373
            7059-7064           AC026227.8         100151-100156       c
FEATURES             Location/Qualifiers
     source          1..7064
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q23.32"
     gene            1..7064
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /note="polycomb group ring finger 5"
                     /db_xref="GeneID:84333"
                     /db_xref="HGNC:HGNC:28264"
                     /db_xref="MIM:617407"
     exon            1..89
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            90..384
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     CDS             273..1043
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /note="ring finger protein (C3HC4 type) 159; RING finger
                     protein 159"
                     /codon_start=1
                     /product="polycomb group RING finger protein 5"
                     /protein_id="NP_001244030.1"
                     /db_xref="CCDS:CCDS7413.1"
                     /db_xref="GeneID:84333"
                     /db_xref="HGNC:HGNC:28264"
                     /db_xref="MIM:617407"
                     /translation="MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIV
                     QHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNK
                     PQENGQDDTSKADKPKVDEEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGL
                     MKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLR
                     GENFRCLNCSASQVCSQDGPLYQSYPMVLQYRPRIDFG"
     exon            385..481
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            482..537
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            538..597
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            598..746
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            747..845
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            846..935
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            936..995
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     exon            996..7064
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3681..3686
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /note="hexamer: AATAAA"
     polyA_site      3711
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /note="major polyA site"
     regulatory      6967..6972
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /note="hexamer: ATTAAA"
     polyA_site      6991
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
     regulatory      7039..7044
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
                     /note="hexamer: ATTAAA"
     polyA_site      7064
                     /gene="PCGF5"
                     /gene_synonym="RNF159"
ORIGIN      
        1 gggctccctc acctaccgcc ccacgcgcgc gcgctcgcgc accacgcgcc ccgcgcggcc
       61 cgcccggatc gtggcctctc gagagcaaga catgggaaag cggaaccacc aaaaggagtg
      121 atgatcaacg atctcatgat aaatctggat gctagttctc atgcctcagg acatcctact
      181 gggaacgaca caccagctcc tgggatcaga ctttcatcta cttaggaccc ctctttgccc
      241 agactactaa agccagtctt cactagccac gaatggctac ccaaaggaaa cacttggtga
      301 aagattttaa tccttacatt acctgctata tctgtaaagg gtatctgatc aagccaacaa
      361 cagtgacgga atgcctccat acattctgta agacttgtat tgttcagcac tttgaagata
      421 gcaatgattg cccaaggtgt ggcaaccaag ttcatgagac aaatccatta gaaatgttga
      481 ggttggacaa tacattagag gaaattatat ttaagctggt ccctggacta cgagaacaag
      541 aacttgagcg tgaatctgaa ttttggaaga aaaataagcc tcaagaaaat ggacaagatg
      601 atacttcaaa agctgacaaa ccgaaagtag atgaagaagg tgatgaaaat gaagatgata
      661 aagattatca cagaagtgac ccacaaattg ctatctgtct agattgttta cgaaataatg
      721 ggcaatcagg ggacaatgta gtaaagggtt taatgaagaa attcattcga tgttctacac
      781 gtgtaactgt gggaactatt aaaaaatttc taagtttaaa actaaaactt ccaagttctt
      841 atgagttgga tgtgctgtgc aatggtgaaa ttatggggaa ggatcatact atggaattca
