LOCUS       NM_001005202            2438 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 8 subfamily K member 3
            (gene/pseudogene) (OR8K3), mRNA.
ACCESSION   NM_001005202 XM_166825
VERSION     NM_001005202.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Olender,T., Waszak,S.M., Viavant,M., Khen,M., Ben-Asher,E.,
            Reyes,A., Nativ,N., Wysocki,C.J., Ge,D. and Lancet,D.
  TITLE     Personal receptor repertoires: olfaction as a model
  JOURNAL   BMC Genomics 13, 414 (2012)
   PUBMED   22908908
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2438)
  AUTHORS   Menashe,I., Aloni,R. and Lancet,D.
  TITLE     A probabilistic classifier for olfactory receptor pseudogenes
  JOURNAL   BMC Bioinformatics 7, 393 (2006)
   PUBMED   16939646
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2438)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC022882.5.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jan 13, 2021 this sequence version replaced NM_001005202.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. This olfactory receptor gene is a
            segregating pseudogene, where some individuals have an allele that
            encodes a functional olfactory receptor, while other individuals
            have an allele encoding a protein that is predicted to be
            non-functional. [provided by RefSeq, Jun 2015].
            
            Sequence Note: This gene is a segregating pseudogene. This RefSeq
            represents the protein encoded by the reference genome allele,
            which is predicted to be non-functional as an olfactory receptor
            according to the Classifier for Olfactory Receptor Pseudogenes.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641662.1/ ENSP00000493271.1
            polymorphic pseudogene :: PMID: 22908908
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                AC022882.5         125893-125916
            25-82               AC022882.5         126749-126806
            83-2438             AC022882.5         129033-131388
FEATURES             Location/Qualifiers
     source          1..2438
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..2438
                     /gene="OR8K3"
                     /gene_synonym="OR11-181"
                     /note="olfactory receptor family 8 subfamily K member 3
                     (gene/pseudogene)"
                     /db_xref="GeneID:219473"
                     /db_xref="HGNC:HGNC:15313"
     exon            1..24
                     /gene="OR8K3"
                     /gene_synonym="OR11-181"
                     /inference="alignment:Splign:2.1.0"
     exon            25..82
                     /gene="OR8K3"
                     /gene_synonym="OR11-181"
                     /inference="alignment:Splign:2.1.0"
     exon            83..2438
                     /gene="OR8K3"
                     /gene_synonym="OR11-181"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..1044
                     /gene="OR8K3"
                     /gene_synonym="OR11-181"
                     /note="olfactory receptor OR11-181; olfactory receptor,
                     family 8, subfamily K, member 3"
                     /codon_start=1
                     /product="olfactory receptor 8K3"
                     /protein_id="NP_001005202.1"
                     /db_xref="GeneID:219473"
                     /db_xref="HGNC:HGNC:15313"
                     /translation="MEQHNLTTVNEFILTGITDIAELQAPLFALFLMIYVISVMGNLG
