LOCUS       NM_024615               7475 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens poly(ADP-ribose) polymerase family member 8 (PARP8),
            transcript variant 2, mRNA.
ACCESSION   NM_024615 XM_938829 XM_943884 XM_943889 XM_943891
VERSION     NM_024615.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7475)
  AUTHORS   Vyas,S., Matic,I., Uchima,L., Rood,J., Zaja,R., Hay,R.T., Ahel,I.
            and Chang,P.
  TITLE     Family-wide analysis of poly(ADP-ribose) polymerase activity
  JOURNAL   Nat Commun 5, 4426 (2014)
   PUBMED   25043379
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7475)
  AUTHORS   Viding,E., Price,T.S., Jaffee,S.R., Trzaskowski,M., Davis,O.S.,
            Meaburn,E.L., Haworth,C.M. and Plomin,R.
  TITLE     Genetics of callous-unemotional behavior in children
  JOURNAL   PLoS One 8 (7), e65789 (2013)
   PUBMED   23874384
  REMARK    Erratum:[PLoS One. 2013;8(7). doi:
            10.1371/annotation/0b16418f-ceb5-41b2-be2a-a20f0c56f9a6]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7475)
  AUTHORS   Fan,Q., Barathi,V.A., Cheng,C.Y., Zhou,X., Meguro,A., Nakata,I.,
            Khor,C.C., Goh,L.K., Li,Y.J., Lim,W., Ho,C.E., Hawthorne,F.,
            Zheng,Y., Chua,D., Inoko,H., Yamashiro,K., Ohno-Matsui,K.,
            Matsuo,K., Matsuda,F., Vithana,E., Seielstad,M., Mizuki,N.,
            Beuerman,R.W., Tai,E.S., Yoshimura,N., Aung,T., Young,T.L.,
            Wong,T.Y., Teo,Y.Y. and Saw,S.M.
  TITLE     Genetic variants on chromosome 1q41 influence ocular axial length
            and high myopia
  JOURNAL   PLoS Genet 8 (6), e1002753 (2012)
   PUBMED   22685421
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112187.2, DC417471.1, DC429180.1, AL834477.1 and AC022441.5.
            
            On Nov 22, 2018 this sequence version replaced NM_024615.3.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein (isoform 1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.193309.1,
                                           SRR1803617.263938.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000281631.10/ ENSP00000281631.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-301               AC112187.2         90454-90754
            302-847             DC417471.1         1-546
            848-921             DC429180.1         519-592
            922-3298            AL834477.1         580-2956
            3299-7475           AC022441.5         115431-119607       c
FEATURES             Location/Qualifiers
     source          1..7475
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q11.1"
     gene            1..7475
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /note="poly(ADP-ribose) polymerase family member 8"
                     /db_xref="GeneID:79668"
                     /db_xref="HGNC:HGNC:26124"
     exon            1..550
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     CDS             460..3024
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /EC_number="2.4.2.30"
                     /note="isoform 1 is encoded by transcript variant 2;
                     ADP-ribosyltransferase diphtheria toxin-like 16; protein
                     mono-ADP-ribosyltransferase PARP8"
                     /codon_start=1
                     /product="protein mono-ADP-ribosyltransferase PARP8
                     isoform 1"
                     /protein_id="NP_078891.2"
                     /db_xref="CCDS:CCDS3954.1"
                     /db_xref="GeneID:79668"
                     /db_xref="HGNC:HGNC:26124"
                     /translation="MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYV
                     GGPRSVSYSVHVSEDYPDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCC
                     LSIKSKLQKENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSA
                     VREIYGPHAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQ
                     YLNGPVPTVDVFQISTKERFGLGHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKV
                     KSPLHLFSTLRRSPSYPPPGCGKSKSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVT
