LOCUS       NM_198504               9090 bp    mRNA    linear   PRI 09-JUN-2024
DEFINITION  Homo sapiens progestin and adipoQ receptor family member 9 (PAQR9),
            transcript variant 1, mRNA.
ACCESSION   NM_198504 XM_293613
VERSION     NM_198504.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9090)
  AUTHORS   Lin,Y., Chen,L., You,X., Li,Z., Li,C. and Chen,Y.
  TITLE     PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during
            fasting by modulating protein stability of PPARalpha
  JOURNAL   Mol Metab 53, 101331 (2021)
   PUBMED   34474167
  REMARK    GeneRIF: PAQR9 regulates hepatic ketogenesis and fatty acid
            oxidation during fasting by modulating protein stability of
            PPARalpha.
REFERENCE   2  (bases 1 to 9090)
  AUTHORS   You,X., Lin,Y., Hou,Y., Xu,L., Cao,Q. and Chen,Y.
  TITLE     PAQR9 Modulates BAG6-mediated protein quality control of
            mislocalized membrane proteins
  JOURNAL   Biochem J 477 (2), 477-489 (2020)
   PUBMED   31904842
  REMARK    GeneRIF: the polyubiquitination of MLPs is enhanced by PAQR9 PAQR9
            binds to the DUF3538 domain within the proline-rich stretch of
            BAG6. PAQR9 reduces the binding of MLPs to BAG6 in a DUF3538
            domain-dependent manner. Taken together, our results indicate that
            PAQR9 plays a role in the regulation of protein quality control of
            MLPs via affecting the interaction of BAG6 with membrane proteins.
REFERENCE   3  (bases 1 to 9090)
  AUTHORS   Pang,Y., Dong,J. and Thomas,P.
  TITLE     Characterization, neurosteroid binding and brain distribution of
            human membrane progesterone receptors delta and {epsilon} (mPRdelta
            and mPR{epsilon}) and mPRdelta involvement in neurosteroid
            inhibition of apoptosis
  JOURNAL   Endocrinology 154 (1), 283-295 (2013)
   PUBMED   23161870
  REMARK    GeneRIF: The results suggest that PAQR6 and PAQR9 (mPRdelta and
            mPRepsilon) function as mPRs coupled to G proteins and are
            potential intermediaries of nonclassical antiapoptotic actions of
            neurosteroids in the central nervous system.
REFERENCE   4  (bases 1 to 9090)
  AUTHORS   Demirkan,A., van Duijn,C.M., Ugocsai,P., Isaacs,A.,
            Pramstaller,P.P., Liebisch,G., Wilson,J.F., Johansson,A., Rudan,I.,
            Aulchenko,Y.S., Kirichenko,A.V., Janssens,A.C., Jansen,R.C.,
            Gnewuch,C., Domingues,F.S., Pattaro,C., Wild,S.H., Jonasson,I.,
            Polasek,O., Zorkoltseva,I.V., Hofman,A., Karssen,L.C.,
            Struchalin,M., Floyd,J., Igl,W., Biloglav,Z., Broer,L., Pfeufer,A.,
            Pichler,I., Campbell,S., Zaboli,G., Kolcic,I., Rivadeneira,F.,
            Huffman,J., Hastie,N.D., Uitterlinden,A., Franke,L., Franklin,C.S.,
            Vitart,V., Nelson,C.P., Preuss,M., Bis,J.C., O'Donnell,C.J.,
            Franceschini,N., Witteman,J.C., Axenovich,T., Oostra,B.A.,
            Meitinger,T., Hicks,A.A., Hayward,C., Wright,A.F., Gyllensten,U.,
            Campbell,H. and Schmitz,G.
  CONSRTM   DIAGRAM Consortium; CARDIoGRAM Consortium; CHARGE Consortium;
            EUROSPAN consortium
  TITLE     Genome-wide association study identifies novel loci associated with
            circulating phospho- and sphingolipid concentrations
  JOURNAL   PLoS Genet 8 (2), e1002490 (2012)
   PUBMED   22359512
REFERENCE   5  (bases 1 to 9090)
  AUTHORS   Smith,J.L., Kupchak,B.R., Garitaonandia,I., Hoang,L.K., Maina,A.S.,
            Regalla,L.M. and Lyons,T.J.
