LOCUS       NM_001004744             975 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily U member 3
            (OR8U3), mRNA.
ACCESSION   NM_001004744 XM_166831
VERSION     NM_001004744.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 975)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 975)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 975)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AP002512.4.
            
            On Sep 19, 2004 this sequence version replaced XM_166831.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000623286.1/ ENSP00000485324.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-975               AP002512.4         58434-59408         c
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..975
                     /gene="OR8U3"
                     /gene_synonym="OR11-185; OR5R1; OR5R1P"
                     /note="olfactory receptor family 8 subfamily U member 3"
                     /db_xref="GeneID:219479"
                     /db_xref="HGNC:HGNC:14841"
     CDS             1..975
                     /gene="OR8U3"
                     /gene_synonym="OR11-185; OR5R1; OR5R1P"
                     /note="olfactory receptor, family 5, subfamily R, member 1
                     pseudogene; olfactory receptor 5R1; olfactory receptor
                     OR11-185; olfactory receptor family 5 subfamily R member
                     1"
                     /codon_start=1
                     /product="olfactory receptor 8U3"
                     /protein_id="NP_001004744.1"
                     /db_xref="GeneID:219479"
                     /db_xref="HGNC:HGNC:14841"
                     /translation="MAEVNIIYVTVFILKGITNRPELQAPCFGVFLVIYLVTVLGNLG
                     LITLIKIDTRLHTPMYYFLSHLAFVDLCYSSAITPKMMVNFVVERNTIPFHACATQLG
                     CFLTFMITECFLLASMAYDCYVAICSPLHYSTLMSRRVCIQLVAVPYIYSFLVALFHT
                     VITFRLTYCGPNLINHFYCDDLPFLALSCSDTHMKEILIFAFAGFDMISSSSIVLTSY
                     IFIIAAILRIRSTQGQHKAISTCGSHMVTVTIFYGTLIFMYLQPKSNHSLDTDKMASV
                     FYTVVIPMLNPLIYSLRNKEVKDASKKALDKGCENLQILTFLKIRKLY"
     exon            1..975
                     /gene="OR8U3"
                     /gene_synonym="OR11-185; OR5R1; OR5R1P"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctgaag ttaatatcat ttatgtcact gtattcattc tgaaaggaat taccaaccgg
       61 ccagagcttc aggccccgtg ctttggggtg tttttagtta tctatctggt cacagtgctg
      121 ggcaatcttg ggttgattac tttaatcaag attgatactc gactccacac acctatgtac
      181 tatttcctca gccacctggc ctttgttgac ctttgttact cctctgctat tacaccgaag
      241 atgatggtga attttgttgt ggaacgcaac accattcctt tccatgcttg tgcaacccaa
      301 ctgggttgtt ttctcacctt catgatcact gagtgtttcc ttctagcctc catggcctac
      361 gattgctatg tcgccatctg tagtcccctg cattattcaa cactgatgtc aagaagagtc
      421 tgcattcaac tggtggcagt tccatatata tacagcttcc tggttgccct cttccacacc
      481 gttatcactt tccgtctgac ttactgtggc ccaaacttaa ttaaccattt ctattgtgat
      541 gacctcccct tcttagctct gtcctgctca gacacacaca tgaaggaaat tctgatattt
      601 gcctttgctg gctttgatat gatctcttcc tcttccattg tcctcacctc ctacatcttt
      661 attattgccg ctatcctaag gatccgctct actcaggggc aacacaaagc catttccacc
      721 tgtggctccc atatggtgac tgtcactatt ttctatggca cactgatctt tatgtaccta
      781 cagcccaaat caaatcactc cttggacaca gacaagatgg cttctgtatt ttacacagtg
      841 gtgatcccca tgttaaaccc cctaatctat agtctaagga acaaagaagt gaaagatgcc
      901 tcaaagaaag ccttggataa aggttgtgaa aacttacaga tattaacatt tttaaaaata
      961 agaaaacttt attaa
//