                     KSHRTFGRSLSSDPRAEQAMTAIKSHKLLNRPCPAAVKSEECLTLKSHRLLTRSCSGD
                     PRCEHNTNLKPHKLLSRSYSSNLRMEELYGLKNHKLLSKSYSSAPKSSKTELFKEPNA
                     EGRRLSLTSGLIGILTPSSSSSSQLAPNGAKCIPVRDRGFLVQTIEFAEQRIPVLNEY
                     CVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCR
                     SALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYL
                     EIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESN
                     FRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSIS
                     FGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSD
                     LHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIHKEILRVIGNQTATG"
     exon            551..605
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            606..643
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            644..733
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            734..804
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            805..882
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            883..977
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1038
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1129
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1196
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1322
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1887
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..1938
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            1939..2034
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2035..2127
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2128..2253
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2254..2319
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2320..2387
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2436
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2437..2549
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2550..2622
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2623..2692
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2693..2766
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2767..2836
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2837..2921
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     exon            2922..7475
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3279..3284
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /note="hexamer: AATAAA"
     polyA_site      3297
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /note="major polyA site"
     regulatory      7452..7457
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /note="hexamer: AATAAA"
     polyA_site      7475
                     /gene="PARP8"
                     /gene_synonym="ARTD16; pART16"
                     /note="major polyA site"
ORIGIN      
        1 gtggaaggcc ggcgtgcgag ccgtgagggg tgtgcgcgcg tgagccggag cggggctcgc
       61 ccctcgccgg cgcccgccgc ccagccggtg attgctctct ggctgtcccc ggcacctcgg
      121 cccccacggc cgttggtccg ggcgggtgag ggagaaagtg agacttggtg tcatcaccat
      181 ccattgtcag aaggggagga aattggaatc cagcagcggc gagcagcagc tgggcggtca
      241 catctgggaa tgcaaagccg acctccccct cctcctcctc ctccccctcc tcctcctcct
      301 cttctctcac ccaggatcac ttccgaaacc acttcgcctt cagcccctgc ctcggccaga
      361 ggtttcattt ttaactgaat atttacgaaa gctggaagcg tgcgaggggg gtggggtggg
      421 gtggaaatag cggctgcttc ttttccaggg atttatttaa tggggatgtg ttcaaggcaa
      481 gagcgaattc agaaggatat cgacgtcgtg atccagaagt ccagagctga gaaggactgc
      541 ctgtttgcag atttcagata ctctgactcc acctttactt ttacctacgt tggcggcccc
      601 agaagtgtat cctactcagt acatgtatct gaagattacc cagataatac atatgtgtca
      661 agttcagaga atgatgaaga tgtgctagtt actacagagc caataccagt aatttttcat
      721 agaatagcaa cagaattaag aaaaacaaat gacattaact gttgcttatc cataaaatcc
      781 aaattacaaa aggaaaatgg ggaggaatca agacagaata gtacagtgga ggaagattct
      841 gaaggtgaca atgattccga agaattttat tacggagggc aggtgaacta tgatggggaa
      901 ctgcacaagc acccacaact ggaagctgat ttgtcagcag ttagagagat atatgggcca