  TITLE     Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in
            yeast confirms their ability to function as membrane progesterone
            receptors
  JOURNAL   Steroids 73 (11), 1160-1173 (2008)
   PUBMED   18603275
  REMARK    GeneRIF: PAQR9 is a previously uncharacterized PAQR which is also
            capable of responding to progesterone.
REFERENCE   6  (bases 1 to 9090)
  AUTHORS   Tang,Y.T., Hu,T., Arterburn,M., Boyle,B., Bright,J.M., Emtage,P.C.
            and Funk,W.D.
  TITLE     PAQR proteins: a novel membrane receptor family defined by an
            ancient 7-transmembrane pass motif
  JOURNAL   J Mol Evol 61 (3), 372-380 (2005)
   PUBMED   16044242
REFERENCE   7  (bases 1 to 9090)
  AUTHORS   Piddington,R.
  TITLE     Subcellular distribution of glutamyltransferase activities in
            embryonic cerebral hemispheres
  JOURNAL   Brain Res 128 (3), 505-514 (1977)
   PUBMED   18257
REFERENCE   8  (bases 1 to 9090)
  AUTHORS   Gilbert,J.C. and Wyllie,M.G.
  TITLE     Synaptosome transmitter release and ATPase activity [proceedings]
  JOURNAL   Br J Pharmacol 60 (2), 300P-301P (1977)
   PUBMED   18252
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC021074.15.
            
            On Oct 23, 2019 this sequence version replaced NM_198504.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK123932.1, AY424287.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000340634.6/ ENSP00000341564.4
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9090              AC021074.15        35016-44105
FEATURES             Location/Qualifiers
     source          1..9090
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q23"
     gene            1..9090
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
                     /note="progestin and adipoQ receptor family member 9"
                     /db_xref="GeneID:344838"
                     /db_xref="HGNC:HGNC:30131"
                     /db_xref="MIM:614580"
     exon            1..9090
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
                     /inference="alignment:Splign:2.1.0"
     CDS             339..1472
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     progestin and adipoQ receptor family member IX; mPR
                     epsilon; membrane progesterone receptor epsilon; membrane
                     progesterone P4 receptor epsilon; progesterone and adipoQ
                     receptor family member 9; membrane progestin receptor
                     epsilon; brown fat long noncoding RNA"
                     /codon_start=1
                     /product="membrane progestin receptor epsilon isoform 1"
                     /protein_id="NP_940906.1"
                     /db_xref="CCDS:CCDS3128.1"
                     /db_xref="GeneID:344838"
                     /db_xref="HGNC:HGNC:30131"
                     /db_xref="MIM:614580"
                     /translation="MPRRLQPRGAGTKGPPAPAPAASGAARNSHSAASRDPPASAKPL
                     LRWDEVPDDFVECFILSGYRRLPCTAQECLASVLKPTNETLNFWTHFIPLLLFLSKFC
                     RLFFLSGGDVPFHHPWLLPLWCYASGVLLTFAMSCTAHVFSCLSLRLRAAFFYLDYAS
