LOCUS       NM_001017931             812 bp    mRNA    linear   PRI 05-AUG-2024
DEFINITION  Homo sapiens PAGE family member 3 (PAGE3), transcript variant 2,
            mRNA.
ACCESSION   NM_001017931 NR_033460 XM_060054
VERSION     NM_001017931.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 812)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 812)
  AUTHORS   Brinkmann,U., Vasmatzis,G., Lee,B., Yerushalmi,N., Essand,M. and
            Pastan,I.
  TITLE     PAGE-1, an X chromosome-linked GAGE-like gene that is expressed in
            normal and neoplastic prostate, testis, and uterus
  JOURNAL   Proc Natl Acad Sci U S A 95 (18), 10757-10762 (1998)
   PUBMED   9724777
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL158819.14.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 18, 2020 this sequence version replaced NM_001017931.2.
            
            Summary: This gene is a member of family of proteins that are
            expressed in a variety of tumors and in some fetal and reproductive
            tissues. Multiple alternatively spliced transcript variants have
            been observed. [provided by RefSeq, Jan 2015].
            
            Transcript Variant: This variant (2) uses an alternate splice site
            in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode
            the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC140001.1, DB514537.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000374951.6/ ENSP00000364089.1
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-371               AL158819.14        85576-85946         c
            372-463             AL158819.14        84850-84941         c
            464-572             AL158819.14        84281-84389         c
            573-698             AL158819.14        81564-81689         c
            699-812             AL158819.14        79445-79558         c
FEATURES             Location/Qualifiers
     source          1..812
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.21"
     gene            1..812
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /note="PAGE family member 3"
                     /db_xref="GeneID:139793"
                     /db_xref="HGNC:HGNC:4110"
                     /db_xref="MIM:300739"
     exon            1..371
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /inference="alignment:Splign:2.1.0"
     exon            372..463
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             380..721
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /note="G antigen, family D, 1; G antigen family D member
                     1; prostate-associated gene 3 protein; P antigen family,
                     member 3 (prostate associated)"
                     /codon_start=1
                     /product="P antigen family member 3"
                     /protein_id="NP_001017931.3"
                     /db_xref="CCDS:CCDS35307.1"
                     /db_xref="GeneID:139793"
                     /db_xref="HGNC:HGNC:4110"
                     /db_xref="MIM:300739"
                     /translation="MSGHQRTRSRSRERRDDQDSNHPVGAVVAQELPSNDQLQQEEPP
                     IESQDYTPGQERDEGALDFQVLGLAAYLWELTRSKTGGERGDGPNVKGEFLPNLEPVK
                     IPEAGEGQPSV"
     exon            464..572
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /inference="alignment:Splign:2.1.0"
     exon            573..698
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /inference="alignment:Splign:2.1.0"
     exon            699..812
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      787..792
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /note="hexamer: AATAAA"
     polyA_site      812
                     /gene="PAGE3"
                     /gene_synonym="CT16.6; GAGED1; PAGE-3"
                     /note="major polyA site"
ORIGIN      
        1 ttgctgtctg ctgtctgctg tctgctgtct gcgctcagag ctctgccctg agaggtggtc
       61 ctcctgtcct cttcattctt tctcactgac tgggactcag ctggtaggtc cgcagatcag
      121 tcctcctggg aatttagttg tgagtgaatg tgaaggggag ccagcgggct ttggacaggt
      181 cctgcggcac agaaaccaca gtccgtggct tctgagagaa aagggcctcg ccgtcgacgt
      241 ccggctcctc ccaggtcgcg acgccccatg ggcctttgtc gtcgtttctg ggccaggacg
      301 acggaggaag gtggaccgta gaggggagga atcacgtgaa gatggggcga gtgctgggcg
      361 tgctgttgga gagtgaaaca tgagtggaca tcaaagaaca agatccagat ctagagaaag
      421 aagagatgat caagactcta atcatccagt aggggctgtg gttgcccagg agctgcccag
      481 taatgaccag cttcaacaag aggaaccacc aattgaaagt caggattata cacctggtca
      541 agagagagac gagggagcac tggacttcca agtgctaggc ctggcagcct atctctggga
      601 actgactcgg tcaaagactg ggggtgaacg tggagatggt cctaatgtca agggagaatt
      661 tctgccaaat ctggagcctg ttaaaatacc agaagcaggt gaagggcaac catcggttta
      721 aatgaagaca agctgaaacc atacatgcag tctttatgtt ggaaacttca ccagtaaaat
      781 tctctcaata aagtttcaca attgtctgca aa
//