      961 catgcagttt ctctcaggga atatggagcc attgatgatg tagatattga tctgcatatc
     1021 gatgttagct ttcttgatga ggagattgct gtggcttggg aagtaattcg aacagaacct
     1081 ataattgttc gactacactg ttcacttaca cagtatttaa atggcccagt gcccactgtt
     1141 gatgtctttc agatttccac aaaagagcga tttggattgg gacatcagct gaaaaaaatc
     1201 atgcagacat ttgttacaca gcagtggaaa cagagcaaag aaaaatccaa ttgcctgcac
     1261 aataaaaagt tgtcagagaa gaaagtgaag tctcccctgc atttattttc tactttgcgc
     1321 aggtcgccaa gttatcctcc ccctggttgt ggcaaaagca aatccaaact gaaatctgag
     1381 caggacggaa tctccaaaac gcataagctg ctgcggagga cttgttccag cacagtcaag
     1441 actgatgatg tgtgtgtcac aaagtcacac aggacctttg gccgctcctt gtccagcgat
     1501 cccagggcgg agcaggctat gacagcaatt aaatcgcaca aacttttgaa ccgtccttgc
     1561 cctgcagctg ttaagtcaga ggaatgccta actctaaagt cgcatagact attgactcga
     1621 tcttgttctg gagatccacg atgtgagcac aacacaaact tgaagcccca taaactgtta
     1681 agcaggtctt actctagtaa tctcagaatg gaagaattat atggactgaa aaatcacaaa
     1741 ttgctcagca agtcctactc cagtgccccc aagtcatcca aaactgagct tttcaaggaa
     1801 cctaacgcag agggcaggag gctctctctt acctcagggc ttattggtat cctaacacca
     1861 tcttcatctt catcttctca gcttgctcca aatggtgcaa aatgcattcc agtacgagac
     1921 cgtggcttcc tggtgcagac aattgagttt gctgaacagc ggatccctgt attaaatgaa
     1981 tattgtgtgg tttgtgatga gccacatgtg tttcaaaatg gccctatgct taggcctacc
     2041 gtatgtgaac gggagctgtg tgtgtttgct tttcaaaccc tgggagtaat gaatgaagct
     2101 gctgatgaaa tagcaactgg agctcaggtg gtagatctac tagtatccat gtgtaggtct
     2161 gcgttggaat ctcctagaaa agttgtgatt ttcgagccat atccttctgt ggtagatcct
     2221 aatgatcctc agatgttggc cttcaacccc aggaaaaaga actatgatcg agtaatgaaa
     2281 gcactggata gcataacttc tatcagagaa atgacacaag caccatatct ggaaatcaag
     2341 aagcaaatgg ataaacagga cccccttgct catcccttac tgcaatgggt tatatcaagt
     2401 aatagatcac atattgtgaa actgccagtt aacaggcaat tgaagtttat gcatactcca
     2461 catcagttcc ttcttctcag cagtccacca gccaaagaat ccaattttag agctgctaaa
     2521 aaactctttg gaagcacctt tgcatttcat ggctcacaca ttgaaaactg gcactccatc
     2581 ctgaggaatg gtctggttgt tgcttctaat acacgattgc agctccatgg tgcaatgtat
     2641 ggaagtggaa tctatcttag tccaatgtca agcatatcat ttggttactc agggatgaac
     2701 aagaaacaga aggtgtcagc caaggacgag ccagcttcaa gcagtaaaag cagcaataca
     2761 tcacagtcac agaaaaaagg acagcaatcc caattcctgc aaagccgtaa cttaaaatgc
     2821 atagccttat gtgaagtgat cacctcatct gacctgcaca aacatggaga gatatgggtt
     2881 gtccccaata ctgaccatgt ctgcacacga ttctttttcg tctatgaaga cggccaagtg
     2941 ggagatgcaa atattaatac acaagaagga ggcattcaca aagagatcct ccgagtaatt
     3001 ggtaatcaaa ctgctactgg ttaaaggacc accatttaat taacatgatt cgaaagcctt
     3061 cctcgggttc aaagctggat tttgaactga agaagattat aaaattattt attgttatta
     3121 taaacaaaat taaccctttg aatactgatt ttttttctta gtatttctaa gtatctcatt
     3181 aaatacctaa aatggtataa gatttatcaa ttgtagggtt atggaatcta gtaataaaat
     3241 ttcaacagca cttaaactga agtttgggtt gctcatacaa taaacagatt gaaaaaactg
     3301 ttttgtgctg atatttttat actaaactct ttaactggat atttggtatt atataccgac
     3361 attttaggtt accaaaatag aattgagaac attttataat ggcatctaaa tctatcagat
     3421 actttgcaat aagtatactg tttgcacatt ctgatgtgct atatcattag tagtatgggc
     3481 attctaatgt tttggaaggg gtgttcccta ttctattttt cttcataaaa aaagaagtag
     3541 gtcttagaag cagtgctttg ccaaaaagta tgtaatatac acatctatac attcatgcat
     3601 caaaatgtgt ggttgtgaat atatttgtgt atattcacac gtatgttttg acaagaaaga
     3661 tggcttagct tcacaattct atcctcgttt aatggaaaga agataatatt tagtaagcaa
     3721 taaatttgga cataaatcaa gatatgagcc agatttacca ccattcattc actgaaaata
     3781 tttgcagaca atttttctgt ttgtctgaag aaattcagcc cttttaaaat gttatctaaa
     3841 agtcataatt tggggaacat acatggcctg gtagaccgaa tctatattca aatgattatg
     3901 tatttaaaag aaagacctca gaatttaaag aaaccatata tattttttat ttactacaaa
     3961 aaaattatac aattttattt atgccacacc agcattttta tatttgttca tctaatatct
     4021 ctgcttattt ttttcatatt gagaaagaac acaaacttga tgcttctttt atattaaaag
     4081 accacaaata agtttataga gaacagtaac accagctctc agcatttcct tttcaagagt
     4141 cataatttca tcaaaatcat ttcttattct ttgagtccta gagttcttat tcatcaagtt
     4201 ttaattgaca gtgtttattt tcccacatgt tgtctttgga ataaggccat tcatgaaagc
