LOCUS       NM_001144874            1986 bp    mRNA    linear   PRI 30-JUL-2024
DEFINITION  Homo sapiens prostate and testis expressed 4 (PATE4), mRNA.
ACCESSION   NM_001144874 XM_001132703 XM_001133280 XM_001715514
VERSION     NM_001144874.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Margalit,M., Yogev,L., Yavetz,H., Lehavi,O., Hauser,R., Botchan,A.,
            Barda,S., Levitin,F., Weiss,M., Pastan,I., Wreschner,D.H., Paz,G.
            and Kleiman,S.E.
  TITLE     Involvement of the prostate and testis expression (PATE)-like
            proteins in sperm-oocyte interaction
  JOURNAL   Hum Reprod 27 (5), 1238-1248 (2012)
   PUBMED   22402205
  REMARK    GeneRIF: PATE proteins are involved in sperm-oolemma fusion and
            penetration but not sperm-zona binding.
REFERENCE   2  (bases 1 to 1986)
  AUTHORS   Li,J.Y., Wang,H.Y., Liu,J., Liu,Q., Zhang,J.S., Wan,F.C., Liu,F.J.,
            Jin,S.H. and Zhang,Y.L.
  TITLE     Transcriptome analysis of a cDNA library from adult human
            epididymis
  JOURNAL   DNA Res 15 (3), 115-122 (2008)
   PUBMED   18390568
REFERENCE   3  (bases 1 to 1986)
  AUTHORS   Levitin,F., Weiss,M., Hahn,Y., Stern,O., Papke,R.L., Matusik,R.,
            Nandana,S.R., Ziv,R., Pichinuk,E., Salame,S., Bera,T., Vincent,J.,
            Lee,B., Pastan,I. and Wreschner,D.H.
  TITLE     PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR
            proteins that are expressed in reproductive and neuron-rich tissues
            and possess neuromodulatory activity
  JOURNAL   J Biol Chem 283 (24), 16928-16939 (2008)
   PUBMED   18387948
  REMARK    GeneRIF: analysis of PATE, expressed primarily in prostate and less
            in testis, and additional PATE-like genes PATE-M, PATE-DJ, and
            PATE-B
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK123042.1, AW296313.1, AP000842.6 and AI674374.1.
            
            On or before Jan 28, 2009 this sequence version replaced
            XM_001132703.2, XM_001133280.2, XM_001715514.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK123042.1, DA865673.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465411 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000457514.3/ ENSP00000411439.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-684               AK123042.1         1-684
            685-713             AW296313.1         28-56               c
            714-1747            AK123042.1         714-1747
            1748-1753           AP000842.6         2099-2104
            1754-1983           AK123042.1         1754-1983
            1984-1986           AI674374.1         1-3                 c
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.2"
     gene            1..1986
                     /gene="PATE4"
                     /gene_synonym="PATE-B"
                     /note="prostate and testis expressed 4"
                     /db_xref="GeneID:399968"
                     /db_xref="HGNC:HGNC:35427"
     exon            1..102
                     /gene="PATE4"
                     /gene_synonym="PATE-B"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..341
                     /gene="PATE4"
                     /gene_synonym="PATE-B"
                     /note="prostate and testis expression B; prostate and
                     testis expressed protein 4; PATE-like protein B"
