LOCUS       NM_001129883            1320 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens prostate and testis expressed 3 (PATE3), mRNA.
ACCESSION   NM_001129883
VERSION     NM_001129883.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Li,J.Y., Wang,H.Y., Liu,J., Liu,Q., Zhang,J.S., Wan,F.C., Liu,F.J.,
            Jin,S.H. and Zhang,Y.L.
  TITLE     Transcriptome analysis of a cDNA library from adult human
            epididymis
  JOURNAL   DNA Res 15 (3), 115-122 (2008)
   PUBMED   18390568
REFERENCE   2  (bases 1 to 1320)
  AUTHORS   Levitin,F., Weiss,M., Hahn,Y., Stern,O., Papke,R.L., Matusik,R.,
            Nandana,S.R., Ziv,R., Pichinuk,E., Salame,S., Bera,T., Vincent,J.,
            Lee,B., Pastan,I. and Wreschner,D.H.
  TITLE     PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR
            proteins that are expressed in reproductive and neuron-rich tissues
            and possess neuromodulatory activity
  JOURNAL   J Biol Chem 283 (24), 16928-16939 (2008)
   PUBMED   18387948
  REMARK    GeneRIF: analysis of PATE, expressed primarily in prostate and less
            in testis, and additional PATE-like genes PATE-M, PATE-DJ, and
            PATE-B
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            EF426753.1 and AP003087.2.
            
            On May 17, 2019 this sequence version replaced NM_001129883.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF426753.1, SRR5189667.131545.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000445202.2/ ENSP00000395505.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-196               EF426753.1         17-212
            197-197             AP003087.2         49175-49175
            198-826             EF426753.1         214-842
            827-827             AP003087.2         50774-50774
            828-1320            EF426753.1         844-1336
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.2"
     gene            1..1320
                     /gene="PATE3"
                     /gene_synonym="HEL-127; PATE-DJ"
                     /note="prostate and testis expressed 3"
                     /db_xref="GeneID:100169851"
                     /db_xref="HGNC:HGNC:35426"
     exon            1..74
                     /gene="PATE3"
                     /gene_synonym="HEL-127; PATE-DJ"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..322
                     /gene="PATE3"
                     /gene_synonym="HEL-127; PATE-DJ"
                     /note="acrosomal vesicle protein HEL-127; prostate and
                     testis expressed protein 3; secreted TFP/Ly-6/uPAR protein
                     PATE-DJ; PATE-like protein DJ"
                     /codon_start=1
                     /product="prostate and testis expressed protein 3
                     precursor"
                     /protein_id="NP_001123355.3"
                     /db_xref="CCDS:CCDS44764.1"
                     /db_xref="GeneID:100169851"
                     /db_xref="HGNC:HGNC:35426"
                     /translation="MNKHFLFLFLLYCLIVAVTSLQCITCHLRTRTDRCRRGFGVCTA
                     QKGEACMLLRIYQRNTLQISYMVCQKFCRDMTFDLRNRTYVHTCCNYNYCNFKL"
     exon            75..197
                     /gene="PATE3"
                     /gene_synonym="HEL-127; PATE-DJ"
                     /inference="alignment:Splign:2.1.0"
     exon            198..1320
                     /gene="PATE3"
                     /gene_synonym="HEL-127; PATE-DJ"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcacaagg gatttccggg tcaggatgaa caaacacttc ttgttcctct tcctccttta
       61 ctgcctcatt gtggcagtga catcacttca gtgcataaca tgccaccttc gcacacggac
      121 agaccgctgt agaagaggct ttggtgtctg tactgctcag aagggcgagg catgcatgct
      181 cttaaggatt taccagcgca atactctcca gatatcatac atggtgtgtc agaaattctg
      241 cagagacatg acatttgatc tcaggaatcg gacttatgtt catacatgct gcaactacaa
      301 ttactgtaac tttaaactct aagatatttg ccctcctgag gtctcgcttt ggaatgtccc
      361 caatgttgct catccttcac actctgctgg cccttgcttc ccttccgtgt ctgtcctgac
      421 aatacccctg ccctcgcatt aacctaagaa gactaaacta gtgtgatcct ttctggtgtc
      481 ttcagcttgg cttctccctc agtcagagaa tagtggttct gaacaatgga tttcttctat
      541 tattgggatt attggcatgg ccatattcca agaaacctgc cccaagagtt cctgtacagt
      601 aaaatttaaa gcaggaacat tctagaatct taatttgctt aactagttca ggtacactag
      661 aaagccttca gctaaaaatt cacaatattt ttatctaaaa ttcccatgta tccggagaat
      721 gactaagcag aaatagcaat taaatggatg atggatactg aagatttttc tctacggaca
      781 ccaagttatt tctaccagca ggcagtgccc acttcaaact caaccattgt gattttcttg
      841 gcatttacaa actacatcct tacactgtta ttaggagata gcaaacaagg atcttcccgg
      901 cctctgtgac attcaccgag ctctcacaca gccactgcta ctcctatcga gatgtacatt
      961 caaggtacat cagaactctc atttcttccc cttcctttcc taaaccttct ctcttccttt
     1021 ccccctttgc cattcacctt tactatcacc tcccacctcc attatcacct ccccattgcc
     1081 acacaacctc tccctgtaga gaggcaggag gtccttcgaa gctttgcccc atgcgtcaga
     1141 tggcacctga ggcatataac ctagggtggg ctgcctttca ggatccgtca tcaaagggag
     1201 tcaaacatag tcaagatacc atctaccctg tacagctttc ttgagacttg ggggcctggg
     1261 tcaaagagat ttgtctgtcc cttgctgccc atctttaagt aataaaccga cttcacataa
//
