LOCUS       XM_024449691            5343 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein associated with LIN7 1, MAGUK p55
            family member (PALS1), transcript variant X7, mRNA.
ACCESSION   XM_024449691
VERSION     XM_024449691.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024449691.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5343
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..5343
                     /gene="PALS1"
                     /gene_synonym="MPP5"
                     /note="protein associated with LIN7 1, MAGUK p55 family
                     member; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 23 ESTs, 1042 long SRA
                     reads, 3 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 36 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:64398"
                     /db_xref="HGNC:HGNC:18669"
                     /db_xref="MIM:606958"
     CDS             313..2238
                     /gene="PALS1"
                     /gene_synonym="MPP5"
                     /codon_start=1
                     /product="protein PALS1 isoform X2"
                     /protein_id="XP_024305459.1"
                     /db_xref="GeneID:64398"
                     /db_xref="HGNC:HGNC:18669"
                     /db_xref="MIM:606958"
                     /translation="MAVDCPGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQE
                     LDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQH
                     TLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQ
                     TVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGE
                     TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR
                     GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRE
                     LGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEED
                     KEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL
                     IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA
                     GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
                     SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL
                     INKLDTEPQWVPSTWLR"
ORIGIN      
        1 attctttatc cggaatttca agggccgccg gagggctgtc gcttctgcag tgcgtaggag
       61 cggccggggc gggaggctcc gcggagccga ggcgtggaga ttttaagttt cttaaggata
      121 cggactctgc ctcagcagcc tttttcttga caatgactat ccaagttttt ggtaccaagt
      181 gggtactcgc cttgttgaat gaaaagaata agaaagcctt gagttttgtg aaaaaccgga
      241 gaagagaaac taaaaggaca gtagaaaagg cttttccagt ttgcataata ggaacatcag
      301 aagcaccgag agatggctgt tgactgccct ggagatttgg gcaccaggat gatgccaata
      361 cgtcgaagtg cacagttgga gcgtattcgg caacaacagg aggacatgag gcgtaggaga
      421 gaggaagaag ggaaaaagca agaacttgac cttaattctt ccatgagact taagaaacta
      481 gcccaaattc ctccaaagac cggaatagat aaccctatgt ttgatacaga ggaaggaatt
      541 gtcttagaaa gtcctcatta tgctgtgaaa atattagaaa tagaagactt gttttcttca
      601 cttaaacata tccaacatac tttggtagat tctcagagcc aggaggatat ttcactgctt
      661 ttacaacttg ttcaaaataa ggatttccag aatgcattta agatacacaa tgccatcaca
      721 gtacacatga acaaggccag tcctccattt cctcttatct ccaacgcaca agatcttgct
      781 caagaggtac aaactgtttt gaagccagtt catcataagg aaggacaaga actaactgct
      841 ttgctgaata ctccacatat tcaggcactt ttactggccc acgataaggt tgctgagcag
      901 gaaatgcagc tagagcccat tacagatgag agagtttatg aaagtattgg ccagtatgga
      961 ggagaaactg taaaaatagt tcgtatagaa aaggctcgtg atattccgtt gggtgctaca
     1021 gttcgtaatg aaatggactc tgtcatcatt agccggatag taaaaggggg tgctgcagag
     1081 aaaagtggtc tgttgcatga aggagatgaa gttctagaga ttaatggcat tgaaattcgg
     1141 gggaaagatg tcaatgaggt ttttgacttg ttgtctgata tgcatggtac tttgactttt
     1201 gtcctgattc ccagtcaaca gatcaagccg cctcctgcca aggaaacagt aatccatgta
     1261 aaagctcatt ttgactatga cccctcagat gacccttatg ttccatgtcg agagttaggt
     1321 ctgtcttttc aaaaaggtga tatacttcat gtgatcagtc aagaagatcc aaactggtgg
     1381 caggcctaca gggaagggga cgaagataat caacctctag ccgggcttgt tccagggaaa
     1441 agctttcagc agcaaaggga agccatgaaa caaaccatag aagaagataa ggagccagaa
     1501 aaatcaggaa aactgtggtg tgcaaagaag aataaaaaga agaggaaaaa ggttttatat
     1561 aatgccaata aaaatgatga ttatgacaac gaggagatct taacctatga ggaaatgtca
     1621 ctttatcatc agccagcaaa taggaagaga cctatcatct tgattggtcc acagaactgt
     1681 ggccagaatg aattgcgtca gaggctcatg aacaaagaaa aggaccgctt tgcatctgca
     1741 gttcctcata caacccggag taggcgagac caagaagtag ccggtagaga ttaccacttt