                     /codon_start=1
                     /product="prostate and testis expressed protein 4
                     precursor"
                     /protein_id="NP_001138346.1"
                     /db_xref="CCDS:CCDS44765.1"
                     /db_xref="GeneID:399968"
                     /db_xref="HGNC:HGNC:35427"
                     /translation="MRKMNTLLLVSLSFLYLKEVMGLKCNTCIYTEGWKCMAGRGTCI
                     AKENELCSTTAYFRGDKHMYSTHMCKYKCREEESSKRGLLRVTLCCDRNFCNVF"
     exon            103..219
                     /gene="PATE4"
                     /gene_synonym="PATE-B"
                     /inference="alignment:Splign:2.1.0"
     exon            220..1986
                     /gene="PATE4"
                     /gene_synonym="PATE-B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatacctcac tcagcacacc gtctgtcacc caaacaagca tccaatgagg aaaatgaaca
       61 cactgctcct tgtgagctta tcttttctct acctcaaaga ggttatgggt ctgaagtgta
      121 atacctgcat atacacagaa ggatggaagt gtatggcagg ccgaggcact tgcattgcaa
      181 aagaaaatga gttatgttca acaacagcct atttcagggg agacaaacat atgtactcaa
      241 cacatatgtg taagtataag tgccgggaag aggagtcctc caaaagaggc ctgttgagag
      301 tgacactgtg ctgtgacaga aacttctgta atgtcttcta atggagctta ggaacttgca
      361 gaggatcatc tgatcaagat ccagaatcaa gaccaaccaa catgaactgt tttatttccc
      421 acaccaaatt ccacactggc ctaagatccc agagagagct gcaggggctg tcctcattgc
      481 aatgaagggg ctccccacac cccacctcca ccactagatt cctaaaatca tgagcattga
      541 aacaaaatcc tccatgagct atgcttattc ttttgtcttc tactcctgat ttctgatttc
      601 tatcccttgt aggctaaata atggaccccc aaatatttct acatcctaat ctctggaacc
      661 tgtgaatgtt accttacatg gcaaaaggga ctttgaaaat gtgattaagg atcttgagaa
      721 ggggaggtta tcttgcatta tctggggggg ccctaagtgg aatcaaaatg caaaatgcaa
      781 taagatgcaa gtaaagggag atatgacaaa gaagaggaaa agatgatgtg ataatggaag
      841 cagagattgg agccatgtgc tttgaagatg gaggaatagg ccataagcta aaactaggag
      901 gccactagaa gctgaaaaag tcaaggaaat aggttctccc ctcagagcct ccagaaacca
      961 gccctgctga caccttgatt taagccctgt aagactcatt ttggatgtct ggcctccaga
     1021 actctaagcg ggtgtggttt tcagccacaa agtgtgtatt gttttaagcc actaagtttg
     1081 caataattta ttatagcagc aatgggaaac taatacaatc caaataaact tctaggaatt
     1141 caaatcattg gtaagcctga gtacccaggg gccagtctag gtgacaacag tatccaccgc
     1201 tcagggctta cagtgacctg caggaagaga ggaataacag agcacatgct atgaataaat
     1261 gtggagatca atttgtggat tttaaacttc atgacatgct gcagataatc ctttaggtgt
     1321 atctgtggta aatggtgcct tgctatgttc tgaagcaatc aaacatgatg tcctaatagc
     1381 tcaatttatc agttcctcat tagcttgtgt actcactgaa attcttttag cagttaatgt
     1441 ccttgtatta gtctgttttc atgctgctga taaggacata cccacgactg ggcaatttac
     1501 gaaagaaagg ggtttatcgg acttacagtt ccacgtggct ggggaagcct cacaatcatg
     1561 gcagaaggta aaaggcatgt ctcacatagt gacagacaag agaagagaga ttgtgcagga
     1621 aaactctccc ttataataac catcagatct tgtgagactt actcactatc acgagaatag
     1681 cacaggaaaa acctgccccc atgattcaat tacctcccac cggtccctcc cacaacacgt
     1741 gggaattgaa gatgaaattt gggtggggac acagccaaac catatcagtc cccttcttaa
     1801 aactctcctc tctagctcct atgactgtac atttgtagtt ctcccacctc tctgaagaat
     1861 cctctgtgag ggtctctggg gactttgttt tgatttgtta ttgtttttat attcagtctt
     1921 taacctatgt gaagccacct ttgtaatact gccttaagta aagatccagt attatttttc
     1981 tccata
//
