LOCUS       NM_001328655             405 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens PIK3R3 upstream open reading frame (P3R3URF), mRNA.
ACCESSION   NM_001328655
VERSION     NM_001328655.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB047431.1 and BX106694.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001328655.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX106694.1, AI208897.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2158188 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000506599.2/ ENSP00000480059.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                DB047431.1         8-22
            16-405              BX106694.1         1-390
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.1"
     gene            1..405
                     /gene="P3R3URF"
                     /note="PIK3R3 upstream open reading frame"
                     /db_xref="GeneID:110117498"
                     /db_xref="HGNC:HGNC:53451"
     exon            1..261
                     /gene="P3R3URF"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..305
                     /gene="P3R3URF"
                     /note="PIK3R3 upstream reading frame"
                     /codon_start=1
                     /product="PIK3R3 upstream open reading frame protein"
                     /protein_id="NP_001315584.1"
                     /db_xref="CCDS:CCDS85970.1"
                     /db_xref="GeneID:110117498"
                     /db_xref="HGNC:HGNC:53451"
                     /translation="MGPSRLVRGPRPQGMRSPYRRPGMGWPRPRFPRMFKCSRRRYQQ
                     GLRGRTASSAAINPATRAMGINNTHTDTTIVWIFPPQVLRHLRQPGIFLIL"
     exon            262..405
                     /gene="P3R3URF"
                     /inference="alignment:Splign:2.1.0"
     regulatory      385..390
                     /regulatory_class="polyA_signal_sequence"
                     /gene="P3R3URF"
                     /note="hexamer: AATACA"
     polyA_site      405
                     /gene="P3R3URF"
                     /note="major polyA site"
ORIGIN      
        1 agaagctccc tgtgcccatg gggccatctc ggcttgtccg tggccctcgg ccccagggca
       61 tgcgttcccc ctaccgcagg ccaggtatgg gctggcccag gccccgattt cccaggatgt
      121 tcaagtgtag ccgcagaaga tatcaacagg gtctccgagg tcgaactgcc agcagtgcag
      181 ccatcaatcc tgccaccagg gccatgggta tcaacaacac ccacactgac accaccatag
      241 tgtggatctt cccacctcaa gttctcagac atctcaggca acctgggatt tttctgatcc
      301 tctagaagtg cccagaagct agcccagaag cttggtttgc cctggacctg catctcctag
      361 gggccgtgtg ggtggtgaac aacaaataca gtcattctgc tcaaa
//