                     MIVLTKLDSRLQTPMYFFLRHLAFMDLGYSTTVGPKMLVNFVVDKNIISYYFCATQLA
                     FFLVFIGSELFILSAMSYDLYVAICNPLLYTVIMSRRVCQVLVAIPYLYCTFISLLVT
                     IKIFTLSFCGYNVISHFYCDSLPLLPLLCSNTHEIELIILIFAAIDLISSLLIVLLSY
                     LLILVAILRMNSAGRQKAFSTCGAHLTVVIVFYGTLLFMYVQPKSSHSFDTDKVASIF
                     YTLVIPMLNPLIYSLRNKDVKYALRRTWNNLCNIFV"
ORIGIN      
        1 gtcaagacag aggcttcctt acagaactcc aaagatggtg aaaggaacct catttatatt
       61 tccttaccta acaagaaaac agaataggtt ttctgatgaa cctggatgga acaacacaat
      121 ctaacaacgg tgaatgaatt cattcttacg ggaatcacag atatcgctga gctgcaggca
      181 ccattatttg cattgttcct catgatctat gtgatctcag tgatgggcaa tttgggcatg
      241 attgtcctca ccaagttgga ctccaggttg caaaccccta tgtacttttt tctcagacat
      301 ctggctttca tggatcttgg ttattcaaca actgtgggac ccaaaatgtt agtaaatttt
      361 gttgtggata agaatataat ttcttattat ttttgtgcaa cacagctagc tttctttctt
      421 gtgttcattg gtagtgaact ttttattctc tcagccatgt cctacgacct ctatgtggcc
      481 atctgtaacc ctctgctata cacagtaatc atgtcacgaa gggtatgtca ggtgctggta
      541 gcaatccctt acctctattg cacattcatt tctcttctag tcaccataaa gatttttact
      601 ttatccttct gtggctacaa cgtcattagt catttctact gtgacagtct ccctttgtta
      661 cctttgcttt gttcaaatac acatgaaatt gaattgataa ttctgatctt tgcagctatt
      721 gatttgattt catctcttct gatagttctt ttatcttacc tgctcatcct tgtagccatt
      781 ctcaggatga attctgctgg cagacaaaag gctttttcta cctgtggagc ccacctgaca
      841 gtggtcatag tgttctatgg gactttgctt ttcatgtacg tgcagcccaa gtccagtcat
      901 tcctttgaca ctgataaagt ggcttccata ttttacaccc tggttatccc catgttgaat
      961 cccttgatct atagtttacg aaacaaagat gtaaaatatg ccctacgaag gacatggaat
     1021 aacttatgta atatttttgt ttaaattttg tacaatatga ttcctataaa ttaggttatg
     1081 ggcatgaatt tttgctctgc atacttccag aagacataac aagcataact gattcaacat
     1141 atatttacat atgtctcata catgataggc tcttctaatt gctatacata gattaataaa
     1201 caaaatagta gaaatctttg ccttccttga tggatagatg aattgtattc acaataagtc
     1261 cattttatat aacagtagaa tgtgcacgat ggatatagac aaagaaaaaa gggagacaag
     1321 gaaagctagt atgctgggtg gcagtaggaa acagtggtca ttacagaagg gagttacgag
     1381 gattccagtg ttttttatct gctactggaa taaaatttac agtgtgtgtg cttctgtatg
     1441 tttctgtttg tgtgtttttg tgtatataag cattttcctt ctgttttagc cttcatactt
     1501 tttgcttgta tattctgaca ttgcatttaa tactggttgt ttagatgata tgtgatgatt
     1561 ttaagtctta cagatgtgct cgaataatta ctattccgaa tattaggatc ctactatttc
     1621 cttatcaatg tttttatttc cacatagaag tctgttaacc gaacatactt tgtagctcaa
     1681 taatcggtaa attctgatta gcacctgatt ttgtttcagt tagcccattc tgtttacatg
     1741 agtagatata tcaattatgc ttaagtttag aagacatcca tagaaattct caggtttatt
     1801 ctttctctct agttgttctt gcttaataac tgcctttttc acagattttc ccgttattta
     1861 tctaaaaaaa agtaataaac tgtggttaaa atttgtgttc cagttgtttt tacatctttg
     1921 aggaggggga ccattctatg atgaattaac tttgtagtct ctcactgagt tgacaatcca
     1981 taatttttat caatatgcac tatatcgaat gcactatatt ttcatttact tcactgtttg
     2041 attgcatcag ttgatttttc tacttgtaca aagcaaataa aagtaataaa atgcactaca
     2101 ccatactgta tctatctgct ggctattaca gatgtccttt gacagttaca gaccttcacc
     2161 atgcaagtga ggtctgatct gtatgcaatg atatcgttat cttgcctttt aaacatggtt
     2221 gctttcctta actccatatg ttttcttatg tattttgatt tcctttattc tttttaataa
     2281 tcctaagaat ttattgaaag tatcagagtc tacaatattt tcttggttca ccatcataaa
     2341 ataaaatccc atgtgcagcc aaagaaacac taatgaatat atctcattgg aataaattaa
     2401 acattgcata gcacattgtc atgtgaggat aaatatta
//