                     ISYYGFGSTVAYYYYLLPGLSLLDARVMTPYLQQRLGWHVDCTRLIAAYRALVLPVAF
                     VLAVACTVACCKSRTDWCTYPFALRTFVFVMPLSMACPIMLESWLFDLRGENPTLFVH
                     FYRRYFWLVVAAFFNVSKIPERIQPGLFDIIGHSHQLFHIFTFLSIYDQVYYVEEGLR
                     QFLQAPPAAPTFSGTVGYMLLLVVCLGLVIRKFLNSSEFCSKK"
     regulatory      2414..2419
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
                     /note="hexamer: AATAAA"
     polyA_site      2437
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
                     /note="major polyA site"
     polyA_site      7250
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
     regulatory      9070..9075
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
                     /note="hexamer: AATAAA"
     polyA_site      9090
                     /gene="PAQR9"
                     /gene_synonym="BLNC1"
ORIGIN      
        1 agtcaccgct gccgcgctgc cgccgcagtc agccgcgccg ccgccgctgc cgcagcgcgg
       61 gcggccgcgc gccggtagca ggggcttggc gaggaagccg ctgagcctcg cgcgctccgc
      121 gctcctggcg gtcgcagcgc tgcctattaa ttgattctct tattgattta tttaattttt
      181 aggagcggct gctcggaggc acgggtcttc tcctaaacct gcagcgacgc ccccggcgtg
      241 ggcacaaagg ctccgacggc ggccggcggg ggctgcccag cgcccgggag ccggcgccag
      301 aggtcgcctg cgcgcgccct agccgagccc cgggcaccat gccgcggcgc ctgcagcccc
      361 ggggcgcggg cacaaaaggc cctccggccc cggccccggc agcttcgggg gccgcccgga
      421 actcccactc tgccgcctcc cgggaccccc cagcgtctgc caagccgctg ctgcgctggg
      481 acgaggtgcc cgacgacttc gtggagtgct tcatcctgtc gggctaccgg cgtctgccgt
      541 gcacggccca ggagtgccta gcctcggtgc tgaagcctac caacgagacg ctcaacttct
      601 ggacgcactt catcccgctg ctgctgttcc tgagcaagtt ctgccgtctg ttcttcctga
      661 gcggcggcga cgtgcccttc caccacccgt ggctgctacc gttgtggtgc tacgcgtcgg
      721 gagtgctgct gaccttcgcc atgagctgca cggcgcacgt gttcagctgc ctgtcgctgc
      781 gtctgcgcgc cgccttcttc tacctggact acgcgtccat cagctactac ggcttcggca
      841 gcacggtggc ctactactac tacctgttgc caggcctcag cttgctggat gccagagtca
      901 tgactccata cttgcagcag cgcctgggct ggcacgtgga ctgcacgcgc cttatcgccg
      961 cctaccgcgc cctggtgctg cctgtggcct tcgtgctggc ggtggcttgc actgtggcct
     1021 gctgcaagag ccgtaccgac tggtgtacct acccgttcgc gctgcgcacc ttcgtcttcg
     1081 tcatgccgct cagcatggcc tgccccatta tgctcgagag ctggctcttc gacctgcgtg
     1141 gggagaaccc cacactcttc gtgcacttct accgccgcta cttctggctg gtggtggccg
     1201 ccttcttcaa cgtgagcaag atccccgagc gcatccagcc gggtcttttc gacattatcg
     1261 gccacagcca ccagctcttc cacatcttca ccttcctcag catctacgac caggtgtact
     1321 acgtagaaga gggcctgcgc cagttcctcc aggcgccgcc tgccgcaccc actttctcgg
     1381 gtactgtggg ctacatgctg ctgctggtgg tctgcctggg gctggtaatc aggaagttcc
     1441 taaacagctc cgaattctgc agtaaaaagt gagcctccgc cttggaggag actactggtt
     1501 cgcccatctg tttggagttt ctgttgttgc tattgttggt ttgttttcaa atttcattgt
     1561 gttttcttct ttgctcaagg aaggtgctgc aaaaccatag ggaaaaagtt cactgctaca
     1621 aagggatccc aacccactgg aggctttgaa gtagggaggt tggcaggggt ggtcaagcgg
     1681 gagggagata gtcacttgtt cttgcccctg gaaaaaattc aggtgatgtc tttgacatcc
