LOCUS       NM_016500               1185 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens polysaccharide biosynthesis domain containing 1
            (PBDC1), transcript variant 1, mRNA.
ACCESSION   NM_016500
VERSION     NM_016500.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Lim,S.H., Snider,J., Birimberg-Schwartz,L., Ip,W., Serralha,J.C.,
            Botelho,H.M., Lopes-Pacheco,M., Pinto,M.C., Moutaoufik,M.T.,
            Zilocchi,M., Laselva,O., Esmaeili,M., Kotlyar,M., Lyakisheva,A.,
            Tang,P., Lopez Vazquez,L., Akula,I., Aboualizadeh,F., Wong,V.,
            Grozavu,I., Opacak-Bernardi,T., Yao,Z., Mendoza,M., Babu,M.,
            Jurisica,I., Gonska,T., Bear,C.E., Amaral,M.D. and Stagljar,I.
  TITLE     CFTR interactome mapping using the mammalian membrane two-hybrid
            high-throughput screening system
  JOURNAL   Mol Syst Biol 18 (2), e10629 (2022)
   PUBMED   35156780
REFERENCE   2  (bases 1 to 1185)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
REFERENCE   3  (bases 1 to 1185)
  AUTHORS   Cheng,J., Kapranov,P., Drenkow,J., Dike,S., Brubaker,S., Patel,S.,
            Long,J., Stern,D., Tammana,H., Helt,G., Sementchenko,V.,
            Piccolboni,A., Bekiranov,S., Bailey,D.K., Ganesh,M., Ghosh,S.,
            Bell,I., Gerhard,D.S. and Gingeras,T.R.
  TITLE     Transcriptional maps of 10 human chromosomes at 5-nucleotide
            resolution
  JOURNAL   Science 308 (5725), 1149-1154 (2005)
   PUBMED   15790807
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC001220.1, AI919559.1 and AC233281.2.
            
            On May 17, 2019 this sequence version replaced NM_016500.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163655.392684.1,
                                           SRR7346977.516230.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000373358.8/ ENSP00000362456.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1069              BC001220.1         127-1195
            1070-1140           AI919559.1         53-123              c
            1141-1141           AC233281.2         6696-6696           c
            1142-1181           AI919559.1         12-51               c
            1182-1185           AC233281.2         6652-6655           c
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq13.3"
     gene            1..1185
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /note="polysaccharide biosynthesis domain containing 1"
                     /db_xref="GeneID:51260"
                     /db_xref="HGNC:HGNC:28790"
     exon            1..107
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..779
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UPF0368 protein Cxorf26; polysaccharide biosynthesis
                     domain-containing protein 1; protein PBDC1"
                     /codon_start=1
                     /product="protein PBDC1 isoform 1"
                     /protein_id="NP_057584.2"
                     /db_xref="CCDS:CCDS14432.1"
                     /db_xref="GeneID:51260"
                     /db_xref="HGNC:HGNC:28790"
                     /translation="MAATSGTDEPVSGELVSVAHALSLPAESYGNDPDIEMAWAMRAM
                     QHAEVYYKLISSVDPQFLKLTKVDDQIYSEFRKNFETLRIDVLDPEELKSESAKEKWR
                     PFCLKFNGIVEDFNYGTLLRLDCSQGYTEENTIFAPRIQFFAIEIARNREGYNKAVYI
                     SVQDKEGEKGVNNGGEKRADSGEEENTKNGGEKGADSGEEKEEGINREDKTDKGGEKG
                     KEADKEINKSGEKAM"
     exon            108..173
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /inference="alignment:Splign:2.1.0"
     exon            174..233
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /inference="alignment:Splign:2.1.0"
     exon            234..374
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /inference="alignment:Splign:2.1.0"
     exon            375..486
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /inference="alignment:Splign:2.1.0"
     exon            487..1185
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1047..1052
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /note="hexamer: AATAAA"
     polyA_site      1071
                     /gene="PBDC1"
                     /gene_synonym="CXorf26"
                     /note="major polyA site"
ORIGIN      
        1 gccagttgag aaggactctg atccggctca gctttccaat cagctgcgga aggagccacg
       61 ctttcggggg ttgcaagatg gcggccacca gtggaactga tgagccggtt tccggggagt
      121 tggtgtctgt ggcacatgcg ctttctctcc cagcagagtc gtatggcaac gatcctgaca
      181 ttgagatggc ttgggccatg agagcaatgc agcatgctga agtctattac aagctgattt
      241 catcagttga cccacagttc ctgaaactca ccaaagtaga tgaccaaatt tactctgagt
      301 tccggaaaaa ttttgagacc cttaggatag atgtgttgga cccagaagaa ctcaagtcag
      361 aatcagccaa agagaagtgg aggccattct gcttgaagtt taatgggatt gttgaagact
      421 tcaactatgg tactttgctg cgactagatt gttctcaggg ctacactgag gaaaacacca
      481 tctttgcccc caggatacaa ttctttgcca ttgaaattgc tcggaaccgg gaaggctata
      541 acaaagctgt ttatatcagt gttcaggaca aagaaggaga gaaaggagtc aacaatggag
      601 gagaaaaaag agctgacagt ggagaagaag agaacaccaa gaatggagga gagaaaggag
      661 ctgatagtgg agaagaaaaa gaggaaggaa tcaacagaga agacaaaact gacaaaggag
      721 gagaaaaagg gaaagaagct gacaaagaaa tcaacaaaag tggtgaaaaa gctatgtaag
      781 gtatacaggg aacagcactc tagaagctat gactcaattg agactacaag taccacggtg
      841 ctacttgcac agaccccttt ggttaaatgt aaattcttgt acaattgaag gatacgcaga
      901 aggacatctt tctagtctaa cagtcaggag ctgctctggt cattcccttg tatgaactgg
      961 tctaaagact gttagtgggg tgttagttga tttttcctgg tatactgttt cttggctgac
     1021 actactggtc aagtaagaaa tttgtaaata aatttctttt ggttcttatt atctatatct
     1081 gtgactgact ttaaaaaggt atttgacact tgaaattttt ttcaaatatg taatctcatc
     1141 accatgtctt atataagata atttactcct gtttcttact gcttc
//
