LOCUS       XM_047431693            6247 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein associated with LIN7 1, MAGUK p55
            family member (PALS1), transcript variant X6, mRNA.
ACCESSION   XM_047431693
VERSION     XM_047431693.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6247
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..6247
                     /gene="PALS1"
                     /gene_synonym="MPP5"
                     /note="protein associated with LIN7 1, MAGUK p55 family
                     member; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 22 ESTs, 1113 long SRA
                     reads, 13 Proteins, and 97% coverage of the annotated
                     genomic feature by RNAseq alignments, including 1 sample
                     with support for all annotated introns"
                     /db_xref="GeneID:64398"
                     /db_xref="HGNC:HGNC:18669"
                     /db_xref="MIM:606958"
     CDS             1115..3142
                     /gene="PALS1"
                     /gene_synonym="MPP5"
                     /codon_start=1
                     /product="protein PALS1 isoform X1"
                     /protein_id="XP_047287649.1"
                     /db_xref="GeneID:64398"
                     /db_xref="HGNC:HGNC:18669"
                     /db_xref="MIM:606958"
                     /translation="MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLG
                     TRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP
                     MFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQ
                     NAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQ
                     ALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD
                     SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP
                     SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA
                     YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY
                     NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA
                     SAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV
                     INSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREI
                     IEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR"
ORIGIN      
        1 agccaggcgg gcttcctcag gcgcgcgagc tgcggccgtg gagggtgtga gcccaacctt
       61 tgtccctcgg agcaacgctg cctgcgcggt gcccgctcct tctgcttggc tgggcatgca
      121 ccttggcgcg ggccacagcc agccgagccc gaggtgcagg gggcgcggcg gggagtcgtc
      181 tgccccctgc gccctctctc cgaggtcgcg acgcgcggga ctctcccggc cgggtctggg
      241 aaatcggcga gggaacgctt tcctttagaa gtcagaatgt agtcagcgtt cctctgcctg
      301 actcagctgc tgattttaag tttcttaagg atacggactc tgcctcagca gcctttttct
      361 tgacaatgac tatccaagtt tttggtacca agtgggtact cgccttgttg aatgaaaagt
      421 aagctgtaaa tcacttgaag ttagaagttg gaatctctgg ccgggcgcag tggctcacac
      481 ctgtaatccc agcactttgg gaggccaagg cgggcagatc acgaggtcaa gagattgaga
      541 ccatcctagc caacatggtg aaacctcttc tctactaaaa atacaaaaat tagctgggtg
      601 tggtggcgca cgcctgtagt cccagctact caggaggctg aggcaggaga atcgcttgaa
      661 cctgggaggc ggaggttgca gtgagccagg attgtgccac tgcactccag cctggcaaca
      721 gagcgagact ccatctctca aaaaaaaaaa aagttcgaat ctcttataat gcttttttag
      781 aagcctgaca cttcagacac gtttttcagg gaaggtaatt gattaaaggg aatgaagaaa