     1741 agggatttct caaaggcagt gagtaaaatc ccaaataaag ccccaaagag tttgcttttc
     1801 caatcatctg tgccattggt aataaggagt agcccctgtg aggtcaggta cacagtaaag
     1861 agggtaaata gaatccttgg gaacttctgt ttcagtctga ggaatgcttg gatttgtcaa
     1921 aagaatggag ctttgtagga aacaggcaca aagacgcaaa cccagggctt aacctgctag
     1981 aaaatgcatg gaatgtgaac acaagttaat tatttcaaaa tgtttttcag atgttattta
     2041 aatagtaata tatacattga tttttcataa tttatcaaag cctgtggtac gcactgaatt
     2101 ttctttgtca catagttttg aatttcacag ccttctgcat tgcatacact tgaactggac
     2161 atcaggggaa gctgcttgag agttctcaat tactttctta aacagtgttt tctgaaggcg
     2221 tgtgtcatga tacaactgtg aattctacct tagggactct ggttaaacta ttggtgagga
     2281 gctcgagtgg tttgtataga ccccagattt ttgtttactt taatgtattc cacaaaaccc
     2341 atcctggttt ttgttagttt gttttgtttt taatcttttt ttttccttct ctacttattt
     2401 aaattgccac tggaataaat gtgccttttg aagcaaagtc caaatgactg gtcctcaaac
     2461 acagtttctt acatggggag agtagtaaga ataagctttt cttacctgac tgaaaatcaa
     2521 ggtttcatgg tccatccagg agggcagaag atggtgttgg tttcaagttt ttggtgggat
     2581 tggagatagc ttacaggagc gtgcagagca tttgggttcc caacaaggac aaagagccaa
     2641 ccctctaatg tagatgtgtt tctaatgcag ccatgggaga agttctagac tgatgccatc
     2701 catccttgct taaaattaaa aacataatat ccaagaataa acaaggcagt tttattatga
     2761 aaggcaggag cacattattg agttgtcact gaaaattttg agttaaataa gattacactt
     2821 gcctagttaa acgctgaagt ttgatttggt tccagactat ggaaatgatg ggcagtcacc
     2881 ctaaatcctt gaaacattca tgagcatgtc cctgagatcc tttctaacaa acagattagc
     2941 caatgttatt tagacatttc ttacaaatgc taacctgtaa ttgagatggc cactctagat
     3001 taacacaaac cactgagatg acttgtttaa atacttacca cacttcctgg taggtcattt
     3061 tgttagaagc caaataagtc attgattggg agtttttttt gttttgtttt gtttggagac
     3121 atgtgtgcct ttactggctc agcaggagga gtgggtggcc ctcataccca gccagctgta
     3181 cttcactggc ttgtaggtga tggagagctt gcccaggtag tggtggctta tcttgggctt
     3241 gatctccact gcctagttga aggtcttggg caggatgatc atgtcccaca ggtgcatctt
     3301 gattttatga tataacttag atcatgcata tgaggtagat gaacacttac ctcagcactg
     3361 gtaggctggc acttctaaaa caattgctgg ttttgtttat gcttttaatc acttctctgt
     3421 aaacagagaa gctcagcaca attccctgga ggaaccggta tccttgtgtg tgttactttg
     3481 cacatagaag ttaaatttat atatgtctat atttaattta gaatctctta ctgagattgt
     3541 aaatacactt tgcacagttg ttgacgagtg tcagtgtctc atcctttgtg aagtgcaagg
     3601 agattcctgt taggttacag aggctaattt gtacttacaa cagatgttat tcctcagctg
     3661 taacttaatt caatagatgc attcaaggac aactgtggaa atcaggatat ttccacatgc
     3721 aaatttattt gcatgtcatt gttgtttttt ctagagcccc aaagaacatt ggtttggaag
     3781 ctagagaaac agggtgaagc gtattatgta gtttctttgt aaaatgggac ctcaatttca
     3841 gaaggaactt tcaggaggaa gacttctagc aaggattaat gagtttgaga acaataacta
     3901 aaacaccaaa tttgtcattt taattttttg ttgttcttcc aggtccacag acagaattct
     3961 cttcttgtcc tttgtctttg accttaagga gaggccactt aaggataaaa ttatacccat
     4021 atcatttttc aggtgattat gctgcatgag tacagtgaga tgacacactt tttgccacac
     4081 aggtttcagc acccagtatg tcccagagag aatgaggatt cactttcctc ttccctttgc
     4141 cttttccttc gtccactgtt ctttcctatt ccatcttaga ttttgtagac cacatataat
