LOCUS       XM_047424317            2361 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens proton activated chloride channel 1
            (PACC1), transcript variant X3, mRNA.
ACCESSION   XM_047424317
VERSION     XM_047424317.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2361
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2361
                     /gene="PACC1"
                     /gene_synonym="ASOR; C1orf75; hPAC; hTMEM206; PAC; PAORAC;
                     TMEM206"
                     /note="proton activated chloride channel 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 23 ESTs, 367 long SRA reads, and 98% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     20 samples with support for all annotated introns"
                     /db_xref="GeneID:55248"
                     /db_xref="HGNC:HGNC:25593"
                     /db_xref="MIM:618427"
     CDS             130..1074
                     /gene="PACC1"
                     /gene_synonym="ASOR; C1orf75; hPAC; hTMEM206; PAC; PAORAC;
                     TMEM206"
                     /codon_start=1
                     /product="proton-activated chloride channel isoform X3"
                     /protein_id="XP_047280273.1"
                     /db_xref="GeneID:55248"
                     /db_xref="HGNC:HGNC:25593"
                     /db_xref="MIM:618427"
                     /translation="MIRQERSTSYQELSEELVQVVENSELADEQDKETVRVQGPGILP
                     GLDSESASSSIRFSKACLKNVFSVLLIFIYLLLMAVAVFLVYRTITDFREKLKHPVMS
                     VSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLTSPGQPGDMNCTTQRINYTDPF
                     SNQTVKSALIVQGPREVKKRELVFLQFRLNKSSEDFSAIDYLLFSSFQEFLQSPNRVG
                     FMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQEIVTANPWNTIALLCG
                     AFLALFKAAEFAKLSIKWMIKIRKRYLKRRGQATSHIS"
ORIGIN      
        1 ctctgggacg cccctccgga ccggtttcgc ctcgcggagc cggtaggtcc aggtgcagcg
       61 gccgcagtgc tgcgtccgtg cgccgcgggc tggggcggtc tcaggtgtgc cgaagctctg
      121 gtcagtgcca tgatccggca ggagcgctcc acatcctacc aggagctgag tgaggagttg
      181 gtccaggtgg ttgagaactc agagctggca gacgagcagg acaaggagac ggtcagagtc
      241 caaggtccgg gtatcttacc aggcctggac agcgagtccg cctccagcag catccgcttc
      301 agcaaggcct gcctgaagaa cgtcttctcg gtcctactca tcttcatcta cctgctgctc
      361 atggctgtgg ccgtcttcct ggtctaccgg accatcacag actttcgtga gaaactcaag
      421 caccctgtca tgtctgtgtc ttacaaggaa gtggatcgct atgatgcccc aggtattgcc
      481 ttgtaccccg gtcaggccca gttgctcagc tgtaagcacc attacgaggt cattcctcct
      541 ctgacaagcc ctggccagcc gggtgacatg aattgcacca cccagaggat caactacacg
      601 gaccccttct ccaatcagac tgtgaaatct gccctgattg tccaggggcc ccgggaagtg
      661 aaaaagcggg agctggtctt cctccagttc cgcctgaaca agagtagtga ggacttcagc
      721 gccattgatt acctcctctt ctcttctttc caggagttcc tgcaaagccc aaacagggta
      781 ggcttcatgc aggcctgtga gagtgcctat tccagctgga agttctctgg gggcttccgc
      841 acctgggtca agatgtcact ggtaaagacc aaggaggagg atgggcggga agcagtggag
      901 ttccggcagg agatagtcac tgccaatcct tggaacacaa ttgctcttct ctgtggcgcc
      961 ttcttggcat tatttaaagc agcagagttt gccaaactga gtataaaatg gatgatcaaa
     1021 attagaaaga gataccttaa aagaagaggt caggcaacga gccacataag ctgaagtcac
     1081 ctcgcgttgt ttagagaact gtccacatca atgggagctg tcatcacttc cactttgtaa
     1141 acggagctat caacaatcct gtactcactt gaagaaatgg ggccttgctg ggaggaacag
     1201 catgtaaaac tggaacttct aaccccgtcc caaaagaggc ggtgtagagc ctaatagaag
     1261 agactaatgg ataaacctac aagttattta aatatttaaa ttattaataa actttttaaa
     1321 gagctggcca atgacttttg aatagggttt gtagaagatg cctttcttcc tgtttggttc
     1381 attgtattgt attaggttaa gctctactag ggtaatgaag gctctacttt tcacttttta
     1441 aaagtggaca aaagagtgtg attttctttt tccaaaaatt cctgagtatc aagacgtgca
     1501 ggtcatgctt tggagcctat gcactgtaca caaaggcaaa accctatgac tttggcatca
     1561 tctgccattg atgtccagcc tctgacatgc tctttgattt gttaaatgtt aaatgagact
     1621 ttaaggctac tagaaactag taattaagtt tcttaatgga ctgagtagcc acctacttgt
     1681 ccggctagaa tgtttgttga tgtatgagtt tagattaaca ctcaaaagca ctaggacaga
     1741 tgtacataga aggtgcctac tcattgtatt ttgatgattt cattaacagg taaataaaag
     1801 ttaatacaaa aggaacgagt gtgacaatat gaatatctgc tcaatcatcg ggcacaatta
     1861 ctttcatttg gtgacttcca aggacaaaaa ggtagtatga gtctggactc ccaagatgga
     1921 tctgactccc aaggtatgtt ctaactgctt ccagggaagg gtttgttagg catggcaact
     1981 gatggcaggt gtccagaaag agtgacctgg tgtccccgag gaagctgggt taactcttta
     2041 ctgtgtccac aaaactaccc atcatatgag gaaggggcat acgcagtgtg accctcaaaa
     2101 agcttttagc ctagcctttg acagaaatga gtatgcatta aaaaaaagtc tatttttcac
     2161 attaaggttc taaaaattgt ttccagagtt ttaaattatt tatgtgcctg ttgcttcaaa
     2221 gaggacttgg tagcatttcc taaattttgt aatctggctt ccgataatcc aaagggaata
     2281 actcaaatgt atgaataggc attttaaatg ggaagaaact gttttttgga tgaatgatta
     2341 aaagtgaact gtataaagaa a
//