      901 tctacatgac aagatggcga ctaagaggcg aaaactttcg gtgtctgaac tgctcagctt
      961 cgcaagtctg ctctcaggat ggccctttgt atcagtcata ccctatggta ctgcagtatc
     1021 gaccaagaat tgatttcggt tagaccaagg ggcccagacc tcactgagat gaatcctgca
     1081 ctatttgttt actcgtcaac agattgcaca gttaacggtg tgtggactag aggaacacaa
     1141 ccagattttc agcatgcaaa taaggccatt gtctatctct aaattgtcag ttgcattcat
     1201 gttgtttcta ttaggagcaa accaagtgcc attctgctac tgaaccatct gcataaggta
     1261 tttgtgttgt ctcaaagtgt gcaagtcatg gtaaaaatca gttagctgtg ccgccatgat
     1321 tcacccttct gaatattttg cttgcctgtt ccaagattgt tctaatgttt aattacacta
     1381 gtaaaatggc tcaatttttg tggtgttgca gttttcacat acttactctt ttattcttgt
     1441 ttaaatagcg tactctacaa gaaactaata attatatctt gaaattattt tgtatggaag
     1501 tatatttaga aaagtggttt ttgagccact gtcttgttct tgataagctt tttgtgtgaa
     1561 aaaaagttca ttcttgagtg tgcaagtcct tttgccaaga attccaatta ttctgtaaca
     1621 ttagagcaca atataattgt agacattcta agcatctgtc cgtgtagtct accaattgca
     1681 caaggaaggc atgttagccc tccagattga aaatgtatgt gacctcttga actgaagtta
     1741 gattcccaac cattcaaaat gttggcagct gatcacattt acttctgata aaagtaatgt
     1801 gtaagtaagg ttaatcttct ttcataatgc cttatgacaa gcaggtgctg cttcatgaaa
     1861 cgtcattgta tagcccattt catgtatcat tacattgttg ctgttattta atgagtgcat
     1921 tatttctctt tttaagttgg ccttaggtat atgtcattgt ggcatgcaga gggttatgac
     1981 gattttaaat attaggattt ttagagcaca taacattagc tattttatgg atttcaaaag
     2041 tctcaaaaca gttgtagatt aaaactgtta gttacctttc acatttccaa actatgtgca
     2101 taaaatagaa taaatgcagt atagaactat gctaaccaaa attaataggt taagggtatt
     2161 ttattttaaa tcctgtagta attggggaaa tgagaagatt attattttat acatgagttc
     2221 attaagatca gaaatacaaa atgtcctgta ttttgcagtt ttgttaagtc ttccattcgt
     2281 tttaggatta gtctgcaagt caaagaaagt cttgttacct taaattatat gaaaactgtc
     2341 attttaaatc ttttaatatt tacagttttc aaaaacctta cttggaaatt gctttgaaac
     2401 aaacaagcta acctttgaaa cttaggaaaa aatcttgaaa gttaggaaaa atatttgaga
     2461 aatatgacga gcacaatctg tgtgttacac acatttagtt tttatactgc atatgtggta
     2521 aatgtgtcac attttccagt aaaatgtatc agaaatcaat gccttctgaa tttcaaaatg
     2581 attcttagaa ataagatatt gtacaactct agcaaacata caaagtacag ctaaatctta
     2641 atatatttca ctatgtaaaa ggctgaaact tcataattat ctgttccttc tatctttttt
     2701 tgagtcaaaa agtctattaa atttttctgt tgttgttcca actttggtga aaaaggttat
     2761 ggcaatactt taactttgtt ttgttacatt gtttttgttc ttggaatggc tcacaagcag
     2821 aatttaaaag gcagattttc attaactata aatggctgaa aaaactgaat ttactatcta
     2881 gctacagaaa ttatttttct atggtgtgaa actgttccca gacatcccta agaactttta
     2941 caaattatta taaatttgtc acacctaggt cagcgattaa aatagtgttt tgcaaatgga
     3001 attttaatta actcaaaatg aattaagagt gcattttaaa aatcacaagt gagactttga
     3061 tgttttggcc ccccagccaa aacttaatgg tcataaatga attttatcta caaaatctct
     3121 ttaaatttgg ctggttgcct tgtcatatgt aatttcacta ttttccaagg aaatatatag
     3181 gaagcaatta tgaaactgag aatagtttta tatagaattc ttttatttac tgataatgca
     3241 ttaacatttt tattgaaatg caatggaata tgtgccaaaa cacgtgaaaa gcttacataa
     3301 agaaaggcat cagttgtcgt ttggagaaag gtacacattt ttttgatggt cctaagtgat
     3361 atggtattac tactagaatc acagatttct tcaactgact tattttggta tattcaacta
     3421 cagctttcta aggataggac tactttcatg tctagtaata cactgtattc cccgttaatt
     3481 atcccttaag tcagattgta gaatttgcaa gaaactaggt atagaaaaaa tgtacaggca
     3541 acttttgtgg ttagctttat aaatttaggg tgcttataaa atgataaaat gaattcttta
     3601 aataacctat aggaatcatc tgaatctgta acatcagaga ctaaaactaa aagttttctt
     3661 taatctgttg tttcttaagc aataaactga aagaccttta cttccataaa agattttgtt
     3721 atctctttta tctgccttag aaattataag tataaaaggg tcaagggaac ttagatataa
     3781 agaatgactg tggtttataa acattacttt aattgaagta atcacatcag ttaatagaga
     3841 aatcaaaata tgtatggcct tttctctaga ttagcaaaac agctttacaa agtatgaaaa
     3901 aataaactaa aatgctcatt gatgaggtaa tactcagtct ggagtacagg taacttgggt
