LOCUS       XM_047434182            1924 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens poly(A)-specific ribonuclease (PARN),
            transcript variant X2, mRNA.
ACCESSION   XM_047434182
VERSION     XM_047434182.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1924
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..1924
                     /gene="PARN"
                     /gene_synonym="DAN; DKCB6; PFBMFT4"
                     /note="poly(A)-specific ribonuclease; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 46
                     ESTs, 417 long SRA reads, and 95% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     14 samples with support for all annotated introns"
                     /db_xref="GeneID:5073"
                     /db_xref="HGNC:HGNC:8609"
                     /db_xref="MIM:604212"
     CDS             136..1908
                     /gene="PARN"
                     /gene_synonym="DAN; DKCB6; PFBMFT4"
                     /codon_start=1
                     /product="poly(A)-specific ribonuclease PARN isoform X2"
                     /protein_id="XP_047290138.1"
                     /db_xref="GeneID:5073"
                     /db_xref="HGNC:HGNC:8609"
                     /db_xref="MIM:604212"
                     /translation="MEIIRSNFKSNLHKVYQAIEEADFFAIDGEFSGISDGPSVSALT
                     NGFDTPEERYQKLKKHSMDFLLFQFGLCTFKYDYTDSKYITKSFNFYVFPKPFNRSSP
                     DVKFVCQSSSIDFLASQGFDFNKVFRNGIPYLNQEEERQLREQYDEKRSQANGAGALS
                     YVSPNTSKCPVTIPEDQKKFIDQVVEKIEDLLQSEENKNLDLEPCTGFQRKLIYQTLS
                     WKYPKGIHVETLETEKKERYIVISKVDEEERKRREQQKHAKEQEELNDAVGFSRVIHA
                     IANSGKLVIGHNMLLDVMHTVHQFYCPLPADLSEFKEMTTCVFPRLLDTKLMASTQPF
                     KDIINNTSLAELEKRLKETPFNPPKVESAEGFPSYDTASEQLHEAGYDAYITGLCFIS
                     MANYLGSFLSPPKIHVSARSKLIEPFFNKLFLMRVMDIPYLNLEGPDLQPKRDHVLHV
                     TFPKEWKTSDLYQLFSAFGNIQISWIDDTSAFVSLSQPEQVKIAVNTSKYAESYRIQT
                     YAEYMGRKQEEKQIKRKWTEDSWKEADSKRLNPQCIPYTLQNHYYRNNRQGLILLPRL
                     ECSGTITACCSFDLLGSSDPPTST"
ORIGIN      
        1 gtttccggaa gtcgcggccg gcgtcaccgc tgcggctgcc tcagctactg ccgcagtcgc
       61 cgcggaattc ggcgagtaga accgctgagg cgggcgcggg cccgggtggg gccaaggttc
      121 cggccactct gcagaatgga gataatcagg agcaatttta agagtaatct tcacaaagtg
      181 taccaggcca tagaggaggc cgacttcttc gccatcgatg gggagttttc aggaatcagt
      241 gatggacctt cagtctctgc attaacaaat ggttttgaca ctccagaaga gaggtatcag
      301 aagcttaaaa agcattccat ggactttttg ctatttcagt ttggcctttg cacttttaag
      361 tatgactaca cagattcaaa gtatataacg aagtcattta acttctatgt tttcccgaaa
      421 cccttcaata gatcctcacc agatgtcaaa tttgtttgtc agagctccag cattgacttt
      481 ctagcaagcc agggatttga ttttaataaa gtttttcgaa atggaattcc atatttaaat
      541 caggaagaag aaagacagtt aagagagcag tatgatgaaa aacgttcaca ggcgaatggt
      601 gcaggagctc tgtcctatgt atctcctaac acttcaaaat gtcctgtcac gattcctgag
      661 gatcaaaaga agtttattga ccaagtggta gagaaaatag aggatttatt acaaagtgaa
      721 gaaaacaaga acttggattt agagccatgt accgggttcc aaagaaaact aatttatcag
      781 actttgagct ggaagtatcc gaaaggcatt catgttgaga ctttagaaac tgaaaagaag
      841 gagcgatata tagttatcag caaagtagat gaagaagaac gcaaaagaag agagcagcag
      901 aaacatgcca aagaacagga ggagctgaat gatgctgtgg gattttctag agtcattcac
      961 gccattgcta attcgggaaa acttgttatt ggacacaata tgctcttgga cgtcatgcac
     1021 acagttcatc agttctactg ccctctgcct gcggacttaa gtgagtttaa agagatgaca
     1081 acatgtgttt tccccagact cttggatact aaattgatgg ccagcacaca accttttaag
     1141 gatatcatta acaacacatc ccttgcggaa ttggaaaagc ggttaaaaga gacacctttc
     1201 aaccctccta aagttgaaag tgccgaaggt tttccaagtt atgacacagc ctctgaacaa
     1261 ctccacgagg caggctacga tgcctacatc acagggctgt gcttcatctc catggccaat
     1321 tacctaggtt cttttctcag ccctccaaaa attcatgtgt ctgccagatc aaaactcatt
     1381 gaaccttttt ttaacaagtt atttcttatg agggtcatgg atatccccta tctaaacttg
     1441 gaaggaccag acttgcagcc taaacgtgat catgttctcc atgtgacatt ccccaaagaa
     1501 tggaaaacca gcgaccttta ccagcttttc agtgcctttg gtaacattca gatatcctgg
     1561 attgatgaca catcagcatt tgtttccctt agccagcccg agcaagtaaa gattgctgtc
     1621 aataccagca aatatgcaga aagctatcgg atccaaacct atgctgaata tatggggaga
     1681 aaacaggaag agaagcagat caaaagaaag tggactgaag atagctggaa ggaggctgac
     1741 agcaaacggt taaaccccca gtgcataccc tacaccctgc agaatcacta ttaccgcaac
     1801 aatagacagg gtctcattct gttgcccagg ctggagtgca gtggcacaat cacagcttgc
     1861 tgcagcttcg acctcctggg ctcaagtgat cctccaacct caacctgagt agctggcact
     1921 acag
//