     1801 gtttcgcggc aagcattcga ggcagacata gcagctggaa agttcattga gcatggtgaa
     1861 tttgagaaga atttgtatgg aactagcata gattctgtac ggcaagtgat caactctggc
     1921 aaaatatgtc ttttaagtct tcgtacacag tcattgaaga ctctccggaa ttcagatttg
     1981 aaaccatata ttatcttcat tgcaccccct tcacaagaaa gacttcgggc attattggcc
     2041 aaagaaggca agaatccaaa gcctgaagag ttgagagaaa tcattgagaa gacaagagag
     2101 atggagcaga acaatggcca ctactttgat acggcaattg tgaattccga tcttgataaa
     2161 gcctatcagg aattgcttag gttaattaac aaacttgata ctgaacctca gtgggtacca
     2221 tccacttggc tgaggtgaaa gaaacatcca ttctgtggca tgttggactt gatctggcaa
     2281 aaactgccaa taggaggact gcccgacact gcagcaagat tgaggataag atggaaggca
     2341 gcagtataag ctgtagatct gttcttagat ctcttgaatt agtgagacga cagttccctt
     2401 aggcagtttg tgcatggcat cctttattct ctatacatgg ctttagcggt tcttgcctca
     2461 ttttgggatt ctaaatggaa gctttcaaca gagcattcca ttttgtcctg ttaaaacctt
     2521 ttgttttcac ctaaaccctt tctgcttagt tgtatctctg tgaaaaactt gtatacacaa
     2581 gcgtccatgt ctcacacaaa tattgatgtg attattctta agtgttaaat cattaacact
     2641 taaatgactt cattgggaat attgagcaga gggactgtgc ttctatgcac tgggcaaggc
     2701 agtatttgct taggaaacta atttagtcat cagagatact ttcctaaaaa ggaaaaataa
     2761 aaaacaaaat ggtgccactt tgggttgaag ctactttgtt aggcttgaat tcatttatat
     2821 gtcttttgat tcttaaaaaa acaaaaaaca ttccattaga agcaccagtt tttttgctca
     2881 gactttgtgg atcagactct acactcaaca cactctaatc tacttaaagg tatacaaaat
     2941 atgctgatct tttttaaatt atgatttcct gaattttttt cttaagtcgt ctcaactgat
     3001 ttactcactt agcttccctt ccctcatcag catagtataa tagaatgtat gttacatttt
     3061 tatgaatggc aggtgttcat tataatctgt attgacttaa aaagtttctt cctcatgatg
     3121 ctaatagttt tttgtataca tgggaggata gcacatttga cagtttttgc atttttatgt
     3181 atgagcacag tatcctatga ctgtgctacg tatatatagg taataaactg gaattctgtt
     3241 gatgaatata gctgctgtac tgtatattaa tatttaatag atcaacaaat ggtcattgaa
     3301 aacacttgtt tagcattaga ataaaattat atatgtcctt gggaaatatt atgacagttg
     3361 actttaagat caaaaggaag ggaagacctg aaagtcattt gaacatttta ggaaaagaat
     3421 attggagaga aaaaggtatt aaatatatag aaataggttt ttaacctaac aaggtctgcc
     3481 tcttatgacg agaatgcaac agcttggtaa atcataaaag aaacatttaa gctaatagga
     3541 ttttcgtact gtctctatag ctgtagcttt aaaattcaac gtatataatt ggcatggaaa
     3601 cttaatttgc agtcttttca agcctttagg atagtgtgat gtgtaacaaa caacctcaaa
     3661 tgtgaatgcc ttgattttat ttttatggtg actttagcta cagcatttcc tatacccaga
     3721 gctaaacact ggaataatac tgacatcatt taatttaaca taagcaatta tgtttaagga
     3781 gtaatttgtg tcatgtacat atttgattga ttttttttct tctacataat tttatttgaa
     3841 caaatgtaga cagtttatat gtcgcctttt tctgttcaaa tttgcatggc ctattaagtt
     3901 ggctggagag tgttttatgt ggaaatattt tcaagataat gttccttagg aagaaaataa
     3961 cattcttggg ttgagggaag gaatgccata cactactgtc tcttcagatc tgaaatactc
     4021 cagtttagag ccaggaaatt tcacaggtca caccgatttt tagcattaaa aactaaggaa
     4081 tatacttagc acttacttaa tcttttcagt tttccagttt acgtctcagg aatgaagtgt
     4141 agtctatggt tgacaatgga gttttgtgat cctgcttatt gtaactgaca actgttttca
     4201 actccaagag ctaaactatt ggcagttcat gttaagttag agtgagggtg taggtagtgt
     4261 cagtgagtgg ctcttgtgcc tgctgtagac attaggcctg cactagggcc atgtgctgtc
     4321 aagattcagg aacatggctt taacaagcag atcttgtatc aaggcagagg tgatgccatg
     4381 ccatactttt aggaagtctg agatgataaa tatttcaagg tcagtgaagt ctatcaatca
     4441 ttctcccctt cctcatcagc aatggtagat agaaatgtcc taaacttttc taaatcctag
     4501 tgatgaggat gtgctgatat tcaacatagt ccttaaagtg aaaactgagt tgttgctgac
     4561 ctccacaaaa gaatatggaa aaaagccttg ctgtacacct agttgtacag ccactctggc
     4621 caattccatt tcctgtccct ctgtggttct gactggagac cccagtgtgg gggaggtctt
     4681 accatttaat atagaaatga tatcaataac taatgctatg tacttggaaa atccaaataa
     4741 ggaagtttta ggttggtgca taactttgtt tctcaaattt tcgttgtcag aacaaatgga
     4801 aggagaatat tatttagact aatccagatt tgctttctat gaaaatctaa tgtctggatt
     4861 atcttccttt tctcatggcc taagaaataa ggatcaataa ggaatgattt gaatgtaatt
     4921 ttgtgaatgt gtggaaaata taaagcaggg atttagcctt aataaaggta accttctgac
     4981 atctgttgtt aatccccctt tgtactcttt tcctgtatct gcactgttat tttgagatgt
     5041 catactgtac actgtattgt aaaaataaaa agtaaaatta tatttcaaat tttaaaagcc
     5101 actaagcaat ttctcttgct atttgctcgg ccactcaagg tttccacaca tgtaaagacc
     5161 accctcctct tcaagttttt gccaaaagca agaccattgg atcctccagc tacaacacaa
     5221 aatacttttt gatttgttct ttacagaggg atagtgcccc ctgttggcac aggtataggt
     5281 aggtcctgtt tccttaatta ttaaaaccaa caactaagtg tattaaagat ggacaacgca
     5341 agg
//