      841 atctgcatgg agtacattga gagcaaagca atagccataa taagaaagcc ttgagttttg
      901 tgaaaaaccg gagaagagaa actaaaagga cagtagaaaa ggcttttcca gtttgcataa
      961 tatttccttc atggatactt tttcatagca ttattatgtg atgtgagaag tttttttttt
     1021 tgaagtaaca tggattttat actacagaat caagagaatt ggcttatagg aaaaattgat
     1081 ttataaaaag tggtacaggt tttcatagat aaccatgaca acatcccata tgaatgggca
     1141 tgttacagag gaatcagaca gcgaagtaaa aaatgttgat cttgcatcac cagaggaaca
     1201 tcagaagcac cgagagatgg ctgttgactg ccctggagat ttgggcacca ggatgatgcc
     1261 aatacgtcga agtgcacagt tggagcgtat tcggcaacaa caggaggaca tgaggcgtag
     1321 gagagaggaa gaagggaaaa agcaagaact tgaccttaat tcttccatga gacttaagaa
     1381 actagcccaa attcctccaa agaccggaat agataaccct atgtttgata cagaggaagg
     1441 aattgtctta gaaagtcctc attatgctgt gaaaatatta gaaatagaag acttgttttc
     1501 ttcacttaaa catatccaac atactttggt agattctcag agccaggagg atatttcact
     1561 gcttttacaa cttgttcaaa ataaggattt ccagaatgca tttaagatac acaatgccat
     1621 cacagtacac atgaacaagg ccagtcctcc atttcctctt atctccaacg cacaagatct
     1681 tgctcaagag gtacaaactg ttttgaagcc agttcatcat aaggaaggac aagaactaac
     1741 tgctttgctg aatactccac atattcaggc acttttactg gcccacgata aggttgctga
     1801 gcaggaaatg cagctagagc ccattacaga tgagagagtt tatgaaagta ttggccagta
     1861 tggaggagaa actgtaaaaa tagttcgtat agaaaaggct cgtgatattc cgttgggtgc
     1921 tacagttcgt aatgaaatgg actctgtcat cattagccgg atagtaaaag ggggtgctgc
     1981 agagaaaagt ggtctgttgc atgaaggaga tgaagttcta gagattaatg gcattgaaat
     2041 tcgggggaaa gatgtcaatg aggtttttga cttgttgtct gatatgcatg gtactttgac
     2101 ttttgtcctg attcccagtc aacagatcaa gccgcctcct gccaaggaaa cagtaatcca
     2161 tgtaaaagct cattttgact atgacccctc agatgaccct tatgttccat gtcgagagtt
     2221 aggtctgtct tttcaaaaag gtgatatact tcatgtgatc agtcaagaag atccaaactg
     2281 gtggcaggcc tacagggaag gggacgaaga taatcaacct ctagccgggc ttgttccagg
     2341 gaaaagcttt cagcagcaaa gggaagccat gaaacaaacc atagaagaag ataaggagcc
     2401 agaaaaatca ggaaaactgt ggtgtgcaaa gaagaataaa aagaagagga aaaaggtttt
     2461 atataatgcc aataaaaatg atgattatga caacgaggag atcttaacct atgaggaaat
     2521 gtcactttat catcagccag caaataggaa gagacctatc atcttgattg gtccacagaa
     2581 ctgtggccag aatgaattgc gtcagaggct catgaacaaa gaaaaggacc gctttgcatc
     2641 tgcagttcct catacaaccc ggagtaggcg agaccaagaa gtagccggta gagattacca
     2701 ctttgtttcg cggcaagcat tcgaggcaga catagcagct ggaaagttca ttgagcatgg
     2761 tgaatttgag aagaatttgt atggaactag catagattct gtacggcaag tgatcaactc
     2821 tggcaaaata tgtcttttaa gtcttcgtac acagtcattg aagactctcc ggaattcaga
     2881 tttgaaacca tatattatct tcattgcacc cccttcacaa gaaagacttc gggcattatt
     2941 ggccaaagaa ggcaagaatc caaagcctga agagttgaga gaaatcattg agaagacaag
     3001 agagatggag cagaacaatg gccactactt tgatacggca attgtgaatt ccgatcttga
     3061 taaagcctat caggaattgc ttaggttaat taacaaactt gatactgaac ctcagtgggt
     3121 accatccact tggctgaggt gaaagaaaca tccattctgt ggcatgttgg acttgatctg
     3181 gcaaaaactg ccaataggag gactgcccga cactgcagca agattgagga taagatggaa
     3241 ggcagcagta taagctgtag atctgttctt agatctcttg aattagtgag acgacagttc
     3301 ccttaggcag tttgtgcatg gcatccttta ttctctatac atggctttag cggttcttgc
     3361 ctcattttgg gattctaaat ggaagctttc aacagagcat tccattttgt cctgttaaaa
     3421 ccttttgttt tcacctaaac cctttctgct tagttgtatc tctgtgaaaa acttgtatac
     3481 acaagcgtcc atgtctcaca caaatattga tgtgattatt cttaagtgtt aaatcattaa
