LOCUS       NM_001390849             939 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily S member 1
            (OR8S1), mRNA.
ACCESSION   NM_001390849
VERSION     NM_001390849.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Wu,Y., Gao,H., Li,H., Tabara,Y., Nakatochi,M., Chiu,Y.F.,
            Park,E.J., Wen,W., Adair,L.S., Borja,J.B., Cai,Q., Chang,Y.C.,
            Chen,P., Croteau-Chonka,D.C., Fogarty,M.P., Gan,W., He,C.T.,
            Hsiung,C.A., Hwu,C.M., Ichihara,S., Igase,M., Jo,J., Kato,N.,
            Kawamoto,R., Kuzawa,C.W., Lee,J.J., Liu,J., Lu,L., McDade,T.W.,
            Osawa,H., Sheu,W.H., Teo,Y., Vadlamudi,S., Van Dam,R.M., Wang,Y.,
            Xiang,Y.B., Yamamoto,K., Ye,X., Young,T.L., Zheng,W., Zhu,J.,
            Shu,X.O., Shin,C., Jee,S.H., Chuang,L.M., Miki,T., Yokota,M.,
            Lin,X., Mohlke,K.L. and Tai,E.S.
  TITLE     A meta-analysis of genome-wide association studies for adiponectin
            levels in East Asians identifies a novel locus near WDR11-FGFR2
  JOURNAL   Hum Mol Genet 23 (4), 1108-1119 (2014)
   PUBMED   24105470
REFERENCE   2  (bases 1 to 939)
  AUTHORS   Shimada,M., Miyagawa,T., Kawashima,M., Tanaka,S., Honda,Y.,
            Honda,M. and Tokunaga,K.
  TITLE     An approach based on a genome-wide association study reveals
            candidate loci for narcolepsy
  JOURNAL   Hum Genet 128 (4), 433-441 (2010)
   PUBMED   20677014
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC089987.26.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641651.1/ ENSP00000493379.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-939               AC089987.26        85015-85953         c
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.11"
     gene            1..939
                     /gene="OR8S1"
                     /note="olfactory receptor family 8 subfamily S member 1"
                     /db_xref="GeneID:341568"
                     /db_xref="HGNC:HGNC:19628"
     CDS             1..939
                     /gene="OR8S1"
                     /codon_start=1
                     /product="olfactory receptor 8S1"
                     /protein_id="NP_001377778.1"
                     /db_xref="CCDS:CCDS91690.1"
                     /db_xref="GeneID:341568"
                     /db_xref="HGNC:HGNC:19628"
                     /translation="MALGNHSTITEFLLLGLSADPNIRALLFVLFLGIYLLTIMENLM
                     LLLMIRADSCLHKPMYFFLSHLSFVDLCFSSVIVPKMLENLLSQRKTISVEGCLAQVF
                     FVFVTAGTEACLLSGMAYDRHAAICRPLLYGQIMGKQLYMHLVWGSWGLGFLDALINV
                     LLAVNMVFCEAKIIHHYSYEMPSLLPLSCSDISRSLIALLCSTLLHGLGNFLLVFLSY
                     TRIISTILSISSTSGRSKAFSTCSAHLTAVTLYYGSGLLRHLMPNSGSPIELIFSVQY
                     TVVTPMLNSLIYSLKNKEVKVALKRTLEKYLQYTRR"
     exon            1..939
                     /gene="OR8S1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggccttgg ggaatcacag caccatcacc gagttcctcc tccttgggct gtctgccgac
       61 cccaacatcc gggctctgct ctttgtgctg ttcctgggga tttacctcct gaccataatg
      121 gaaaacctga tgctgctgct catgatcagg gctgattctt gtctccataa gcccatgtat
      181 ttcttcctga gtcacctctc ttttgttgat ctctgcttct cttcagtcat tgtgcccaag
      241 atgctggaga acctcctgtc acagaggaaa accatttcag tagagggctg cctggctcag
      301 gtcttctttg tgtttgtcac tgcagggact gaagcctgcc ttctctcagg gatggcctat
      361 gaccgccatg ctgccatctg ccgcccacta ctttatggac agatcatggg taaacagctg
      421 tatatgcacc ttgtgtgggg ctcatgggga ctgggctttc tggacgcact catcaatgtc
      481 ctcctagctg taaacatggt cttttgtgaa gccaaaatca ttcaccacta cagctatgag
      541 atgccatccc tcctccctct gtcctgctct gatatctcca gaagcctcat cgccttgctc
      601 tgctccactc tcctacatgg gctgggaaac ttccttttgg tcttcttatc ctacacccgt
      661 ataatctcta ccatcctaag catcagctct acctcgggca gaagcaaggc cttctccacc
      721 tgctctgccc acctcactgc agtgacactt tactatggct caggtttgct ccgccatctc
      781 atgccaaact caggttcccc catagagttg atcttctctg tgcagtatac tgtagtcact
      841 cccatgctga attccctcat ctatagcctg aaaaataagg aagtgaaggt agctctgaaa
      901 agaactttgg aaaaatattt gcaatatacc agacgttga
//
