LOCUS       NM_001388447            1592 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens PABIR family member 3 (PABIR3), transcript variant 23,
            mRNA.
ACCESSION   NM_001388447 XM_006724734
VERSION     NM_001388447.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1592)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 1592)
  AUTHORS   Hasegawa,Y., Taylor,D., Ovchinnikov,D.A., Wolvetang,E.J., de
            Torrente,L. and Mar,J.C.
  TITLE     Variability of Gene Expression Identifies Transcriptional
            Regulators of Early Human Embryonic Development
  JOURNAL   PLoS Genet 11 (8), e1005428 (2015)
   PUBMED   26288249
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL691477.9 and Z83826.13.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 3, 2020 this sequence version replaced XM_006724734.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR18074968.332488.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1965299, SAMEA1968968 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000645433.2/ ENSP00000496338.1
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               AL691477.9         30011-30115
            106-274             AL691477.9         30314-30482
            275-353             AL691477.9         37545-37623
            354-410             Z83826.13          4651-4707
            411-454             Z83826.13          20630-20673
            455-509             Z83826.13          20772-20826
            510-602             Z83826.13          22808-22900
            603-691             Z83826.13          23308-23396
            692-753             Z83826.13          24592-24653
            754-850             Z83826.13          28225-28321
            851-1592            Z83826.13          29516-30257
FEATURES             Location/Qualifiers
     source          1..1592
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq26.3"
     gene            1..1592
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /note="PABIR family member 3"
                     /db_xref="GeneID:159091"
                     /db_xref="HGNC:HGNC:25202"
     exon            1..105
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            106..274
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..977
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /note="isoform 12 is encoded by transcript variant 23;
                     protein FAM122C; family with sequence similarity 122C;
                     PABIR family member 1"
                     /codon_start=1
                     /product="PABIR family member 1 isoform 12"
                     /protein_id="NP_001375376.1"
                     /db_xref="CCDS:CCDS94672.1"
                     /db_xref="GeneID:159091"
                     /db_xref="HGNC:HGNC:25202"
                     /translation="MAQEKMKLGFKSLPSSTTADGNILRRVNSAPLINGLGFNSQVLQ
                     ADMLRIRTNRTTFRNRRSLLLPPPPFHGSISRLHQIKQEEAMDLINRETMSEWKLQSE
                     IQISHSWEEGLKLNDNGLQKSSSLKCIDLTPVSSMASSIKKTGKQCFSPSLQTCVSCT
                     GSPSSPIPSPMQQYIIRSQNPTNIIRPSILGPLKRKGEMAFQYQPKKIFQGTTNMLSS
                     DTSQLSENNVYLLPATFDGNDSNAGSSGNSSAEIGTVTNSPVSPSDTGSHLF"
     exon            275..353
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            354..410
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            411..454
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            455..509
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            510..602
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            603..691
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            692..753
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            754..850
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     exon            851..1592
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1323..1328
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /note="hexamer: AATATA"
     regulatory      1345..1350
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /note="hexamer: AGTAAA"
     polyA_site      1351
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /note="major polyA site"
     polyA_site      1371
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /note="major polyA site"
     regulatory      1566..1571
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
                     /note="hexamer: ATTAAA"
     polyA_site      1592
                     /gene="PABIR3"
                     /gene_synonym="FAM122C"
ORIGIN      
        1 gttttggccg gaaaggctta ccatgagttg ccagggctga gagagatgga gaaggattcg
       61 cggcggtgac agattaaatt ccccagttac attatagact tggagacttg tccttgtgtg
      121 gacgggagcc ggaaagcctt gagaacttat tcctcgaccc ggacatggca caggagaaaa
      181 tgaaactagg tttcaagtcg ctgccgagtt ccactaccgc agacggcaac attctgagaa
      241 gagtcaacag tgcccctttg atcaatggac ttggttttaa ttcacaggtg ttgcaagctg
      301 acatgttaag aattaggaca aacagaacaa catttaggaa tcgacgctct ctgttgttgc
      361 cacctcctcc ctttcatggt tccatcagcc gccttcatca aatcaaacag gaagaagcca
      421 tggatttaat aaatagagaa acaatgtctg aatggaagct acaaagtgag atacagataa
      481 gtcactcttg ggaagaaggc ttgaaactga atgacaatgg cttacagaaa tcatcctctc
      541 taaagtgcat tgatttaact ccagtatcct caatggcttc ttccatcaag aagactggga
      601 agcagtgttt ctctccatca ttacaaactt gtgtgagttg cactggttcg ccttcaagtc
      661 ctattcccag tcctatgcaa caatacatca taagaagtca aaatcctacc aacattatta
      721 gaccaagtat ccttggacca ttaaaaagaa aaggtgaaat ggcatttcaa tatcaaccaa
      781 aaaagatttt ccaaggcaca accaacatgc tttcttctga tacttcccaa ctgtcagaaa
      841 ataatgtgta tctacttcca gctacttttg atggaaacga cagcaatgct ggatcttctg
      901 gtaattcgtc agctgaaatc ggcactgtca caaactctcc tgtgtcacct tctgatactg
      961 gttctcattt gttctagtag acaaactttc aactaaatga ttcacccatc ccaagacttt
     1021 ctcaccagtg gagaaacaca cacatcaagc aaaccaagtc agagcaatga gaattgtact
     1081 gtataattta aactatctcc tatttatctt ttttcctcaa tttcctaaaa ttctatttat
     1141 ctacagaact tgcgtgtata attcttgtgt acatccttaa atttaatgta ataacatgtt
     1201 aaagatgttt tccaaatcag aaccatgttg aagatacaag cgtaaattgt taggctgcta
     1261 ttttctagaa aatgctgtac cttgactttt taaaataatc ttatgaaaca taattctgat
     1321 aaaatataat tgttcaatta acaaagtaaa atgatgtttg acaattatgt acttaatgat
     1381 ccatgctagt ctttaatgct attttcagta actactagct tccacttggt aaagaaaagt
     1441 cacatatcaa aggcaatttt tatgactaag ttataccata ctgatccaag gattgcttat
     1501 tttgcacatg aatccttaga tattcaattt gttgggaagc agtaggtagg agaagagcaa
     1561 gacaaattaa agttaattga atagaaagaa aa
//