     3541 cacttaaatg acttcattgg gaatattgag cagagggact gtgcttctat gcactgggca
     3601 aggcagtatt tgcttaggaa actaatttag tcatcagaga tactttccta aaaaggaaaa
     3661 ataaaaaaca aaatggtgcc actttgggtt gaagctactt tgttaggctt gaattcattt
     3721 atatgtcttt tgattcttaa aaaaacaaaa aacattccat tagaagcacc agtttttttg
     3781 ctcagacttt gtggatcaga ctctacactc aacacactct aatctactta aaggtataca
     3841 aaatatgctg atctttttta aattatgatt tcctgaattt ttttcttaag tcgtctcaac
     3901 tgatttactc acttagcttc ccttccctca tcagcatagt ataatagaat gtatgttaca
     3961 tttttatgaa tggcaggtgt tcattataat ctgtattgac ttaaaaagtt tcttcctcat
     4021 gatgctaata gttttttgta tacatgggag gatagcacat ttgacagttt ttgcattttt
     4081 atgtatgagc acagtatcct atgactgtgc tacgtatata taggtaataa actggaattc
     4141 tgttgatgaa tatagctgct gtactgtata ttaatattta atagatcaac aaatggtcat
     4201 tgaaaacact tgtttagcat tagaataaaa ttatatatgt ccttgggaaa tattatgaca
     4261 gttgacttta agatcaaaag gaagggaaga cctgaaagtc atttgaacat tttaggaaaa
     4321 gaatattgga gagaaaaagg tattaaatat atagaaatag gtttttaacc taacaaggtc
     4381 tgcctcttat gacgagaatg caacagcttg gtaaatcata aaagaaacat ttaagctaat
     4441 aggattttcg tactgtctct atagctgtag ctttaaaatt caacgtatat aattggcatg
     4501 gaaacttaat ttgcagtctt ttcaagcctt taggatagtg tgatgtgtaa caaacaacct
     4561 caaatgtgaa tgccttgatt ttatttttat ggtgacttta gctacagcat ttcctatacc
     4621 cagagctaaa cactggaata atactgacat catttaattt aacataagca attatgttta
     4681 aggagtaatt tgtgtcatgt acatatttga ttgatttttt ttcttctaca taattttatt
     4741 tgaacaaatg tagacagttt atatgtcgcc tttttctgtt caaatttgca tggcctatta
     4801 agttggctgg agagtgtttt atgtggaaat attttcaaga taatgttcct taggaagaaa
     4861 ataacattct tgggttgagg gaaggaatgc catacactac tgtctcttca gatctgaaat
     4921 actccagttt agagccagga aatttcacag gtcacaccga tttttagcat taaaaactaa
     4981 ggaatatact tagcacttac ttaatctttt cagttttcca gtttacgtct caggaatgaa
     5041 gtgtagtcta tggttgacaa tggagttttg tgatcctgct tattgtaact gacaactgtt
     5101 ttcaactcca agagctaaac tattggcagt tcatgttaag ttagagtgag ggtgtaggta
     5161 gtgtcagtga gtggctcttg tgcctgctgt agacattagg cctgcactag ggccatgtgc
     5221 tgtcaagatt caggaacatg gctttaacaa gcagatcttg tatcaaggca gaggtgatgc
     5281 catgccatac ttttaggaag tctgagatga taaatatttc aaggtcagtg aagtctatca
     5341 atcattctcc ccttcctcat cagcaatggt agatagaaat gtcctaaact tttctaaatc
     5401 ctagtgatga ggatgtgctg atattcaaca tagtccttaa agtgaaaact gagttgttgc
     5461 tgacctccac aaaagaatat ggaaaaaagc cttgctgtac acctagttgt acagccactc
     5521 tggccaattc catttcctgt ccctctgtgg ttctgactgg agaccccagt gtgggggagg
     5581 tcttaccatt taatatagaa atgatatcaa taactaatgc tatgtacttg gaaaatccaa
     5641 ataaggaagt tttaggttgg tgcataactt tgtttctcaa attttcgttg tcagaacaaa
     5701 tggaaggaga atattattta gactaatcca gatttgcttt ctatgaaaat ctaatgtctg
     5761 gattatcttc cttttctcat ggcctaagaa ataaggatca ataaggaatg atttgaatgt
     5821 aattttgtga atgtgtggaa aatataaagc agggatttag ccttaataaa ggtaaccttc
     5881 tgacatctgt tgttaatccc cctttgtact cttttcctgt atctgcactg ttattttgag
     5941 atgtcatact gtacactgta ttgtaaaaat aaaaagtaaa attatatttc aaattttaaa
     6001 agccactaag caatttctct tgctatttgc tcggccactc aaggtttcca cacatgtaaa
     6061 gaccaccctc ctcttcaagt ttttgccaaa agcaagacca ttggatcctc cagctacaac
     6121 acaaaatact ttttgatttg ttctttacag agggatagtg ccccctgttg gcacaggtat
     6181 aggtaggtcc tgtttcctta attattaaaa ccaacaacta agtgtattaa agatggacaa
     6241 cgcaagg
//