     3961 aatgcctttt aactactctt agaggagtat attatttctt tatacattaa acatctatcc
     4021 catagtaatg tgccacattt tataaacgta atgactttgc tcaactacat tacacactca
     4081 aatgtaatct aaatttaaac tgattattta aggaaaaaaa gtgtgttata taatattgtg
     4141 aactgtttag ctttactgaa atatttaaga gaaagtgcct cattactaaa gtgcatttct
     4201 gttttaaatt tactgcataa agtttgagtt atctgtacct gtctcttatg aatggtttca
     4261 tatctaaata ggctcttgta agttaatttt tttggaagat tttcataaga atatagatat
     4321 caccaaagac attttacagt aaattaataa ccatgttgga gagacggttt taacagtttg
     4381 gaggttggaa atttttagat tgcaatttaa ttttatatag ttaggcaata accttgatta
     4441 attgctaaaa tatcaccaaa gaaaggcttt aaactgaatt ttcttggtga gatcagtcaa
     4501 atgcaggctt ttcttgcaat aatcagaaca cacttccttt caaatatgtt cattgttttt
     4561 cagcatcatc taacagatct tagtaaatct aaatcctcaa agatgagaaa gaggtaaaca
     4621 caacaaatag ccttcctctg catgaaaagt gagagaaata catactttga aaagaaagtt
     4681 cagattttta atttgagagg gtttttattt catggaggca gtgttaacta aaattaagct
     4741 tagatttagc tcctgtatta ttcataatat gagaaatttt attaaaggca gactttggta
     4801 aaagtgccaa cacacttact tgtatagaaa agacttcatt ctatgggatt tatataagta
     4861 agtgctttct ctatattcaa aatatttcat aaggacctgt ggtttttttc cccttaaaaa
     4921 gcaactctag gccgggcaca gtggctcatg cctgtaatcc cagcactttg ggaggccaag
     4981 gcaggtggat cacttgaggt caggagttcg agaccagctg gttaacatgg tgaaacccca
     5041 tctctactaa aaatacaaaa attagccagg tgtggtggca cgcgcctgta atcccagcta
     5101 catgggaggt tgaggcagga gaatctcttg aacccaggag gtggaggttg cagtgagccg
     5161 caattacacc actgcactcc agcctgggtg acacagcgag tctccatctc caaaaaaaat
     5221 tcaactcttg gtcttgtttc tcagcactta gtttattgtt attagaattt agccatacag
     5281 ccaactttga caaaatgggt cacagaacaa gcatgtacat caagaggaag ttccatatcc
     5341 cccttgtacc atttctcctt gggaactcat gctatgggct accttaaagg taaaactcat
     5401 cttatggagt ctttctgata ggtcactagg taaaactcct tggatagggt gaaaatggat
     5461 gcacactcta ttacatactc tggtttatca taaggaattt tccagaaagc taagctttat
     5521 actaataaga tattggttgg tagtaggaac ttcaaaaatg aatgagtttg ccataacttt
     5581 aattttctgg attagaaaca caaaacttga aatgcaatta tcaatatttt gtaatatata
     5641 ttcctacagt ttgggtagaa ataaggaaca tgtctgctag atctggttta tgaaaaagtg
     5701 aaaaatatta aatacaccag agactcaaac cctttcaagg cacacaataa ctgttctgga
     5761 tttacctgac aaacctagtt gagtagcatt ttgacagaaa atatcagact gaaagttcat
     5821 tcaaatgtac ttaaatgtac aatacagtgt tcaatagttt ttattgcagt gatgtttttc
     5881 caataattta agtaattctc ttcctagtat aatacagttt tcataaataa tgtttacttg
     5941 ctttctttat attttcaaat aaaattaaaa tgctcgagca cttcctttca gaaagttata
     6001 aaattaaaaa taattatttt aaatgctcat tcaaatgtgt ctgtatactt gctatgcccc
     6061 tttttctata attccaaact gagactgatt tttcagagat ttttaacttt aataatttta
     6121 aatctagaat caagtgaaac agatatgtta aatactgagt ctagttttct tccatcttat
     6181 ggagcttcat ggaataagaa actaatctag tgcaaatgaa gattaaatat ttctgggtga
     6241 tggagagata gtcaacaaat ttatttatcc atcctctgca catcagtcca ctggagcagg
     6301 agttctacac attaaaaatg taatgggatc agcctagcat tgtttggtgt tcttttgttg
     6361 tattttttag aatgggggtg ggggcctaag tgtccttatg aagctgtggt ccacgacagg
     6421 agcttgttgg gggagtacca gggttctgct gctttcctgc atctgagcaa cacaacagag
     6481 atcatcagtt ttaaatagag tagccctcac aatcaaaata tcatagaata tattgtaaag
     6541 ttatgttgct aattttcctt tgaaatataa aatattttaa gctttttgtc aaaagtggta
     6601 acatcttaat acaaataaaa acctttttgt ggttgtaaga tttagcttat aaatcattca
     6661 aattgaagtg aaagaattac caggtcattg ttaatgactt agtctattaa gaatatatgt
     6721 atttttgtaa aggaaaagca cttgtagata tttaatcagt acaagatatg tcttttgcag
     6781 aaataaaatg ctgcttagag attctcctta aatatttttt atttttgtgc tcaaatgtat
     6841 tttctgttga tctatggaat gttctgtaca aagctgtata attgtactgt tgggctagat
     6901 actttttttt tttaatctgg acttagccaa gtatatttca ccatgttaaa atacagtatc
     6961 tttgttatta aaaattaaat tgcataattt attattgttt gtcatcttta atattagtca
     7021 ctgtagattg cagccttcat taaaaatatc tcctttaagt acta
//
