LOCUS       NM_001005243            3120 bp    mRNA    linear   PRI 24-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 9 subfamily K member 2
            (OR9K2), mRNA.
ACCESSION   NM_001005243 XM_497345
VERSION     NM_001005243.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3120)
  AUTHORS   Goodbourn,P.T., Bosten,J.M., Bargary,G., Hogg,R.E.,
            Lawrance-Owen,A.J. and Mollon,J.D.
  TITLE     Variants in the 1q21 risk region are associated with a visual
            endophenotype of autism and schizophrenia
  JOURNAL   Genes Brain Behav 13 (2), 144-151 (2014)
   PUBMED   24152035
REFERENCE   2  (bases 1 to 3120)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC027287.21.
            
            On Aug 13, 2020 this sequence version replaced NM_001005243.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000641329.1/ ENSP00000493006.1
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               AC027287.21        141390-141500
            112-195             AC027287.21        141812-141895
            196-3120            AC027287.21        144810-147734
FEATURES             Location/Qualifiers
     source          1..3120
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.2"
     gene            1..3120
                     /gene="OR9K2"
                     /gene_synonym="OR12-2"
                     /note="olfactory receptor family 9 subfamily K member 2"
                     /db_xref="GeneID:441639"
                     /db_xref="HGNC:HGNC:15339"
     exon            1..111
                     /gene="OR9K2"
                     /gene_synonym="OR12-2"
                     /inference="alignment:Splign:2.1.0"
     exon            112..195
                     /gene="OR9K2"
                     /gene_synonym="OR12-2"
                     /inference="alignment:Splign:2.1.0"
     exon            196..3120
                     /gene="OR9K2"
                     /gene_synonym="OR12-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..1146
                     /gene="OR9K2"
                     /gene_synonym="OR12-2"
                     /note="olfactory receptor OR12-2"
                     /codon_start=1
                     /product="olfactory receptor 9K2"
                     /protein_id="NP_001005243.2"
                     /db_xref="CCDS:CCDS31814.2"
                     /db_xref="GeneID:441639"
                     /db_xref="HGNC:HGNC:15339"
                     /translation="MGDRGTSNHSEMTDFILAGFRVRPELHILLFLLFLFVYAMILLG
                     NVGMMTIIMTDPRLNTPMYFFLGNLSFIDLFYSSVIEPKAMINFWSENKSISFAGCVA
                     QLFLFALLIVTEGFLLAAMAYDRFIAICNPLLYSVQMSTRLCTQLVAGSYFCGCISSV
                     IQTSMTFTLSFCASRAVDHFYCDSRPLQRLSCSDLFIHRMISFSLSCIIILPTIIVII
                     VSYMYIVSTVLKIHSTEGHKKAFSTCSSHLGVVSVLYGAVFFMYLTPDRFPELSKVAS
                     LCYSLVTPMLNPLIYSLRNKDVQEALKKFLEKKNIIL"
ORIGIN      
        1 agagctcagg acctctactt gcatatccat ggcaatctat cctcttgcct tgaaagcata
       61 caagtttctg agaattcagg atagataata tcttgtggat tgattcctca gaattaaaac
      121 aataaacaga ggaaaacatt ggaactctgc tgattgattt ttaccagaat ctgaccagtt
      181 actaaacaat acaaggtttc taccatgggt gacaggggaa caagcaatca ctcagaaatg
      241 actgacttca ttcttgcagg cttcagggta cgcccagagc tccacattct cctcttcctg
      301 ctatttttgt ttgtttatgc catgatcctt ctagggaatg ttgggatgat gaccattatt
      361 atgactgatc ctcggctgaa cacaccaatg tattttttcc taggcaatct ctccttcatt