     4201 aatgacaaga ggacattcta gttgaaaact ggtttggctt cacttcatgt ttgcaaatag
     4261 gtaccatata cactagtcaa agccagggat gatttgttaa actatacagt ttatttgctg
     4321 aatttattaa atttcttgat gttttagaag tgaatattta ctttgaatct ccccatttgc
     4381 acggaactat ccaggtttat tacacatttc aaggtaatgt ggcaatcaga acaatatata
     4441 ttttaaaata tttttcacac tttccatttt gccacattaa aattcagttt tactttattg
     4501 tgttcagctg tttgaaatgt aggacaaatt ataaataaga attcagtcca ttatctatgt
     4561 acaacctatt ttggcagtag aattttgaag catattatgt aatatgtttc atttttactt
     4621 gttagtcatg atctggatga catctcaagg agcggcgcca tagagtcatg cctggaaaat
     4681 gaaggtgttt gacttcggtg cctgtcaccc cgtgggttgg tctctggggc tgactcagac
     4741 tgacttagtt ggctaatggg gttcctttct tccctgccgt tcttgcagct caggtgaaga
     4801 ggatgacctt cccagagaga ggaaatgagt tcctcggtca tgtcatgact ggcttgtaaa
     4861 aataaatgtg aacttttcca ctagccatac actttctata aatagcccag ggagaaagta
     4921 tggggctaca gagctggaca gagtggcctt catatgtttc cattcataaa tccagcttgt
     4981 aagtgcttgc agtcaaaaaa caatttagcc taatttatag tgatacttca taggaatcat
     5041 ttctaagaat gcaaaatttt gggacagagg tgatttatat cattttttcc tgatttggtg
     5101 ccaactctga ggactaacag caataataaa caggaatttt tatctttaaa tctcttcata
     5161 actttaatta gttaatctgc acaaagctat aataggagac aggtatggtg ggagttatct
     5221 ccatttcaaa gctttatagt tggtccaagg tgacaggatt aagttttcaa actggcatta
     5281 gaatgcggag accattgtct gctcaactgt gtttactagt ttgcatggct atgatgcctg
     5341 gccaagcaca cagacactaa ttggaaaaag agatatagat acagtccctt aattgactaa
     5401 ctttaaaatt gagcaaagtg agatagggct gtctttgaaa ttagatcaaa atatctcaaa
     5461 caaaatgtta tcagccactt aaaatggttg ttaccatctt gttcttcaac tgttgaagtt
     5521 taccactgct gacttcactc tgtcagcaat ctttgagctg ttcattcatg cactcatatc
     5581 atacctttca tgatctttga gcacctactg tgtgtaagac attgggcaag gacccatccg
     5641 tattattaca gccattaccc ttttgtcttc tggtggaaga gagaagcccc agaaagtctc
     5701 tctggccagg aaccaaactc tgaccttggc tgtaggtaga atgccgtaag tccctgagtt
     5761 tgggtctctt tttttgctag cataagtgca atccatagaa tcttatttct attcacatgc
     5821 tgacttcctc agcaatcaat ttctttcttt tttctttttc tgtgtgctcc taggcctatt
     5881 gttaaaaata acttgaaaat gtaatgtaca atccaagtga ggggatagtc ggcatatgta
     5941 cagaattgaa aaacttatca ctaatattat gaaaacacta ataacgataa ctattggaag
     6001 attgatagta ttcatactat tatgaagagt ggatcatcca aagtgcctaa attgagatgt
     6061 ctttaagtgt ctgaatttta tagtgtaata aaacaaacaa acaaaccaat cacatacata
     6121 agaaggtaaa tggctagatc tccaaaatta actgagatta actaatgctc tctagccttt
     6181 taggatcttt gtgttgtaac ttatgaaaca tgtcttagaa aacattaatc tggaggaaat
     6241 cattaaaaag tgtcagaggt aaaaaagata ggaagaatgc atgggaaggg gagaacaaag
     6301 aggattagag tcaaacagtc agaatggggc agcaagttca actgtgcagt cagcctgagt
     6361 tttaaatttt gtccttagaa aagcatgtga actcccaggg tgttagtgtt cgagtagaca
     6421 ggcaaggaat tctgtttgtc agcttaacca catcttgtag cgtttgacct gagcacgagt
     6481 gtccaggtat attttgagtg gtacatttat ctcctggctt aaagccctta ctttgtttcc
     6541 ataaaattag gacagaggca aaaaggcatt acgggatagc accagccaat tgtacatcac
     6601 cttttgaatc attttcttga aggattgtca atattctctg acatatatca cctgacaaaa
