LOCUS       NM_207339                541 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens PAGE family member 2 (PAGE2), mRNA.
ACCESSION   NM_207339
VERSION     NM_207339.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Yilmaz-Ozcan,S., Sade,A., Kucukkaraduman,B., Kaygusuz,Y.,
            Senses,K.M., Banerjee,S. and Gure,A.O.
  TITLE     Epigenetic mechanisms underlying the dynamic expression of
            cancer-testis genes, PAGE2, -2B and SPANX-B, during
            mesenchymal-to-epithelial transition
  JOURNAL   PLoS One 9 (9), e107905 (2014)
   PUBMED   25229454
  REMARK    GeneRIF: Epigenetic mechanisms underlying the dynamic expression of
            cancer-testis genes, PAGE2, -2B and SPANX-B, during
            mesenchymal-to-epithelial transition
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  AUTHORS   Lee,O.H., Kim,H., He,Q., Baek,H.J., Yang,D., Chen,L.Y., Liang,J.,
            Chae,H.K., Safari,A., Liu,D. and Songyang,Z.
  TITLE     Genome-wide YFP fluorescence complementation screen identifies new
            regulators for telomere signaling in human cells
  JOURNAL   Mol Cell Proteomics 10 (2), M110.001628 (2011)
   PUBMED   21044950
REFERENCE   3  (bases 1 to 541)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
REFERENCE   4  (bases 1 to 541)
  AUTHORS   Brinkmann,U., Vasmatzis,G., Lee,B., Yerushalmi,N., Essand,M. and
            Pastan,I.
  TITLE     PAGE-1, an X chromosome-linked GAGE-like gene that is expressed in
            normal and neoplastic prostate, testis, and uterus
  JOURNAL   Proc Natl Acad Sci U S A 95 (18), 10757-10762 (1998)
   PUBMED   9724777
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL590240.5, AA815378.1, BC054022.1 and BX113994.1.
            
            On May 17, 2019 this sequence version replaced NM_207339.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC054022.1, HY035996.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000374968.9/ ENSP00000364107.4
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                AL590240.5         39953-39986
            35-46               AA815378.1         447-458             c
            47-372              BC054022.1         7-332
            373-535             BX113994.1         269-431
            536-541             AL590240.5         43772-43777
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.21"
     gene            1..541
                     /gene="PAGE2"
                     /gene_synonym="CT16.4; GAGEC2; GAGEE2; PAGE-2"
                     /note="PAGE family member 2"
                     /db_xref="GeneID:203569"
                     /db_xref="HGNC:HGNC:31804"
                     /db_xref="MIM:300738"
     exon            1..86
                     /gene="PAGE2"
                     /gene_synonym="CT16.4; GAGEC2; GAGEE2; PAGE-2"
                     /inference="alignment:Splign:2.1.0"
     exon            87..178
                     /gene="PAGE2"
                     /gene_synonym="CT16.4; GAGEC2; GAGEE2; PAGE-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..430
                     /gene="PAGE2"
                     /gene_synonym="CT16.4; GAGEC2; GAGEE2; PAGE-2"
                     /note="G antigen, family E, 2; g antigen family E member
                     2; prostate-associated gene 2 protein; G antigen family C
                     2; P antigen family, member 2 (prostate associated)"
                     /codon_start=1
                     /product="P antigen family member 2"
                     /protein_id="NP_997222.1"
                     /db_xref="CCDS:CCDS14367.1"
                     /db_xref="GeneID:203569"
                     /db_xref="HGNC:HGNC:31804"
                     /db_xref="MIM:300738"
                     /translation="MSELLRARSQSSERGNDQESSQPVGSVIVQEPTEEKRQEEEPPT
                     DNQGIAPSGEIENQAVPAFQGPDMEAFQQELALLKIEDEPGDGPDVREGIMPTFDLTK
                     VLEAGDAQP"
     exon            179..287
                     /gene="PAGE2"
                     /gene_synonym="CT16.4; GAGEC2; GAGEE2; PAGE-2"
                     /inference="alignment:Splign:2.1.0"
     exon            288..413
                     /gene="PAGE2"
                     /gene_synonym="CT16.4; GAGEC2; GAGEE2; PAGE-2"
                     /inference="alignment:Splign:2.1.0"
     exon            414..541
                     /gene="PAGE2"
                     /gene_synonym="CT16.4; GAGEC2; GAGEE2; PAGE-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtccgcac agaggtctgc aaggagagag agtgtcttca ttctttccgc catcttgatt
       61 ctttctcact gaccaagact cagccgtggg aaatatgagt gagcttctaa gagcaagatc
      121 ccaatcctca gaaagaggaa atgaccaaga gtcttcccag ccggttggat ctgtgattgt
      181 ccaggagccc actgaggaaa aacgtcaaga agaggaacca ccaactgata atcagggtat
      241 tgcacctagt ggggagattg aaaatcaagc agtgcctgct tttcaagggc ctgacatgga
      301 agcttttcaa caggaactgg ctctgcttaa gatagaggat gagcctggag atggtcctga
      361 tgtcagggag ggtattatgc ccacttttga tctcactaaa gtgctggaag caggtgatgc
      421 gcaaccatag gtttcaagca agacaaatga agactgaaac caagaacgtt attcttaatc
      481 tggaaatttg actgataata ttctcttaat aaagttttaa gttttctgca aagaatcctt
      541 a
//