      421 gatcttttct attcatctgt tattgaaccc aaggctatga tcaacttctg gtctgaaaac
      481 aagtctatct cctttgcagg ctgtgtggcc cagctctttc tctttgccct cctcattgtg
      541 actgagggat ttctcctggc ggccatggct tatgaccgct ttattgccat ctgcaaccct
      601 ctgctctact ctgttcaaat gtccacacgt ctgtgtactc agttggtggc tggttcctat
      661 ttttgtggct gcattagctc agttattcag actagcatga catttacttt atctttttgc
      721 gcttctcggg ctgttgacca cttttactgt gattctcgcc cacttcagag actgtcttgt
      781 tctgatctct ttatccatag aatgatatct ttttccttat catgtattat tatcttgcct
      841 actatcatag tcattatagt atcttacatg tatattgtgt ccacagttct aaagatacat
      901 tctactgagg gacataagaa ggccttctcc acctgcagct ctcacctggg agttgtgagt
      961 gtgctgtatg gtgctgtctt ttttatgtat ctcactcctg acagatttcc tgagctgagt
     1021 aaagtggcat ccttatgtta ctccctagtc actcccatgt tgaatccttt gatttactct
     1081 ctgaggaaca aagatgtcca agaggctcta aaaaaatttc tagagaagaa aaatattatt
     1141 ctttgattat tatttctctt tcaccaattt tattgtggct atttatttaa tacacctgtg
     1201 ttcattaata aaagttactc tcccgaatgt cataaaaata ctcttagatg ttttcatgtg
     1261 atgtgctctt tccatatttt acttttttac ctcccaagac atcattaatt ctgaaaatct
     1321 tggatattgg agatatcctg gacattagag aagtattttc atgataaacc ctctcactgg
     1381 tcttcaacat tttatttcac agaatttata tctattgatt cttgtggcat aatgtagaac
     1441 aatattttgt attttgttat agtgcttcag caagatttta tctggtgttt gtctttggga
     1501 ttgcccatcc ctcctacaca caatcatggg tagttgacaa agatgcccag attattttta
     1561 aataaaatat gtctttaatt ttatagctag tttcattagc atgctaaatg agtattcagt
     1621 tttcacctta tgtgtgctag ataggaagta ctaataataa gaaacaaact ataagtaatc
     1681 tttatacatt aatttggaaa atgttgtact tcattattgt ggagtgctct aaggtactgc
     1741 tagttgctga atcccagtgc aaagaactaa aataggaaat agagatcttc aaacattttg
     1801 atcaatcatg ccctcaattt tgatcttcat gattttgtct tgtgttaata attgataagg
     1861 aatagttaat aaaggtatag aatcagggaa gtcatcaaaa cggattatga tccaaaattt
     1921 acttatctat gcctcttaat ataggtatat atttgattaa tcttattgaa tatctgtata
     1981 atatgttctg gccttacagt gggctcaggg ataaataacc tcattctttt gaaagtttaa
     2041 aagttagtga gatactgaaa tccttgggca taaaaccaaa atccagacat tttgccaaag
     2101 gtactcatag agatcacaaa gtggggtgcc tgaaagaagg tggttggtaa tcagagaaac
     2161 ccttcttggg ctgcatggaa cattgcgcaa agggggatta gattgaagtc aggaaacctg
     2221 ctgcagtggt ttataatatt gatgtgggct caatggtatg tcgatattaa tgaacaaagg
     2281 cagatttttt aaactgcagg taaaagaccc aaaatatatt aactgactag tatgaagaga
     2341 atgtacaaaa gatggtatgt tagcccattt ttgaaattga gtgtgtgcat ggtcatggtc
     2401 tgaatagata aaaagtatag gagctctcag aaaacctgaa ataaaggggg aactttcttg
     2461 ccttgatgaa catgtatgaa aaacctacag tgaacatttt aaatgacaag aaactagaag
     2521 ctttcctact attatcagga aaaatgcaag gatgccttct ctcaccacac cttttcaata
     2581 ttttaatgga agtgctagcc aatgcaacaa aatgagaaaa ggaaataaaa gtgttatggg
     2641 ttgaatggta ttccctcaaa attcatgtgt tgaagcccta aaccctagta cttcagaatg
     2701 tgactttaat tagtgatagg gtcttcaaag atgtaattga gttaaaataa ggctgtaaga
     2761 taaatcctaa ttcagtatca tttgtgtccc tatagaaaga ggagattagg gcacacagag
     2821 ggacaccagg ggtgcatgtg cacagaacat cagtcatgtg aagaatcaac aagagggcag
     2881 ccatctgcaa gctaaggaaa gagggctcag agaaaaccaa ctctgctgac accttgatct
     2941 tgggcttcca gcctctatca ctaagaaaat taatttctgt tgtttaagaa cccagtgtgt
     3001 ggtgttttgt tatgggatct ccagcaaatt catacaaata ggtctataaa ttggaaaaga
     3061 agagaaaacg ttccttgttt gcagataaca tatctatgta gaaaattaaa aataataaac
//