     6661 agcgaacaag cctagacaaa ctgaaaaagg aagcattcag tggttggagc tgagcactac
     6721 tgtgttcttt tgtgagaggc cacacgtttt cttattgaag atttggcttc ttcggtattg
     6781 tgaataatta tttcttaatt gtgaaaatgg atgtcagttc ttcttagtca ctcttccaaa
     6841 agctaatata aatttctgtt gttgtcattt aaaaaaggat aactgtattg catttctggt
     6901 ttgcagattt ctaaccagtt tgtaggcatt tttgttctag agtggctcct taagaatctg
     6961 tgagcaagtt gcagaattag agtgtttatt tataggtcag gggccaagaa tgctcattta
     7021 gctgttaatt gtggcaggat gtgacttttg aaagctctga acatatacct atatgcaaca
     7081 gtatgcacac ttatttacta tttagctcag tggaaaaaca gcctgctctt tgagcttttg
     7141 agaatgtttc ccaatgtatt gtgcttctaa atgtaatgca cttgctttaa tgcttttgtt
     7201 ctcaatcaat ctctggaagc tattccaaac atggcatttc tcaaggaaaa tttcttgaat
     7261 gtgcaaaatt attctccaat gtgtaaaagt gacaggccac ctttccctca tgccttatac
     7321 ctccacccaa aatacgcaat aagcactcaa ggcagaatgg ggggtcttca ggtggtcatt
     7381 tggccgtgct gtaaagatgg ccctgcttct cccagtacac catgatattg aagaaggaca
     7441 ctgtgtaaat aaactcttgt ttctagataa agcatgggga cacaatttca tttcttctta
     7501 gttccatctc tagttggaaa gcataatctg tttttaatat gctggatgca aaaaataaaa
     7561 ttcctgggaa aattttttaa aaaagtattt taattttata tttgtaaagt ttctaataga
     7621 catttgtttg taaaaacagg ccttagcaca taagtgagaa ccagagcttt ttggaaagac
     7681 tcatctttat ccggtgagtt taatcacctt gagctcttac tcaaatgata aagacctagt
     7741 aggtctttaa aaatgtaaat aatgtatagt ttaaagaagg atacaaatca ttttttaaaa
     7801 aagaagaaaa cacatgagat aggttttagg tgtgtctcat ggctaaattt aaaagtcttt
     7861 ttaaaaattc tggttagaaa ctttattaaa ttccctcttc cagcaaaacc tagcacagaa
     7921 ggtctacttt tcaaacaggc tagttttctt ttctggaggc tatgaacaaa attattctcg
     7981 ccaatcaact gagtaccaag gcaataaaga ggtgaggcac ctttcacttt gatgagttta
     8041 taagcatggt gaataacgta gccaataaaa tgtacagccc tggaactctg tcccttgttt
     8101 cttcagaata gaaagaagaa taagccccat gccatcacta tatggaccag aaaaaggctt
     8161 tctgtgtttc agggctgggg gaggattctg tggctgcttt tttttttttt tttttttttt
     8221 tttttttttt ttaatttgta tagaccatgt ggtcgctctg aactctcttc atttcagcca
     8281 tctcccaggc cattttcact acccttgaaa cttcactttc cacatatcca gcttgaagag
     8341 aaaagatttc taaaaggatt ccatgtgtat ttaggccttc tccaaccatc tgccttatga
     8401 ggttcaccca tttccaaaca aaggttttaa atacggtgac tgttcttgga tttgcaagaa
     8461 tgtacaacca gcaggtcccc ttttgcagta aagggcatta tacttgaagg ggcatactca
     8521 ttttttcctc aggtcagagg cagagggaag agttaacagt gatcaaatag agaccttcat
     8581 gtgtctgttt tttgtttttg tttttaagtt catttaaggg tgatgacgga gaaagaaggg
     8641 agtaaaaatg atgcgcgcac aaagaaattt ttcccattgc ttgccagatt cattcttttt
     8701 aggctaccct tactccagtc cttacctaca ccctaaagaa ctgtatttag ctagcaagag
     8761 aggcattctc aggatacgtg agcttccagg catggactaa catgtggttt caaatcaata
     8821 gtgtattcta acagaaaagc gttacttaat cttaattctc cattatgtga taaaataatc
     8881 tatagaaata ggtatcactt tggccagttc tgtgcatgta gctgaaaaaa aaatgtgaca
     8941 catttctgtt gtatgatttg ctatgatttt ggtttcctga gacatttgtt ccctacagtc
     9001 ttgaatatga aattctgtgt aaataatatg actatgcatt tttgctgaaa aacaaatgta
     9061 tgaaataaga ataaattatt tgtaagcaca
//