     4261 agtttaatta gtgagtctgc cactctattc aaaccctgaa tcaaggctct atctgatttt
     4321 aatttatgta aaaaaaaata aaaatgtata gtcatttgca agtataatgt gataactgct
     4381 gtgtttattt cctttgtctg gcataaaagg tgagaaaaag gtcatacatg ttgttaaggg
     4441 tagcagttta ggaagtgttt tctaataatt tgttttgtta tattgcaaat aattgatatg
     4501 ccacttattt ctgcaagaaa aataggcttg aagtggttgg gatattaatc attttgatag
     4561 tatctactta aagcattgat ctgttttgac ttgtggctct gaaccctggg ctaggctgag
     4621 ggataatagt agtggagtag ggcaaagata taatatccta tccagtgttt tgtgaccact
     4681 tatttgaaga ttagtgtggg acatgaggac cttgctactt ttttgccaag atgctgcaag
     4741 tctcccaaat cacttcaact gtgtttttaa aacatgttta agcaacagaa ttattttttt
     4801 gaaattagtc tatacgttag acagtctata catgacaaac atgaagatct aatatcaaga
     4861 tttgggagac gggatcttgg aactccacct gtttgaccac taggaccact gaggcacctc
     4921 caataagctc tgtagagtgc ctccagcata attcaaaatc cactgaccta atccattatg
     4981 gctttactta acattggagt gatccgtaaa gaatatagta ttggagtctg aactggaacg
     5041 gtaactcgta agactcaaga aagaccgttt aaggaaaatt ggcataatac aaactgttcc
     5101 tgttgactta agaataacag taggttcacc tatctgagga aattaagtag ttgatagttt
     5161 aatgctaggc atcttttatg ataataaagt aagatgtctt cttatgacag ttaattgagt
     5221 tgtatcatga tacagaatga cagattttgt ttcaaacaat tgcgtcagaa cctttgtaag
     5281 caaatattct aaggagaatc aatcttattt tttaattgaa ctttttgaaa ttagggatac
     5341 tataataact gataaagatg aatttctgtg tttctaaaga atctaatttc aattactacc
     5401 attaacatat aaatgtgctt ccaaaatcca agcaggtcca tacaatttag agatttgaac
     5461 actgttatca tgctttaatt cagtcattca ttaaaatatt atctattcac ttatttgatg
     5521 attccaaaca tttgatattg tattgtgttt ttataattat ttgaaatctg ttcaccaatg
     5581 ctttgtaatg gttttattaa ttgtgtagcc attgctactt agatagtaac ccactgagca
     5641 aaggcagtca tttattttca tccttgaagt aggggaagaa aattattaat ttattagttc
     5701 tactttttcc tgcattgctt attttgtaaa cattttacta tgaataatct gttctctttc
     5761 actgtattaa aaggagaaga aaatgaacat ttgagaatgg aaaaaagtaa taatatacaa
     5821 ataatctagt gctataaaat gcattatagt aagacacttt tggtgtcttc gagtgcacta
     5881 tgttggaata aattttatac ttgttgctta gtaaatctca gtcatacgtt tggtttgaag
     5941 ctgttttttt ttttaatttg aagtttaatt ttaaaagtgc cacattgtaa aagttaccgt
     6001 taaatactat gtagtataaa aaaccaaccc aagctattgt taatgctctg aatgtttttc
     6061 tttgaaaatt taagtttaga gaagaaattc cttcattttt ctcccctttg ctaaaagaaa
     6121 gaaaatctat aatatgtaag tctatgaatc tttaaataac tgaaggaatt ttagcagtac
     6181 tttgtataat aaaaatattt tttaaactat aacttgcctt agagcatggg gtttcagaaa
     6241 gttttgacga aaaactcatc ttcattaaag agtctggata acttcatcag atggtaattt
     6301 aatatgtcat gaaggggaca ctcaacattg ggtcatctac cgtctaaata aatacggatt
     6361 tcatggtggc atttgaagca cattttgcaa acattatgat gttctattgt cttgctgaat
     6421 tctttattat aacactacct caagacaaat gatagactgt tggtaaggta aattgggttt
     6481 tcaatgtcag gaacaaataa aattttgcaa atagaagtca tcaaataatt caacaggaag
     6541 accatactgg acacagatgt tgtcagttac ttctggacaa tgtggtaaca tggatatttc
     6601 agtcactggt aacaatgtca gggttaacac ccaatgaatt atttgaaaca atttgggttg
     6661 caaaatttga aattaattag tctattttga gattgatttt ctacgtgggc caattttatg
     6721 tccattacct aaagccacaa tctcccgctc taaggagtta aaggatgaaa acacccaact
     6781 gctacactgg aatggcagac tggatattca agcattttgg catttaatgc ctgctaaatt
     6841 tttgtccgat tatatataga tttgatgtat attattaccc agtaaattct tcttgggaat
     6901 tttgtataca ttatggaata ttaggataag tttttgtagg tcagaagaat ttcaagtagt
     6961 ttttagacaa aacatatcca tgagtgtgaa aaaagctgtg ttgacgaata gattacattt
     7021 cacatttacc agcaagtcag taaaaaatag tgcttattta catagtcaat ataatttaat
     7081 gttctaaaaa taatatcttc gatctgccca atatttaatg tatcatttga gatttttaaa
     7141 aatgcatccg ctccattatg taaacattaa gatatgccta tgtttcttta actatacagc
     7201 ctctttacaa taaatttctt gatttttgtg cacaggatag tattgcaacc tgctatttag
     7261 cctttggtgc cttagaatta ttataaatat ttaacaatat gtacataatg taaatactgc
     7321 caagagatca gtaaggccaa atattttctc tattcacttt ttattgctct tgctttctat
     7381 tgctactaaa gcctctttta tccagctttg taatagttcc aacattgtag cgaatgtaaa
     7441 tgtttacttt caataaatct gaacttgttc aacaa
//
